메뉴 건너뛰기




Volumn 12, Issue , 2012, Pages

Protective role of 1,25(OH)2vitamin D3 in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice

Author keywords

1,25 dihydroxyvitamin D3; Barrier protection function; Dextran sulfate sodium; Inflammatory bowel disease; Tight junction

Indexed keywords

CALCITRIOL; CYTOKINE; DEXTRAN SULFATE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; MESSENGER RNA; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84861540381     PISSN: None     EISSN: 1471230X     Source Type: Journal    
DOI: 10.1186/1471-230X-12-57     Document Type: Article
Times cited : (239)

References (45)
  • 1
    • 77957356424 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma 2 mutation may cause a subset of ulcerative colitis
    • 10.1111/j.1442-200X.2010.03195.x, 20591056
    • Aoyagi Y, Nagata S, Kudo T, Fujii T, Wada M, Chiba Y, Ohtsuka Y, Yamashiro Y, Shimizu T, Ohkusa T. Peroxisome proliferator-activated receptor gamma 2 mutation may cause a subset of ulcerative colitis. Pediatr Int 2010, 52:729-734. 10.1111/j.1442-200X.2010.03195.x, 20591056.
    • (2010) Pediatr Int , vol.52 , pp. 729-734
    • Aoyagi, Y.1    Nagata, S.2    Kudo, T.3    Fujii, T.4    Wada, M.5    Chiba, Y.6    Ohtsuka, Y.7    Yamashiro, Y.8    Shimizu, T.9    Ohkusa, T.10
  • 2
    • 79851479595 scopus 로고    scopus 로고
    • Immunopathogenesis of inflammatory bowel disease
    • 3062384, 21487504
    • Matricon J, Barnich N, Ardid D. Immunopathogenesis of inflammatory bowel disease. Self Nonself 2010, 1:299-309. 3062384, 21487504.
    • (2010) Self Nonself , vol.1 , pp. 299-309
    • Matricon, J.1    Barnich, N.2    Ardid, D.3
  • 3
    • 9344257937 scopus 로고    scopus 로고
    • Increased gut permeability in Crohn's disease: is TNF the link?
    • 10.1136/gut.2004.047092, 1774337, 15542502
    • Gibson PR. Increased gut permeability in Crohn's disease: is TNF the link?. Gut 2004, 53:1724-1725. 10.1136/gut.2004.047092, 1774337, 15542502.
    • (2004) Gut , vol.53 , pp. 1724-1725
    • Gibson, P.R.1
  • 4
    • 61949313980 scopus 로고    scopus 로고
    • Intestinal barrier dysfunction in inflammatory bowel diseases
    • 10.1002/ibd.20539, 18623167
    • McGuckin MA, Eri R, Simms LA, Florin TH, Radford-Smith G. Intestinal barrier dysfunction in inflammatory bowel diseases. Inflamm Bowel Dis 2009, 15:100-113. 10.1002/ibd.20539, 18623167.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 100-113
    • McGuckin, M.A.1    Eri, R.2    Simms, L.A.3    Florin, T.H.4    Radford-Smith, G.5
  • 5
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • 10.1038/nri2653, 19855405
    • Turner JR. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 2009, 9:799-809. 10.1038/nri2653, 19855405.
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 6
    • 70449505391 scopus 로고    scopus 로고
    • Therapeutic options to modulate barrier defects in inflammatory bowel disease
    • 10.1159/000233283, 19897959
    • Hering NA, Schulzke JD. Therapeutic options to modulate barrier defects in inflammatory bowel disease. Dig Dis 2009, 27:450-454. 10.1159/000233283, 19897959.
    • (2009) Dig Dis , vol.27 , pp. 450-454
    • Hering, N.A.1    Schulzke, J.D.2
  • 7
    • 67249099003 scopus 로고    scopus 로고
    • Dynamic regulation of epithelial cell fate and barrier function by intercellular junctions
    • 10.1111/j.1749-6632.2009.04025.x, 19538310
    • Koch S, Nusrat A. Dynamic regulation of epithelial cell fate and barrier function by intercellular junctions. Ann N Y Acad Sci 2009, 1165:220-227. 10.1111/j.1749-6632.2009.04025.x, 19538310.
    • (2009) Ann N Y Acad Sci , vol.1165 , pp. 220-227
    • Koch, S.1    Nusrat, A.2
  • 8
    • 67650511409 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase mediates disassembly of apical junctions in model intestinal epithelia
    • 10.4161/cc.8.13.8928, 19502798
    • Naydenov NG, Hopkins AM, Ivanov AI. c-Jun N-terminal kinase mediates disassembly of apical junctions in model intestinal epithelia. Cell Cycle 2009, 8:2110-2121. 10.4161/cc.8.13.8928, 19502798.
    • (2009) Cell Cycle , vol.8 , pp. 2110-2121
    • Naydenov, N.G.1    Hopkins, A.M.2    Ivanov, A.I.3
  • 9
    • 52049094403 scopus 로고    scopus 로고
    • Oxidative stress induces gastric epithelial permeability through claudin-3
    • 10.1016/j.bbrc.2008.08.140, 18774778
    • Hashimoto K, Oshima T, Tomita T, Kim Y, Matsumoto T, Joh T, Miwa H. Oxidative stress induces gastric epithelial permeability through claudin-3. Biochem Biophys Res Commun 2008, 376:154-157. 10.1016/j.bbrc.2008.08.140, 18774778.
    • (2008) Biochem Biophys Res Commun , vol.376 , pp. 154-157
    • Hashimoto, K.1    Oshima, T.2    Tomita, T.3    Kim, Y.4    Matsumoto, T.5    Joh, T.6    Miwa, H.7
  • 10
    • 78650174720 scopus 로고    scopus 로고
    • Mycotoxin deoxynivalenol (DON) mediates biphasic cellular response in intestinal porcine epithelial cell lines IPEC-1 and IPEC-J2
    • 10.1016/j.toxlet.2010.10.006, 20937367
    • Diesing AK, Nossol C, Panther P, Walk N, Post A, Kluess J, Kreutzmann P, Danicke S, Rothkotter HJ, Kahlert S. Mycotoxin deoxynivalenol (DON) mediates biphasic cellular response in intestinal porcine epithelial cell lines IPEC-1 and IPEC-J2. Toxicol Lett 2011, 200:8-18. 10.1016/j.toxlet.2010.10.006, 20937367.
    • (2011) Toxicol Lett , vol.200 , pp. 8-18
    • Diesing, A.K.1    Nossol, C.2    Panther, P.3    Walk, N.4    Post, A.5    Kluess, J.6    Kreutzmann, P.7    Danicke, S.8    Rothkotter, H.J.9    Kahlert, S.10
  • 12
    • 77954217700 scopus 로고    scopus 로고
    • Glycogen Synthase Kinase 3 (GSK-3) influences epithelial barrier function by regulating occludin, claudin-1 and E-cadherin expression
    • 10.1016/j.bbrc.2010.05.164, 2974955, 20617560
    • Severson EA, Kwon M, Hilgarth RS, Parkos CA, Nusrat A. Glycogen Synthase Kinase 3 (GSK-3) influences epithelial barrier function by regulating occludin, claudin-1 and E-cadherin expression. Biochem Biophys Res Commun 2010, 397:592-597. 10.1016/j.bbrc.2010.05.164, 2974955, 20617560.
    • (2010) Biochem Biophys Res Commun , vol.397 , pp. 592-597
    • Severson, E.A.1    Kwon, M.2    Hilgarth, R.S.3    Parkos, C.A.4    Nusrat, A.5
  • 13
    • 58149237750 scopus 로고    scopus 로고
    • Epithelial function in eosinophilic gastrointestinal diseases
    • 10.1016/j.iac.2008.09.003, 19141352
    • Fillon S, Robinson ZD, Colgan SP, Furuta GT. Epithelial function in eosinophilic gastrointestinal diseases. Immunol Allergy Clin North Am 2009, 29:171-178. 10.1016/j.iac.2008.09.003, 19141352.
    • (2009) Immunol Allergy Clin North Am , vol.29 , pp. 171-178
    • Fillon, S.1    Robinson, Z.D.2    Colgan, S.P.3    Furuta, G.T.4
  • 14
    • 44349083637 scopus 로고    scopus 로고
    • In vivo gene expression profiling of human intestinal epithelial cells: analysis by laser microdissection of formalin fixed tissues
    • 10.1186/1471-2164-9-209, 2394537, 18457593
    • George MD, Wehkamp J, Kays RJ, Leutenegger CM, Sabir S, Grishina I, Dandekar S, Bevins CL. In vivo gene expression profiling of human intestinal epithelial cells: analysis by laser microdissection of formalin fixed tissues. BMC Genomics 2008, 9:209. 10.1186/1471-2164-9-209, 2394537, 18457593.
    • (2008) BMC Genomics , vol.9 , pp. 209
    • George, M.D.1    Wehkamp, J.2    Kays, R.J.3    Leutenegger, C.M.4    Sabir, S.5    Grishina, I.6    Dandekar, S.7    Bevins, C.L.8
  • 15
    • 75349108490 scopus 로고    scopus 로고
    • Probiotic-induced changes in the intestinal epithelium: implications in gastrointestinal disease
    • Ramakrishna BS. Probiotic-induced changes in the intestinal epithelium: implications in gastrointestinal disease. Trop Gastroenterol 2009, 30:76-85.
    • (2009) Trop Gastroenterol , vol.30 , pp. 76-85
    • Ramakrishna, B.S.1
  • 16
    • 77954403643 scopus 로고    scopus 로고
    • Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease
    • 10.1016/j.imlet.2010.03.006, 20350569
    • Laverny G, Penna G, Vetrano S, Correale C, Nebuloni M, Danese S, Adorini L. Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease. Immunol Lett 2010, 131:49-58. 10.1016/j.imlet.2010.03.006, 20350569.
    • (2010) Immunol Lett , vol.131 , pp. 49-58
    • Laverny, G.1    Penna, G.2    Vetrano, S.3    Correale, C.4    Nebuloni, M.5    Danese, S.6    Adorini, L.7
  • 17
    • 79960719546 scopus 로고    scopus 로고
    • Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling
    • 10.1093/intimm/dxr045, 3139478, 21697289
    • Bruce D, Yu S, Ooi JH, Cantorna MT. Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling. Int Immunol 2011, 23:519-528. 10.1093/intimm/dxr045, 3139478, 21697289.
    • (2011) Int Immunol , vol.23 , pp. 519-528
    • Bruce, D.1    Yu, S.2    Ooi, J.H.3    Cantorna, M.T.4
  • 20
    • 77949873898 scopus 로고    scopus 로고
    • Vitamin D controls T cell antigen receptor signaling and activation of human T cells
    • 10.1038/ni.1851, 20208539
    • von Essen MR, Kongsbak M, Schjerling P, Olgaard K, Odum N, Geisler C. Vitamin D controls T cell antigen receptor signaling and activation of human T cells. Nat Immunol 2010, 11:344-349. 10.1038/ni.1851, 20208539.
    • (2010) Nat Immunol , vol.11 , pp. 344-349
    • von Essen, M.R.1    Kongsbak, M.2    Schjerling, P.3    Olgaard, K.4    Odum, N.5    Geisler, C.6
  • 21
    • 77958485853 scopus 로고    scopus 로고
    • Vitamin D and mucosal immune function
    • 10.1097/MOG.0b013e32833d4b9f, 2955835, 20639756
    • Sun J. Vitamin D and mucosal immune function. Curr Opin Gastroenterol 2010, 26:591-595. 10.1097/MOG.0b013e32833d4b9f, 2955835, 20639756.
    • (2010) Curr Opin Gastroenterol , vol.26 , pp. 591-595
    • Sun, J.1
  • 22
    • 34247282706 scopus 로고    scopus 로고
    • Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury
    • 10.1186/1471-2172-8-5, 1852118, 17397543
    • Froicu M, Cantorna MT. Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury. BMC Immunol 2007, 8:5. 10.1186/1471-2172-8-5, 1852118, 17397543.
    • (2007) BMC Immunol , vol.8 , pp. 5
    • Froicu, M.1    Cantorna, M.T.2
  • 23
    • 0346219142 scopus 로고    scopus 로고
    • A crucial role for the vitamin D receptor in experimental inflammatory bowel diseases
    • 10.1210/me.2003-0281, 14500760
    • Froicu M, Weaver V, Wynn TA, McDowell MA, Welsh JE, Cantorna MT. A crucial role for the vitamin D receptor in experimental inflammatory bowel diseases. Mol Endocrinol 2003, 17:2386-2392. 10.1210/me.2003-0281, 14500760.
    • (2003) Mol Endocrinol , vol.17 , pp. 2386-2392
    • Froicu, M.1    Weaver, V.2    Wynn, T.A.3    McDowell, M.A.4    Welsh, J.E.5    Cantorna, M.T.6
  • 24
    • 77954562871 scopus 로고    scopus 로고
    • Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity
    • 10.1007/s00109-010-0590-9, 2861286, 20119827
    • Kamen DL, Tangpricha V. Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity. J Mol Med 2010, 88:441-450. 10.1007/s00109-010-0590-9, 2861286, 20119827.
    • (2010) J Mol Med , vol.88 , pp. 441-450
    • Kamen, D.L.1    Tangpricha, V.2
  • 25
    • 77957373318 scopus 로고    scopus 로고
    • Mechanisms underlying the effect of vitamin D on the immune system
    • 10.1017/S0029665110001722, 3138329, 20515520
    • Cantorna MT. Mechanisms underlying the effect of vitamin D on the immune system. Proc Nutr Soc 2010, 69:286-289. 10.1017/S0029665110001722, 3138329, 20515520.
    • (2010) Proc Nutr Soc , vol.69 , pp. 286-289
    • Cantorna, M.T.1
  • 26
    • 76149131666 scopus 로고    scopus 로고
    • Update in vitamin D
    • 10.1210/jc.2009-1773, 2840860, 20133466
    • Adams JS, Hewison M. Update in vitamin D. J Clin Endocrinol Metab 2010, 95:471-478. 10.1210/jc.2009-1773, 2840860, 20133466.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 471-478
    • Adams, J.S.1    Hewison, M.2
  • 27
    • 29844438189 scopus 로고    scopus 로고
    • UVR, vitamin D and three autoimmune diseases--multiple sclerosis, type 1 diabetes, rheumatoid arthritis
    • 10.1562/2005-02-15-IR-441, 15971932
    • Onsonby AL, Lucas RM, van der Mei IA. UVR, vitamin D and three autoimmune diseases--multiple sclerosis, type 1 diabetes, rheumatoid arthritis. Photochem Photobiol 2005, 81:1267-1275. 10.1562/2005-02-15-IR-441, 15971932.
    • (2005) Photochem Photobiol , vol.81 , pp. 1267-1275
    • Onsonby, A.L.1    Lucas, R.M.2    van der Mei, I.A.3
  • 28
    • 0037534426 scopus 로고    scopus 로고
    • Vitamin D receptor genotypes are not associated with rheumatoid arthritis or biochemical parameters of bone turnover in German RA patients
    • Goertz B, Fassbender WJ, Williams JC, Marzeion AM, Bretzel RG, Stracke H, Berliner MN. Vitamin D receptor genotypes are not associated with rheumatoid arthritis or biochemical parameters of bone turnover in German RA patients. Clin Exp Rheumatol 2003, 21:333-339.
    • (2003) Clin Exp Rheumatol , vol.21 , pp. 333-339
    • Goertz, B.1    Fassbender, W.J.2    Williams, J.C.3    Marzeion, A.M.4    Bretzel, R.G.5    Stracke, H.6    Berliner, M.N.7
  • 29
    • 0033745125 scopus 로고    scopus 로고
    • 1,25-Dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease
    • Cantorna MT, Munsick C, Bemiss C, Mahon BD. 1,25-Dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease. J Nutr 2000, 130:2648-2652.
    • (2000) J Nutr , vol.130 , pp. 2648-2652
    • Cantorna, M.T.1    Munsick, C.2    Bemiss, C.3    Mahon, B.D.4
  • 30
    • 0027224059 scopus 로고
    • Clinicopathologic study of dextran sulfate sodium experimental murine colitis
    • Cooper HS, Murthy SN, Shah RS, Sedergran DJ. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 1993, 69:238-249.
    • (1993) Lab Invest , vol.69 , pp. 238-249
    • Cooper, H.S.1    Murthy, S.N.2    Shah, R.S.3    Sedergran, D.J.4
  • 31
    • 45449106153 scopus 로고    scopus 로고
    • The role of estrogen receptor subtypes on hepatic neutrophil accumulation following trauma-hemorrhage: direct modulation of CINC-1 production by Kupffer cells
    • 10.1016/j.cyto.2008.04.001, 2542505, 18468914
    • Shimizu T, Suzuki T, Yu HP, Yokoyama Y, Choudhry MA, Bland KI, Chaudry IH. The role of estrogen receptor subtypes on hepatic neutrophil accumulation following trauma-hemorrhage: direct modulation of CINC-1 production by Kupffer cells. Cytokine 2008, 43:88-92. 10.1016/j.cyto.2008.04.001, 2542505, 18468914.
    • (2008) Cytokine , vol.43 , pp. 88-92
    • Shimizu, T.1    Suzuki, T.2    Yu, H.P.3    Yokoyama, Y.4    Choudhry, M.A.5    Bland, K.I.6    Chaudry, I.H.7
  • 32
    • 65549088539 scopus 로고    scopus 로고
    • Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice
    • 10.1093/toxsci/kfp057, 19293371
    • Nygaard UC, Hansen JS, Samuelsen M, Alberg T, Marioara CD, Løvik M. Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice. Toxicol Sci 2009, 109:113-123. 10.1093/toxsci/kfp057, 19293371.
    • (2009) Toxicol Sci , vol.109 , pp. 113-123
    • Nygaard, U.C.1    Hansen, J.S.2    Samuelsen, M.3    Alberg, T.4    Marioara, C.D.5    Løvik, M.6
  • 34
    • 0024451174 scopus 로고
    • Exchange of macromolecules between plasma and peritoneal cavity in ascites tumor-bearing, normal, and serotonin-injected mice
    • Nagy JA, Herzberg KT, Masse EM, Zientara GP, Dvorak HF. Exchange of macromolecules between plasma and peritoneal cavity in ascites tumor-bearing, normal, and serotonin-injected mice. Cancer Res 1989, 49:5448-5458.
    • (1989) Cancer Res , vol.49 , pp. 5448-5458
    • Nagy, J.A.1    Herzberg, K.T.2    Masse, E.M.3    Zientara, G.P.4    Dvorak, H.F.5
  • 35
    • 0029043175 scopus 로고
    • High precision measurement of electrical resistance across endothelial cell monolayers
    • 10.1007/BF00373850, 7667075
    • Tschugguel W, Zhegu Z, Gajdzik L, Maier M, Binder BR, Graf J. High precision measurement of electrical resistance across endothelial cell monolayers. Pflugers Arch 1995, 430:145-147. 10.1007/BF00373850, 7667075.
    • (1995) Pflugers Arch , vol.430 , pp. 145-147
    • Tschugguel, W.1    Zhegu, Z.2    Gajdzik, L.3    Maier, M.4    Binder, B.R.5    Graf, J.6
  • 36
    • 77649313855 scopus 로고    scopus 로고
    • Protection of intestinal occludin tight junction protein by dietary gangliosides in lipopolysaccharide-induced acute inflammation
    • 10.1097/MPG.0b013e3181ae2ba0, 20118807
    • Park EJ, Thomson AB, Clandinin MT. Protection of intestinal occludin tight junction protein by dietary gangliosides in lipopolysaccharide-induced acute inflammation. J Pediatr Gastroenterol Nutr 2010, 50:321-328. 10.1097/MPG.0b013e3181ae2ba0, 20118807.
    • (2010) J Pediatr Gastroenterol Nutr , vol.50 , pp. 321-328
    • Park, E.J.1    Thomson, A.B.2    Clandinin, M.T.3
  • 37
    • 77957872537 scopus 로고    scopus 로고
    • Role of mast cells in inflammatory bowel disease and inflammation-associated colorectal neoplasia in IL-10-deficient mice
    • Chichlowski M, Westwood GS, Abraham SN, Hale LP. Role of mast cells in inflammatory bowel disease and inflammation-associated colorectal neoplasia in IL-10-deficient mice. PLoS One 2010, 17:e12220.
    • (2010) PLoS One , vol.17
    • Chichlowski, M.1    Westwood, G.S.2    Abraham, S.N.3    Hale, L.P.4
  • 38
    • 70350029623 scopus 로고    scopus 로고
    • Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization
    • 10.1016/j.taap.2009.08.002, 2877281, 19679145
    • McCall IC, Betanzos A, Weber DA, Nava P, Miller GW, Parkos CA. Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization. Toxicol Appl Pharmacol 2009, 241:61-70. 10.1016/j.taap.2009.08.002, 2877281, 19679145.
    • (2009) Toxicol Appl Pharmacol , vol.241 , pp. 61-70
    • McCall, I.C.1    Betanzos, A.2    Weber, D.A.3    Nava, P.4    Miller, G.W.5    Parkos, C.A.6
  • 39
    • 80052400212 scopus 로고    scopus 로고
    • IL-6 regulates claudin-2 expression and tight junction permeability in intestinal epithelium
    • Jul 19 M111.238147
    • Suzuki T, Yoshinaga N, Tanabe S. IL-6 regulates claudin-2 expression and tight junction permeability in intestinal epithelium. J Biol Chem 2011, Jul 19 M111.238147.
    • (2011) J Biol Chem
    • Suzuki, T.1    Yoshinaga, N.2    Tanabe, S.3
  • 41
    • 78049468823 scopus 로고    scopus 로고
    • MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function
    • 10.1053/j.gastro.2010.07.040, 3156097, 20659473
    • McKenna LB, Schug J, Vourekas A, McKenna JB, Bramswig NC, Friedman JR, Kaestner KH. MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function. Gastroenterology 2010, 139:1654-1664. 10.1053/j.gastro.2010.07.040, 3156097, 20659473.
    • (2010) Gastroenterology , vol.139 , pp. 1654-1664
    • McKenna, L.B.1    Schug, J.2    Vourekas, A.3    McKenna, J.B.4    Bramswig, N.C.5    Friedman, J.R.6    Kaestner, K.H.7
  • 44
    • 19644372625 scopus 로고    scopus 로고
    • Dislocation of tight junction proteins without F-actin disruption in inactive Crohn's disease
    • Oshitani N, Watanabe K, Nakamura S, Fujiwara Y, Higuchi K, Arakawa T. Dislocation of tight junction proteins without F-actin disruption in inactive Crohn's disease. Int J Mol Med 2005, 15:407-410.
    • (2005) Int J Mol Med , vol.15 , pp. 407-410
    • Oshitani, N.1    Watanabe, K.2    Nakamura, S.3    Fujiwara, Y.4    Higuchi, K.5    Arakawa, T.6
  • 45
    • 65349193040 scopus 로고    scopus 로고
    • L. plantarum prevents enteroinvasive Escherichia coli-induced tight junction proteins changes in intestinal epithelial cells
    • 10.1186/1471-2180-9-63, 2674056, 19331693
    • Qin H, Zhang Z, Hang X, Jiang Y. L. plantarum prevents enteroinvasive Escherichia coli-induced tight junction proteins changes in intestinal epithelial cells. BMC Microbiol 2009, 9:63. 10.1186/1471-2180-9-63, 2674056, 19331693.
    • (2009) BMC Microbiol , vol.9 , pp. 63
    • Qin, H.1    Zhang, Z.2    Hang, X.3    Jiang, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.