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Volumn 1, Issue 4, 2014, Pages 118-127

Longevity pathways and maintenance of the proteome: The role of autophagy and mitophagy during yeast ageing

Author keywords

Ageing; Autophagy; Chronological lifespan; Mitophagy; Nutrient sensing pathways; Replicative lifespan; Yeast

Indexed keywords


EID: 84997675675     PISSN: None     EISSN: 23112638     Source Type: Journal    
DOI: 10.15698/mic2014.01.136     Document Type: Review
Times cited : (25)

References (99)
  • 1
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span--from yeast to humans
    • Fontana L, Partridge L, Longo VD (2010). Extending healthy life span--from yeast to humans. Science 328(5976): 321-326.
    • (2010) Science , vol.328 , Issue.5976 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 2
    • 77950214581 scopus 로고    scopus 로고
    • Lessons on longevity from budding yeast
    • Kaeberlein M (2010). Lessons on longevity from budding yeast. Nature 464(7288): 513-519.
    • (2010) Nature , vol.464 , Issue.7288 , pp. 513-519
    • Kaeberlein, M.1
  • 3
    • 84863524526 scopus 로고    scopus 로고
    • Replicative and chronological aging in Saccharomyces cerevisiae
    • Longo VD, Shadel GS, Kaeberlein M, Kennedy B (2012). Replicative and chronological aging in Saccharomyces cerevisiae. Cell metabolism 16(1): 18-31.
    • (2012) Cell Metabolism , vol.16 , Issue.1 , pp. 18-31
    • Longo, V.D.1    Shadel, G.S.2    Kaeberlein, M.3    Kennedy, B.4
  • 4
    • 33645111650 scopus 로고    scopus 로고
    • Long-lived yeast as a model for ageing research
    • Piper PW (2006). Long-lived yeast as a model for ageing research. Yeast 23(3): 215-226.
    • (2006) Yeast , vol.23 , Issue.3 , pp. 215-226
    • Piper, P.W.1
  • 5
    • 0035853552 scopus 로고    scopus 로고
    • Regulation of longevity and stress resistance by Sch9 in yeast
    • Fabrizio P, Pozza F, Pletcher SD, Gendron CM, Longo VD (2001). Regulation of longevity and stress resistance by Sch9 in yeast. Science 292(5515): 288-290.
    • (2001) Science , vol.292 , Issue.5515 , pp. 288-290
    • Fabrizio, P.1    Pozza, F.2    Pletcher, S.D.3    Gendron, C.M.4    Longo, V.D.5
  • 7
    • 0034703217 scopus 로고    scopus 로고
    • Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
    • Lin SJ, Defossez PA, Guarente L (2000). Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289(5487): 2126-2128.
    • (2000) Science , vol.289 , Issue.5487 , pp. 2126-2128
    • Lin, S.J.1    Defossez, P.A.2    Guarente, L.3
  • 8
    • 0038687689 scopus 로고    scopus 로고
    • The Ras and Sch9 pathways regulate stress resistance and longevity
    • Longo VD (2003). The Ras and Sch9 pathways regulate stress resistance and longevity. Experimental gerontology 38(7): 807-811.
    • (2003) Experimental Gerontology , vol.38 , Issue.7 , pp. 807-811
    • Longo, V.D.1
  • 9
  • 10
    • 67149130284 scopus 로고    scopus 로고
    • Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension
    • Wei M, Fabrizio P, Madia F, Hu J, Ge H, Li LM, Longo VD (2009). Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. PLoS genetics 5(5): e1000467.
    • (2009) Plos Genetics , vol.5 , Issue.5
    • Wei, M.1    Fabrizio, P.2    Madia, F.3    Hu, J.4    Ge, H.5    Li, L.M.6    Longo, V.D.7
  • 11
    • 20744432592 scopus 로고    scopus 로고
    • The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9
    • Liu K, Zhang X, Lester RL, Dickson RC (2005). The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9. The Journal of biological chemistry 280(24): 22679-22687.
    • (2005) The Journal of Biological Chemistry , vol.280 , Issue.24 , pp. 22679-22687
    • Liu, K.1    Zhang, X.2    Lester, R.L.3    Dickson, R.C.4
  • 12
    • 84859166169 scopus 로고    scopus 로고
    • Down-regulating sphingolipid synthesis increases yeast lifespan
    • Huang X, Liu J, Dickson RC (2012). Down-regulating sphingolipid synthesis increases yeast lifespan. PLoS genetics 8(2): e1002493.
    • (2012) Plos Genetics , vol.8 , Issue.2
    • Huang, X.1    Liu, J.2    Dickson, R.C.3
  • 15
    • 35648995939 scopus 로고    scopus 로고
    • MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae
    • Medvedik O, Lamming DW, Kim KD, Sinclair DA (2007). MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLoS biology 5(10): e261.
    • (2007) Plos Biology , vol.5 , Issue.10
    • Medvedik, O.1    Lamming, D.W.2    Kim, K.D.3    Sinclair, D.A.4
  • 19
    • 38949137849 scopus 로고    scopus 로고
    • Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
    • Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L, Longo VD (2008). Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9. PLoS genetics 4(1): e13.
    • (2008) Plos Genetics , vol.4 , Issue.1
    • Wei, M.1    Fabrizio, P.2    Hu, J.3    Ge, H.4    Cheng, C.5    Li, L.6    Longo, V.D.7
  • 20
    • 79954541644 scopus 로고    scopus 로고
    • Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence
    • Weinberger M, Mesquita A, Caroll T, Marks L, Yang H, Zhang Z, Ludovico P, Burhans WC (2010). Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence. Aging (Albany NY) 2(10): 709-726.
    • (2010) Aging (Albany NY) , vol.2 , Issue.10 , pp. 709-726
    • Weinberger, M.1    Mesquita, A.2    Caroll, T.3    Marks, L.4    Yang, H.5    Zhang, Z.6    Ludovico, P.7    Burhans, W.C.8
  • 21
    • 68049109688 scopus 로고    scopus 로고
    • Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density
    • Pan Y, Shadel GS (2009). Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density. Aging (Albany NY) 1(1): 131-145.
    • (2009) Aging (Albany NY) , vol.1 , Issue.1 , pp. 131-145
    • Pan, Y.1    Shadel, G.S.2
  • 22
    • 33947574775 scopus 로고    scopus 로고
    • Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression
    • Bonawitz ND, Chatenay-Lapointe M, Pan Y, Shadel GS (2007). Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression. Cell metabolism 5(4): 265-277.
    • (2007) Cell Metabolism , vol.5 , Issue.4 , pp. 265-277
    • Bonawitz, N.D.1    Chatenay-Lapointe, M.2    Pan, Y.3    Shadel, G.S.4
  • 24
    • 79958068191 scopus 로고    scopus 로고
    • Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling
    • Pan Y, Schroeder EA, Ocampo A, Barrientos A, Shadel GS (2011). Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling. Cell metabolism 13(6): 668-678.
    • (2011) Cell Metabolism , vol.13 , Issue.6 , pp. 668-678
    • Pan, Y.1    Schroeder, E.A.2    Ocampo, A.3    Barrientos, A.4    Shadel, G.S.5
  • 25
    • 84863527085 scopus 로고    scopus 로고
    • Mitochondrial respiratory thresholds regulate yeast chronological life span and its extension by caloric restriction
    • Ocampo A, Liu J, Schroeder EA, Shadel GS, Barrientos A (2012). Mitochondrial respiratory thresholds regulate yeast chronological life span and its extension by caloric restriction. Cell metabolism 16(1): 55-67.
    • (2012) Cell Metabolism , vol.16 , Issue.1 , pp. 55-67
    • Ocampo, A.1    Liu, J.2    Schroeder, E.A.3    Shadel, G.S.4    Barrientos, A.5
  • 26
    • 47049116691 scopus 로고    scopus 로고
    • Increased respiration in the sch9Delta mutant is required for increasing chronological life span but not replicative life span
    • Lavoie H, Whiteway M (2008). Increased respiration in the sch9Delta mutant is required for increasing chronological life span but not replicative life span. Eukaryotic cell 7(7): 1127-1135.
    • (2008) Eukaryotic Cell , vol.7 , Issue.7 , pp. 1127-1135
    • Lavoie, H.1    Whiteway, M.2
  • 28
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D (1956). Aging: a theory based on free radical and radiation chemistry. J Gerontol 11(3): 298-300.
    • (1956) J Gerontol , vol.11 , Issue.3 , pp. 298-300
    • Harman, D.1
  • 29
    • 84893764052 scopus 로고    scopus 로고
    • Reactive oxygen species, ageing and the hormesis police
    • Ludovico P, Burhans WC (2013). Reactive oxygen species, ageing and the hormesis police. FEMS yeast research 14(1): 33–39.
    • (2013) FEMS Yeast Research , vol.14 , Issue.1 , pp. 33-39
    • Ludovico, P.1    Burhans, W.C.2
  • 30
    • 84878797603 scopus 로고    scopus 로고
    • Epigenetic silencing mediates mitochondria stress-induced longevity
    • Schroeder EA, Raimundo N, Shadel GS (2013). Epigenetic silencing mediates mitochondria stress-induced longevity. Cell metabolism 17(6): 954-964.
    • (2013) Cell Metabolism , vol.17 , Issue.6 , pp. 954-964
    • Schroeder, E.A.1    Raimundo, N.2    Shadel, G.S.3
  • 32
    • 0033529926 scopus 로고    scopus 로고
    • Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae
    • Ashrafi K, Sinclair D, Gordon JI, Guarente L (1999). Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(16): 9100-9105.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.16 , pp. 9100-9105
    • Ashrafi, K.1    Sinclair, D.2    Gordon, J.I.3    Guarente, L.4
  • 33
    • 33746880713 scopus 로고    scopus 로고
    • Preadaptation to efficient respiratory maintenance is essential both for maximal longevity and the retention of replicative potential in chronologically ageing yeast
    • Piper PW, Harris NL, MacLean M (2006). Preadaptation to efficient respiratory maintenance is essential both for maximal longevity and the retention of replicative potential in chronologically ageing yeast. Mechanisms of ageing and development 127(9): 733-740.
    • (2006) Mechanisms of Ageing and Development , vol.127 , Issue.9 , pp. 733-740
    • Piper, P.W.1    Harris, N.L.2    Maclean, M.3
  • 35
    • 77953594906 scopus 로고    scopus 로고
    • Snf1/AMPK promotes S-phase entrance by controlling CLB5 transcription in budding yeast
    • Pessina S, Tsiarentsyeva V, Busnelli S, Vanoni M, Alberghina L, Coccetti P (2010). Snf1/AMPK promotes S-phase entrance by controlling CLB5 transcription in budding yeast. Cell cycle 9(11): 2189-2200.
    • (2010) Cell Cycle , vol.9 , Issue.11 , pp. 2189-2200
    • Pessina, S.1    Tsiarentsyeva, V.2    Busnelli, S.3    Vanoni, M.4    Alberghina, L.5    Coccetti, P.6
  • 36
    • 1642602693 scopus 로고    scopus 로고
    • The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression
    • Searle JS, Schollaert KL, Wilkins BJ, Sanchez Y (2004). The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression. Nat Cell Biol 6(2): 138-145.
    • (2004) Nat Cell Biol , vol.6 , Issue.2 , pp. 138-145
    • Searle, J.S.1    Schollaert, K.L.2    Wilkins, B.J.3    Sanchez, Y.4
  • 37
    • 84856104730 scopus 로고    scopus 로고
    • Nutritional stress in eukaryotic cells: Oxidative species and regulation of survival in time of scarceness
    • Ferretti AC, Larocca MC, Favre C (2012). Nutritional stress in eukaryotic cells: oxidative species and regulation of survival in time of scarceness. Mol Genet Metab 105(2): 186-192.
    • (2012) Mol Genet Metab , vol.105 , Issue.2 , pp. 186-192
    • Ferretti, A.C.1    Larocca, M.C.2    Favre, C.3
  • 38
    • 33751191872 scopus 로고    scopus 로고
    • Nitrogen availability and TOR regulate the Snf1 protein kinase in Saccharomyces cerevisiae
    • Orlova M, Kanter E, Krakovich D, Kuchin S (2006). Nitrogen availability and TOR regulate the Snf1 protein kinase in Saccharomyces cerevisiae. Eukaryotic cell 5(11): 1831-1837.
    • (2006) Eukaryotic Cell , vol.5 , Issue.11 , pp. 1831-1837
    • Orlova, M.1    Kanter, E.2    Krakovich, D.3    Kuchin, S.4
  • 39
    • 0033870805 scopus 로고    scopus 로고
    • Sip2p and its partner snf1p kinase affect aging in S. Cerevisiae
    • Ashrafi K, Lin SS, Manchester JK, Gordon JI (2000). Sip2p and its partner snf1p kinase affect aging in S. cerevisiae. Genes & development 14(15): 1872-1885.
    • (2000) Genes & Development , vol.14 , Issue.15 , pp. 1872-1885
    • Ashrafi, K.1    Lin, S.S.2    Manchester, J.K.3    Gordon, J.I.4
  • 40
    • 38449110592 scopus 로고    scopus 로고
    • SNF1/AMPK pathways in yeast
    • Hedbacker K, Carlson M (2008). SNF1/AMPK pathways in yeast. Front Biosci 13(2408-2420.
    • (2008) Front Biosci , vol.13 , pp. 2408-2420
    • Hedbacker, K.1    Carlson, M.2
  • 41
    • 0038644946 scopus 로고    scopus 로고
    • Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing
    • Lin SS, Manchester JK, Gordon JI (2003). Sip2, an N-myristoylated beta subunit of Snf1 kinase, regulates aging in Saccharomyces cerevisiae by affecting cellular histone kinase activity, recombination at rDNA loci, and silencing. The Journal of biological chemistry 278(15): 13390-13397.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.15 , pp. 13390-13397
    • Lin, S.S.1    Manchester, J.K.2    Gordon, J.I.3
  • 42
    • 0034626747 scopus 로고    scopus 로고
    • Genetic pathways that regulate ageing in model organisms
    • Guarente L, Kenyon C (2000). Genetic pathways that regulate ageing in model organisms. Nature 408(6809): 255-262.
    • (2000) Nature , vol.408 , Issue.6809 , pp. 255-262
    • Guarente, L.1    Kenyon, C.2
  • 45
    • 0034898851 scopus 로고    scopus 로고
    • Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p
    • Wang Z, Wilson WA, Fujino MA, Roach PJ (2001). Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p. Mol Cell Biol 21(17): 5742-5752.
    • (2001) Mol Cell Biol , vol.21 , Issue.17 , pp. 5742-5752
    • Wang, Z.1    Wilson, W.A.2    Fujino, M.A.3    Roach, P.J.4
  • 46
    • 0025021673 scopus 로고
    • Release of two Saccharomyces cerevisiae cytochrome genes, COX6 and CYC1, from glucose repression requires the SNF1 and SSN6 gene products
    • Wright RM, Poyton RO (1990). Release of two Saccharomyces cerevisiae cytochrome genes, COX6 and CYC1, from glucose repression requires the SNF1 and SSN6 gene products. Mol Cell Biol 10(3): 1297-1300.
    • (1990) Mol Cell Biol , vol.10 , Issue.3 , pp. 1297-1300
    • Wright, R.M.1    Poyton, R.O.2
  • 47
    • 79952455618 scopus 로고    scopus 로고
    • TOR signaling never gets old: Aging, longevity and TORC1 activity
    • Evans DS, Kapahi P, Hsueh WC, Kockel L (2011). TOR signaling never gets old: aging, longevity and TORC1 activity. Ageing research reviews 10(2): 225-237.
    • (2011) Ageing Research Reviews , vol.10 , Issue.2 , pp. 225-237
    • Evans, D.S.1    Kapahi, P.2    Hsueh, W.C.3    Kockel, L.4
  • 48
    • 79951787452 scopus 로고    scopus 로고
    • Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB
    • Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A (2011). Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature 470(7334): 404-408.
    • (2011) Nature , vol.470 , Issue.7334 , pp. 404-408
    • Mair, W.1    Morantte, I.2    Rodrigues, A.P.3    Manning, G.4    Montminy, M.5    Shaw, R.J.6    Dillin, A.7
  • 49
    • 74049134984 scopus 로고    scopus 로고
    • Oxaloacetate supplementation increases lifespan in Caenorhabditis elegans through an AMPK/FOXO-dependent pathway
    • Williams DS, Cash A, Hamadani L, Diemer T (2009). Oxaloacetate supplementation increases lifespan in Caenorhabditis elegans through an AMPK/FOXO-dependent pathway. Aging cell 8(6): 765-768.
    • (2009) Aging Cell , vol.8 , Issue.6 , pp. 765-768
    • Williams, D.S.1    Cash, A.2    Hamadani, L.3    Diemer, T.4
  • 50
    • 0033214237 scopus 로고    scopus 로고
    • The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms
    • Kaeberlein M, McVey M, Guarente L (1999). The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes & development 13(19): 2570-2580.
    • (1999) Genes & Development , vol.13 , Issue.19 , pp. 2570-2580
    • Kaeberlein, M.1    McVey, M.2    Guarente, L.3
  • 51
    • 0347128279 scopus 로고    scopus 로고
    • Calorie restriction extends yeast life span by lowering the level of NADH
    • Lin SJ, Ford E, Haigis M, Liszt G, Guarente L (2004). Calorie restriction extends yeast life span by lowering the level of NADH. Genes & development 18(1): 12-16.
    • (2004) Genes & Development , vol.18 , Issue.1 , pp. 12-16
    • Lin, S.J.1    Ford, E.2    Haigis, M.3    Liszt, G.4    Guarente, L.5
  • 52
    • 0038329323 scopus 로고    scopus 로고
    • Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
    • Anderson RM, Bitterman KJ, Wood JG, Medvedik O, Sinclair DA (2003). Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423(6936): 181-185.
    • (2003) Nature , vol.423 , Issue.6936 , pp. 181-185
    • Anderson, R.M.1    Bitterman, K.J.2    Wood, J.G.3    Medvedik, O.4    Sinclair, D.A.5
  • 53
    • 84893760820 scopus 로고    scopus 로고
    • Yeast sirtuins and the regulation of aging
    • Wierman MB, Smith JS (2013). Yeast sirtuins and the regulation of aging. FEMS yeast research 14(1): 73–88.
    • (2013) FEMS Yeast Research , vol.14 , Issue.1 , pp. 73-88
    • Wierman, M.B.1    Smith, J.S.2
  • 54
    • 34548615053 scopus 로고    scopus 로고
    • Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins
    • Smith DL, Jr., McClure JM, Matecic M, Smith JS (2007). Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins. Aging cell 6(5): 649-662.
    • (2007) Aging Cell , vol.6 , Issue.5 , pp. 649-662
    • Smith, D.L.1    McClure, J.M.2    Matecic, M.3    Smith, J.S.4
  • 63
    • 79960652801 scopus 로고    scopus 로고
    • Molecular chaperones in protein folding and proteostasis
    • Hartl FU, Bracher A, Hayer-Hartl M (2011). Molecular chaperones in protein folding and proteostasis. Nature 475(7356): 324-332.
    • (2011) Nature , vol.475 , Issue.7356 , pp. 324-332
    • Hartl, F.U.1    Bracher, A.2    Hayer-Hartl, M.3
  • 64
    • 79251498807 scopus 로고    scopus 로고
    • Protein homeostasis and aging: The importance of exquisite quality control
    • Koga H, Kaushik S, Cuervo AM (2011). Protein homeostasis and aging: The importance of exquisite quality control. Ageing research reviews 10(2): 205-215.
    • (2011) Ageing Research Reviews , vol.10 , Issue.2 , pp. 205-215
    • Koga, H.1    Kaushik, S.2    Cuervo, A.M.3
  • 65
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM, Klionsky DJ (2008). Autophagy fights disease through cellular self-digestion. Nature 451(7182): 1069-1075.
    • (2008) Nature , vol.451 , Issue.7182 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 67
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • Klionsky DJ, Emr SD (2000). Autophagy as a regulated pathway of cellular degradation. Science 290(5497): 1717-1721.
    • (2000) Science , vol.290 , Issue.5497 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 68
    • 0032512636 scopus 로고    scopus 로고
    • Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast
    • Noda T, Ohsumi Y (1998). Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. The Journal of biological chemistry 273(7): 3963-3966.
    • (1998) The Journal of Biological Chemistry , vol.273 , Issue.7 , pp. 3963-3966
    • Noda, T.1    Ohsumi, Y.2
  • 69
    • 0032847274 scopus 로고    scopus 로고
    • TOR kinase homologs function in a signal transduction pathway that is conserved from yeast to mammals
    • Cutler NS, Heitman J, Cardenas ME (1999). TOR kinase homologs function in a signal transduction pathway that is conserved from yeast to mammals. Mol Cell Endocrinol 155(1-2): 135-142.
    • (1999) Mol Cell Endocrinol , vol.155 , Issue.1-2 , pp. 135-142
    • Cutler, N.S.1    Heitman, J.2    Cardenas, M.E.3
  • 70
    • 67650237693 scopus 로고    scopus 로고
    • Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy
    • Yorimitsu T, He C, Wang K, Klionsky DJ (2009). Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy. Autophagy 5(5): 616-624.
    • (2009) Autophagy , vol.5 , Issue.5 , pp. 616-624
    • Yorimitsu, T.1    He, C.2    Wang, K.3    Klionsky, D.J.4
  • 71
    • 25444459688 scopus 로고    scopus 로고
    • An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase
    • Budovskaya YV, Stephan JS, Deminoff SJ, Herman PK (2005). An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase. Proc Natl Acad Sci U S A 102(39): 13933-13938.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.39 , pp. 13933-13938
    • Budovskaya, Y.V.1    Stephan, J.S.2    Deminoff, S.J.3    Herman, P.K.4
  • 73
    • 72549095406 scopus 로고    scopus 로고
    • Regulation mechanisms and signaling pathways of autophagy
    • He C, Klionsky DJ (2009). Regulation mechanisms and signaling pathways of autophagy. Annual review of genetics 43:67-93.
    • (2009) Annual Review of Genetics , vol.43 , pp. 67-93
    • He, C.1    Klionsky, D.J.2
  • 74
    • 34948828483 scopus 로고    scopus 로고
    • Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae
    • Yorimitsu T, Zaman S, Broach JR, Klionsky DJ (2007). Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae. Molecular biology of the cell 18(10): 4180-4189.
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.10 , pp. 4180-4189
    • Yorimitsu, T.1    Zaman, S.2    Broach, J.R.3    Klionsky, D.J.4
  • 75
    • 69349096593 scopus 로고    scopus 로고
    • Regulation of autophagy in yeast Saccharomyces cerevisiae
    • Cebollero E, Reggiori F (2009). Regulation of autophagy in yeast Saccharomyces cerevisiae. Biochimica et biophysica acta 1793(9): 1413-1421.
    • (2009) Biochimica Et Biophysica Acta , vol.1793 , Issue.9 , pp. 1413-1421
    • Cebollero, E.1    Reggiori, F.2
  • 76
    • 67651162109 scopus 로고    scopus 로고
    • Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae
    • Alvers AL, Fishwick LK, Wood MS, Hu D, Chung HS, Dunn WA, Jr., Aris JP (2009). Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae. Aging cell 8(4): 353-369.
    • (2009) Aging Cell , vol.8 , Issue.4 , pp. 353-369
    • Alvers, A.L.1    Fishwick, L.K.2    Wood, M.S.3    Hu, D.4    Chung, H.S.5    Dunn, W.A.6    Aris, J.P.7
  • 79
    • 78649289310 scopus 로고    scopus 로고
    • Endosomal protein sorting and autophagy genes contribute to the regulation of yeast life span
    • Longo VD, Nislow C, Fabrizio P (2010). Endosomal protein sorting and autophagy genes contribute to the regulation of yeast life span. Autophagy 6(8): 1227-1228.
    • (2010) Autophagy , vol.6 , Issue.8 , pp. 1227-1228
    • Longo, V.D.1    Nislow, C.2    Fabrizio, P.3
  • 80
    • 77957343158 scopus 로고    scopus 로고
    • Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation
    • Fabrizio P, Hoon S, Shamalnasab M, Galbani A, Wei M, Giaever G, Nislow C, Longo VD (2010). Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation. PLoS genetics 6(7): e1001024.
    • (2010) Plos Genetics , vol.6 , Issue.7
    • Fabrizio, P.1    Hoon, S.2    Shamalnasab, M.3    Galbani, A.4    Wei, M.5    Giaever, G.6    Nislow, C.7    Longo, V.D.8
  • 83
    • 78349275317 scopus 로고    scopus 로고
    • Mitophagy in yeast: Actors and physiological roles
    • Bhatia-Kissova I, Camougrand N (2010). Mitophagy in yeast: actors and physiological roles. FEMS yeast research 10(8): 1023-1034.
    • (2010) FEMS Yeast Research , vol.10 , Issue.8 , pp. 1023-1034
    • Bhatia-Kissova, I.1    Camougrand, N.2
  • 84
    • 84878562770 scopus 로고    scopus 로고
    • Autophagic processes in yeast: Mechanism, machinery and regulation
    • Reggiori F, Klionsky DJ (2013). Autophagic processes in yeast: mechanism, machinery and regulation. Genetics 194(2): 341-361.
    • (2013) Genetics , vol.194 , Issue.2 , pp. 341-361
    • Reggiori, F.1    Klionsky, D.J.2
  • 85
    • 75349112375 scopus 로고    scopus 로고
    • Mitochondrial turnover and aging of long-lived postmitotic cells: The mitochondrial-lysosomal axis theory of aging
    • Terman A, Kurz T, Navratil M, Arriaga EA, Brunk UT (2010). Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging. Antioxidants & redox signaling 12(4): 503-535.
    • (2010) Antioxidants & Redox Signaling , vol.12 , Issue.4 , pp. 503-535
    • Terman, A.1    Kurz, T.2    Navratil, M.3    Arriaga, E.A.4    Brunk, U.T.5
  • 86
    • 84862884156 scopus 로고    scopus 로고
    • Mitochondrial quality control: An integrated network of pathways
    • Fischer F, Hamann A, Osiewacz HD (2012). Mitochondrial quality control: an integrated network of pathways. Trends Biochem Sci 37(7): 284-292.
    • (2012) Trends Biochem Sci , vol.37 , Issue.7 , pp. 284-292
    • Fischer, F.1    Hamann, A.2    Osiewacz, H.D.3
  • 88
    • 67650246357 scopus 로고    scopus 로고
    • Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
    • Okamoto K, Kondo-Okamoto N, Ohsumi Y (2009). Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell 17(1): 87-97.
    • (2009) Dev Cell , vol.17 , Issue.1 , pp. 87-97
    • Okamoto, K.1    Kondo-Okamoto, N.2    Ohsumi, Y.3
  • 89
    • 67650264633 scopus 로고    scopus 로고
    • Atg32 is a mitochondrial protein that confers selectivity during mitophagy
    • Kanki T, Wang K, Cao Y, Baba M, Klionsky DJ (2009). Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Developmental cell 17(1): 98-109.
    • (2009) Developmental Cell , vol.17 , Issue.1 , pp. 98-109
    • Kanki, T.1    Wang, K.2    Cao, Y.3    Baba, M.4    Klionsky, D.J.5
  • 90
    • 80053379961 scopus 로고    scopus 로고
    • Mitophagy, mitochondrial dynamics and the general stress response in yeast
    • Muller M, Reichert AS (2011). Mitophagy, mitochondrial dynamics and the general stress response in yeast. Biochemical Society transactions 39(5): 1514-1519.
    • (2011) Biochemical Society Transactions , vol.39 , Issue.5 , pp. 1514-1519
    • Muller, M.1    Reichert, A.S.2
  • 91
    • 79953158981 scopus 로고    scopus 로고
    • Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2
    • Mendl N, Occhipinti A, Muller M, Wild P, Dikic I, Reichert AS (2011). Mitophagy in yeast is independent of mitochondrial fission and requires the stress response gene WHI2. Journal of cell science 124(Pt 8): 1339-1350.
    • (2011) Journal of Cell Science , vol.124 , pp. 1339-1350
    • Mendl, N.1    Occhipinti, A.2    Muller, M.3    Wild, P.4    Dikic, I.5    Reichert, A.S.6
  • 92
    • 0035998264 scopus 로고    scopus 로고
    • Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression
    • Kaida D, Yashiroda H, Toh-e A, Kikuchi Y (2002). Yeast Whi2 and Psr1-phosphatase form a complex and regulate STRE-mediated gene expression. Genes Cells 7(6): 543-552.
    • (2002) Genes Cells , vol.7 , Issue.6 , pp. 543-552
    • Kaida, D.1    Yashiroda, H.2    Toh-E, A.3    Kikuchi, Y.4
  • 95
    • 84871741160 scopus 로고    scopus 로고
    • The retrograde response: When mitochondrial quality control is not enough
    • Jazwinski SM (2013). The retrograde response: when mitochondrial quality control is not enough. Biochimica et biophysica acta 1833(2): 400-409.
    • (2013) Biochimica Et Biophysica Acta , vol.1833 , Issue.2 , pp. 400-409
    • Jazwinski, S.M.1
  • 96
    • 34247172582 scopus 로고    scopus 로고
    • Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival
    • Tal R, Winter G, Ecker N, Klionsky DJ, Abeliovich H (2007). Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival. The Journal of biological chemistry 282(8): 5617-5624.
    • (2007) The Journal of Biological Chemistry , vol.282 , Issue.8 , pp. 5617-5624
    • Tal, R.1    Winter, G.2    Ecker, N.3    Klionsky, D.J.4    Abeliovich, H.5
  • 98
    • 77953357982 scopus 로고    scopus 로고
    • Impaired quality control of mitochondria: Aging from a new perspective
    • Weber TA, Reichert AS (2010). Impaired quality control of mitochondria: aging from a new perspective. Experimental gerontology 45(7-8): 503-511.
    • (2010) Experimental Gerontology , vol.45 , Issue.7-8 , pp. 503-511
    • Weber, T.A.1    Reichert, A.S.2
  • 99
    • 79958219318 scopus 로고    scopus 로고
    • Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae
    • Mao K, Wang K, Zhao M, Xu T, Klionsky DJ (2011). Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae. The Journal of cell biology 193(4): 755-767.
    • (2011) The Journal of Cell Biology , vol.193 , Issue.4 , pp. 755-767
    • Mao, K.1    Wang, K.2    Zhao, M.3    Xu, T.4    Klionsky, D.J.5


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