메뉴 건너뛰기




Volumn 6, Issue 2, 2004, Pages 138-145

The DNA damage checkpoint and PKA pathways converge on APC substrates and Cdc20 to regulate mitotic progression

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; CELL CYCLE PROTEIN 20; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLINE; DNA; PROTEIN SUBUNIT; ANAPHASE PROMOTING COMPLEX; ANAPHASE-PROMOTING COMPLEX; CDC20 PROTEIN, S CEREVISIAE; CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; PROTEIN KINASE; SACCHAROMYCES CEREVISIAE PROTEIN; UBIQUITIN PROTEIN LIGASE;

EID: 1642602693     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1092     Document Type: Article
Times cited : (80)

References (35)
  • 1
    • 0030448251 scopus 로고    scopus 로고
    • Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
    • Cohen-Fix, O., Peters, J. M., Kirschner, M. W. & Koshland, D. Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes Dev. 10, 3081-3093 (1996).
    • (1996) Genes Dev. , vol.10 , pp. 3081-3093
    • Cohen-Fix, O.1    Peters, J.M.2    Kirschner, M.W.3    Koshland, D.4
  • 2
    • 0036284778 scopus 로고    scopus 로고
    • The anaphase-promoting complex: Proteolysis in mitosis and beyond
    • Peters, J. M. The anaphase-promoting complex: Proteolysis in mitosis and beyond. Mol. Cell 9, 931-943 (2002).
    • (2002) Mol. Cell , vol.9 , pp. 931-943
    • Peters, J.M.1
  • 3
    • 0029033504 scopus 로고
    • Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast
    • Irniger, S., Piatti, S., Michaelis, C. & Nasmyth, K. Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 81, 269-278 (1995).
    • (1995) Cell , vol.81 , pp. 269-278
    • Irniger, S.1    Piatti, S.2    Michaelis, C.3    Nasmyth, K.4
  • 4
    • 0001598759 scopus 로고    scopus 로고
    • Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast
    • Lim, H. H., Goh, P. Y. & Surana, U. Cdc20 is essential for the cyclosome-mediated proteolysis of both Pds1 and Clb2 during M phase in budding yeast. Curr. Biol. 8, 231-234 (1998).
    • (1998) Curr. Biol. , vol.8 , pp. 231-234
    • Lim, H.H.1    Goh, P.Y.2    Surana, U.3
  • 5
    • 0036682094 scopus 로고    scopus 로고
    • APC-depenclent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit
    • Wasch, R. & Cross, F. R. APC-depenclent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit. Nature 418, 556-562 (2002).
    • (2002) Nature , vol.418 , pp. 556-562
    • Wasch, R.1    Cross, F.R.2
  • 6
    • 0033527787 scopus 로고    scopus 로고
    • Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms
    • Sanchez, Y. et al. Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms. Science 286, 1166-1171 (1999).
    • (1999) Science , vol.286 , pp. 1166-1171
    • Sanchez, Y.1
  • 7
    • 0033151840 scopus 로고    scopus 로고
    • RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast
    • Gardner, R., Putnam, C. W. & Weinert, T. RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast. EMBO J. 18, 3173-3185 (1999).
    • (1999) EMBO J. , vol.18 , pp. 3173-3185
    • Gardner, R.1    Putnam, C.W.2    Weinert, T.3
  • 8
    • 0034597552 scopus 로고    scopus 로고
    • The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit
    • Wang, Y., Hu, F. & Elledge, S. J. The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit. Curr. Biol. 10, 1379-1382 (2000).
    • (2000) Curr. Biol. , vol.10 , pp. 1379-1382
    • Wang, Y.1    Hu, F.2    Elledge, S.J.3
  • 9
    • 0035977126 scopus 로고    scopus 로고
    • Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints
    • Hu, F. et al. Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. Cell 107, 655-665 (2001).
    • (2001) Cell , vol.107 , pp. 655-665
    • Hu, F.1
  • 10
    • 0034991258 scopus 로고    scopus 로고
    • Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function
    • Wang, H., Liu, D., Wang, Y., Qin, J. & Elledge, S. J. Pds1 phosphorylation in response to DNA damage is essential for its DNA damage checkpoint function. Genes Dev 15, 1361-1372 (2001).
    • (2001) Genes Dev. , vol.15 , pp. 1361-1372
    • Wang, H.1    Liu, D.2    Wang, Y.3    Qin, J.4    Elledge, S.J.5
  • 11
    • 0033180066 scopus 로고    scopus 로고
    • Pds1p of budding yeast has dual roles: Inhibition of anaphase initiation and regulation of mitotic exit
    • Cohen-Fix, O. & Koshland, D. Pds1p of budding yeast has dual roles: Inhibition of anaphase initiation and regulation of mitotic exit. Genes Dev. 13, 1950-1959 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 1950-1959
    • Cohen-Fix, O.1    Koshland, D.2
  • 12
    • 0033179736 scopus 로고    scopus 로고
    • Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and after DNA damage
    • Tinker-Kulberg, R. L. & Morgan, D. O. Pds1 and Esp1 control both anaphase and mitotic exit in normal cells and after DNA damage. Genes Dev. 13, 1936-1949 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 1936-1949
    • Tinker-Kulberg, R.L.1    Morgan, D.O.2
  • 13
    • 0034041786 scopus 로고    scopus 로고
    • Cyclic AMP regulates cell size of Schizosaccharomyces pombe through Cdc25 mitotic inducer
    • Kishimoto, N. & Yamashita, I. Cyclic AMP regulates cell size of Schizosaccharomyces pombe through Cdc25 mitotic inducer. Yeast 16, 523-529 (2000).
    • (2000) Yeast , vol.16 , pp. 523-529
    • Kishimoto, N.1    Yamashita, I.2
  • 14
    • 0033178811 scopus 로고    scopus 로고
    • Chromosome separation and exit from mitosis in budding yeast: Dependence on growth revealed by cAMP-mediated inhibition
    • Anghileri, P. et al. Chromosome separation and exit from mitosis in budding yeast: Dependence on growth revealed by cAMP-mediated inhibition. Exp. Cell Res. 250, 510-523 (1999).
    • (1999) Exp. Cell Res. , vol.250 , pp. 510-523
    • Anghileri, P.1
  • 15
    • 0030857274 scopus 로고    scopus 로고
    • Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast
    • Yamada, H., Kumada, K. & Yanagida, M. Distinct subunit functions and cell cycle regulated phosphorylation of 20S APC/cyclosome required for anaphase in fission yeast. J. Cell Sci. 110, 1793-1804 (1997).
    • (1997) J. Cell Sci. , vol.110 , pp. 1793-1804
    • Yamada, H.1    Kumada, K.2    Yanagida, M.3
  • 16
    • 0033386028 scopus 로고    scopus 로고
    • The budding yeast cohesin gene SCC1/MCD1/RHC21 genetically interacts with PKA, CDK and APC
    • Heo, S. J., Tatebayashi, K. & Ikeda, H. The budding yeast cohesin gene SCC1/MCD1/RHC21 genetically interacts with PKA, CDK and APC. Curr. Genet. 36, 329-338 (1999).
    • (1999) Curr. Genet. , vol.36 , pp. 329-338
    • Heo, S.J.1    Tatebayashi, K.2    Ikeda, H.3
  • 17
    • 0029857172 scopus 로고    scopus 로고
    • 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway
    • Yamashita, Y. M. et al. 20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathway. Nature 384, 276-279 (1996).
    • (1996) Nature , vol.384 , pp. 276-279
    • Yamashita, Y.M.1
  • 18
    • 0031991880 scopus 로고    scopus 로고
    • PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression
    • Kotani, S. et al. PKA and MPF-activated polo-like kinase regulate anaphase-promoting complex activity and mitosis progression. Mol. Cell 1, 371-380 (1998).
    • (1998) Mol. Cell , vol.1 , pp. 371-380
    • Kotani, S.1
  • 19
    • 0023394967 scopus 로고
    • Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase
    • Cannon, J. F. & Tatchell, K. Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase. Mol. Cell. Biol. 7, 2653-2663 (1987).
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 2653-2663
    • Cannon, J.F.1    Tatchell, K.2
  • 20
    • 0023130013 scopus 로고
    • Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae
    • Toda, T. et al. Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol. Cell. Biol. 7, 1371-1377 (1987).
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 1371-1377
    • Toda, T.1
  • 21
    • 0023658335 scopus 로고
    • Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase
    • Toda, T., Cameron, S., Sass, P., Zoller, M. & Wigler, M. Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50, 277-287 (1987).
    • (1987) Cell , vol.50 , pp. 277-287
    • Toda, T.1    Cameron, S.2    Sass, P.3    Zoller, M.4    Wigler, M.5
  • 22
    • 0027212282 scopus 로고
    • Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
    • Weinert, T. A. & Hartwell, L. H. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint. Genetics 134, 63-80 (1993).
    • (1993) Genetics , vol.134 , pp. 63-80
    • Weinert, T.A.1    Hartwell, L.H.2
  • 23
    • 0033969432 scopus 로고    scopus 로고
    • Cdc20 protein contains a destruction-box but, unlike Clb2, its proteolysis is not acutely dependent on the activity of anaphase-promoting complex
    • Goh, P. Y., Lim, H. H. & Surana, U. Cdc20 protein contains a destruction-box but, unlike Clb2, its proteolysis is not acutely dependent on the activity of anaphase-promoting complex. Eur. J. Biochem. 267, 434-449 (2000).
    • (2000) Eur. J. Biochem. , vol.267 , pp. 434-449
    • Goh, P.Y.1    Lim, H.H.2    Surana, U.3
  • 24
    • 0032543552 scopus 로고    scopus 로고
    • The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis
    • Prinz, S., Hwang, E. S., Visintin, R. & Amon, A. The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis. Curr. Biol. 8, 750-760 (1998).
    • (1998) Curr. Biol. , vol.8 , pp. 750-760
    • Prinz, S.1    Hwang, E.S.2    Visintin, R.3    Amon, A.4
  • 25
    • 0032512748 scopus 로고    scopus 로고
    • Budding yeast Cdc20: A target of the spindle checkpoint
    • Hwang, L. H. et al. Budding yeast Cdc20: A target of the spindle checkpoint. Science 279, 1041-1044 (1998).
    • (1998) Science , vol.279 , pp. 1041-1044
    • Hwang, L.H.1
  • 26
  • 27
    • 0037013243 scopus 로고    scopus 로고
    • Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach
    • O'Neill, T. et al. Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach. J. Biol. Chem. 277, 16102-16115 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 16102-16115
    • O'Neill, T.1
  • 28
    • 0036261612 scopus 로고    scopus 로고
    • Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation
    • Pan, X. & Heitman, J. Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. Mol. Cell. Biol. 22, 3981-393 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3981-4393
    • Pan, X.1    Heitman, J.2
  • 29
    • 0035007678 scopus 로고    scopus 로고
    • Evaluation of in vivo activation of protein kinase A under non-dissociable conditions through the overexpression of wild-type and mutant regulatory subunits in Saccharomyces cerevisiae
    • Portela, P., Zaremberg, V. & Moreno, S. Evaluation of in vivo activation of protein kinase A under non-dissociable conditions through the overexpression of wild-type and mutant regulatory subunits in Saccharomyces cerevisiae. Microbiology 147, 1149-1159 (2001).
    • (2001) Microbiology , vol.147 , pp. 1149-1159
    • Portela, P.1    Zaremberg, V.2    Moreno, S.3
  • 30
    • 0032526715 scopus 로고    scopus 로고
    • Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae
    • Colombo, S. et al. Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae. EMBO J. 17, 3326-3341 (1998).
    • (1998) EMBO J. , vol.17 , pp. 3326-3341
    • Colombo, S.1
  • 31
    • 0342803745 scopus 로고    scopus 로고
    • Glucose and ras activity influence the ubiquitin ligases APC/C and SCF in Saccharomyces cerevisiae
    • Irniger, S., Baumer, M. & Braus, G. H. Glucose and ras activity influence the ubiquitin ligases APC/C and SCF in Saccharomyces cerevisiae. Genetics 154, 1509-1521 (2000).
    • (2000) Genetics , vol.154 , pp. 1509-1521
    • Irniger, S.1    Baumer, M.2    Braus, G.H.3
  • 32
    • 0024849657 scopus 로고
    • The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae
    • Palmer, R. E., Koval, M. & Koshland, D. The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae. J. Cell Biol. 109, 3355-3366 (1989).
    • (1989) J. Cell Biol. , vol.109 , pp. 3355-3366
    • Palmer, R.E.1    Koval, M.2    Koshland, D.3
  • 33
    • 0038192061 scopus 로고    scopus 로고
    • Synergistic inhibition of APC/C by glucose and activated Ras proteins can be mediated by each of the Tpk1-3 proteins in Saccharomyces cerevisiae
    • Bolte, M., Dieckhoff, P., Krause, C., Braus, G. H. & Irniger, S. Synergistic inhibition of APC/C by glucose and activated Ras proteins can be mediated by each of the Tpk1-3 proteins in Saccharomyces cerevisiae. Microbiology 149, 1205-1216 (2003).
    • (2003) Microbiology , vol.149 , pp. 1205-1216
    • Bolte, M.1    Dieckhoff, P.2    Krause, C.3    Braus, G.H.4    Irniger, S.5
  • 34
    • 0028032104 scopus 로고
    • The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication
    • Foiani, M., Marini, F., Gamba, D., Lucchini, G. & Plevani, P. The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication. Mol. Cell. Biol. 14, 923-933 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 923-933
    • Foiani, M.1    Marini, F.2    Gamba, D.3    Lucchini, G.4    Plevani, P.5
  • 35
    • 0033653838 scopus 로고    scopus 로고
    • Signal transduction cascades regulating pseudohyphal differentiation of Saccharomyces cerevisiae
    • Pan, X., Harashima, T. & Heitman, J. Signal transduction cascades regulating pseudohyphal differentiation of Saccharomyces cerevisiae. Curr. Opin. Microbiol. 3, 567-572 (2000).
    • (2000) Curr. Opin. Microbiol. , vol.3 , pp. 567-572
    • Pan, X.1    Harashima, T.2    Heitman, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.