The endocannabinoid 2-arachidonoyl-glycerol activates human neutrophils: Critical role of its hydrolysis and de novo leukotriene B4 biosynthesis

Journal of Immunology

Volumn 186, Issue 5, 2011, Pages 3188-3196

  Chouinard, François ^a,b   Lefebvre, Julie S ^c   Navarro, Pauline ^a,b   Bouchard, Line ^a,b   Ferland, Claudine ^a,b   Lalancette Hébert, Mélanie ^d   Marsolais, David ^a,b   Laviolette, Michel ^a,b   Flamand, Nicolas ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

^c TRUDEAU INSTITUTE   (United States)

^d Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; ARACHIDONIC ACID; ENDOCANNABINOID; LEUKOTRIENE B4; MYELOPEROXIDASE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM MOBILIZATION; CELL ACTIVATION; CELL ACTIVITY; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; DRUG HYDROLYSIS; ENZYME ACTIVATION; ENZYME RELEASE; FATTY ACID SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOMODULATION; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACID; ARACHIDONIC ACIDS; CELL DEGRANULATION; ENDOCANNABINOIDS; GLYCERIDES; HUMANS; HYDROLYSIS; LEUKOTRIENE B4; NEUTROPHIL ACTIVATION; NEUTROPHILS;

EID: 79952751764     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002853     Document Type: Article

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