메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Huangqin-tang ameliorates dextran sodium sulphate-induced colitis by regulating intestinal epithelial cell homeostasis, inflammation and immune response

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; CYTOKINE; DEXTRAN SULFATE; HERBACEOUS AGENT; HUANGQIN-TANG; IMMUNOLOGIC FACTOR;

EID: 85006427602     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep39299     Document Type: Article
Times cited : (46)

References (47)
  • 2
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • Maloy, K. J., Powrie, F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 474, 298-306 (2011).
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 3
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • Cho, J. H. The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol 8, 458-66 (2008).
    • (2008) Nat Rev Immunol , vol.8 , pp. 458-466
    • Cho, J.H.1
  • 4
    • 84901385741 scopus 로고    scopus 로고
    • Sealing the broken barrier in IBD: Intestinal permeability, epithelial cells and junctions
    • Fries, W., Belvedere, A., Vetrano, S. Sealing the broken barrier in IBD: intestinal permeability, epithelial cells and junctions. Curr Drug Targets 14, 1460-70 (2013).
    • (2013) Curr Drug Targets , vol.14 , pp. 1460-1470
    • Fries, W.1    Belvedere, A.2    Vetrano, S.3
  • 5
    • 0036218221 scopus 로고    scopus 로고
    • The immunology of mucosal models of inflammation
    • Strober, W., Fuss, I. J., Blumberg, R. S. The immunology of mucosal models of inflammation. Annu Rev Immunol 20, 495-549 (2002).
    • (2002) Annu Rev Immunol , vol.20 , pp. 495-549
    • Strober, W.1    Fuss, I.J.2    Blumberg, R.S.3
  • 7
    • 84868212109 scopus 로고    scopus 로고
    • Crohn's disease
    • Baumgart, D. C., Sandborn, W. J. Crohn's disease. Lancet 380, 1590-605 (2012).
    • (2012) Lancet , vol.380 , pp. 1590-1605
    • Baumgart, D.C.1    Sandborn, W.J.2
  • 8
    • 77955039434 scopus 로고    scopus 로고
    • Molecular networks for the study of TCM pharmacology
    • Zhao, J., Jiang, P., Zhang, W. Molecular networks for the study of TCM pharmacology. Brief Bioinform 11, 417-30 (2010).
    • (2010) Brief Bioinform , vol.11 , pp. 417-430
    • Zhao, J.1    Jiang, P.2    Zhang, W.3
  • 9
    • 84946925897 scopus 로고    scopus 로고
    • A Systems Biology-Based Investigation into the Pharmacological Mechanisms of Shengma-bie-jia-tang Acting on Systemic Lupus Erythematosus by Multi-Level Data Integration
    • Huang, L., Lv, Q., Liu, F., Shi, T., Wen, C. A Systems Biology-Based Investigation into the Pharmacological Mechanisms of Shengma-bie-jia-tang Acting on Systemic Lupus Erythematosus by Multi-Level Data Integration. Sci Rep 5, 16401 (2015).
    • (2015) Sci Rep , vol.5 , pp. 16401
    • Huang, L.1    Lv, Q.2    Liu, F.3    Shi, T.4    Wen, C.5
  • 10
    • 84862777420 scopus 로고    scopus 로고
    • Old formula, new Rx: The journey of PHY906 as cancer adjuvant therapy
    • Liu, S. H., Cheng, Y. C. Old formula, new Rx: the journey of PHY906 as cancer adjuvant therapy. J Ethnopharmacol 140, 614-23 (2012).
    • (2012) J Ethnopharmacol , vol.140 , pp. 614-623
    • Liu, S.H.1    Cheng, Y.C.2
  • 11
    • 84921505603 scopus 로고    scopus 로고
    • Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis
    • Chen, P., et al. Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis. J Ethnopharmacol 162, 207-14 (2015).
    • (2015) J Ethnopharmacol , vol.162 , pp. 207-214
    • Chen, P.1
  • 12
    • 84939864179 scopus 로고    scopus 로고
    • Huangqin-Tang Ameliorates TNBS-Induced Colitis by Regulating Effector and Regulatory CD4(+ ) T Cells
    • Zou, Y., et al. Huangqin-Tang Ameliorates TNBS-Induced Colitis by Regulating Effector and Regulatory CD4(+ ) T Cells. Biomed Res Int 2015, 102021 (2015).
    • (2015) Biomed Res Int , vol.2015 , pp. 102021
    • Zou, Y.1
  • 13
    • 0025181580 scopus 로고
    • A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
    • Okayasu, I., et al. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 98, 694-702 (1990).
    • (1990) Gastroenterology , vol.98 , pp. 694-702
    • Okayasu, I.1
  • 14
    • 84908181172 scopus 로고    scopus 로고
    • Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis
    • Ahmad, R., et al. Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis. Mucosal Immunol 7, 1340-53 (2014).
    • (2014) Mucosal Immunol , vol.7 , pp. 1340-1353
    • Ahmad, R.1
  • 15
    • 84859566874 scopus 로고    scopus 로고
    • Baicalin down-regulates the expression of macrophage migration inhibitory factor (MIF) effectively for rats with ulcerative colitis
    • Dai, S. X., Zou, Y., Feng, Y. L., Liu, H. B., Zheng, X. B. Baicalin down-regulates the expression of macrophage migration inhibitory factor (MIF) effectively for rats with ulcerative colitis. Phytother Res 26, 498-504 (2012).
    • (2012) Phytother Res , vol.26 , pp. 498-504
    • Dai, S.X.1    Zou, Y.2    Feng, Y.L.3    Liu, H.B.4    Zheng, X.B.5
  • 16
    • 84899639879 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease
    • Neurath, M. F. Cytokines in inflammatory bowel disease. Nat Rev Immunol 14, 329-42 (2014).
    • (2014) Nat Rev Immunol , vol.14 , pp. 329-342
    • Neurath, M.F.1
  • 17
    • 0034078302 scopus 로고    scopus 로고
    • Dextran sulfate sodium-induced murine colitis activates NFkappaB and increases galanin-1 receptor expression
    • Marrero, J. A., Matkowskyj, K. A., Yung, K., Hecht, G., Benya, R. V. Dextran sulfate sodium-induced murine colitis activates NFkappaB and increases galanin-1 receptor expression. Am J Physiol Gastrointest Liver Physiol 278, G797-804 (2000).
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.278 , pp. G797-G804
    • Marrero, J.A.1    Matkowskyj, K.A.2    Yung, K.3    Hecht, G.4    Benya, R.V.5
  • 18
    • 0031925362 scopus 로고    scopus 로고
    • Activation of nuclear factor kappa B inflammatory bowel disease
    • Schreiber, S., Nikolaus, S., Hampe, J. Activation of nuclear factor kappa B inflammatory bowel disease. Gut 42, 477-84 (1998).
    • (1998) Gut , vol.42 , pp. 477-484
    • Schreiber, S.1    Nikolaus, S.2    Hampe, J.3
  • 19
    • 0031595210 scopus 로고    scopus 로고
    • Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa
    • Rogler, G., et al. Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa. Gastroenterology 115, 357-69 (1998).
    • (1998) Gastroenterology , vol.115 , pp. 357-369
    • Rogler, G.1
  • 20
    • 84906571227 scopus 로고    scopus 로고
    • The alarmin IL-33 promotes regulatory T-cell function in the intestine
    • Schiering, C., et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature 513, 564-8 (2014).
    • (2014) Nature , vol.513 , pp. 564-568
    • Schiering, C.1
  • 21
    • 55749091152 scopus 로고    scopus 로고
    • Regulatory T cells in inflammatory bowel disease
    • Boden, E. K., Snapper, S. B. Regulatory T cells in inflammatory bowel disease. Curr Opin Gastroenterol 24, 733-41 (2008).
    • (2008) Curr Opin Gastroenterol , vol.24 , pp. 733-741
    • Boden, E.K.1    Snapper, S.B.2
  • 22
    • 84864330113 scopus 로고    scopus 로고
    • Deletion of Foxp3+ regulatory T cells in genetically targeted mice supports development of intestinal inflammation
    • Boehm, F., et al. Deletion of Foxp3+ regulatory T cells in genetically targeted mice supports development of intestinal inflammation. BMC Gastroenterol 12, 97 (2012).
    • (2012) BMC Gastroenterol , vol.12 , pp. 97
    • Boehm, F.1
  • 23
    • 84884390272 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice
    • Xue, X., et al. Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice. Gastroenterology 145, 831-41 (2013).
    • (2013) Gastroenterology , vol.145 , pp. 831-841
    • Xue, X.1
  • 24
    • 84871986920 scopus 로고    scopus 로고
    • VSL#3 probiotics exerts the anti-inflammatory activity via PI3k/Akt and NF-kappaB pathway in rat model of DSSinduced colitis
    • Dai, C., et al. VSL#3 probiotics exerts the anti-inflammatory activity via PI3k/Akt and NF-kappaB pathway in rat model of DSSinduced colitis. Mol Cell Biochem 374, 1-11 (2013).
    • (2013) Mol Cell Biochem , vol.374 , pp. 1-11
    • Dai, C.1
  • 25
    • 77952099431 scopus 로고    scopus 로고
    • The dextran sulphate sodium (DSS) model of colitis: An overview
    • Solomon, L., et al. The dextran sulphate sodium (DSS) model of colitis: an overview. Comparative Clinical Pathology 19, 235-239 (2010).
    • (2010) Comparative Clinical Pathology , vol.19 , pp. 235-239
    • Solomon, L.1
  • 26
    • 23344449020 scopus 로고    scopus 로고
    • Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota
    • Elson, C. O., et al. Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol Rev 206, 260-76 (2005).
    • (2005) Immunol Rev , vol.206 , pp. 260-276
    • Elson, C.O.1
  • 27
    • 24744469250 scopus 로고    scopus 로고
    • Animal models of intestinal inflammation: Ineffective communication between coalition members
    • Lorenz, R. G., McCracken, V. J., Elson, C. O. Animal models of intestinal inflammation: ineffective communication between coalition members. Springer Semin Immunopathol 27, 233-47 (2005).
    • (2005) Springer Semin Immunopathol , vol.27 , pp. 233-247
    • Lorenz, R.G.1    McCracken, V.J.2    Elson, C.O.3
  • 28
    • 0242678327 scopus 로고    scopus 로고
    • Increased enterocyte apoptosis in inflamed areas of Crohn's disease
    • Di Sabatino, A., et al. Increased enterocyte apoptosis in inflamed areas of Crohn's disease. Dis Colon Rectum 46, 1498-507 (2003).
    • (2003) Dis Colon Rectum , vol.46 , pp. 1498-1507
    • Di Sabatino, A.1
  • 29
    • 0036064749 scopus 로고    scopus 로고
    • Increase in colorectal epithelial apoptotic cells in patients with ulcerative colitis ultimately requiring surgery
    • Hagiwara, C., Tanaka, M., Kudo, H. Increase in colorectal epithelial apoptotic cells in patients with ulcerative colitis ultimately requiring surgery. J Gastroenterol Hepatol 17, 758-64 (2002).
    • (2002) J Gastroenterol Hepatol , vol.17 , pp. 758-764
    • Hagiwara, C.1    Tanaka, M.2    Kudo, H.3
  • 30
    • 0029823381 scopus 로고    scopus 로고
    • Apoptosis of crypt epithelial cells in ulcerative colitis
    • Iwamoto, M., Koji, T., Makiyama, K., Kobayashi, N., Nakane, P. K. Apoptosis of crypt epithelial cells in ulcerative colitis. J Pathol 180, 152-9 (1996).
    • (1996) J Pathol , vol.180 , pp. 152-159
    • Iwamoto, M.1    Koji, T.2    Makiyama, K.3    Kobayashi, N.4    Nakane, P.K.5
  • 31
    • 59849113041 scopus 로고    scopus 로고
    • The ErbB4 growth factor receptor is required for colon epithelial cell survival in the presence of TNF
    • Frey, M. R., Edelblum, K. L., Mullane, M. T., Liang, D., Polk, D. B. The ErbB4 growth factor receptor is required for colon epithelial cell survival in the presence of TNF. Gastroenterology 136, 217-26 (2009).
    • (2009) Gastroenterology , vol.136 , pp. 217-226
    • Frey, M.R.1    Edelblum, K.L.2    Mullane, M.T.3    Liang, D.4    Polk, D.B.5
  • 32
    • 34047173496 scopus 로고    scopus 로고
    • Epithelial NEMO links innate immunity to chronic intestinal inflammation
    • Nenci, A., et al. Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature 446, 557-61 (2007).
    • (2007) Nature , vol.446 , pp. 557-561
    • Nenci, A.1
  • 33
    • 84861540381 scopus 로고    scopus 로고
    • Protective role of 1,25(OH)2 vitamin D3 in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice
    • Zhao, H., et al. Protective role of 1,25(OH)2 vitamin D3 in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice. BMC Gastroenterol 12, 57 (2012).
    • (2012) BMC Gastroenterol , vol.12 , pp. 57
    • Zhao, H.1
  • 34
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • Turner, J. R. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 9, 799-809 (2009).
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 35
    • 84862297537 scopus 로고    scopus 로고
    • Dextran sodium sulphate colitis mouse model: Traps and tricks
    • Perse, M., Cerar, A. Dextran sodium sulphate colitis mouse model: traps and tricks. J Biomed Biotechnol 2012, 718617 (2012).
    • (2012) J Biomed Biotechnol , vol.2012 , pp. 718617
    • Perse, M.1    Cerar, A.2
  • 36
    • 34347262689 scopus 로고    scopus 로고
    • Chemically induced mouse models of intestinal inflammation
    • Wirtz, S., Neufert, C., Weigmann, B., Neurath, M. F. Chemically induced mouse models of intestinal inflammation. Nat Protoc 2, 541-6 (2007).
    • (2007) Nat Protoc , vol.2 , pp. 541-546
    • Wirtz, S.1    Neufert, C.2    Weigmann, B.3    Neurath, M.F.4
  • 37
    • 84892979085 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes and their receptors: Bridging inflammation and colorectal cancer
    • Savari, S., Vinnakota, K., Zhang, Y., Sjolander, A. Cysteinyl leukotrienes and their receptors: bridging inflammation and colorectal cancer. World J Gastroenterol 20, 968-77 (2014).
    • (2014) World J Gastroenterol , vol.20 , pp. 968-977
    • Savari, S.1    Vinnakota, K.2    Zhang, Y.3    Sjolander, A.4
  • 39
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman, C., Mauze, S., Leach, M. W., Coffman, R. L., Powrie, F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 190, 995-1004 (1999).
    • (1999) J Exp Med , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 40
    • 16844365494 scopus 로고    scopus 로고
    • Tight junctions, leaky intestines, and pediatric diseases
    • Liu, Z., Li, N., Neu, J. Tight junctions, leaky intestines, and pediatric diseases. Acta Paediatr 94, 386-93 (2005).
    • (2005) Acta Paediatr , vol.94 , pp. 386-393
    • Liu, Z.1    Li, N.2    Neu, J.3
  • 41
    • 84863248698 scopus 로고    scopus 로고
    • ErbB2 and ErbB3 regulate recovery from dextran sulfate sodiuminduced colitis by promoting mouse colon epithelial cell survival
    • Zhang, Y., Dube, P. E., Washington, M. K., Yan, F., Polk, D. B. ErbB2 and ErbB3 regulate recovery from dextran sulfate sodiuminduced colitis by promoting mouse colon epithelial cell survival. Lab Invest 92, 437-50 (2012).
    • (2012) Lab Invest , vol.92 , pp. 437-450
    • Zhang, Y.1    Dube, P.E.2    Washington, M.K.3    Yan, F.4    Polk, D.B.5
  • 42
    • 34548162712 scopus 로고    scopus 로고
    • An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression
    • Neufert, C., Becker, C., Neurath, M. F. An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression. Nat Protoc 2, 1998-2004 (2007).
    • (2007) Nat Protoc , vol.2 , pp. 1998-2004
    • Neufert, C.1    Becker, C.2    Neurath, M.F.3
  • 43
  • 44
    • 13244277880 scopus 로고    scopus 로고
    • Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
    • Maeda, S., et al. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science 307, 734-8 (2005).
    • (2005) Science , vol.307 , pp. 734-738
    • Maeda, S.1
  • 45
    • 0028898281 scopus 로고
    • Disruption of colonic electrolyte transport in experimental colitis
    • Bell, C. J., Gall, D. G., Wallace, J. L. Disruption of colonic electrolyte transport in experimental colitis. Am J Physiol 268, G622-30 (1995).
    • (1995) Am J Physiol , vol.268 , pp. G622-G630
    • Bell, C.J.1    Gall, D.G.2    Wallace, J.L.3
  • 46
    • 79955501236 scopus 로고    scopus 로고
    • PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice
    • Qiu, W., et al. PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. J Clin Invest 121, 1722-32 (2011).
    • (2011) J Clin Invest , vol.121 , pp. 1722-1732
    • Qiu, W.1
  • 47
    • 0036897129 scopus 로고    scopus 로고
    • Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement
    • Okazawa, A., et al. Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement. Am J Gastroenterol 97, 3108-17 (2002).
    • (2002) Am J Gastroenterol , vol.97 , pp. 3108-3117
    • Okazawa, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.