Dextran sulfate sodium-induced murine colitis activates NF-κB and increases galanin-1 receptor expression

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 278, Issue 5 41-5, 2000, Pages

  Marrero, Jorge A ^a   Matkowskyj, Kristina A ^a   Yung, Kenny ^a   Hecht, Gail ^a   Benya, Richard V ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Galanin; Inflammatory bowel disease; Secretion

Indexed keywords

DEXTRAN SULFATE; GALANIN; GALANIN RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC INFLAMMATION; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DIARRHEA; ENTERITIS; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECRETION;

EID: 0034078302     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2000.278.5.g797     Document Type: Article

References (46)

1. Allen TC. Hematoxylin and eosin. In: Laboratory Methods in Histotechnology, edited by Prophet EB, Mills B, Arrington JB, and Sobin LH. Washington, DC: American Registry of Pathology, 1992, p. 53-58.
2. Arai Y, Takanashi H, Kitagawa H, and Okayasu I. Involvement of interleukin-1 in the development of ulcerative colitis induced by dextran sulfate sodium in mice. Cytokine 10: 890-896, 1998.
3. Ardite E, Panes J, Miranda M, Salas A, Elizalde JI, Sans M, Arce Y, Bordas JM, Fernandez-Checa JC, and Pique JM. Effects of steroid treatment on activation of nuclear factor κB in patients with inflammatory bowel disease. Br J Pharmacol 124: 431-433, 1998.
4. Bauer FE, Adrian TE, Christofides ND, Ferri GL, Yanaihara N, Polak JM, and Bloom SR. Distribution and molecular heterogeneity of galanin in human, pig, guinea pig, and rat gastrointestinal tracts. Gastroenterology 91: 877-883, 1986.
5. - secretion. Am J Physiol Gastrointest Liver Physiol 276: G64-G76, 1999.
6. - secretion in the human colon. Potential significance of inflammation-associated NF-κB activation on galanin-1 receptor expression and function. Ann NY Acad Sci 869: 64-77, 1998.
7. Bersani M, Johnsen AH, Hojrup P, Dunning BE, Andreasen JJ, and Host JJ. Human galanin: primary structure and identification of 2 molecular forms. FEBS Lett 283: 189-194, 1991.
8. Castagliuolo I, Riegler M, Pasha A, Nikulasson S, Lu B, Gerard C, Gerard NP, and Pothoulakis C. Neurokinin-1 (NK-1) receptor is required in Clostridium difficile-induced enteritis. J Clin Invest 101: 1547-1550, 1998.
9. Cooper HS, Murthy SNS, Shah RS, and Sedergran DJ. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69: 238-249, 1993.
10. Dieleman LA, Ridwan BU, Tennyson GS, Beagley KW, Bucy RP, and Elson CO. Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. Gastroenterology 107: 1643-1652, 1994.
11. Dieleman LA, Palmen MJ, Akol H, Bloemena E, Pena AS, Meuwissen SG, and Van Rees EP. Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines. Clin Exp Immunol 114: 385-391, 1998.
12. Dorries R, Schimple A, and Wecker E. Action of dextran sulfate as a direct and general B cell mitogen. Eur J Immunol 4: 230-223, 1974.
13. Dyer RB, Collaco CR, Niesel DW, and Herzog NK. Shigella flexneri invasion of HeLa cells induces NF-κB DNA binding activity. Infect Immun 61: 4427-4433, 1993.
14. Gu Z-F, Pradhan TK, Coy DH, and Jensen RT. Interaction of galanin fragments with galanin receptors on isolated smooth muscle cells from Guinea pig stomach: identification of a novel galanin receptor subtype. J Pharmacol Exp Ther 272: 371-378, 1995.
15. Gu Z-F, Rossowski WJ, Coy DH, Pradhan TK, and Jensen RT. Chimeric galanin analogs that function as antagonists in the CNS are full agonists in gastrointestinal smooth muscle. J Pharmacol Exp Ther 266: 912-918, 1993.
16. Habert-Ortoli E, Amiranoff B, Loquet I, Laburthe M, and Mayaux J-F. Molecular cloning of a functional human galanin receptor. Proc Natl Acad Sci USA 91: 9780-9783, 1994.
17. - secretion from intestinal epithelia by upregulating galanin-1 receptor expression. J Clin Invest 104: 253-262, 1999.
18. Heuillet E, Bouaiche Z, Menager J, Dugay P, Munoz N, Dubois H, Amiranoff B, Crespo A, Lavayre J, Blanchard J-C, and Doble A. The human galanin receptor: ligand-binding and functional characteristics in the Bowes melanoma cell line. Eur J Pharmacol 269: 139-147, 1994.
19. Hoyle CH and Brunstock G. Galanin-like immunoreactivity in enteric neurons of the human colon. J Anat 166: 23-33, 1989.
20. Jasani B and Schmid KW. Immunocytochemistry in Diagnostic Histopathology. Edinburgh: Churchill Livingstone, 1993.
21. Kask K, Langel U, and Bartfai T. Galanin - a neuropeptide with inhibitory actions. Cell Mol Neurobiol 15: 653-673, 1995.
22. Kim H-S and Berstad A. Experimental colitis in animal models. Scand J Gastroenterol 27: 529-537, 1992.
23. Lorimer DD and Benya RV. Cloning and quantification of human galanin-1 receptor expression by mucosal cells lining the gastrointestinal tract. Biochem Biophys Res Commun 222: 379-385, 1996.
24. Lorimer DD, Matkowskjy K, and Benya RV. Cloning, chromosomal localization, and transcriptional regulation of the human galanin-1 receptor gene (GALN1R). Biochem Biophys Res Commun 241: 558-564, 1997.
25. Matkowskyj KA, Schonfeld D, and Benya RV Quantitative immunohistochemistry by measuring cumulative signal strength using the commercially available software Photoshop and Matlab. J Histochem Cytochem 48: 303-311, 2000.
26. Neurath MF, Fuss I, Schurmann G, Pettersson S, Arnold K, Muller-Lobeck H, Strober W, Herfarth C, and Buschenfelde KH. Cytokine gene transcription by NF-κB family members in patients with inflammatory bowel disease. Ann NY Acad Sci 859: 149-159, 1998
27. Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, and Strober W. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NK-κB abrogates established experimental colitis in mice. Nat Med 2: 998-1004, 1996.
28. Okayasu I, Hatakeyama S, Yamada M, Ohkusa T, Inagaki Y, and Nakaya R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 98: 694-702, 1990
29. Patterson J, Conklin D, Murphy K, Horlick R, Largent BL, and Fitzgerald LW. Pharmacological characterization of a recombinant human galanin receptor (GalR1) in HEK293 cells (Abstract). Soc Neurosci Abstr 23: 392, 1997.
30. Rattan S. Role of galanin in the gut. Gastroenterology 100: 1762-1768, 1991.
31. Rosen T, Krikun G, Ma Y, Wang EY, Lockwood CJ, and Guller S. Chronic antagonism of nuclear factor-kappa B activity in cytotrophoblasts by dexamethasone: a potential mechanism for anti-inflammatory action of glucocorticoids in human placenta. J Clin Endocrinol Metab 83: 3647-3652, 1998.
32. Sacks M, Gordon J, Bylander J, Porter D, Shi XL, Castranova V, Kaczmarczyk W, Van Dyke K, and Reasor MJ. Silica-induced pulmonary inflammation in rats: activation of NF-κB and its suppression by dexamethasone. Biochem Biophys Res Commun 253: 181-184, 1998.
33. Sartor RB, Anderle SK, Rifai N, Goo DAT, Cromartie WJ, and Schwab JH. Protracted anemia associated with chronic, relapsing systemic inflammation induced by arthropathic peptidoglycan-polysaccharide polymers. Infect Immun 57: 1177-1185, 1989.
34. Savkovic SD, Koutsouris A, and Hecht G. Activation of NF-κB in intestinal epithelial cells by enteropathogenic Escherichia coli. Am J Physiol Cell Physiol 273: C1160-C1167, 1997.
35. Schmitz H, Barmeyer C, Fromm M, Runkel N, Foss H-D, Bentzel CJ, Riecken E-O, and Schulzke J-D. Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology 116: 301-309, 1999.
36. Schreiber S, Nikolaus S, and Hampe J. Activation of nuclear factor κB in inflammatory bowel disease. Gut 42: 477-484, 1998.
37. Tatemoto K, Rokaeus A, Jornvall H, McDonald TJ, and Mutt V. Galanin, a novel biologically active peptide from porcine intestine. FEBS Lett 164: 124-128, 1983.
38. Tessner TG, Cohn SM, Schloemann S, and Stenson WF. Protaglandins prevent decreased epithelial cell proliferation associated with dextran sodium sulfate injury in mice. Gastroenterology 115: 874-882, 1998.
39. Wahl C, Liptay S, Adler G, and Schmid RM. Sulfasalazine: a potent and specific inhibitor of nuclear factor κB. J Clin Invest 101: 1163-1174, 1998.
40. Walker MW, Smithe KE, Borowsky B, Zhou R, Shaposhnick Z, Nagorny R, Vaysse PJJ, Gerald C, and Brancheck TA. Cloned galanin receptors: pharmacology of GalR1 and GalR2 receptor subtypes (Abstract). Soc Neurosci Abstr 23: 962, 1997.
41. Wang S, He C, Maguire T, Clemmons AL, Burrier RE, Guzzi MF, Strader CD, Parker EM, and Bayne ML. Genomic organization and functional regulation of the mouse GalR1 galanin receptor. FEBS Lett 411: 225-230, 1997.
42. Wang YF, Mao YK, McDonald TJ, and Daniel EE. Distribution of galanin-immunoreactive nerves in the canine gastrointestinal tract. Peptides 16: 237-247, 1995.
43. Waynforth HB and Flecknell PA. Experimental and Surgical Technique in the Rat. San Diego, CA: Academic, 1992, p. 1-372.
44. Wissink S, van Heerde EC, vand der Burg B, and van der Saag PT. A dual mechanism mediates repression of NF-κB activity by glucocorticoids. Mol Endocrinol 12: 355-363, 1998.
45. Yu J, Harden DG, Pitler TA, and Gallager DW. Agonist properties of chimeric galanin peptides (Abstract). Soc Neurosci 23: 393, 1997.
46. Zunjic M, Savkovic SD, Koutsouris A, and Hecht G. Increased IL-8 expression induced by Salmonella, as compared to pathogenic E. coli, results from synergism between NF-κB and NF-IL6 (Abstract). Gastroenterology 112: A1128, 1997.