Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

eLife

Volumn 5, Issue NOVEMBER2016, 2016, Pages

  Ma, Siming ^a   Upneja, Akhil ^a   Galecki, Andrzej ^b,c   Tsai, Yi Miau ^b   Burant, Charles F ^b   Raskind, Sasha ^b   Zhang, Quanwei ^d   Zhang, Zhengdong D ^d   Seluanov, Andrei ^e   Gorbunova, Vera ^e   Clish, Clary B ^f   Miller, Richard A ^b   Gladyshev, Vadim N ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF ROCHESTER   (United States)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR JUND;

ADULT; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DAMAGE; CONTROLLED STUDY; DNA REPAIR; FEMALE; GENE EXPRESSION; GENETIC VARIATION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; IONIZATION; LONGEVITY; MAMMAL; METABOLIC REGULATION; METABOLIC STRESS; MOLECULAR PHYLOGENY; NONHUMAN; OXIDATIVE STRESS; PRIMATE; PROTEIN DEGRADATION; PROTEIN TRANSPORT; RNA SEQUENCE; SKIN FIBROBLAST; SPECIES; UBIQUITINATION; UPREGULATION; ANIMAL; BIRD; CELL CULTURE TECHNIQUE; COMPARATIVE STUDY; ENERGY METABOLISM; FIBROBLAST; GENE EXPRESSION PROFILING; METABOLOMICS; PHYSIOLOGY;

ANIMALS; BIRDS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; DNA REPAIR; ENERGY METABOLISM; FIBROBLASTS; GENE EXPRESSION PROFILING; LONGEVITY; MAMMALS; METABOLOMICS;

EID: 85006069979     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.19130     Document Type: Article

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