Targeted colonic claudin-2 expression renders resistance to epithelial injury, induces immune suppression, and protects from colitis

Mucosal Immunology

Volumn 7, Issue 6, 2014, Pages 1340-1353

  Ahmad, R ^a   Chaturvedi, R ^a   Olivares Villagomez D ^a   Habib, T ^b   Asim, M ^a   Shivesh, P ^c   Polk, D B ^c   Wilson, K T ^a,d   Washington, M K ^a   Van Kaer, L ^a   Dhawan, P ^a,d,e   Singh, A B ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b Badger Technical Services   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Affairs Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; TRANSFORMING GROWTH FACTOR BETA; CLAUDIN; CLDN2 PROTEIN, HUMAN; CLDN2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ FOXP+ T LYMPHOCYTE; CELL DAMAGE; CELL DEATH; CELL ISOLATION; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; COLITIS; COLON MUCOSA; CONTROLLED STUDY; EPITHELIUM CELL; EXPERIMENTAL COLITIS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; INTESTINE MUCOSA PERMEABILITY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; ANIMAL; CACO 2 CELL LINE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INJURIES; INNATE IMMUNITY; INTESTINE MUCOSA; MUCOSAL IMMUNITY; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; CACO-2 CELLS; CLAUDINS; COLITIS; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; MICE; MICE, TRANSGENIC; T-LYMPHOCYTES, REGULATORY;

EID: 84908181172     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2014.21     Document Type: Article

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