메뉴 건너뛰기




Volumn 90, Issue 5, 2011, Pages 983-995

Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection

Author keywords

Endocannabinoids; Host response; Immune homeostasis; Immune regulation; Lung; Pathology

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CYTOKINE; TRANSCRIPTOME;

EID: 80055070153     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0511219     Document Type: Article
Times cited : (32)

References (54)
  • 2
    • 1542343954 scopus 로고    scopus 로고
    • Shielding the double-edged sword: Negative regulation of the innate immune system
    • Kobayashi, K. S., Flavell, R. A. (2004) Shielding the double-edged sword: negative regulation of the innate immune system. J. Leukoc. Biol. 75, 428-433.
    • (2004) J. Leukoc. Biol , vol.75 , pp. 428-433
    • Kobayashi, K.S.1    Flavell, R.A.2
  • 3
    • 0037398404 scopus 로고    scopus 로고
    • Feedback regulation of pathogen-specific T cell priming
    • Wong, P., Pamer, E. G. (2003) Feedback regulation of pathogen-specific T cell priming. Immunity 18, 499-511.
    • (2003) Immunity , vol.18 , pp. 499-511
    • Wong, P.1    Pamer, E.G.2
  • 4
    • 0036196346 scopus 로고    scopus 로고
    • Cytokines in innate host defense in the lung
    • Strieter, R. M., Belperio, J. A., Keane, M. P. (2002) Cytokines in innate host defense in the lung. J. Clin. Invest. 109, 699-705.
    • (2002) J. Clin. Invest , vol.109 , pp. 699-705
    • Strieter, R.M.1    Belperio, J.A.2    Keane, M.P.3
  • 5
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., Steinman, R. M. (1998) Dendritic cells and the control of immunity. Nature 392, 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 6
    • 0030664401 scopus 로고    scopus 로고
    • Effector CD4+ and CD8+ T-cell mechanisms in the control of respiratory virus infections
    • Doherty, P. C., Topham, D. J., Tripp, R. A., Cardin, R. D., Brooks, J. W., Stevenson, P. G. (1997) Effector CD4+ and CD8+ T-cell mechanisms in the control of respiratory virus infections. Immunol. Rev. 159, 105-117.
    • (1997) Immunol. Rev , vol.159 , pp. 105-117
    • Doherty, P.C.1    Topham, D.J.2    Tripp, R.A.3    Cardin, R.D.4    Brooks, J.W.5    Stevenson, P.G.6
  • 7
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • Kolls, J. K., Linden, A. (2004) Interleukin-17 family members and inflammation. Immunity 21, 467-476.
    • (2004) Immunity , vol.21 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 12
    • 0035139418 scopus 로고    scopus 로고
    • Production of interferon-γ by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology
    • Wiley, J. A., Cerwenka, A., Harkema, J. R., Dutton, R. W., Harmsen, A. G. (2001) Production of interferon-γ by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology. Am. J. Pathol. 158, 119-130.
    • (2001) Am. J. Pathol , vol.158 , pp. 119-130
    • Wiley, J.A.1    Cerwenka, A.2    Harkema, J.R.3    Dutton, R.W.4    Harmsen, A.G.5
  • 13
    • 0031824006 scopus 로고    scopus 로고
    • Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model
    • Moskophidis, D., Kioussis, D. (1998) Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model. J. Exp. Med. 188, 223-232.
    • (1998) J. Exp. Med , vol.188 , pp. 223-232
    • Moskophidis, D.1    Kioussis, D.2
  • 14
    • 43249100162 scopus 로고    scopus 로고
    • Targeting the endocannabinoid system: To enhance or reduce?
    • Di Marzo, V. (2008) Targeting the endocannabinoid system: to enhance or reduce? Nat. Rev. Drug Discov. 7, 438-455.
    • (2008) Nat. Rev. Drug Discov , vol.7 , pp. 438-455
    • di Marzo, V.1
  • 19
    • 43349095841 scopus 로고    scopus 로고
    • Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/ 8/34 in the absence and presence of {increment}9-tetrahydrocannabinol
    • Buchweitz, J. P., Karmaus, P. W., Williams, K. J., Harkema, J. R., Kaminski, N. E. (2008) Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/ 8/34 in the absence and presence of {increment}9-tetrahydrocannabinol. J. Leukoc. Biol. 83, 785-796.
    • (2008) J. Leukoc. Biol , vol.83 , pp. 785-796
    • Buchweitz, J.P.1    Karmaus, P.W.2    Williams, K.J.3    Harkema, J.R.4    Kaminski, N.E.5
  • 20
    • 70249096341 scopus 로고    scopus 로고
    • IL-17 and IFN-γ mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responses
    • He, D., Wu, L., Kim, H. K., Li, H., Elmets, C. A., Xu, H. (2009) IL-17 and IFN-γ mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responses. J. Immunol. 183, 1463-1470.
    • (2009) J. Immunol , vol.183 , pp. 1463-1470
    • He, D.1    Wu, L.2    Kim, H.K.3    Li, H.4    Elmets, C.A.5    Xu, H.6
  • 21
    • 0026703488 scopus 로고
    • A kinetic study of immune mediators in the lungs of mice infected with influenza A virus
    • Hennet, T., Ziltener, H. J., Frei, K., Peterhans, E. (1992) A kinetic study of immune mediators in the lungs of mice infected with influenza A virus. J. Immunol. 149, 932-939.
    • (1992) J. Immunol , vol.149 , pp. 932-939
    • Hennet, T.1    Ziltener, H.J.2    Frei, K.3    Peterhans, E.4
  • 22
    • 77952470424 scopus 로고    scopus 로고
    • The effects of targeted deletion of cannabinoid receptors CB1 and CB2 on intranasal sensitization and challenge with adjuvant-free ovalbumin
    • Kaplan, B. L., Lawver, J. E., Karmaus, P. W., Ngaotepprutaram, T., Birmingham, N. P., Harkema, J. R., Kaminski, N. E. (2010) The effects of targeted deletion of cannabinoid receptors CB1 and CB2 on intranasal sensitization and challenge with adjuvant-free ovalbumin. Toxicol. Pathol. 38, 382-392.
    • (2010) Toxicol. Pathol , vol.38 , pp. 382-392
    • Kaplan, B.L.1    Lawver, J.E.2    Karmaus, P.W.3    Ngaotepprutaram, T.4    Birmingham, N.P.5    Harkema, J.R.6    Kaminski, N.E.7
  • 24
    • 0033012030 scopus 로고    scopus 로고
    • An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
    • Lutz, M. B., Kukutsch, N., Ogilvie, A. L., Rossner, S., Koch, F., Romani, N., Schuler, G. (1999) An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223, 77-92.
    • (1999) J. Immunol. Methods , vol.223 , pp. 77-92
    • Lutz, M.B.1    Kukutsch, N.2    Ogilvie, A.L.3    Rossner, S.4    Koch, F.5    Romani, N.6    Schuler, G.7
  • 25
    • 0345257344 scopus 로고    scopus 로고
    • Interleukin-21 inhibits dendritic cell activation and maturation
    • Brandt, K., Bulfone-Paus, S., Foster, D. C., Ruckert, R. (2003) Interleukin-21 inhibits dendritic cell activation and maturation. Blood 102, 4090-4098.
    • (2003) Blood , vol.102 , pp. 4090-4098
    • Brandt, K.1    Bulfone-Paus, S.2    Foster, D.C.3    Ruckert, R.4
  • 26
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells
    • Ivanov, I. I., McKenzie, B. S., Zhou, L., Tadokoro, C. E., Lepelley, A., Lafaille, J. J., Cua, D. J., Littman, D. R. (2006) The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126, 1121-1133.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6    Cua, D.J.7    Littman, D.R.8
  • 28
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira, S., Uematsu, S., Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 124, 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 29
    • 57149109403 scopus 로고    scopus 로고
    • Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivity to immune modulation by {increment}9-tetrahydrocannabinol
    • Springs, A. E., Karmaus, P. W., Crawford, R. B., Kaplan, B. L., Kaminski, N. E. (2008) Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivity to immune modulation by {increment}9-tetrahydrocannabinol. J. Leukoc. Biol. 84, 1574-1584.
    • (2008) J. Leukoc. Biol , vol.84 , pp. 1574-1584
    • Springs, A.E.1    Karmaus, P.W.2    Crawford, R.B.3    Kaplan, B.L.4    Kaminski, N.E.5
  • 33
    • 33344468233 scopus 로고    scopus 로고
    • Neutrophils and immunity: Challenges and opportunities
    • Nathan, C. (2006) Neutrophils and immunity: challenges and opportunities. Nat. Rev. Immunol. 6, 173-182.
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 173-182
    • Nathan, C.1
  • 34
    • 0037771294 scopus 로고    scopus 로고
    • Clara cell secretory protein modulates lung inflammatory and immune responses to respiratory syncytial virus infection
    • Wang, S. Z., Rosenberger, C. L., Bao, Y. X., Stark, J. M., Harrod, K. S. (2003) Clara cell secretory protein modulates lung inflammatory and immune responses to respiratory syncytial virus infection. J. Immunol. 171, 1051-1060.
    • (2003) J. Immunol , vol.171 , pp. 1051-1060
    • Wang, S.Z.1    Rosenberger, C.L.2    Bao, Y.X.3    Stark, J.M.4    Harrod, K.S.5
  • 35
    • 16844366717 scopus 로고    scopus 로고
    • CD38 is expressed selectively during the activation of a subset of mature T cells with reduced proliferation but improved potential to produce cytokines
    • Sandoval-Montes, C., Santos-Argumedo, L. (2005) CD38 is expressed selectively during the activation of a subset of mature T cells with reduced proliferation but improved potential to produce cytokines. J. Leukoc. Biol. 77, 513-521.
    • (2005) J. Leukoc. Biol , vol.77 , pp. 513-521
    • Sandoval-Montes, C.1    Santos-Argumedo, L.2
  • 36
    • 46949088224 scopus 로고    scopus 로고
    • Both Th1 and Th17 are immunopathogenic but differ in other key biological activities
    • Cox, C. A., Shi, G., Yin, H., Vistica, B. P., Wawrousek, E. F., Chan, C. C., Gery, I. (2008) Both Th1 and Th17 are immunopathogenic but differ in other key biological activities. J. Immunol. 180, 7414-7422.
    • (2008) J. Immunol , vol.180 , pp. 7414-7422
    • Cox, C.A.1    Shi, G.2    Yin, H.3    Vistica, B.P.4    Wawrousek, E.F.5    Chan, C.C.6    Gery, I.7
  • 37
    • 64849107608 scopus 로고    scopus 로고
    • NF-κ B1 p105 regulates T cell homeostasis and prevents chronic inflammation
    • Chang, M., Lee, A. J., Fitzpatrick, L., Zhang, M., Sun, S. C. (2009) NF-κ B1 p105 regulates T cell homeostasis and prevents chronic inflammation. J. Immunol. 182, 3131-3138.
    • (2009) J. Immunol , vol.182 , pp. 3131-3138
    • Chang, M.1    Lee, A.J.2    Fitzpatrick, L.3    Zhang, M.4    Sun, S.C.5
  • 38
    • 15944395145 scopus 로고    scopus 로고
    • Insights into host responses against pathogens from transcriptional profiling
    • Jenner, R. G., Young, R. A. (2005) Insights into host responses against pathogens from transcriptional profiling. Nat. Rev. Microbiol. 3, 281-294.
    • (2005) Nat. Rev. Microbiol , vol.3 , pp. 281-294
    • Jenner, R.G.1    Young, R.A.2
  • 39
    • 0037926880 scopus 로고    scopus 로고
    • Cytokine-mediated regulation of iron transport in human monocytic cells
    • Ludwiczek, S., Aigner, E., Theurl, I., Weiss, G. (2003) Cytokine-mediated regulation of iron transport in human monocytic cells. Blood 101, 4148-4154.
    • (2003) Blood , vol.101 , pp. 4148-4154
    • Ludwiczek, S.1    Aigner, E.2    Theurl, I.3    Weiss, G.4
  • 40
    • 0034089867 scopus 로고    scopus 로고
    • Effects of interferon-γ and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2
    • Kim, S., Ponka, P. (2000) Effects of interferon-γ and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2. J. Biol. Chem. 275, 6220-6226.
    • (2000) J. Biol. Chem , vol.275 , pp. 6220-6226
    • Kim, S.1    Ponka, P.2
  • 41
    • 0028979327 scopus 로고
    • {increment}9-Tetrahydrocannabinol modulates antigen processing by macrophages
    • McCoy, K. L., Gainey, D., Cabral, G. A. (1995) {increment}9-Tetrahydrocannabinol modulates antigen processing by macrophages. J. Pharmacol. Exp. Ther. 273, 1216-1223.
    • (1995) J. Pharmacol. Exp. Ther , vol.273 , pp. 1216-1223
    • McCoy, K.L.1    Gainey, D.2    Cabral, G.A.3
  • 42
    • 0033057247 scopus 로고    scopus 로고
    • Cannabinoid inhibition of the processing of intact lysozyme by macrophages: Evidence for CB2 receptor participation
    • McCoy, K. L., Matveyeva, M., Carlisle, S. J., Cabral, G. A. (1999) Cannabinoid inhibition of the processing of intact lysozyme by macrophages: evidence for CB2 receptor participation. J. Pharmacol. Exp. Ther. 289, 1620-1625.
    • (1999) J. Pharmacol. Exp. Ther , vol.289 , pp. 1620-1625
    • McCoy, K.L.1    Matveyeva, M.2    Carlisle, S.J.3    Cabral, G.A.4
  • 43
    • 0034685707 scopus 로고    scopus 로고
    • Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor
    • Buckley, N. E., McCoy, K. L., Mezey, E., Bonner, T., Zimmer, A., Felder, C. C., Glass, M. (2000) Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor. Eur. J. Pharmacol. 396, 141-149.
    • (2000) Eur. J. Pharmacol , vol.396 , pp. 141-149
    • Buckley, N.E.1    McCoy, K.L.2    Mezey, E.3    Bonner, T.4    Zimmer, A.5    Felder, C.C.6    Glass, M.7
  • 45
    • 0032219490 scopus 로고    scopus 로고
    • {increment}9-Tetrahydrocannabinol suppresses macrophage costimulation by decreasing heat-stable antigen expression
    • Clements, D. J., Matveyeva, M., McCoy, K. L. (1998) {increment}9-Tetrahydrocannabinol suppresses macrophage costimulation by decreasing heat-stable antigen expression. Int. J. Immunopharmacol. 20, 415-428.
    • (1998) Int. J. Immunopharmacol , vol.20 , pp. 415-428
    • Clements, D.J.1    Matveyeva, M.2    McCoy, K.L.3
  • 46
    • 51549090440 scopus 로고    scopus 로고
    • Cannabinoids affect dendritic cell (DC) potassium channel function and modulate DC T cell stimulatory capacity
    • Wacnik, P. W., Luhr, K. M., Hill, R. H., Ljunggren, H. G., Kristensson, K., Svensson, M. (2008) Cannabinoids affect dendritic cell (DC) potassium channel function and modulate DC T cell stimulatory capacity. J. Immunol. 181, 3057-3066.
    • (2008) J. Immunol , vol.181 , pp. 3057-3066
    • Wacnik, P.W.1    Luhr, K.M.2    Hill, R.H.3    Ljunggren, H.G.4    Kristensson, K.5    Svensson, M.6
  • 48
    • 23744512890 scopus 로고    scopus 로고
    • Role of apoptosis and cytokines in influenza virus morbidity
    • Brydon, E. W., Morris, S. J., Sweet, C. (2005) Role of apoptosis and cytokines in influenza virus morbidity. FEMS Microbiol. Rev. 29, 837-850.
    • (2005) FEMS Microbiol. Rev , vol.29 , pp. 837-850
    • Brydon, E.W.1    Morris, S.J.2    Sweet, C.3
  • 49
    • 34250879032 scopus 로고    scopus 로고
    • Time-dependent airway epithelial and inflammatory cell responses induced by influenza virus A/PR/8/34 in C57BL/6 mice
    • Buchweitz, J. P., Harkema, J. R., Kaminski, N. E. (2007) Time-dependent airway epithelial and inflammatory cell responses induced by influenza virus A/PR/8/34 in C57BL/6 mice. Toxicol. Pathol. 35, 424-435.
    • (2007) Toxicol. Pathol , vol.35 , pp. 424-435
    • Buchweitz, J.P.1    Harkema, J.R.2    Kaminski, N.E.3
  • 50
    • 77949760982 scopus 로고    scopus 로고
    • The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease
    • Storr, M., Emmerdinger, D., Diegelmann, J., Pfennig, S., Ochsenkuhn, T., Goke, B., Lohse, P., Brand, S. (2010) The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease. PLoS ONE 5, e9453.
    • (2010) PLoS ONE , vol.5
    • Storr, M.1    Emmerdinger, D.2    Diegelmann, J.3    Pfennig, S.4    Ochsenkuhn, T.5    Goke, B.6    Lohse, P.7    Brand, S.8
  • 51
    • 22144477141 scopus 로고    scopus 로고
    • Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: Possible risk for autoimmune disorders
    • Sipe, J. C., Arbour, N., Gerber, A., Beutler, E. (2005) Reduced endocannabinoid immune modulation by a common cannabinoid 2 (CB2) receptor gene polymorphism: possible risk for autoimmune disorders. J. Leukoc. Biol. 78, 231-238.
    • (2005) J. Leukoc. Biol , vol.78 , pp. 231-238
    • Sipe, J.C.1    Arbour, N.2    Gerber, A.3    Beutler, E.4
  • 52
    • 30944434828 scopus 로고    scopus 로고
    • Increased number of mature dendritic cells in Crohn's disease: Evidence for a chemokine mediated retention mechanism
    • Middel, P., Raddatz, D., Gunawan, B., Haller, F., Radzun, H. J. (2006) Increased number of mature dendritic cells in Crohn's disease: evidence for a chemokine mediated retention mechanism. Gut 55, 220-227.
    • (2006) Gut , vol.55 , pp. 220-227
    • Middel, P.1    Raddatz, D.2    Gunawan, B.3    Haller, F.4    Radzun, H.J.5
  • 53
    • 0033636254 scopus 로고    scopus 로고
    • Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis
    • Serafini, B., Columba-Cabezas, S., Di Rosa, F., Aloisi, F. (2000) Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis. Am. J. Pathol. 157, 1991-2002.
    • (2000) Am. J. Pathol , vol.157 , pp. 1991-2002
    • Serafini, B.1    Columba-Cabezas, S.2    di Rosa, F.3    Aloisi, F.4
  • 54
    • 0032547818 scopus 로고    scopus 로고
    • Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue
    • Ludewig, B., Odermatt, B., Landmann, S., Hengartner, H., Zinkernagel, R. M. (1998) Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue. J. Exp. Med. 188, 1493-1501.
    • (1998) J. Exp. Med , vol.188 , pp. 1493-1501
    • Ludewig, B.1    Odermatt, B.2    Landmann, S.3    Hengartner, H.4    Zinkernagel, R.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.