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Volumn 144, Issue 3, 2015, Pages 352-364

Endocannabinoid signalling in innate and adaptive immunity

Author keywords

Cell signalling; Endocannabinoids; Immune cells

Indexed keywords

ENDOCANNABINOID;

EID: 85003550846     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12441     Document Type: Review
Times cited : (121)

References (137)
  • 1
    • 0029031421 scopus 로고
    • Anandamide, an endogenous cannabinomimetic eicosanoid ’killing two birds with one stone’
    • Di Marzo V, Fontana A. Anandamide, an endogenous cannabinomimetic eicosanoid:’killing two birds with one stone’. Prostaglandins Leukot Essent Fatty Acids 1995; 53:1-11.
    • (1995) Prostaglandins Leukot Essent Fatty Acids , vol.53 , pp. 1-11
    • Di Marzo, V.1    Fontana, A.2
  • 3
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane WA, Hannus L, Breuer A et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992; 258:1946-9.
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hannus, L.2    Breuer, A.3
  • 4
    • 0029012014 scopus 로고
    • Identification of an endogenous 2-mono-glyceride, present in canine gut, that binds to cannabinoid receptors
    • Mechoulam R, Ben-Shabat S, Hanus L et al. Identification of an endogenous 2-mono-glyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 1995; 50:83-90.
    • (1995) Biochem Pharmacol , vol.50 , pp. 83-90
    • Mechoulam, R.1    Ben-Shabat, S.2    Hanus, L.3
  • 6
  • 8
    • 56449095685 scopus 로고    scopus 로고
    • Role of endocannabinoids and their analogues in obesity and eating disorders
    • Gaetani S, Kaye WH, Cuomo V, Piomelli D. Role of endocannabinoids and their analogues in obesity and eating disorders. Eat Weight Disord 2008; 13:e42-6.
    • (2008) Eat Weight Disord , vol.13
    • Gaetani, S.1    Kaye, W.H.2    Cuomo, V.3    Piomelli, D.4
  • 10
    • 67649470418 scopus 로고    scopus 로고
    • Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins
    • Oddi S, Fezza F, Pasquariello N et al. Molecular identification of albumin and Hsp70 as cytosolic anandamide-binding proteins. Chem Biol 2009; 16:624-32.
    • (2009) Chem Biol , vol.16 , pp. 624-632
    • Oddi, S.1    Fezza, F.2    Pasquariello, N.3
  • 11
    • 77449131626 scopus 로고    scopus 로고
    • Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2
    • Kaczocha M, Glaser ST, Chae J, Brown DA, Deutsch DG. Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2. J Biol Chem 2010; 285:2796-806.
    • (2010) J Biol Chem , vol.285 , pp. 2796-2806
    • Kaczocha, M.1    Glaser, S.T.2    Chae, J.3    Brown, D.A.4    Deutsch, D.G.5
  • 12
    • 78049232267 scopus 로고    scopus 로고
    • Intracellular trafficking of anandamide: New concepts for signaling
    • Maccarrone M, Dainese E, Oddi S. Intracellular trafficking of anandamide: new concepts for signaling. Trends Biochem Sci 2010; 35:601-8.
    • (2010) Trends Biochem Sci , vol.35 , pp. 601-608
    • Maccarrone, M.1    Dainese, E.2    Oddi, S.3
  • 13
    • 84876951107 scopus 로고    scopus 로고
    • Metabolism of endocannabinoids and related N-acylethanolamines: Canonical and alternative pathways
    • Ueda N, Tsuboi K, Uyama T. Metabolism of endocannabinoids and related N-acylethanolamines: canonical and alternative pathways. FEBS J 2013; 9:1874-94.
    • (2013) FEBS J , vol.9 , pp. 1874-1894
    • Ueda, N.1    Tsuboi, K.2    Uyama, T.3
  • 14
    • 1242294480 scopus 로고    scopus 로고
    • Molecular characterization of a phospholipase D generating anandamide and its congeners
    • Okamoto Y, Morishita J, Tsuboi K, Tonai T, Ueda N. Molecular characterization of a phospholipase D generating anandamide and its congeners. J Biol Chem 2004; 279:5298-305.
    • (2004) J Biol Chem , vol.279 , pp. 5298-5305
    • Okamoto, Y.1    Morishita, J.2    Tsuboi, K.3    Tonai, T.4    Ueda, N.5
  • 15
    • 3042737612 scopus 로고    scopus 로고
    • Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D
    • Sun YX, Tsuboi K, Okamoto Y, Tonai T, Murakami M, Kudo I, Ueda N. Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D. Biochem J 2004; 380:749-56.
    • (2004) Biochem J , vol.380 , pp. 749-756
    • Sun, Y.X.1    Tsuboi, K.2    Okamoto, Y.3    Tonai, T.4    Murakami, M.5    Kudo, I.6    Ueda, N.7
  • 16
    • 77954582423 scopus 로고    scopus 로고
    • Characterization of mice lacking candidate N-acyl ethanol-amine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo
    • Simon GM, Cravatt BF. Characterization of mice lacking candidate N-acyl ethanol-amine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo. Mol BioSyst 2010; 6:1411-8.
    • (2010) Mol Biosyst , vol.6 , pp. 1411-1418
    • Simon, G.M.1    Cravatt, B.F.2
  • 18
    • 10744229235 scopus 로고    scopus 로고
    • Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain
    • Bisogno T, Howell F, Williams G et al. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J Cell Biol 2003; 163:463-8.
    • (2003) J Cell Biol , vol.163 , pp. 463-468
    • Bisogno, T.1    Howell, F.2    Williams, G.3
  • 19
    • 0036612968 scopus 로고    scopus 로고
    • 2-Arachido-noyl-sn-glycero-3-phosphate, an arachidonic acid-containing lysophosphatidic acid: Occurrence and rapid enzymatic conversion to 2-arachidonoyl-sn-glycerol, a cannabinoid receptor ligand, in rat brain
    • Nakane S, Oka S, Arai S, Waku K, Ishima Y, Tokumura A, Sugiura T. 2-Arachido-noyl-sn-glycero-3-phosphate, an arachidonic acid-containing lysophosphatidic acid: occurrence and rapid enzymatic conversion to 2-arachidonoyl-sn-glycerol, a cannabinoid receptor ligand, in rat brain. Arch Biochem Biophys 2002; 402:51-8.
    • (2002) Arch Biochem Biophys , vol.402 , pp. 51-58
    • Nakane, S.1    Oka, S.2    Arai, S.3    Waku, K.4    Ishima, Y.5    Tokumura, A.6    Sugiura, T.7
  • 20
    • 22244484464 scopus 로고    scopus 로고
    • Structure and function of fatty acid amide hydrolase
    • McKinney MK, Cravatt BF. Structure and function of fatty acid amide hydrolase. Annu Rev Biochem 2005; 74:411-32.
    • (2005) Annu Rev Biochem , vol.74 , pp. 411-432
    • McKinney, M.K.1    Cravatt, B.F.2
  • 21
    • 37149013708 scopus 로고    scopus 로고
    • A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
    • Blankman JL, Simon GM, Cravatt BF. A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. Chem Biol 2007; 14:1347-56.
    • (2007) Chem Biol , vol.14 , pp. 1347-1356
    • Blankman, J.L.1    Simon, G.M.2    Cravatt, B.F.3
  • 22
    • 77955053537 scopus 로고    scopus 로고
    • The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
    • Marrs WR, Blankman JL, Horne EA et al. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nat Neurosci 2010; 13:951-7.
    • (2010) Nat Neurosci , vol.13 , pp. 951-957
    • Marrs, W.R.1    Blankman, J.L.2    Horne, E.A.3
  • 23
    • 78650120798 scopus 로고    scopus 로고
    • International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: Beyond CB1 and CB2
    • Pertwee RG, Howlett AC, Abood ME et al. International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2. Pharmacol Rev 2010; 62:588-631.
    • (2010) Pharmacol Rev , vol.62 , pp. 588-631
    • Pertwee, R.G.1    Howlett, A.C.2    Abood, M.E.3
  • 24
    • 80053571291 scopus 로고    scopus 로고
    • Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease
    • Basu S, Dittel BN. Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease. Immunol Res 2011; 51:26-38.
    • (2011) Immunol Res , vol.51 , pp. 26-38
    • Basu, S.1    Dittel, B.N.2
  • 25
    • 26844504226 scopus 로고    scopus 로고
    • Identification and functional characterization of brainstem cannabinoid CB2 receptors
    • Van Sickle MD, Duncan M, Kingsley PJ et al. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 2005; 310:329-32
    • (2005) Science , vol.310 , pp. 329-332
    • Van Sickle, M.D.1    Duncan, M.2    Kingsley, P.J.3
  • 26
    • 33749544716 scopus 로고    scopus 로고
    • Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain
    • Onaivi ES, Ishiguro H, Gong JP et al. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Ann N Y Acad Sci 2006; 1074:514-36.
    • (2006) Ann N Y Acad Sci , vol.1074 , pp. 514-536
    • Onaivi, E.S.1    Ishiguro, H.2    Gong, J.P.3
  • 27
    • 77952623444 scopus 로고    scopus 로고
    • CB2: A cannabinoid receptor with an identity crisis
    • Atwood BK, Mackie K. CB2: a cannabinoid receptor with an identity crisis. Br J Pharmacol 2010; 3:467-79.
    • (2010) Br J Pharmacol , vol.3 , pp. 467-479
    • Atwood, B.K.1    Mackie, K.2
  • 30
    • 77950660113 scopus 로고    scopus 로고
    • Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs
    • Di Marzo V, De Petrocellis L. Endocannabinoids as regulators of transient receptor potential (TRP) channels: a further opportunity to develop new endocannabinoid-based therapeutic drugs. Curr Med Chem 2010; 17:1430-49.
    • (2010) Curr Med Chem , vol.17 , pp. 1430-1449
    • Di Marzo, V.1    De Petrocellis, L.2
  • 31
    • 84891599659 scopus 로고    scopus 로고
    • Monoacylglycerols activate TRPV1 – a link between phospholipase C and TRPV1
    • Zygmunt PM, Ermund A, Movahed P et al. Monoacylglycerols activate TRPV1 – a link between phospholipase C and TRPV1. PLoS ONE 2013; 8:e81618.
    • (2013) Plos ONE , vol.8
    • Zygmunt, P.M.1    Ermund, A.2    Movahed, P.3
  • 33
    • 77950634824 scopus 로고    scopus 로고
    • From surface to nuclear receptors: The endocannabinoid family extends its assets
    • Pistis M, Melis M. From surface to nuclear receptors: the endocannabinoid family extends its assets. Curr Med Chem 2010; 17:1450-67.
    • (2010) Curr Med Chem , vol.17 , pp. 1450-1467
    • Pistis, M.1    Melis, M.2
  • 34
    • 77950630872 scopus 로고    scopus 로고
    • GPR55: Current knowledge andfuture perspectives of a purported “Type-3” cannabinoid receptor
    • Moriconi A, Cerbara I, Maccarrone M, Topai A. GPR55: current knowledge andfuture perspectives of a purported “Type-3” cannabinoid receptor. Curr Med Chem 2010; 17:1411-29.
    • (2010) Curr Med Chem , vol.17 , pp. 1411-1429
    • Moriconi, A.1    Cerbara, I.2    Maccarrone, M.3    Topai, A.4
  • 35
    • 52949125632 scopus 로고    scopus 로고
    • The endocannabinoid system in peripheral lymphocytes as a mirror of neuroinflammatory diseases
    • Centonze D, Battistini L, Maccarrone M. The endocannabinoid system in peripheral lymphocytes as a mirror of neuroinflammatory diseases. Curr Pharm Des 2008; 14:2370-82.
    • (2008) Curr Pharm Des , vol.14 , pp. 2370-2382
    • Centonze, D.1    Battistini, L.2    Maccarrone, M.3
  • 37
    • 84879219708 scopus 로고    scopus 로고
    • The endocannabinoid system: A revolving plate in neuro-immune interaction in health and disease
    • Tanasescu R, Gran B, Constantinescu CS. The endocannabinoid system: a revolving plate in neuro-immune interaction in health and disease. Amino Acids 2013; 45:95-112.
    • (2013) Amino Acids , vol.45 , pp. 95-112
    • Tanasescu, R.1    Gran, B.2    Constantinescu, C.S.3
  • 38
    • 84927694130 scopus 로고    scopus 로고
    • Regulation of cannabinoid receptor gene expression and endocannabinoid levels in lymphocyte subsets by IFN-b: A longitudinal study in multiple sclerosis patients
    • Sanchez Lopez AJ, Roman-Vega L, Ramil Tojeiro E, Giuffrida A, Garcıa-Merino A. Regulation of cannabinoid receptor gene expression and endocannabinoid levels in lymphocyte subsets by IFN-b: a longitudinal study in multiple sclerosis patients. Clin Exp Immunol 2014; 179:119-27.
    • (2014) Clin Exp Immunol , vol.179 , pp. 119-127
    • Sanchez Lopez, A.J.1    Roman-Vega, L.2    Ramil Tojeiro, E.3    Giuffrida, A.4    Garcıa-Merino, A.5
  • 39
    • 0036019385 scopus 로고    scopus 로고
    • CB1 and CB2 receptor-mediated signalling: A focus on endocannabinoids
    • McAllister SD, Glass M. CB1 and CB2 receptor-mediated signalling: a focus on endocannabinoids. Prostaglandins Leukot Essent Fatty Acids 2002; 66:161-71.
    • (2002) Prostaglandins Leukot Essent Fatty Acids , vol.66 , pp. 161-171
    • McAllister, S.D.1    Glass, M.2
  • 41
    • 0029094470 scopus 로고
    • Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations
    • Galiegue S, Mary S, Marchand J et al. Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eur J Biochem 1995; 232:54-61.
    • (1995) Eur J Biochem , vol.232 , pp. 54-61
    • Galiegue, S.1    Mary, S.2    Marchand, J.3
  • 42
    • 0035816415 scopus 로고    scopus 로고
    • Differential expression of cannabinoid CB2 receptor mRNA in mouse immune cell subpopulations and following B cell stimulation
    • Lee SF, Newton C, Widen R, Friedman H, Klein TW. Differential expression of cannabinoid CB2 receptor mRNA in mouse immune cell subpopulations and following B cell stimulation. Eur J Pharmacol 2001; 423:235-41.
    • (2001) Eur J Pharmacol , vol.423 , pp. 235-241
    • Lee, S.F.1    Newton, C.2    Widen, R.3    Friedman, H.4    Klein, T.W.5
  • 43
    • 77951703978 scopus 로고    scopus 로고
    • Detailed characterisation of CB2 receptor protein expression in peripheral blood immune cells from healthy human volunteers using flow cytometry
    • Graham ES, Angel CE, Schwarcz LE, Dunbar PR, Glass M. Detailed characterisation of CB2 receptor protein expression in peripheral blood immune cells from healthy human volunteers using flow cytometry. Int J Immunopathol Pharmacol 2010; 23:25-34.
    • (2010) Int J Immunopathol Pharmacol , vol.23 , pp. 25-34
    • Graham, E.S.1    Angel, C.E.2    Schwarcz, L.E.3    Dunbar, P.R.4    Glass, M.5
  • 44
    • 0030751182 scopus 로고    scopus 로고
    • Influence of fatty acid ethanolamides and D9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells
    • Berdyshev EV, Boichot E, Germain N, Allain N, Anger JP, Lagente V. Influence of fatty acid ethanolamides and D9-tetrahydrocannabinol on cytokine and arachidonate release by mononuclear cells. Eur J Pharmacol 1997; 330:231-40.
    • (1997) Eur J Pharmacol , vol.330 , pp. 231-240
    • Berdyshev, E.V.1    Boichot, E.2    Germain, N.3    Allain, N.4    Anger, J.P.5    Lagente, V.6
  • 45
    • 34548488484 scopus 로고    scopus 로고
    • Anandamide and D9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors
    • Eisenstein TK, Meissler JJ, Wilson Q, Gaughan JP, Adler MW. Anandamide and D9-tetrahydrocannabinol directly inhibit cells of the immune system via CB2 receptors. J Neuroimmunol 2007; 189:17-22.
    • (2007) J Neuroimmunol , vol.189 , pp. 17-22
    • Eisenstein, T.K.1    Meissler, J.J.2    Wilson, Q.3    Gaughan, J.P.4    Adler, M.W.5
  • 46
    • 73949084238 scopus 로고    scopus 로고
    • Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation
    • Solorzano C, Zhu C, Battista N et al. Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation. Proc Natl Acad Sci U S A 2009; 106:20966-71.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 20966-20971
    • Solorzano, C.1    Zhu, C.2    Battista, N.3
  • 47
    • 0033801063 scopus 로고    scopus 로고
    • 2-Arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1
    • Stefano GB, Bilfinger TV, Rialas CM, Deutsch DG. 2-Arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. Pharmacol Res 2000; 42:317-22.
    • (2000) Pharmacol Res , vol.42 , pp. 317-322
    • Stefano, G.B.1    Bilfinger, T.V.2    Rialas, C.M.3    Deutsch, D.G.4
  • 49
    • 2642609451 scopus 로고    scopus 로고
    • Suppression of interleukin-2 by the putative endogenous cannabinoid 2-arachidonyl-glycerol is mediated through downregulation of the nuclear factor of activated T cells
    • Ouyang Y, Hwang SG, Han SH, Kaminski NE. Suppression of interleukin-2 by the putative endogenous cannabinoid 2-arachidonyl-glycerol is mediated through downregulation of the nuclear factor of activated T cells. Mol Pharmacol 1998; 53:676-83.
    • (1998) Mol Pharmacol , vol.53 , pp. 676-683
    • Ouyang, Y.1    Hwang, S.G.2    Han, S.H.3    Kaminski, N.E.4
  • 50
    • 20044386146 scopus 로고    scopus 로고
    • 2-Arachidonoyl-glycerol suppresses interferon-c production in phorbol ester/ionomycin-activated mouse splenocytes independent of CB1 or CB2
    • Kaplan BL, Ouyang Y, Rockwell CE, Rao GK, Kaminski NE. 2-Arachidonoyl-glycerol suppresses interferon-c production in phorbol ester/ionomycin-activated mouse splenocytes independent of CB1 or CB2. J Leukoc Biol 2005; 77:966-74.
    • (2005) J Leukoc Biol , vol.77 , pp. 966-974
    • Kaplan, B.L.1    Ouyang, Y.2    Rockwell, C.E.3    Rao, G.K.4    Kaminski, N.E.5
  • 51
    • 1342303482 scopus 로고    scopus 로고
    • Of mice and not men: Differences between mouse and human immunology
    • Mestas J, Hughes CC. Of mice and not men: differences between mouse and human immunology. J Immunol 2004; 172:2731-8.
    • (2004) J Immunol , vol.172 , pp. 2731-2738
    • Mestas, J.1    Hughes, C.C.2
  • 52
    • 84901358607 scopus 로고    scopus 로고
    • Monocytes and macrophages: Developmental pathways and tissue homeostasis
    • Ginhoux F, Jung S. Monocytes and macrophages: developmental pathways and tissue homeostasis. Nat Rev Immunol 2014; 14:392-404.
    • (2014) Nat Rev Immunol , vol.14 , pp. 392-404
    • Ginhoux, F.1    Jung, S.2
  • 53
    • 26444525004 scopus 로고    scopus 로고
    • Involvement of N-a-cylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages
    • Sun YX, Tsuboi K, Zhao LY, Okamoto Y, Lambert DM, Ueda N. Involvement of N-a-cylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages. Biochim Biophys Acta 2005; 1736:211-20.
    • (2005) Biochim Biophys Acta , vol.1736 , pp. 211-220
    • Sun, Y.X.1    Tsuboi, K.2    Zhao, L.Y.3    Okamoto, Y.4    Lambert, D.M.5    Ueda, N.6
  • 54
    • 26844448746 scopus 로고    scopus 로고
    • Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
    • Maresz K, Carrier EJ, Ponomarev ED, Hillard CJ, Dittel BN. Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. J Neurochem 2005; 95:437-45.
    • (2005) J Neurochem , vol.95 , pp. 437-445
    • Maresz, K.1    Carrier, E.J.2    Ponomarev, E.D.3    Hillard, C.J.4    Dittel, B.N.5
  • 55
    • 60149087884 scopus 로고    scopus 로고
    • Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages
    • Jiang LS, Pu J, Han ZH, Hu LH, He B. Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages. Cardiovasc Res 2009; 81:805-13.
    • (2009) Cardiovasc Res , vol.81 , pp. 805-813
    • Jiang, L.S.1    Pu, J.2    Han, Z.H.3    Hu, L.H.4    He, B.5
  • 56
    • 59049102067 scopus 로고    scopus 로고
    • Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid 1 receptor blockade on macrophages
    • Sugamura K, Sugiyama S, Nozaki T et al. Activated endocannabinoid system in coronary artery disease and antiinflammatory effects of cannabinoid 1 receptor blockade on macrophages. Circulation 2009; 119:28-36.
    • (2009) Circulation , vol.119 , pp. 28-36
    • Sugamura, K.1    Sugiyama, S.2    Nozaki, T.3
  • 57
    • 84893865143 scopus 로고    scopus 로고
    • Detailed characterization of the endocannabinoid system in human macrophages and foam cells, and anti-inflammatory role of type-2 cannabinoid receptor
    • Chiurchiu V, Lanuti M, Catanzaro G, Fezza F, Rapino C, Maccarrone M. Detailed characterization of the endocannabinoid system in human macrophages and foam cells, and anti-inflammatory role of type-2 cannabinoid receptor. Atherosclerosis 2014; 233:55-63.
    • (2014) Atherosclerosis , vol.233 , pp. 55-63
    • Chiurchiu, V.1    Lanuti, M.2    Catanzaro, G.3    Fezza, F.4    Rapino, C.5    Maccarrone, M.6
  • 58
    • 0029756752 scopus 로고    scopus 로고
    • Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells
    • Di Marzo V, De Petrocellis L, Sepe N, Buono A. Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells. Biochem J 1996; 316:977-84.
    • (1996) Biochem J , vol.316 , pp. 977-984
    • Di Marzo, V.1    De Petrocellis, L.2    Sepe, N.3    Buono, A.4
  • 59
    • 0031031557 scopus 로고    scopus 로고
    • Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes
    • Bisogno T, Maurelli S, Melck D, De Petrocellis L, Di Marzo V. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. J Biol Chem 1997; 272:3315-23.
    • (1997) J Biol Chem , vol.272 , pp. 3315-3323
    • Bisogno, T.1    Maurelli, S.2    Melck, D.3    De Petrocellis, L.4    Di Marzo, V.5
  • 60
    • 0035012848 scopus 로고    scopus 로고
    • Effects of cannabinoids on LPS-stimulated inflammatory mediator release from macrophages: Involvement of eicosanoids
    • Chang YH, Lee ST, Lin WW. Effects of cannabinoids on LPS-stimulated inflammatory mediator release from macrophages: involvement of eicosanoids. J Cell Biochem 2001;81:715-23.
    • (2001) J Cell Biochem , vol.81 , pp. 715-723
    • Chang, Y.H.1    Lee, S.T.2    Lin, W.W.3
  • 61
    • 79952996326 scopus 로고    scopus 로고
    • Proin-flammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages
    • Zhu C, Solorzano C, Sahar S, Realini N, Fung E, Sassone-Corsi P, Piomelli D. Proin-flammatory stimuli control N-acylphosphatidylethanolamine-specific phospholipase D expression in macrophages. Mol Pharmacol 2011; 79:786-92.
    • (2011) Mol Pharmacol , vol.79 , pp. 786-792
    • Zhu, C.1    Solorzano, C.2    Sahar, S.3    Realini, N.4    Fung, E.5    Sassone-Corsi, P.6    Piomelli, D.7
  • 62
    • 84867267832 scopus 로고    scopus 로고
    • Evidence for bidirectional endocannabinoid transport across cell membranes
    • Chicca A, Marazzi J, Nicolussi S, Gertsch J. Evidence for bidirectional endocannabinoid transport across cell membranes. J Biol Chem 2012; 287:34660-82.
    • (2012) J Biol Chem , vol.287 , pp. 34660-34682
    • Chicca, A.1    Marazzi, J.2    Nicolussi, S.3    Gertsch, J.4
  • 63
    • 0036891996 scopus 로고    scopus 로고
    • Estrogen stimulates arachidonoy-lethanolamide release from human endothelial cells and platelet activation
    • Maccarrone M, Bari M, Battista N, Finazzi-Agro A. Estrogen stimulates arachidonoy-lethanolamide release from human endothelial cells and platelet activation. Blood 2002; 100:4040-8.
    • (2002) Blood , vol.100 , pp. 4040-4048
    • Maccarrone, M.1    Bari, M.2    Battista, N.3    Finazzi-Agro, A.4
  • 65
    • 0034604755 scopus 로고    scopus 로고
    • Inhibition of nitric oxide production in RAW264 7 macrophages by cannabinoids and palmitoylethanolamide
    • Ross RA, Brockie HC, Pertwee RG. Inhibition of nitric oxide production in RAW264.7 macrophages by cannabinoids and palmitoylethanolamide. Eur J Pharmacol 2000; 401:121-30.
    • (2000) Eur J Pharmacol , vol.401 , pp. 121-130
    • Ross, R.A.1    Brockie, H.C.2    Pertwee, R.G.3
  • 66
    • 38949143238 scopus 로고    scopus 로고
    • Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: Possible involvement of the COX-2 metabolite prostamide E2
    • Correa F, Docagne F, Clemente D, Mestre L, Becker C, Guaza C. Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite prostamide E2. Biochem J 2008; 409:761-70.
    • (2008) Biochem J , vol.409 , pp. 761-770
    • Correa, F.1    Docagne, F.2    Clemente, D.3    Mestre, L.4    Becker, C.5    Guaza, C.6
  • 67
    • 73149113054 scopus 로고    scopus 로고
    • Anandamide enhances IL-10 production in activated microglia by targeting CB2 receptors: Roles of ERK1/2, JNK, and NF-jB
    • Correa F, Hernangomez M, Mestre L, Lorıa F, Spagnolo A, Docagne F, Di Marzo V, Guaza C. Anandamide enhances IL-10 production in activated microglia by targeting CB2 receptors: roles of ERK1/2, JNK, and NF-jB. Glia 2010; 58:135-47.
    • (2010) Glia , vol.58 , pp. 135-147
    • Correa, F.1    Hernangomez, M.2    Mestre, L.3    Lorıa, F.4    Spagnolo, A.5    Docagne, F.6    Di Marzo, V.7    Guaza, C.8
  • 68
    • 79954937143 scopus 로고    scopus 로고
    • The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: Evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells
    • Correa F, Hernangomez-Herrero M, Mestre L, Lorıa F, Docagne F, Guaza C. The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells. Brain Behav Immun 2011; 25:736-49.
    • (2011) Brain Behav Immun , vol.25 , pp. 736-749
    • Correa, F.1    Hernangomez-Herrero, M.2    Mestre, L.3    Lorıa, F.4    Docagne, F.5    Guaza, C.6
  • 69
    • 84864002613 scopus 로고    scopus 로고
    • CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation
    • Hernangomez M, Mestre L, Correa FG et al. CD200-CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation. Glia 2012; 60:1437-50.
    • (2012) Glia , vol.60 , pp. 1437-1450
    • Hernangomez, M.1    Mestre, L.2    Correa, F.G.3
  • 70
    • 39749087583 scopus 로고    scopus 로고
    • Involvement of cannabinoid receptor CB2 in dectin-1-mediated macrophage phagocytosis
    • Shiratsuchi A, Watanabe I, Yoshida H, Nakanishi Y. Involvement of cannabinoid receptor CB2 in dectin-1-mediated macrophage phagocytosis. Immunol Cell Biol 2008; 86:179-84.
    • (2008) Immunol Cell Biol , vol.86 , pp. 179-184
    • Shiratsuchi, A.1    Watanabe, I.2    Yoshida, H.3    Nakanishi, Y.4
  • 71
    • 84857910035 scopus 로고    scopus 로고
    • Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 and Streptococcus pneumoniae R6 by microglial cells
    • Redlich S, Ribes S, Schutze S, Czesnik D, Nau R. Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 and Streptococcus pneumoniae R6 by microglial cells. J Neuroimmunol 2012; 244:32-4.
    • (2012) J Neuroimmunol , vol.244 , pp. 32-34
    • Redlich, S.1    Ribes, S.2    Schutze, S.3    Czesnik, D.4    Nau, R.5
  • 72
    • 84902066500 scopus 로고    scopus 로고
    • Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections
    • Redlich S, Ribes S, Schutze S, Nau R. Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections. J Neuroinflammation 2014; 11:108.
    • (2014) J Neuroinflammation , vol.11 , pp. 108
    • Redlich, S.1    Ribes, S.2    Schutze, S.3    Nau, R.4
  • 73
    • 0042320663 scopus 로고    scopus 로고
    • Palmitoylethan-olamide increases after focal cerebral ischemia and potentiates microglial cell motility
    • Franklin A, Parmentier-Batteur S, Walter L, Greenberg DA, Stella N. Palmitoylethan-olamide increases after focal cerebral ischemia and potentiates microglial cell motility. J Neurosci 2003; 23:7767-75.
    • (2003) J Neurosci , vol.23 , pp. 7767-7775
    • Franklin, A.1    Parmentier-Batteur, S.2    Walter, L.3    Greenberg, D.A.4    Stella, N.5
  • 74
    • 84893551659 scopus 로고    scopus 로고
    • Mast cells, glia and neuroinflammation: Partners in crime?
    • Skaper SD, Facci L, Giusti P. Mast cells, glia and neuroinflammation: partners in crime? Immunology 2014; 141:314-27.
    • (2014) Immunology , vol.141 , pp. 314-327
    • Skaper, S.D.1    Facci, L.2    Giusti, P.3
  • 75
    • 0034613209 scopus 로고    scopus 로고
    • 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-a production in murine macrophages, and in mice
    • Gallily R, Breuer A, Mechoulam R. 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-a production in murine macrophages, and in mice. Eur J Pharmacol 2000; 406:R5-7.
    • (2000) Eur J Pharmacol , vol.406 , pp. R5-R7
    • Gallily, R.1    Breuer, A.2    Mechoulam, R.3
  • 76
    • 79955610081 scopus 로고    scopus 로고
    • Administration of 2-arachidonoylglycerol ameliorates both acute and chronic experimental autoimmune encephalomyelitis
    • Lourbopoulos A, Grigoriadis N, Lagoudaki R et al. Administration of 2-arachidonoylglycerol ameliorates both acute and chronic experimental autoimmune encephalomyelitis. Brain Res 2011; 1390:126-41.
    • (2011) Brain Res , vol.1390 , pp. 126-141
    • Lourbopoulos, A.1    Grigoriadis, N.2    Lagoudaki, R.3
  • 77
    • 2442706289 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells
    • ª 2015 John Wiley & Sons Ltd, Immunology, 144, 352-364
    • Kishimoto S, Kobayashi Y, Oka S, Gokoh M, Waku K, Sugiura T. 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells. J Biochem 2004; 135:517-24.ª 2015 John Wiley & Sons Ltd, Immunology, 144, 352-364
    • (2004) J Biochem , vol.135 , pp. 517-524
    • Kishimoto, S.1    Kobayashi, Y.2    Oka, S.3    Gokoh, M.4    Waku, K.5    Sugiura, T.6
  • 78
    • 0042591269 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol induces the migration of HL-60 cells differentiated into macro-phage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism
    • Kishimoto S, Gokoh M, Oka S, Muramatsu M, Kajiwara T, Waku K, Sugiura T. 2-Arachidonoylglycerol induces the migration of HL-60 cells differentiated into macro-phage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism. J Biol Chem 2003; 278:24469-75.
    • (2003) J Biol Chem , vol.278 , pp. 24469-24475
    • Kishimoto, S.1    Gokoh, M.2    Oka, S.3    Muramatsu, M.4    Kajiwara, T.5    Waku, K.6    Sugiura, T.7
  • 79
    • 27744493300 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, enhances the adhesion of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes
    • Gokoh M, Kishimoto S, Oka S, Metani Y, Sugiura T. 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, enhances the adhesion of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes. FEBS Lett 2005; 579:6473-8.
    • (2005) FEBS Lett , vol.579 , pp. 6473-6478
    • Gokoh, M.1    Kishimoto, S.2    Oka, S.3    Metani, Y.4    Sugiura, T.5
  • 80
    • 34447129568 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol enhances the phagocytosis of opsonized zymosan by HL-60 cells differentiated into macrophage-like cells
    • Gokoh M, Kishimoto S, Oka S, Sugiura T. 2-Arachidonoylglycerol enhances the phagocytosis of opsonized zymosan by HL-60 cells differentiated into macrophage-like cells. Biol Pharm Bull 2007; 30:1199-205.
    • (2007) Biol Pharm Bull , vol.30 , pp. 1199-1205
    • Gokoh, M.1    Kishimoto, S.2    Oka, S.3    Sugiura, T.4
  • 81
    • 84901791811 scopus 로고    scopus 로고
    • COX-2-derived endocannabinoid metabolites as novel inflammatory mediators
    • Alhouayek M, Muccioli GG. COX-2-derived endocannabinoid metabolites as novel inflammatory mediators. Trends Pharmacol Sci 2014; 35:284-92.
    • (2014) Trends Pharmacol Sci , vol.35 , pp. 284-292
    • Alhouayek, M.1    Muccioli, G.G.2
  • 82
    • 84875528275 scopus 로고    scopus 로고
    • The dendritic cell lineage: Ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
    • Merad M, Sathe P, Helft J, Miller J, Mortha A. The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu Rev Immunol 2013; 31:563-604.
    • (2013) Annu Rev Immunol , vol.31 , pp. 563-604
    • Merad, M.1    Sathe, P.2    Helft, J.3    Miller, J.4    Mortha, A.5
  • 84
    • 10044257545 scopus 로고    scopus 로고
    • The endogenous cannabinoid 2-arachidonoyl glycerol as in vivo chemo-attractant for dendritic cells and adjuvant for Th1 response to a soluble protein
    • Maestroni GJ. The endogenous cannabinoid 2-arachidonoyl glycerol as in vivo chemo-attractant for dendritic cells and adjuvant for Th1 response to a soluble protein. FASEB J 2004; 18:1914-6.
    • (2004) FASEB J , vol.18 , pp. 1914-1916
    • Maestroni, G.J.1
  • 85
    • 4043179097 scopus 로고    scopus 로고
    • Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-jB-dependent apoptosis: Novel role for endogenous and exogenous cannabinoids in immunoregulation
    • Do Y, McKallip RJ, Nagarkatti M, Nagarkatti PS. Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-jB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation. J Immunol 2004; 173:2373-82.
    • (2004) J Immunol , vol.173 , pp. 2373-2382
    • Do, Y.1    McKallip, R.J.2    Nagarkatti, M.3    Nagarkatti, P.S.4
  • 86
    • 80055070153 scopus 로고    scopus 로고
    • Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection
    • Karmaus PW, Chen W, Crawford RB, Harkema JR, Kaplan BL, Kaminski NE. Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection. J Leukoc Biol 2011; 90:983-95.
    • (2011) J Leukoc Biol , vol.90 , pp. 983-995
    • Karmaus, P.W.1    Chen, W.2    Crawford, R.B.3    Harkema, J.R.4    Kaplan, B.L.5    Kaminski, N.E.6
  • 88
    • 84878320781 scopus 로고    scopus 로고
    • Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis
    • Chiurchiu V, Cencioni MT, Bisicchia E et al. Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis. Ann Neurol 2013; 73:626-36.
    • (2013) Ann Neurol , vol.73 , pp. 626-636
    • Chiurchiu, V.1    Cencioni, M.T.2    Bisicchia, E.3
  • 89
    • 84880676381 scopus 로고    scopus 로고
    • Diverse novel functions of neutrophils in immunity, inflammation, and beyond
    • Mocsai A. Diverse novel functions of neutrophils in immunity, inflammation, and beyond. J Exp Med 2013; 210:1283-99.
    • (2013) J Exp Med , vol.210 , pp. 1283-1299
    • Mocsai, A.1
  • 91
    • 12444270066 scopus 로고    scopus 로고
    • New perspectives in the studies on endocannabinoid and cannabis 2-arachidonoylglycerol as a possible novel mediator of inflammation
    • Sugiura T, Oka S, Gokoh M, Kishimoto S, Waku K. New perspectives in the studies on endocannabinoid and cannabis: 2-arachidonoylglycerol as a possible novel mediator of inflammation. J Pharmacol Sci 2004; 96:367-75.
    • (2004) J Pharmacol Sci , vol.96 , pp. 367-375
    • Sugiura, T.1    Oka, S.2    Gokoh, M.3    Kishimoto, S.4    Waku, K.5
  • 92
    • 17044390454 scopus 로고    scopus 로고
    • Endogenous cannabinoid receptor ligand induces the migration of human natural killer cells
    • Kishimoto S, Muramatsu M, Gokoh M, Oka S, Waku K, Sugiura T. Endogenous cannabinoid receptor ligand induces the migration of human natural killer cells. J Biochem 2005; 137:217-23.
    • (2005) J Biochem , vol.137 , pp. 217-223
    • Kishimoto, S.1    Muramatsu, M.2    Gokoh, M.3    Oka, S.4    Waku, K.5    Sugiura, T.6
  • 93
    • 85003422570 scopus 로고    scopus 로고
    • The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells
    • pii dxu097
    • Chiurchiu V, Lanuti M, De Bardi M, Battistini L, Maccarrone M. The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells. Int Immunol 2014; pii: dxu097.
    • (2014) Int Immunol
    • Chiurchiu, V.1    Lanuti, M.2    De Bardi, M.3    Battistini, L.4    Maccarrone, M.5
  • 94
    • 38549130466 scopus 로고    scopus 로고
    • Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: Evidence for a site distinct from CB1 and CB2
    • McHugh D, Tanner C, Mechoulam R, Pertwee RG, Ross RA. Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: evidence for a site distinct from CB1 and CB2. Mol Pharmacol 2008; 73:441-50.
    • (2008) Mol Pharmacol , vol.73 , pp. 441-450
    • McHugh, D.1    Tanner, C.2    Mechoulam, R.3    Pertwee, R.G.4    Ross, R.A.5
  • 95
    • 42749086767 scopus 로고    scopus 로고
    • Anandamide and neutrophil function in patients with fibromyalgia
    • Kaufmann I, Schelling G, Eisner C et al. Anandamide and neutrophil function in patients with fibromyalgia. Psychoneuroendocrinology 2008; 33:676-85.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 676-685
    • Kaufmann, I.1    Schelling, G.2    Eisner, C.3
  • 96
    • 2942560977 scopus 로고    scopus 로고
    • Cannabinoid receptor-independent suppressionof the superoxide generation of human neutrophils (PMN) by CP55 940, but not by anandamide
    • Kraft B, Wintersberger W, Kress HG. Cannabinoid receptor-independent suppressionof the superoxide generation of human neutrophils (PMN) by CP55 940, but not by anandamide. Life Sci 2004; 75:969-77.
    • (2004) Life Sci , vol.75 , pp. 969-977
    • Kraft, B.1    Wintersberger, W.2    Kress, H.G.3
  • 97
    • 27144518080 scopus 로고    scopus 로고
    • Indirect CB2 receptor and mediator-dependent stimulation of human whole-blood neutrophils by exogenous and endogenous cannabinoids
    • Kraft B, Kress HG. Indirect CB2 receptor and mediator-dependent stimulation of human whole-blood neutrophils by exogenous and endogenous cannabinoids. J Pharmacol Exp Ther 2005; 315:641-7.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 641-647
    • Kraft, B.1    Kress, H.G.2
  • 98
    • 84859496535 scopus 로고    scopus 로고
    • The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques
    • Montecucco F, Di Marzo V, da Silva RF et al. The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques. Eur Heart J 2012; 33:846-56.
    • (2012) Eur Heart J , vol.33 , pp. 846-856
    • Montecucco, F.1    Di Marzo, V.2    Da Silva, R.F.3
  • 99
    • 79952751764 scopus 로고    scopus 로고
    • The endocannabinoid 2-arachidonoyl-glyc-erol activates human neutrophils: Critical role of its hydrolysis and de novo leukotriene B4 biosynthesis
    • Chouinard F, Lefebvre JS, Navarro P et al. The endocannabinoid 2-arachidonoyl-glyc-erol activates human neutrophils: critical role of its hydrolysis and de novo leukotriene B4 biosynthesis. J Immunol 2011; 186:3188-96.
    • (2011) J Immunol , vol.186 , pp. 3188-3196
    • Chouinard, F.1    Lefebvre, J.S.2    Navarro, P.3
  • 100
    • 84873325325 scopus 로고    scopus 로고
    • 2-Arachidonoyl-glycerol- and arachidonic acid-stimulated neutrophils release antimicrobial effectors against
    • Chouinard F, Turcotte C, Guan X et al. 2-Arachidonoyl-glycerol- and arachidonic acid-stimulated neutrophils release antimicrobial effectors against E. coli, S. aureus, HSV-1, and RSV. J Leukoc Biol 2013; 93:267-76.
    • (2013) E. Coli, S. Aureus, HSV-1, and RSV. J Leukoc Biol , vol.93 , pp. 267-276
    • Chouinard, F.1    Turcotte, C.2    Guan, X.3
  • 101
    • 33744948790 scopus 로고    scopus 로고
    • Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils
    • Kurihara R, Tohyama Y, Matsusaka S, Naruse H, Kinoshita E, Tsujioka T, Katsumata Y, Yamamura H. Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils. J Biol Chem 2006; 281:12908-18.
    • (2006) J Biol Chem , vol.281 , pp. 12908-12918
    • Kurihara, R.1    Tohyama, Y.2    Matsusaka, S.3    Naruse, H.4    Kinoshita, E.5    Tsujioka, T.6    Katsumata, Y.7    Yamamura, H.8
  • 102
    • 84876913029 scopus 로고    scopus 로고
    • Protective and pathological roles of mast cells and basophils
    • Voehringer D. Protective and pathological roles of mast cells and basophils. Nat Rev Immunol 2013; 13:362-75.
    • (2013) Nat Rev Immunol , vol.13 , pp. 362-375
    • Voehringer, D.1
  • 103
    • 84868608435 scopus 로고    scopus 로고
    • The expanding role(S) of eosinophils in health and disease
    • Jacobsen EA, Helmers RA, Lee JJ, Lee NA. The expanding role(s) of eosinophils in health and disease. Blood 2012; 120:3882-90.
    • (2012) Blood , vol.120 , pp. 3882-3890
    • Jacobsen, E.A.1    Helmers, R.A.2    Lee, J.J.3    Lee, N.A.4
  • 104
    • 7644244850 scopus 로고    scopus 로고
    • 2-Arachi-donoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils
    • Oka S, Ikeda S, Kishimoto S, Gokoh M, Yanagimoto S, Waku K, Sugiura T. 2-Arachi-donoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils. J Leukoc Biol 2004; 76:1002-9.
    • (2004) J Leukoc Biol , vol.76 , pp. 1002-1009
    • Oka, S.1    Ikeda, S.2    Kishimoto, S.3    Gokoh, M.4    Yanagimoto, S.5    Waku, K.6    Sugiura, T.7
  • 105
    • 33745065869 scopus 로고    scopus 로고
    • Chemotaxis of human peripheral blood eosinophils to 2-arachidonoylglycerol: Comparison with other eosinophil chemoattractants
    • Kishimoto S, Oka S, Gokoh M, Sugiura T. Chemotaxis of human peripheral blood eosinophils to 2-arachidonoylglycerol: comparison with other eosinophil chemoattractants. Int Arch Allergy Immunol 2006; 140:3-7.
    • (2006) Int Arch Allergy Immunol , vol.140 , pp. 3-7
    • Kishimoto, S.1    Oka, S.2    Gokoh, M.3    Sugiura, T.4
  • 106
    • 33845383265 scopus 로고    scopus 로고
    • Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachido-noylglycerol in oxazolone-induced contact dermatitis in mice
    • Oka S, Wakui J, Ikeda S, Yanagimoto S, Kishimoto S, Gokoh M, Nasui M, Sugiura T. Involvement of the cannabinoid CB2 receptor and its endogenous ligand 2-arachido-noylglycerol in oxazolone-induced contact dermatitis in mice. J Immunol 2006; 177:8796-805.
    • (2006) J Immunol , vol.177 , pp. 8796-8805
    • Oka, S.1    Wakui, J.2    Ikeda, S.3    Yanagimoto, S.4    Kishimoto, S.5    Gokoh, M.6    Nasui, M.7    Sugiura, T.8
  • 108
    • 0028906566 scopus 로고
    • Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide
    • Facci L, Dal Toso R, Romanello S, Buriani A, Skaper SD, Leon A. Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide. Proc Natl Acad Sci U S A 1995; 92:3376-80.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3376-3380
    • Facci, L.1    Dal Toso, R.2    Romanello, S.3    Buriani, A.4    Skaper, S.D.5    Leon, A.6
  • 109
    • 84922393495 scopus 로고    scopus 로고
    • Palmitoylethanolamide regulates development of intestinal radiation injury in a mast cell-dependent manner
    • Wang J, Zheng J, Kulkarni A, Wang W, Garg S, Prather PL, Hauer-Jensen M. Palmitoylethanolamide regulates development of intestinal radiation injury in a mast cell-dependent manner. Dig Dis Sci 2014; 59:2693-703.
    • (2014) Dig Dis Sci , vol.59 , pp. 2693-2703
    • Wang, J.1    Zheng, J.2    Kulkarni, A.3    Wang, W.4    Garg, S.5    Prather, P.L.6    Hauer-Jensen, M.7
  • 111
    • 53349089891 scopus 로고    scopus 로고
    • The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: Involvement of CB1, TRPV1 and PPARc receptors and neurotrophic factors
    • Costa B, Comelli F, Bettoni I, Colleoni M, Giagnoni G. The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: involvement of CB1, TRPV1 and PPARc receptors and neurotrophic factors. Pain 2008; 139:541-50.
    • (2008) Pain , vol.139 , pp. 541-550
    • Costa, B.1    Comelli, F.2    Bettoni, I.3    Colleoni, M.4    Giagnoni, G.5
  • 112
    • 79960209448 scopus 로고    scopus 로고
    • Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury
    • Esposito E, Paterniti I, Mazzon E, Genovese T, Di Paola R, Galuppo M, Cuzzocrea S. Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury. Brain Behav Immun 2011; 25:1099-112.
    • (2011) Brain Behav Immun , vol.25 , pp. 1099-1112
    • Esposito, E.1    Paterniti, I.2    Mazzon, E.3    Genovese, T.4    Di Paola, R.5    Galuppo, M.6    Cuzzocrea, S.7
  • 113
    • 84875353344 scopus 로고    scopus 로고
    • Non-neuronal cell modulation relieves neuropathic pain: Efficacy of the endogenous lipid palmitoylethanolamide
    • Bettoni I, Comelli F, Colombo A, Bonfanti P, Costa B. Non-neuronal cell modulation relieves neuropathic pain: efficacy of the endogenous lipid palmitoylethanolamide. CNS Neurol Disord Drug Targets 2013; 12:34-44.
    • (2013) CNS Neurol Disord Drug Targets , vol.12 , pp. 34-44
    • Bettoni, I.1    Comelli, F.2    Colombo, A.3    Bonfanti, P.4    Costa, B.5
  • 115
    • 84857795853 scopus 로고    scopus 로고
    • Endocannabinoids limit excessive mast cell maturation and activation in human skin
    • Sugawara K, Bıro T, Tsuruta D et al. Endocannabinoids limit excessive mast cell maturation and activation in human skin. J Allergy Clin Immunol 2012; 129:726-38.e8.
    • (2012) J Allergy Clin Immunol , vol.129 , pp. 726-738
    • Sugawara, K.1    Bıro, T.2    Tsuruta, D.3
  • 116
    • 84882852600 scopus 로고    scopus 로고
    • Cannabinoid receptor 1 controls human mucosal-type mast cell degranulation and maturation in situ
    • Sugawara K, Zakany N, Hundt T et al. Cannabinoid receptor 1 controls human mucosal-type mast cell degranulation and maturation in situ. J Allergy Clin Immunol 2013; 132:182-93.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 182-193
    • Sugawara, K.1    Zakany, N.2    Hundt, T.3
  • 117
    • 84899811334 scopus 로고    scopus 로고
    • Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1
    • Jackson AR, Hegde VL, Nagarkatti PS, Nagarkatti M. Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1. J Leukoc Biol 2014; 95:609-19.
    • (2014) J Leukoc Biol , vol.95 , pp. 609-619
    • Jackson, A.R.1    Hegde, V.L.2    Nagarkatti, P.S.3    Nagarkatti, M.4
  • 119
    • 0027999501 scopus 로고
    • Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis
    • Schwarz H, Blanco FJ, Lotz M. Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. J Neuroimmunol 1994; 55:107-15.
    • (1994) J Neuroimmunol , vol.55 , pp. 107-115
    • Schwarz, H.1    Blanco, F.J.2    Lotz, M.3
  • 120
    • 84899458904 scopus 로고    scopus 로고
    • Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction
    • Jackson AR, Nagarkatti P, Nagarkatti M. Anandamide attenuates Th-17 cell-mediated delayed-type hypersensitivity response by triggering IL-10 production and consequent microRNA induction. PLoS ONE 2014; 9:e93954.
    • (2014) Plos ONE , vol.9
    • Jackson, A.R.1    Nagarkatti, P.2    Nagarkatti, M.3
  • 121
    • 0037308775 scopus 로고    scopus 로고
    • Anandamide inhibits nuclear factor-jB activation through a cannabinoid receptor-independent pathway
    • Sancho R, Calzado MA, Di Marzo V, Appendino G, Munoz E. Anandamide inhibits nuclear factor-jB activation through a cannabinoid receptor-independent pathway. Mol Pharmacol 2003; 63:429-38.
    • (2003) Mol Pharmacol , vol.63 , pp. 429-438
    • Sancho, R.1    Calzado, M.A.2    Di Marzo, V.3    Appendino, G.4    Munoz, E.5
  • 122
    • 46649101803 scopus 로고    scopus 로고
    • A COX-2 metabolite of the endogenous cannabinoid, 2-arachidonyl glycerol, mediates suppression of IL-2 secretion in activated Jurkat T cells
    • Rockwell CE, Raman P, Kaplan BL, Kaminski NE. A COX-2 metabolite of the endogenous cannabinoid, 2-arachidonyl glycerol, mediates suppression of IL-2 secretion in activated Jurkat T cells. Biochem Pharmacol 2008; 76:353-61.
    • (2008) Biochem Pharmacol , vol.76 , pp. 353-361
    • Rockwell, C.E.1    Raman, P.2    Kaplan, B.L.3    Kaminski, N.E.4
  • 123
    • 3242724820 scopus 로고    scopus 로고
    • Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes
    • Joseph J, Niggemann B, Zaenker KS, Entschladen F. Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. Cancer Immunol Immunother 2004; 53:723-8.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 723-728
    • Joseph, J.1    Niggemann, B.2    Zaenker, K.S.3    Entschladen, F.4
  • 124
    • 29244469635 scopus 로고    scopus 로고
    • Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis
    • Malfitano AM, Matarese G, Pisanti S et al. Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis. J Neuroimmunol 2006; 171:110-9.
    • (2006) J Neuroimmunol , vol.171 , pp. 110-119
    • Malfitano, A.M.1    Matarese, G.2    Pisanti, S.3
  • 125
    • 77952493930 scopus 로고    scopus 로고
    • Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors
    • Chiurchiu V, Catanzaro G, Borsellino G, Bernardi G, Battistini L, Maccarrone M. Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors. PLoS ONE 2010; 5:e8688.
    • (2010) Plos ONE , vol.5
    • Chiurchiu, V.1    Catanzaro, G.2    Borsellino, G.3    Bernardi, G.4    Battistini, L.5    Maccarrone, M.6
  • 126
    • 0035877059 scopus 로고    scopus 로고
    • Progesterone up-regulates anandamide hydrolase in human lymphocytes: Role of cytokines and implications for fertility
    • Maccarrone M, Valensise H, Bari M, Lazzarin N, Romanini C, Finazzi-Agro A. Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. J Immunol 2001; 166:7183-9.
    • (2001) J Immunol , vol.166 , pp. 7183-7189
    • Maccarrone, M.1    Valensise, H.2    Bari, M.3    Lazzarin, N.4    Romanini, C.5    Finazzi-Agro, A.6
  • 127
    • 58149173502 scopus 로고    scopus 로고
    • The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation
    • Lissoni P, Tintori A, Fumagalli L et al. The endocannabinoid anandamide neither impairs in vitro T-cell function nor induces regulatory T-cell generation. Anticancer Res 2008; 28:3743-8.
    • (2008) Anticancer Res , vol.28 , pp. 3743-3748
    • Lissoni, P.1    Tintori, A.2    Fumagalli, L.3
  • 128
    • 22144477141 scopus 로고    scopus 로고
    • Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: Possible risk for autoimmune disorders
    • Sipe JC, Arbour N, Gerber A, Beutler E. Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: possible risk for autoimmune disorders. J Leukoc Biol 2005; 78:231-8.
    • (2005) J Leukoc Biol , vol.78 , pp. 231-238
    • Sipe, J.C.1    Arbour, N.2    Gerber, A.3    Beutler, E.4
  • 130
    • 33745280979 scopus 로고    scopus 로고
    • Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor c independently of cannabinoid receptors 1 and 2
    • Rockwell CE, Snider NT, Thompson JT, Vanden Heuvel JP, Kaminski NE. Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor c independently of cannabinoid receptors 1 and 2. Mol Pharmacol 2006; 70:101-11.
    • (2006) Mol Pharmacol , vol.70 , pp. 101-111
    • Rockwell, C.E.1    Snider, N.T.2    Thompson, J.T.3    Vanden Heuvel, J.P.4    Kaminski, N.E.5
  • 132
    • 70449336285 scopus 로고    scopus 로고
    • Identification of transcription start sites and preferential expression of select cb2 transcripts in mouse and human b lymphocytes
    • Sherwood TA, Nong L, Agudelo M, Newton C, Widen R, Klein TW. Identification of transcription start sites and preferential expression of select CB2 transcripts in mouse and human B lymphocytes. J Neuroimmune Pharmacol 2009; 4:476–88.
    • (2009) J Neuroimmune Pharmacol , vol.4 , pp. 476-488
    • Sherwood, T.A.1    Nong, L.2    Agudelo, M.3    Newton, C.4    Widen, R.5    Klein, T.W.6
  • 133
    • 0032533247 scopus 로고    scopus 로고
    • Modulation and functional involvement of cb2 peripheral cannabinoid receptors during b-cell differentiation
    • Carayon P, Marchand J, Dussossoy D et al. Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation. Blood 1998; 92:3605–15.
    • (1998) Blood , vol.92 , pp. 3605-3615
    • Carayon, P.1    Marchand, J.2    Dussossoy, D.3
  • 134
    • 62849091467 scopus 로고    scopus 로고
    • Cannabinoid receptor 2 mediates the retention of immature b cells in bone marrow sinusoids
    • Pereira JP, An J, Xu Y, Huang Y, Cyster JG. Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoids. Nat Immunol 2009; 10:403–11.
    • (2009) Nat Immunol , vol.10 , pp. 403-411
    • Pereira, J.P.1    An, J.2    Xu, Y.3    Huang, Y.4    Cyster, J.G.5
  • 136
    • 38949203366 scopus 로고    scopus 로고
    • Cannabinoid receptor 2 (cb2) mediates immunoglobulin class switching from igm to ige in cultures of murine-purified b lymphocytes
    • Agudelo M, Newton C, Widen R, Sherwood T, Nong L, Friedman H, Klein TW. Cannabinoid receptor 2 (CB2) mediates immunoglobulin class switching from IgM to IgE in cultures of murine-purified B lymphocytes. J Neuroimmune Pharmacol 2008; 3:35–42.
    • (2008) J Neuroimmune Pharmacol , vol.3 , pp. 35-42
    • Agudelo, M.1    Newton, C.2    Widen, R.3    Sherwood, T.4    Nong, L.5    Friedman, H.6    Klein, T.W.7
  • 137
    • 35448940523 scopus 로고    scopus 로고
    • Induction of preferential chemotaxis of unstimulated b-lymphocytes by 2-arachidonoylglycerol in immunized mice
    • Tanikawa T, Kurohane K, Imai Y. Induction of preferential chemotaxis of unstimulated B-lymphocytes by 2-arachidonoylglycerol in immunized mice. Microbiol Immunol 2007; 51:1013–9.
    • (2007) Microbiol Immunol , vol.51 , pp. 1013-1019
    • Tanikawa, T.1    Kurohane, K.2    Imai, Y.3


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