Human longevity and variation in DNA damage response and repair: Study of the contribution of sub-processes using competitive gene-set analysis

European Journal of Human Genetics

Volumn 22, Issue 9, 2014, Pages 1131-1136

  Debrabant, Birgit ^a   Soerensen, Mette ^a,b   Flachsbart, Friederike ^c   Dato, Serena ^d   Mengel From, Jonas ^a,b   Stevnsner, Tinna ^e   Bohr, Vilhelm A ^e,f   Kruse, Torben A ^b   Schreiber, Stefan ^c   Nebel, Almut ^c   Christensen, Kaare ^a,b   Tan, Qihua ^a,b   Christiansen, Lene ^a,b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

^c UNIVERSITY OF KIEL   (Germany)

^d UNIVERSITY OF CALABRIA   (Italy)

^e AARHUS UNIVERSITY   (Denmark)

^f NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

case control data; competitive gene set analysis; DNA damage response and DNA repair; human longevity; SNPs

Indexed keywords

DNA; MITOCHONDRIAL DNA; RECQ HELICASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE;

ADULT; AGED; ARTICLE; COMPETITIVE GENE SET ANALYSIS; CONTROLLED STUDY; DNA DAMAGE; DNA END JOINING REPAIR; DNA REPAIR; ENZYME ACTIVITY; EXCISION REPAIR; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HUMAN; LONGEVITY; MALE; MIDDLE AGED; MISMATCH REPAIR; PRIORITY JOURNAL; RECOMBINATION REPAIR; REPLICATION STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; TELOMERE; CASE CONTROL STUDY; GENETICS; VERY ELDERLY; DANE (PEOPLE); GERMAN (CITIZEN); MAJOR CLINICAL STUDY;

AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; DNA DAMAGE; DNA REPAIR; DNA REPAIR ENZYMES; FEMALE; HUMANS; LONGEVITY; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84906255444     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2013.299     Document Type: Article

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