메뉴 건너뛰기




Volumn 8, Issue 11, 2016, Pages

Novel approaches to investigate one-carbon metabolism and related B-vitamins in blood pressure

Author keywords

ABPM; Blood pressure; DNA methylation; Hypertension; Methylenetetrahydrofolate reductase (MTHFR); Riboflavin

Indexed keywords

ACETYLSALICYLIC ACID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLAVINE ADENINE NUCLEOTIDE; HOMOCYSTEINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RIBOFLAVIN; VITAMIN B GROUP; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MTHFR PROTEIN, HUMAN; VITAMIN B COMPLEX;

EID: 84995543055     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu8110720     Document Type: Review
Times cited : (13)

References (143)
  • 1
    • 84995582802 scopus 로고    scopus 로고
    • accessed on 19 September
    • World Health Organisation—Global Health Observatory (GHO) Data for Raised Blood Pressure. Available online: http://www.who.int/gho/ncd/risk_factors/blood_pressure_prevalence:text/en/ (accessed on 19 September 2016).
    • (2016) Data for Raised Blood Pressure
  • 2
    • 84885353802 scopus 로고    scopus 로고
    • Hypertension prevalence, awareness, treatment and control in national surveys from England, the USA and Canada, and correlation with stroke and ischaemic heart disease mortality: A cross-sectional study
    • [CrossRef] [PubMed]
    • Joffres, M., Falaschetti, E., Gillespie, C., Robitaille, C., Loustalot, F., Poulter, N., McAlister, F.A., Johansen, H., Baclic, O., Campbell, N. Hypertension prevalence, awareness, treatment and control in national surveys from England, the USA and Canada, and correlation with stroke and ischaemic heart disease mortality: A cross-sectional study. BMJ Open 2013, 3, e003423. [CrossRef] [PubMed]
    • (2013) BMJ Open , vol.3
    • Joffres, M.1    Falaschetti, E.2    Gillespie, C.3    Robitaille, C.4    Loustalot, F.5    Poulter, N.6    McAlister, F.A.7    Johansen, H.8    Baclic, O.9    Campbell, N.10
  • 3
    • 12344282783 scopus 로고    scopus 로고
    • Global burden of hypertension: Analysis of worldwide data
    • [CrossRef]
    • Kearney, P.M., Whelton, M., Reynolds, K., Muntner, P., Whelton, P.K., He, J. Global burden of hypertension: Analysis of worldwide data. Lancet 2005, 365, 217-223. [CrossRef]
    • (2005) Lancet , vol.365 , pp. 217-223
    • Kearney, P.M.1    Whelton, M.2    Reynolds, K.3    Muntner, P.4    Whelton, P.K.5    He, J.6
  • 5
    • 84960094179 scopus 로고    scopus 로고
    • Rahimi, K. Blood pressure lowering for prevention of cardiovascular disease and death: A systematic review and meta-analysis
    • [CrossRef]
    • Ettehad, D., Emdin, C.A., Kiran, A., Anderson, S.G., Callender, T., Emberson, J., Chalmers, J., Rodgers, A., Rahimi, K. Blood pressure lowering for prevention of cardiovascular disease and death: A systematic review and meta-analysis. Lancet 2016, 387, 957-967. [CrossRef]
    • (2016) Lancet , vol.387 , pp. 957-967
    • Ettehad, D.1    Emdin, C.A.2    Kiran, A.3    Erson, S.G.4    Callender, T.5    Emberson, J.6    Chalmers, J.7    Rodgers, A.8
  • 6
    • 0037079309 scopus 로고    scopus 로고
    • Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies
    • [CrossRef]
    • Lewington, S., Clarke, R., Qizilbash, N., Peto, R., Collins, R. Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002, 360, 1903-1913. [CrossRef]
    • (2002) Lancet , vol.360 , pp. 1903-1913
    • Lewington, S.1    Clarke, R.2    Qizilbash, N.3    Peto, R.4    Collins, R.5
  • 7
    • 84962493906 scopus 로고    scopus 로고
    • Royal College of Physicians: London, UK
    • National Collaborating Centre for Chronic Conditions and the British Hypertension Society. Hypertension in Adults: Diagnosis and Management Management, Royal College of Physicians: London, UK, 2011.
    • (2011) Hypertension in Adults: Diagnosis and Management Management
  • 9
    • 84959363424 scopus 로고    scopus 로고
    • Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: Updated systematic review and meta-analysis
    • [CrossRef]
    • Xie, X., Atkins, E., Lv, J., Bennett, A., Neal, B., Ninomiya, T., Woodward, M., MacMahon, S., Turnbull, F., Hillis, G.S., et al. Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: Updated systematic review and meta-analysis. Lancet 2016, 387, 435-443. [CrossRef]
    • (2016) Lancet , vol.387 , pp. 435-443
    • Xie, X.1    Atkins, E.2    Lv, J.3    Bennett, A.4    Neal, B.5    Ninomiya, T.6    Woodward, M.7    Macmahon, S.8    Turnbull, F.9    Hillis, G.S.10
  • 15
    • 36348950227 scopus 로고    scopus 로고
    • A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension
    • [CrossRef] [PubMed]
    • Qian, X., Lu, Z., Tan, M., Liu, H., Lu, D. A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension. Eur. J. Hum. Genet. 2007, 15, 1239-1245. [CrossRef] [PubMed]
    • (2007) Eur. J. Hum. Genet , vol.15 , pp. 1239-1245
    • Qian, X.1    Lu, Z.2    Tan, M.3    Liu, H.4    Lu, D.5
  • 16
    • 84858709356 scopus 로고    scopus 로고
    • Strong association of methylenetetrahydrofolate reductase gene C677T polymorphism with hypertension and hypertension-in-pregnancy in Chinese: A meta-analysis
    • [CrossRef] [PubMed]
    • Niu, W.-Q., You, Y.-G., Qi, Y. Strong association of methylenetetrahydrofolate reductase gene C677T polymorphism with hypertension and hypertension-in-pregnancy in Chinese: A meta-analysis. J. Hum. Hypertens. 2012, 26, 259-267. [CrossRef] [PubMed]
    • (2012) J. Hum. Hypertens. , vol.26 , pp. 259-267
    • Niu, W.-Q.1    You, Y.-G.2    Qi, Y.3
  • 17
    • 84922211351 scopus 로고    scopus 로고
    • Association between methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and essential hypertension: A systematic review and meta-analysis
    • [CrossRef] [PubMed]
    • Wu, Y.L., Hu, C.Y., Lu, S.S., Gong, F.F., Feng, F., Qian, Z.Z., Ding, X.X., Yang, H.Y., Sun, Y.H. Association between methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and essential hypertension: A systematic review and meta-analysis. Metabolism 2014, 63, 1503-1511. [CrossRef] [PubMed]
    • (2014) Metabolism , vol.63 , pp. 1503-1511
    • Wu, Y.L.1    Hu, C.Y.2    Lu, S.S.3    Gong, F.F.4    Feng, F.5    Qian, Z.Z.6    Ding, X.X.7    Yang, H.Y.8    Sun, Y.H.9
  • 18
    • 84895550128 scopus 로고    scopus 로고
    • Associations of MTHFR gene polymorphisms with hypertension and hypertension in pregnancy: A meta-analysis from 114 studies with 15411 cases and 21970 controls
    • [CrossRef] [PubMed]
    • Yang, B., Fan, S., Zhi, X., Li, Y., Liu, Y., Wang, D., He, M., Hou, Y., Zheng, Q., Sun, G. Associations of MTHFR gene polymorphisms with hypertension and hypertension in pregnancy: A meta-analysis from 114 studies with 15411 cases and 21970 controls. PLoS ONE 2014, 9, e87497. [CrossRef] [PubMed]
    • (2014) Plos ONE , vol.9
    • Yang, B.1    Fan, S.2    Zhi, X.3    Li, Y.4    Liu, Y.5    Wang, D.6    He, M.7    Hou, Y.8    Zheng, Q.9    Sun, G.10
  • 19
    • 84920274080 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase C677T gene polymorphism and essential hypertension: A meta-analysis of 10,415 subjects
    • [CrossRef] [PubMed]
    • Yang, K.-M., Jia, J., Mao, L.-N., Men, C., Tang, K.-T., Li, Y.-Y., Ding, H.-X., Zhan, Y.-Y. Methylenetetrahydrofolate reductase C677T gene polymorphism and essential hypertension: A meta-analysis of 10,415 subjects. Biomed. Rep. 2014, 2, 699-708. [CrossRef] [PubMed]
    • (2014) Biomed. Rep , vol.2 , pp. 699-708
    • Yang, K.-M.1    Jia, J.2    Mao, L.-N.3    Men, C.4    Tang, K.-T.5    Li, Y.-Y.6    Ding, H.-X.7    Zhan, Y.-Y.8
  • 20
    • 77149145514 scopus 로고    scopus 로고
    • Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C→T polymorphism in MTHFR
    • [CrossRef] [PubMed]
    • Horigan, G., McNulty, H., Ward, M., Strain, J.J., Purvis, J., Scott, J.M. Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C→T polymorphism in MTHFR. J. Hypertens. 2010, 28, 478-486. [CrossRef] [PubMed]
    • (2010) J. Hypertens , vol.28 , pp. 478-486
    • Horigan, G.1    McNulty, H.2    Ward, M.3    Strain, J.J.4    Purvis, J.5    Scott, J.M.6
  • 21
    • 84857863459 scopus 로고    scopus 로고
    • Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: A 4-y follow-up
    • [CrossRef] [PubMed]
    • Wilson, C.P., Ward, M., McNulty, H., Strain, J.J., Trouton, T.G., Horigan, G., Purvis, J., Scott, J.M. Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: A 4-y follow-up. Am. J. Clin. Nutr. 2012, 95, 766-772. [CrossRef] [PubMed]
    • (2012) Am. J. Clin. Nutr , vol.95 , pp. 766-772
    • Wilson, C.P.1    Ward, M.2    McNulty, H.3    Strain, J.J.4    Trouton, T.G.5    Horigan, G.6    Purvis, J.7    Scott, J.M.8
  • 22
    • 84878927079 scopus 로고    scopus 로고
    • Blood pressure in treated hypertensive individuals with the mthfr 677tt genotype is responsive to intervention with riboflavin: Findings of a targeted randomized trial
    • [CrossRef] [PubMed]
    • Wilson, C.P., McNulty, H., Ward, M., Strain, J.J., Trouton, T.G., Hoeft, B.A., Weber, P., Roos, F.F., Horigan, G., McAnena, L., et al. Blood pressure in treated hypertensive individuals with the mthfr 677tt genotype is responsive to intervention with riboflavin: Findings of a targeted randomized trial. Hypertension 2013, 61, 1302-1308. [CrossRef] [PubMed]
    • (2013) Hypertension , vol.61 , pp. 1302-1308
    • Wilson, C.P.1    McNulty, H.2    Ward, M.3    Strain, J.J.4    Trouton, T.G.5    Hoeft, B.A.6    Weber, P.7    Roos, F.F.8    Horigan, G.9    McAnena, L.10
  • 23
    • 84957109152 scopus 로고    scopus 로고
    • Riboflavin Lowers Blood Pressure: A Review of a Novel Gene-nutrient Interaction
    • Strain, J., Hughes, C.F., Mcnulty, H., Ward, M. Riboflavin Lowers Blood Pressure: A Review of a Novel Gene-nutrient Interaction. Nutr. Food Sci. Res. 2015, 2, 3-6.
    • (2015) Nutr. Food Sci. Res , vol.2 , pp. 3-6
    • Strain, J.1    Hughes, C.F.2    McNulty, H.3    Ward, M.4
  • 25
    • 0000516777 scopus 로고
    • Portable blood pressure recorder Accuracy and preliminary use in evaluating intradaily variations in pressure
    • [CrossRef]
    • Hinman, A.T., Engel, B.T., Bickford, A.F. Portable blood pressure recorder Accuracy and preliminary use in evaluating intradaily variations in pressure. Am. Heart J. 1962, 63, 663-668. [CrossRef]
    • (1962) Am. Heart J , vol.63 , pp. 663-668
    • Hinman, A.T.1    Engel, B.T.2    Bickford, A.F.3
  • 27
    • 0030962568 scopus 로고    scopus 로고
    • Unmetabolized folic acid in serum: Acute studies in subjects consuming fortified food and supplements
    • [PubMed]
    • Kelly, P., McPartlin, J., Goggins, M., Weir, D.G., Scott, J.M. Unmetabolized folic acid in serum: Acute studies in subjects consuming fortified food and supplements. Am. J. Clin. Nutr. 1997, 65, 1790-1795. [PubMed]
    • (1997) Am. J. Clin. Nutr , vol.65 , pp. 1790-1795
    • Kelly, P.1    McPartlin, J.2    Goggins, M.3    Weir, D.G.4    Scott, J.M.5
  • 28
    • 77953061018 scopus 로고    scopus 로고
    • Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors
    • [CrossRef] [PubMed]
    • Morris, M.S., Jacques, P.F., Rosenberg, I.H., Selhub, J. Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. Am. J. Clin. Nutr. 2010, 91, 1733-1744. [CrossRef] [PubMed]
    • (2010) Am. J. Clin. Nutr , vol.91 , pp. 1733-1744
    • Morris, M.S.1    Jacques, P.F.2    Rosenberg, I.H.3    Selhub, J.4
  • 31
    • 84938094683 scopus 로고    scopus 로고
    • B-vitamins and bone in health and disease: The current evidence
    • [CrossRef] [PubMed]
    • Clarke, M., Ward, M., Strain, J.J., Hoey, L., Dickey, W., McNulty, H. B-vitamins and bone in health and disease: The current evidence. Proc. Nutr. Soc. 2014, 73, 330-339. [CrossRef] [PubMed]
    • (2014) Proc. Nutr. Soc. , vol.73 , pp. 330-339
    • Clarke, M.1    Ward, M.2    Strain, J.J.3    Hoey, L.4    Dickey, W.5    McNulty, H.6
  • 32
    • 84860872362 scopus 로고    scopus 로고
    • C1 metabolism and CVD outcomes in older adults
    • [CrossRef] [PubMed]
    • McNulty, H., Strain, J.J., Pentieva, K., Ward, M. C1 metabolism and CVD outcomes in older adults. Proc. Nutr. Soc. 2012, 71, 213-221. [CrossRef] [PubMed]
    • (2012) Proc. Nutr. Soc , vol.71 , pp. 213-221
    • McNulty, H.1    Strain, J.J.2    Pentieva, K.3    Ward, M.4
  • 33
    • 27744603884 scopus 로고    scopus 로고
    • Dose-dependent effects of folic acid on blood concentrations of homocysteine: A meta-analysis of the randomized trials 1-3
    • Homocysteine Lowering Trialists. Dose-dependent effects of folic acid on blood concentrations of homocysteine: A meta-analysis of the randomized trials 1-3. Am. J. Clin. Nutr. 2005, 82, 806-812.
    • (2005) Am. J. Clin. Nutr , vol.82 , pp. 806-812
  • 34
    • 78651295457 scopus 로고    scopus 로고
    • A dose-finding trial of the effect of long-term folic acid intervention: Implications for food fortification policy
    • [CrossRef] [PubMed]
    • Tighe, P., Ward, M., Mcnulty, H., Finnegan, O., Dunne, A., Strain, J.J., Molloy, A.M., Duffy, M., Pentieva, K., et al. A dose-finding trial of the effect of long-term folic acid intervention: Implications for food fortification policy. Am. J. Clin. Nutr. 2011, 93, 11-18. [CrossRef] [PubMed]
    • (2011) Am. J. Clin. Nutr , vol.93 , pp. 11-18
    • Tighe, P.1    Ward, M.2    McNulty, H.3    Finnegan, O.4    Dunne, A.5    Strain, J.J.6    Molloy, A.M.7    Duffy, M.8    Pentieva, K.9
  • 35
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis
    • [CrossRef] [PubMed]
    • Wald, D.S., Law, M., Morris, J.K. Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis. BMJ 2002, 325, 1202. [CrossRef] [PubMed]
    • (2002) BMJ , vol.325 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 36
    • 0037164104 scopus 로고    scopus 로고
    • Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis
    • Homocysteine Studies Collaboration. Homocysteine and risk of ischemic heart disease and stroke: A meta-analysis. JAMA 2002, 288, 2015-2022.
    • (2002) JAMA , vol.288 , pp. 2015-2022
  • 37
    • 77949656345 scopus 로고    scopus 로고
    • The MTHFR C677T polymorphism, B-vitamins and blood pressure
    • [CrossRef] [PubMed]
    • Wilson, C.P., McNulty, H., Scott, J.M., Strain, J.J., Ward, M. The MTHFR C677T polymorphism, B-vitamins and blood pressure. Proc. Nutr. Soc. 2010, 69, 156-165. [CrossRef] [PubMed]
    • (2010) Proc. Nutr. Soc , vol.69 , pp. 156-165
    • Wilson, C.P.1    McNulty, H.2    Scott, J.M.3    Strain, J.J.4    Ward, M.5
  • 38
    • 33645753544 scopus 로고    scopus 로고
    • Homocysteine lowering with folic acid and B vitamins in vascular disease
    • The Heart Outcomes Prevention Evaluation Investigators (HOPE) 2 Investigators. Homocysteine lowering with folic acid and B vitamins in vascular disease. N. Engl. J. Med. 2006, 354, 1567-1577.
    • (2006) N. Engl. J. Med , vol.354 , pp. 1567-1577
  • 39
    • 34249730020 scopus 로고    scopus 로고
    • Efficacy of folic acid supplementation in stroke prevention: A meta-analysis
    • [CrossRef]
    • Wang, X., Qin, X., Demirtas, H., Li, J., Mao, G., Huo, Y., Sun, N., Liu, L., Xu, X. Efficacy of folic acid supplementation in stroke prevention: A meta-analysis. Lancet 2007, 369, 1876-1882. [CrossRef]
    • (2007) Lancet , vol.369 , pp. 1876-1882
    • Wang, X.1    Qin, X.2    Demirtas, H.3    Li, J.4    Mao, G.5    Huo, Y.6    Sun, N.7    Liu, L.8    Xu, X.9
  • 40
    • 77953133802 scopus 로고    scopus 로고
    • Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: A meta-analysis
    • [CrossRef] [PubMed]
    • Lee, M., Hong, K.-S., Chang, S.-C., Saver, J.L. Efficacy of homocysteine-lowering therapy with folic Acid in stroke prevention: A meta-analysis. Stroke 2010, 41, 1205-1212. [CrossRef] [PubMed]
    • (2010) Stroke , vol.41 , pp. 1205-1212
    • Lee, M.1    Hong, K.-S.2    Chang, S.-C.3    Saver, J.L.4
  • 41
    • 84861191434 scopus 로고    scopus 로고
    • Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: A post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial
    • [CrossRef]
    • Hankey, G.J., Eikelboom, J.W., Yi, Q., Lees, K.R., Chen, C., Xavier, D., Navarro, J.C., Ranawaka, U.K., Uddin, W., Ricci, S., et al. Antiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: A post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial. Lancet Neurol. 2012, 11, 512-520. [CrossRef]
    • (2012) Lancet Neurol , vol.11 , pp. 512-520
    • Hankey, G.J.1    Eikelboom, J.W.2    Yi, Q.3    Lees, K.R.4    Chen, C.5    Xavier, D.6    Navarro, J.C.7    Ranawaka, U.K.8    Uddin, W.9    Ricci, S.10
  • 42
    • 84992752981 scopus 로고    scopus 로고
    • Folic Acid Therapy Reduces the First Stroke Risk AssociatedWith Hypercholesterolemia Among Hypertensive Patients
    • [CrossRef] [PubMed]
    • Qin, X., Li, J., Spence, J.D., Zhang, Y., Li, Y., Wang, X., Wang, B., Sun, N., Chen, F., Guo, J., et al. Folic Acid Therapy Reduces the First Stroke Risk AssociatedWith Hypercholesterolemia Among Hypertensive Patients. Stroke 2016, 47, 2805-2812. [CrossRef] [PubMed]
    • (2016) Stroke , vol.47 , pp. 2805-2812
    • Qin, X.1    Li, J.2    Spence, J.D.3    Zhang, Y.4    Li, Y.5    Wang, X.6    Wang, B.7    Sun, N.8    Chen, F.9    Guo, J.10
  • 43
    • 1342309318 scopus 로고    scopus 로고
    • Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: The Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial
    • [CrossRef] [PubMed]
    • Toole, J.F., Malinow, M.R., Chambless, L.E., Spence, J.D., Pettigrew, L.C., Howard, V.J., Sides, E.G., Wang, C.-H., Stampfer, M. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: The Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 2004, 291, 565-575. [CrossRef] [PubMed]
    • (2004) JAMA , vol.291 , pp. 565-575
    • Toole, J.F.1    Malinow, M.R.2    Chambless, L.E.3    Spence, J.D.4    Pettigrew, L.C.5    Howard, V.J.6    Sides, E.G.7    Wang, C.-H.8    Stampfer, M.9
  • 45
    • 0035569991 scopus 로고    scopus 로고
    • Long-term homocysteinelowering treatment with folic acid plus pyridoxine is associated with decreased blood pressure but not with improved brachial artery endothelium-dependent vasodilation or carotid artery stiffness
    • [CrossRef] [PubMed]
    • Van Dijk, R.A.J.M., Rauwerda, J.A., Steyn, M., Twisk, J.W.R., Stehouwer, C.D.A. Long-term homocysteinelowering treatment with folic acid plus pyridoxine is associated with decreased blood pressure but not with improved brachial artery endothelium-dependent vasodilation or carotid artery stiffness. Arterioscler. Thromb. Vasc. Biol. 2001, 21, 2072-2079. [CrossRef] [PubMed]
    • (2001) Arterioscler. Thromb. Vasc. Biol , vol.21 , pp. 2072-2079
    • Van Dijk, R.A.J.M.1    Rauwerda, J.A.2    Steyn, M.3    Twisk, J.W.R.4    Stehouwer, C.D.A.5
  • 46
    • 0036911080 scopus 로고    scopus 로고
    • Folic acid enhances endothelial function and reduces blood pressure in smokers: A randomized controlled trial
    • [CrossRef] [PubMed]
    • Mangoni, A.A., Sherwood, R.A., Swift, C.G., Jackson, S.H.D. Folic acid enhances endothelial function and reduces blood pressure in smokers: A randomized controlled trial. J. Intern. Med. 2002, 252, 497-503. [CrossRef] [PubMed]
    • (2002) J. Intern. Med , vol.252 , pp. 497-503
    • Mangoni, A.A.1    Sherwood, R.A.2    Swift, C.G.3    Jackson, S.H.D.4
  • 47
    • 0042769170 scopus 로고    scopus 로고
    • Relationship of systolic blood pressure with plasma homocysteine: Importance of smoking status
    • [CrossRef] [PubMed]
    • Kennedy, B.P., Farag, N.H., Ziegler, A.G., Mills, P.J. Relationship of systolic blood pressure with plasma homocysteine: Importance of smoking status. J. Hypertens. 2003, 21, 1307-1312. [CrossRef] [PubMed]
    • (2003) J. Hypertens , vol.21 , pp. 1307-1312
    • Kennedy, B.P.1    Farag, N.H.2    Ziegler, A.G.3    Mills, P.J.4
  • 48
    • 0037163849 scopus 로고    scopus 로고
    • MTHFR Studies Collaboration Group. MTHFR 677C→T polymorphism and risk of coronary heart disease: A meta-analysis
    • [CrossRef] [PubMed]
    • Klerk, M., Verhoef, P., Clarke, R., Blom, H.J., Kok, F.J., Schouten, E.G., MTHFR Studies Collaboration Group. MTHFR 677C→T polymorphism and risk of coronary heart disease: A meta-analysis. JAMA 2002, 288, 2023-2031. [CrossRef] [PubMed]
    • (2002) JAMA , vol.288 , pp. 2023-2031
    • Klerk, M.1    Verhoef, P.2    Clarke, R.3    Blom, H.J.4    Kok, F.J.5    Schouten, E.G.6
  • 49
    • 12344309062 scopus 로고    scopus 로고
    • Homocysteine and stroke: Evidence on a causal link from mendelian randomisation
    • [CrossRef]
    • Casas, J.P., Bautista, L.E., Smeeth, L., Sharma, P., Hingorani, A.D. Homocysteine and stroke: Evidence on a causal link from mendelian randomisation. Lancet 2005, 365, 224-232. [CrossRef]
    • (2005) Lancet , vol.365 , pp. 224-232
    • Casas, J.P.1    Bautista, L.E.2    Smeeth, L.3    Sharma, P.4    Hingorani, A.D.5
  • 50
    • 27744471516 scopus 로고    scopus 로고
    • Meta-analysis of MTHFR 677C→T polymorphism and coronary heart disease: Does totality of evidence support causal role for homocysteine and preventive potential of folate?
    • [CrossRef] [PubMed]
    • Lewis, S.J., Ebrahim, S., Davey Smith, G. Meta-analysis of MTHFR 677C→T polymorphism and coronary heart disease: Does totality of evidence support causal role for homocysteine and preventive potential of folate? BMJ 2005, 331, 1053. [CrossRef] [PubMed]
    • (2005) BMJ , vol.331 , pp. 1053
    • Lewis, S.J.1    Ebrahim, S.2    Davey Smith, G.3
  • 51
    • 80051695692 scopus 로고    scopus 로고
    • Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: A meta-analysis of genetic studies and randomised trials
    • [CrossRef]
    • Holmes, M.V., Newcombe, P., Hubacek, J.A., Sofat, R., Ricketts, S.L., Cooper, J., Breteler, M.M.B., Bautista, L.E., Sharma, P., Whittaker, J.C. Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: A meta-analysis of genetic studies and randomised trials. Lancet 2011, 378, 584-594. [CrossRef]
    • (2011) Lancet , vol.378 , pp. 584-594
    • Holmes, M.V.1    Newcombe, P.2    Hubacek, J.A.3    Sofat, R.4    Ricketts, S.L.5    Cooper, J.6    Breteler, M.M.B.7    Bautista, L.E.8    Sharma, P.9    Whittaker, J.C.10
  • 52
    • 84857711683 scopus 로고    scopus 로고
    • MTHFR Studies Collaborative Group Homocysteine and coronary heart disease: Meta-analysis of MTHFR case-control studies, avoiding publication bias
    • [CrossRef] [PubMed]
    • Clarke, R., Bennett, D.A., Parish, S., Verhoef, P., Dötsch-Klerk, M., Lathrop, M., Xu, P., Nordestgaard, B.G., Holm, H., Hopewell, J.C., et al. MTHFR Studies Collaborative Group Homocysteine and coronary heart disease: Meta-analysis of MTHFR case-control studies, avoiding publication bias. PLoS Med. 2012, 9, e1001177. [CrossRef] [PubMed]
    • (2012) Plos Med , vol.9
    • Clarke, R.1    Bennett, D.A.2    Parish, S.3    Verhoef, P.4    Dötsch-Klerk, M.5    Lathrop, M.6    Xu, P.7    Nordestgaard, B.G.8    Holm, H.9    Hopewell, J.C.10
  • 55
    • 0041326346 scopus 로고    scopus 로고
    • Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): Findings from over 7000 newborns from 16 areas world wide
    • [CrossRef] [PubMed]
    • Wilcken, B., Bamforth, F., Li, Z., Zhu, H., Ritvanen, A., Renlund, M., Stoll, C., Alembik, Y., Dott, B., Czeizel, A.E., et al. Geographical and ethnic variation of the 677C>T allele of 5,10 methylenetetrahydrofolate reductase (MTHFR): Findings from over 7000 newborns from 16 areas world wide. J. Med. Genet. 2003, 40, 619-625. [CrossRef] [PubMed]
    • (2003) J. Med. Genet , vol.40 , pp. 619-625
    • Wilcken, B.1    Bamforth, F.2    Li, Z.3    Zhu, H.4    Ritvanen, A.5    Renlund, M.6    Stoll, C.7    Alembik, Y.8    Dott, B.9    Czeizel, A.E.10
  • 56
    • 84966642548 scopus 로고    scopus 로고
    • Riboflavin status, MTHFR genotype and blood pressure: Current evidence and implications for personalised nutrition
    • [CrossRef] [PubMed]
    • McAuley, E., McNulty, H., Hughes, C., Strain, J.J., Ward, M. Riboflavin status, MTHFR genotype and blood pressure: Current evidence and implications for personalised nutrition. Proc. Nutr. Soc. 2016, 75, 405-414. [CrossRef] [PubMed]
    • (2016) Proc. Nutr. Soc , vol.75 , pp. 405-414
    • McAuley, E.1    McNulty, H.2    Hughes, C.3    Strain, J.J.4    Ward, M.5
  • 57
    • 0032895522 scopus 로고    scopus 로고
    • The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia
    • [PubMed]
    • Guenther, B.D., Sheppard, C.A., Tran, P., Rozen, R., Matthews, R.G., Ludwig, M.L. The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia. Nat. Struct. Biol. 1999, 6, 359-365. [PubMed]
    • (1999) Nat. Struct. Biol , vol.6 , pp. 359-365
    • Guenther, B.D.1    Sheppard, C.A.2    Tran, P.3    Rozen, R.4    Matthews, R.G.5    Ludwig, M.L.6
  • 58
    • 0035909980 scopus 로고    scopus 로고
    • Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase
    • [CrossRef] [PubMed]
    • Yamada, K., Chen, Z., Rozen, R., Matthews, R.G. Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase. Proc. Natl. Acad. Sci. USA 2001, 98, 14853-14858. [CrossRef] [PubMed]
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 14853-14858
    • Yamada, K.1    Chen, Z.2    Rozen, R.3    Matthews, R.G.4
  • 59
    • 0032573077 scopus 로고    scopus 로고
    • Common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
    • [CrossRef] [PubMed]
    • Bagley, P.J., Selhub, J. A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. Proc. Natl. Acad. Sci. USA 1998, 95, 13217-13220. [CrossRef] [PubMed]
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13217-13220
    • Bagley, P.J.1    Selhub, J.A.2
  • 60
    • 84901357111 scopus 로고    scopus 로고
    • A structured-based model for the decreased activity of Ala222Val and Glu429Ala methylenetetrahydrofolate reductase (MTHFR) mutants
    • [CrossRef] [PubMed]
    • Shahzad, K., Hai, A., Ahmed, A., Kizilbash, N., Alruwaili, J. A structured-based model for the decreased activity of Ala222Val and Glu429Ala methylenetetrahydrofolate reductase (MTHFR) mutants. Bioinformation 2013, 9, 929-936. [CrossRef] [PubMed]
    • (2013) Bioinformation , vol.9 , pp. 929-936
    • Shahzad, K.1    Hai, A.2    Ahmed, A.3    Kizilbash, N.4    Alruwaili, J.5
  • 61
    • 33748645122 scopus 로고    scopus 로고
    • 5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: Effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling
    • [CrossRef] [PubMed]
    • Antoniades, C., Shirodaria, C., Warrick, N., Cai, S., De Bono, J., Lee, J., Leeson, P., Neubauer, S., Ratnatunga, C., Pillai, R., et al. 5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: Effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling. Circulation 2006, 114, 1193-1201. [CrossRef] [PubMed]
    • (2006) Circulation , vol.114 , pp. 1193-1201
    • Antoniades, C.1    Shirodaria, C.2    Warrick, N.3    Cai, S.4    De Bono, J.5    Lee, J.6    Leeson, P.7    Neubauer, S.8    Ratnatunga, C.9    Pillai, R.10
  • 62
    • 66549090409 scopus 로고    scopus 로고
    • MTHFR 677C>T polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis
    • [CrossRef] [PubMed]
    • Antoniades, C., Shirodaria, C., Leeson, P., Baarholm, O.A., Van-Assche, T., Cunnington, C., Pillai, R., Ratnatunga, C., Tousoulis, D., Stefanadis, C., et al. MTHFR 677C>T polymorphism reveals functional importance for 5-methyltetrahydrofolate, not homocysteine, in regulation of vascular redox state and endothelial function in human atherosclerosis. Circulation 2009, 119, 2507-2515. [CrossRef] [PubMed]
    • (2009) Circulation , vol.119 , pp. 2507-2515
    • Antoniades, C.1    Shirodaria, C.2    Leeson, P.3    Baarholm, O.A.4    Van-Assche, T.5    Cunnington, C.6    Pillai, R.7    Ratnatunga, C.8    Tousoulis, D.9    Stefanadis, C.10
  • 63
    • 84862248102 scopus 로고    scopus 로고
    • Folate and DNA methylation: A review of molecular mechanisms and the evidence for folate’s role
    • [CrossRef] [PubMed]
    • Crider, K.S., Yang, T.P., Berry, R.J., Bailey, L.B. Folate and DNA methylation: A review of molecular mechanisms and the evidence for folate’s role. Adv. Nutr. 2012, 3, 21-38. [CrossRef] [PubMed]
    • (2012) Adv. Nutr , vol.3 , pp. 21-38
    • Crider, K.S.1    Yang, T.P.2    Berry, R.J.3    Bailey, L.B.4
  • 64
    • 84871943160 scopus 로고    scopus 로고
    • Folate in pregnancy and imprinted gene and repeat element methylation in the offspring
    • [CrossRef] [PubMed]
    • Haggarty, P., Hoad, G., Campbell, D.M., Horgan, G.W., Piyathilake, C., McNeill, G. Folate in pregnancy and imprinted gene and repeat element methylation in the offspring. Am. J. Clin. Nutr. 2013, 97, 94-99. [CrossRef] [PubMed]
    • (2013) Am. J. Clin. Nutr , vol.97 , pp. 94-99
    • Haggarty, P.1    Hoad, G.2    Campbell, D.M.3    Horgan, G.W.4    Piyathilake, C.5    McNeill, G.6
  • 67
    • 84969988447 scopus 로고    scopus 로고
    • Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis. Birth Defects Res
    • [CrossRef] [PubMed]
    • Wang, L., Shangguan, S., Chang, S., Yu, X., Wang, Z., Lu, X., Wu, L., Zhang, T. Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis. Birth Defects Res. A Clin. Mol. Teratol. 2016, 106, 667-674. [CrossRef] [PubMed]
    • (2016) A Clin. Mol. Teratol , vol.106 , pp. 667-674
    • Wang, L.1    Shangguan, S.2    Chang, S.3    Yu, X.4    Wang, Z.5    Lu, X.6    Wu, L.7    Zhang, T.8
  • 68
    • 84957548931 scopus 로고    scopus 로고
    • Effect of MTHFR gene polymorphism impact on atherosclerosis via genome-wide methylation
    • [CrossRef] [PubMed]
    • Lin, X., Lu, Q., Wang, T. Effect of MTHFR gene polymorphism impact on atherosclerosis via genome-wide methylation. Med. Sci. Monit. 2016, 22, 341-345. [CrossRef] [PubMed]
    • (2016) Med. Sci. Monit , vol.22 , pp. 341-345
    • Lin, X.1    Lu, Q.2    Wang, T.3
  • 69
    • 84937542647 scopus 로고    scopus 로고
    • Correlation between MTHFR gene methylation and pre-eclampsia, and its clinical significance
    • [CrossRef] [PubMed]
    • Ge, J., Wang, J., Zhang, F., Diao, B., Song, Z.F., Shan, L.L., Wang, W., Cao, H.J., Li, X.Q. Correlation between MTHFR gene methylation and pre-eclampsia, and its clinical significance. Genet. Mol. Res. 2015, 14, 8021-8028. [CrossRef] [PubMed]
    • (2015) Genet. Mol. Res , vol.14 , pp. 8021-8028
    • Ge, J.1    Wang, J.2    Zhang, F.3    Diao, B.4    Song, Z.F.5    Shan, L.L.6    Wang, W.7    Cao, H.J.8    Li, X.Q.9
  • 71
    • 84939630063 scopus 로고    scopus 로고
    • Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: The role of B vitamins supplementation
    • [CrossRef] [PubMed]
    • Pusceddu, I., Herrmann, M., Kirsch, S.H., Werner, C., Hübner, U., Bodis, M., Laufs, U., Wagenpfeil, S., Geisel, J., Herrmann, W. Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: The role of B vitamins supplementation. Eur. J. Nutr. 2016, 55, 1863-1873. [CrossRef] [PubMed]
    • (2016) Eur. J. Nutr , vol.55 , pp. 1863-1873
    • Pusceddu, I.1    Herrmann, M.2    Kirsch, S.H.3    Werner, C.4    Hübner, U.5    Bodis, M.6    Laufs, U.7    Wagenpfeil, S.8    Geisel, J.9    Herrmann, W.10
  • 73
    • 84875429631 scopus 로고    scopus 로고
    • 2013 Ambulatory blood pressure monitoring recommendations for the diagnosis of adult hypertension, assessment of cardiovascular and other hypertension-associated risk, and attainment of therapeutic goals
    • [CrossRef] [PubMed]
    • Hermida, R.C., Smolensky, M.H., Ayala, D.E., Portaluppi, F., Crespo, J.J., Fabbian, F., Haus, E., Manfredini, R., Mojón, A., Moyá, A., et al. 2013 Ambulatory blood pressure monitoring recommendations for the diagnosis of adult hypertension, assessment of cardiovascular and other hypertension-associated risk, and attainment of therapeutic goals. Chronobiol. Int. 2013, 30, 355-410. [CrossRef] [PubMed]
    • (2013) Chronobiol. Int , vol.30 , pp. 355-410
    • Hermida, R.C.1    Smolensky, M.H.2    Ayala, D.E.3    Portaluppi, F.4    Crespo, J.J.5    Fabbian, F.6    Haus, E.7    Manfredini, R.8    Mojón, A.9    Moyá, A.10
  • 75
    • 84958675065 scopus 로고    scopus 로고
    • Clinical value of ambulatory blood pressure: Is it time to recommend for all patients with hypertension?
    • [CrossRef] [PubMed]
    • Solak, Y., Kario, K., Covic, A., Bertelsen, N., Afsar, B., Ozkok, A., Wiecek, A., Kanbay, M. Clinical value of ambulatory blood pressure: Is it time to recommend for all patients with hypertension? Clin. Exp. Nephrol. 2016, 20, 14-22. [CrossRef] [PubMed]
    • (2016) Clin. Exp. Nephrol , vol.20 , pp. 14-22
    • Solak, Y.1    Kario, K.2    Covic, A.3    Bertelsen, N.4    Afsar, B.5    Ozkok, A.6    Wiecek, A.7    Kanbay, M.8
  • 76
    • 67649828065 scopus 로고    scopus 로고
    • Ambulatory blood pressure monitoring predicts cardiovascular events in treated hypertensive patients—An Anglo-Scandinavian cardiac outcomes trial substudy
    • [CrossRef] [PubMed]
    • Dolan, E., Stanton, A.V., Thom, S., Caulfield, M., Atkins, N., McInnes, G., Collier, D., Dicker, P., O’Brien, E. Ambulatory blood pressure monitoring predicts cardiovascular events in treated hypertensive patients—An Anglo-Scandinavian cardiac outcomes trial substudy. J. Hypertens. 2009, 27, 876-885. [CrossRef] [PubMed]
    • (2009) J. Hypertens , vol.27 , pp. 876-885
    • Dolan, E.1    Stanton, A.V.2    Thom, S.3    Caulfield, M.4    Atkins, N.5    McInnes, G.6    Collier, D.7    Dicker, P.8    O’Brien, E.9
  • 78
    • 0033709764 scopus 로고    scopus 로고
    • Systolic and Diastolic Blood Pressure, Pulse Pressure, and Mean Arterial Pressure as Predictors of Cardiovascular Disease Risk in Men
    • [CrossRef] [PubMed]
    • Sesso, H.D., Stampfer, M.J., Rosner, B., Hennekens, C.H., Gaziano, J.M., Manson, J.E., Glynn, R.J. Systolic and Diastolic Blood Pressure, Pulse Pressure, and Mean Arterial Pressure as Predictors of Cardiovascular Disease Risk in Men. Hypertension 2000, 36, 801-807. [CrossRef] [PubMed]
    • (2000) Hypertension , vol.36 , pp. 801-807
    • Sesso, H.D.1    Stampfer, M.J.2    Rosner, B.3    Hennekens, C.H.4    Gaziano, J.M.5    Manson, J.E.6    Glynn, R.J.7
  • 79
    • 33847096347 scopus 로고    scopus 로고
    • Blood pressure parameters and risk of fatal stroke, NHANES II mortality study
    • [CrossRef] [PubMed]
    • Brown, D.W., Giles, W.H., Greenlund, K.J. Blood pressure parameters and risk of fatal stroke, NHANES II mortality study. Am. J. Hypertens. 2007, 20, 338-341. [CrossRef] [PubMed]
    • (2007) Am. J. Hypertens , vol.20 , pp. 338-341
    • Brown, D.W.1    Giles, W.H.2    Greenlund, K.J.3
  • 80
    • 0035967471 scopus 로고    scopus 로고
    • Different prognostic impact of 24-hour mean blood pressure and pulse pressure on stroke and coronary artery disease in essential hypertension
    • [CrossRef] [PubMed]
    • Verdecchia, P., Schillaci, G., Reboldi, G., Franklin, S.S., Porcellati, C. Different prognostic impact of 24-hour mean blood pressure and pulse pressure on stroke and coronary artery disease in essential hypertension. Circulation 2001, 103, 2579-2584. [CrossRef] [PubMed]
    • (2001) Circulation , vol.103 , pp. 2579-2584
    • Verdecchia, P.1    Schillaci, G.2    Reboldi, G.3    Franklin, S.S.4    Porcellati, C.5
  • 82
    • 0032800958 scopus 로고    scopus 로고
    • Associations between heart rate and other risk factors in a large French population
    • [CrossRef] [PubMed]
    • Morcet, J.F., Safar, M., Thomas, F., Guize, L., Benetos, A. Associations between heart rate and other risk factors in a large French population. J. Hypertens. 1999, 17, 1671-1676. [CrossRef] [PubMed]
    • (1999) J. Hypertens , vol.17 , pp. 1671-1676
    • Morcet, J.F.1    Safar, M.2    Thomas, F.3    Guize, L.4    Benetos, A.5
  • 83
    • 67650141667 scopus 로고    scopus 로고
    • Heart rate as a risk factor for cardiovascular disease
    • [CrossRef] [PubMed]
    • Perret-Guillaume, C., Joly, L., Benetos, A. Heart rate as a risk factor for cardiovascular disease. Prog. Cardiovasc. Dis. 2009, 52, 6-10. [CrossRef] [PubMed]
    • (2009) Prog. Cardiovasc. Dis , vol.52 , pp. 6-10
    • Perret-Guillaume, C.1    Joly, L.2    Benetos, A.3
  • 84
    • 0032917162 scopus 로고    scopus 로고
    • Influence of Heart Rate on Mortality in a French Population
    • [CrossRef] [PubMed]
    • Benetos, A., Rudnichi, A., Thomas, F., Safar, M., Guize, L. Influence of Heart Rate on Mortality in a French Population. Hypertension 1999, 33, 44-52. [CrossRef] [PubMed]
    • (1999) Hypertension , vol.33 , pp. 44-52
    • Benetos, A.1    Rudnichi, A.2    Thomas, F.3    Safar, M.4    Guize, L.5
  • 85
    • 84870518727 scopus 로고    scopus 로고
    • Heart rate and blood pressure: Any possible implications for management of hypertension
    • [CrossRef] [PubMed]
    • Reule, S., Drawz, P.E. Heart rate and blood pressure: Any possible implications for management of hypertension? Curr. Hypertens. Rep. 2012, 14, 478-484. [CrossRef] [PubMed]
    • (2012) Curr. Hypertens. Rep , vol.14 , pp. 478-484
    • Reule, S.1    Drawz, P.E.2
  • 87
    • 84891616030 scopus 로고    scopus 로고
    • White-coat hypertension: New insights from recent studies
    • [CrossRef] [PubMed]
    • Franklin, S.S., Thijs, L., Hansen, T.W., O’Brien, E., Staessen, J.A. White-coat hypertension: New insights from recent studies. Hypertension 2013, 62, 982-987. [CrossRef] [PubMed]
    • (2013) Hypertension , vol.62 , pp. 982-987
    • Franklin, S.S.1    Thijs, L.2    Hansen, T.W.3    O’Brien, E.4    Staessen, J.A.5
  • 88
    • 84978906275 scopus 로고    scopus 로고
    • White-Coat Hypertension: A True Cardiovascular Risk?
    • [CrossRef] [PubMed]
    • Mani, A. White-Coat Hypertension: A True Cardiovascular Risk? J. Clin. Hypertens. 2016, 18, 623-624. [CrossRef] [PubMed]
    • (2016) J. Clin. Hypertens , vol.18 , pp. 623-624
    • Mani, A.1
  • 89
    • 78650272069 scopus 로고    scopus 로고
    • Prognostic value of white-coat and masked hypertension diagnosed by ambulatory monitoring in initially untreated subjects: An updated meta analysis
    • [CrossRef] [PubMed]
    • Pierdomenico, S.D., Cuccurullo, F. Prognostic value of white-coat and masked hypertension diagnosed by ambulatory monitoring in initially untreated subjects: An updated meta analysis. Am. J. Hypertens. 2011, 24, 52-58. [CrossRef] [PubMed]
    • (2011) Am. J. Hypertens. , vol.24 , pp. 52-58
    • Pierdomenico, S.D.1    Cuccurullo, F.2
  • 90
    • 84946739177 scopus 로고    scopus 로고
    • Target organ complications and cardiovascular events associated with masked hypertension and white-coat hypertension: Analysis from the dallas heart study
    • [CrossRef] [PubMed]
    • Tientcheu, D., Ayers, C., Das, S.R., McGuire, D.K., de Lemos, J.A., Khera, A., Kaplan, N., Victor, R., Vongpatanasin, W. Target organ complications and cardiovascular events associated with masked hypertension and white-coat hypertension: Analysis from the dallas heart study. J. Am. Coll. Cardiol. 2015, 66, 2159-2169. [CrossRef] [PubMed]
    • (2015) J. Am. Coll. Cardiol , vol.66 , pp. 2159-2169
    • Tientcheu, D.1    Ayers, C.2    Das, S.R.3    McGuire, D.K.4    De Lemos, J.A.5    Khera, A.6    Kaplan, N.7    Victor, R.8    Vongpatanasin, W.9
  • 91
    • 0348231661 scopus 로고    scopus 로고
    • White coat hypertension is a cardiovascular risk factor: A 10-year follow-up study
    • [CrossRef] [PubMed]
    • Gustavsen, P.H., Høegholm, A., Bang, L.E., Kristensen, K.S. White coat hypertension is a cardiovascular risk factor: A 10-year follow-up study. J. Hum. Hypertens. 2003, 17, 811-817. [CrossRef] [PubMed]
    • (2003) J. Hum. Hypertens , vol.17 , pp. 811-817
    • Gustavsen, P.H.1    Høegholm, A.2    Bang, L.E.3    Kristensen, K.S.4
  • 92
    • 84960409518 scopus 로고    scopus 로고
    • White-coat hypertension and cardiovascular events: A meta-analysis
    • [CrossRef] [PubMed]
    • Briasoulis, A., Androulakis, E., Palla, M., Papageorgiou, N., Tousoulis, D. White-coat hypertension and cardiovascular events: A meta-analysis. J. Hypertens. 2016, 34, 593-599. [CrossRef] [PubMed]
    • (2016) J. Hypertens. , vol.34 , pp. 593-599
    • Briasoulis, A.1    Roulakis, E.2    Palla, M.3    Papageorgiou, N.4    Tousoulis, D.5
  • 95
    • 84982133165 scopus 로고    scopus 로고
    • Blood pressure variability and cardiovascular disease: Systematic review and meta-analysis
    • [CrossRef] [PubMed]
    • Stevens, S.L., Wood, S., Koshiaris, C., Law, K., Glasziou, P., Stevens, R.J., McManus, R.J. Blood pressure variability and cardiovascular disease: Systematic review and meta-analysis. BMJ 2016, 354, i4098. [CrossRef] [PubMed]
    • (2016) BMJ , vol.354
    • Stevens, S.L.1    Wood, S.2    Koshiaris, C.3    Law, K.4    Glasziou, P.5    Stevens, R.J.6    McManus, R.J.7
  • 97
    • 84939225081 scopus 로고    scopus 로고
    • Ambulatory blood pressure monitoring in the diagnosis, prognosis, and management of resistant hypertension: Still a matter of our resistance?
    • [CrossRef] [PubMed]
    • Lazaridis, A.A., Sarafidis, P.A., Ruilope, L.M. Ambulatory blood pressure monitoring in the diagnosis, prognosis, and management of resistant hypertension: Still a matter of our resistance? Curr. Hypertens. Rep. 2015, 17, 78. [CrossRef] [PubMed]
    • (2015) Curr. Hypertens. Rep. , vol.17 , pp. 78
    • Lazaridis, A.A.1    Sarafidis, P.A.2    Ruilope, L.M.3
  • 99
    • 84979703362 scopus 로고    scopus 로고
    • Nocturnal non-dipping blood pressure profile in black normotensives is associated with cardiac target organ damage
    • [CrossRef] [PubMed]
    • Mezue, K., Isiguzo, G., Madu, C., Nwuruku, G., Rangaswami, J., Baugh, D., Madu, E. Nocturnal non-dipping blood pressure profile in black normotensives is associated with cardiac target organ damage. Ethn. Dis. 2016, 26, 279-284. [CrossRef] [PubMed]
    • (2016) Ethn. Dis , vol.26 , pp. 279-284
    • Mezue, K.1    Isiguzo, G.2    Madu, C.3    Nwuruku, G.4    Rangaswami, J.5    Baugh, D.6    Madu, E.7
  • 100
    • 0036853641 scopus 로고    scopus 로고
    • Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure: The Ohasama study
    • [CrossRef] [PubMed]
    • Ohkubo, T., Hozawa, A., Yamaguchi, J., Kikuya, M., Ohmori, K., Michimata, M., Matsubara, M., Hashimoto, J., Hoshi, H., Araki, T., et al. Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure: The Ohasama study. J. Hypertens. 2002, 20, 2183-2189. [CrossRef] [PubMed]
    • (2002) J. Hypertens , vol.20 , pp. 2183-2189
    • Ohkubo, T.1    Hozawa, A.2    Yamaguchi, J.3    Kikuya, M.4    Ohmori, K.5    Michimata, M.6    Matsubara, M.7    Hashimoto, J.8    Hoshi, H.9    Araki, T.10
  • 101
    • 84865809913 scopus 로고    scopus 로고
    • Day-night dip and early-morning surge in blood pressure in hypertension: Prognostic implications
    • [CrossRef] [PubMed]
    • Verdecchia, P., Angeli, F., Mazzotta, G., Garofoli, M., Ramundo, E., Gentile, G., Ambrosio, G., Reboldi, G. Day-night dip and early-morning surge in blood pressure in hypertension: Prognostic implications. Hypertension 2012, 60, 34-42. [CrossRef] [PubMed]
    • (2012) Hypertension , vol.60 , pp. 34-42
    • Verdecchia, P.1    Angeli, F.2    Mazzotta, G.3    Garofoli, M.4    Ramundo, E.5    Gentile, G.6    Ambrosio, G.7    Reboldi, G.8
  • 102
    • 70349437291 scopus 로고    scopus 로고
    • Night-day blood pressure ratio and dipping pattern as predictors of death and cardiovascular events in hypertension
    • [CrossRef] [PubMed]
    • Fagard, R.H., Thijs, L., Staessen, J.A., Clement, D.L., De Buyzere, M.L., De Bacquer, D.A. Night-day blood pressure ratio and dipping pattern as predictors of death and cardiovascular events in hypertension. J. Hum. Hypertens. 2009, 23, 645-653. [CrossRef] [PubMed]
    • (2009) J. Hum. Hypertens , vol.23 , pp. 645-653
    • Fagard, R.H.1    Thijs, L.2    Staessen, J.A.3    Clement, D.L.4    De Buyzere, M.L.5    De Bacquer, D.A.6
  • 103
    • 73249132939 scopus 로고    scopus 로고
    • Nocturnal nondipping of heart rate predicts cardiovascular events in hypertensive patients
    • [CrossRef] [PubMed]
    • Eguchi, K., Hoshide, S., Ishikawa, J., Pickering, T.G., Schwartz, J.E., Shimada, K., Kario, K. Nocturnal nondipping of heart rate predicts cardiovascular events in hypertensive patients. J. Hypertens. 2009, 27, 2265-2270. [CrossRef] [PubMed]
    • (2009) J. Hypertens , vol.27 , pp. 2265-2270
    • Eguchi, K.1    Hoshide, S.2    Ishikawa, J.3    Pickering, T.G.4    Schwartz, J.E.5    Shimada, K.6    Kario, K.7
  • 104
    • 0035726570 scopus 로고    scopus 로고
    • Stroke prognosis and abnormal nocturnal blood pressure falls in older hypertensives
    • [CrossRef] [PubMed]
    • Kario, K., Pickering, T.G., Matsuo, T., Hoshide, S., Schwartz, J.E., Shimada, K. Stroke prognosis and abnormal nocturnal blood pressure falls in older hypertensives. Hypertension 2001, 38, 852-857. [CrossRef] [PubMed]
    • (2001) Hypertension , vol.38 , pp. 852-857
    • Kario, K.1    Pickering, T.G.2    Matsuo, T.3    Hoshide, S.4    Schwartz, J.E.5    Shimada, K.6
  • 105
    • 84874170950 scopus 로고    scopus 로고
    • Blunted sleep-time relative blood pressure decline increases cardiovascular risk independent of blood pressure level—The “normotensive non-dipper” paradox
    • [CrossRef] [PubMed]
    • Hermida, R.C., Ayala, D.E., Mojón, A., Fernández, J.R. Blunted sleep-time relative blood pressure decline increases cardiovascular risk independent of blood pressure level—The “normotensive non-dipper” paradox. Chronobiol. Int. 2013, 30, 87-98. [CrossRef] [PubMed]
    • (2013) Chronobiol. Int , vol.30 , pp. 87-98
    • Hermida, R.C.1    Ayala, D.E.2    Mojón, A.3    Fernández, J.R.4
  • 106
    • 84960807835 scopus 로고    scopus 로고
    • Prognostic effect of the nocturnal blood pressure fall in hypertensive patients: The ambulatory blood pressure collaboration in patients with hypertension (ABC-H) meta-analysis
    • [CrossRef] [PubMed]
    • Salles, G.F., Reboldi, G., Fagard, R.H., Cardoso, C.R.L., Pierdomenico, S.D., Verdecchia, P., Eguchi, K., Kario, K., Hoshide, S., Polonia, J., et al. Prognostic effect of the nocturnal blood pressure fall in hypertensive patients: The ambulatory blood pressure collaboration in patients with hypertension (ABC-H) meta-analysis. Hypertension 2016, 67, 693-700. [CrossRef] [PubMed]
    • (2016) Hypertension , vol.67 , pp. 693-700
    • Salles, G.F.1    Reboldi, G.2    Fagard, R.H.3    Cardoso, C.R.L.4    Pierdomenico, S.D.5    Verdecchia, P.6    Eguchi, K.7    Kario, K.8    Hoshide, S.9    Polonia, J.10
  • 108
    • 84922964850 scopus 로고    scopus 로고
    • Prognostic value of morning blood pressure surge in clinical events: A meta-analysis of longitudinal studies
    • [CrossRef] [PubMed]
    • Xie, J.C., Yan, H., Zhao, Y.X., Liu, X.Y. Prognostic value of morning blood pressure surge in clinical events: A meta-analysis of longitudinal studies. J. Stroke Cerebrovasc. Dis. 2015, 24, 362-369. [CrossRef] [PubMed]
    • (2015) J. Stroke Cerebrovasc. Dis , vol.24 , pp. 362-369
    • Xie, J.C.1    Yan, H.2    Zhao, Y.X.3    Liu, X.Y.4
  • 111
    • 84974695995 scopus 로고    scopus 로고
    • Does sympathetic overactivation feature all hypertensives? Differences of sympathovagal balance according to night/day blood pressure ratio in patients with essential hypertension
    • [CrossRef] [PubMed]
    • Di Raimondo, D., Miceli, G., Casuccio, A., Tuttolomondo, A., Buttà, C., Zappulla, V., Schimmenti, C., Musiari, G., Pinto, A. Does sympathetic overactivation feature all hypertensives? Differences of sympathovagal balance according to night/day blood pressure ratio in patients with essential hypertension. Hypertens. Res. 2016, 39, 1-9. [CrossRef] [PubMed]
    • (2016) Hypertens. Res , vol.39 , pp. 1-9
    • Di Raimondo, D.1    Miceli, G.2    Casuccio, A.3    Tuttolomondo, A.4    Buttà, C.5    Zappulla, V.6    Schimmenti, C.7    Musiari, G.8    Pinto, A.9
  • 112
    • 84896313456 scopus 로고    scopus 로고
    • The role of autonomic and baroreceptor reflex control in blood pressure dipping and nondipping in rats
    • [CrossRef] [PubMed]
    • Kuo, T.B.J., Chen, C.-Y., Wang, Y.P., Lan, Y.-Y., Mak, K.-H., Lee, G.-S., Yang, C.C.H. The role of autonomic and baroreceptor reflex control in blood pressure dipping and nondipping in rats. J. Hypertens. 2014, 32, 806-816. [CrossRef] [PubMed]
    • (2014) J. Hypertens , vol.32 , pp. 806-816
    • Kuo, T.B.J.1    Chen, C.-Y.2    Wang, Y.P.3    Lan, Y.-Y.4    Mak, K.-H.5    Lee, G.-S.6    Yang, C.C.H.7
  • 113
    • 85044097919 scopus 로고    scopus 로고
    • Blunted nightly blood pressure reduction is associated with increased arterial stiffness in ischemic stroke patients: A Norwegian stroke in the young study
    • [CrossRef] [PubMed]
    • Saeed, S., Wajea-Andreassen, U., Fromm, A., Øygarden, H., Naess, H., Gerdts, E. Blunted nightly blood pressure reduction is associated with increased arterial stiffness in ischemic stroke patients: A Norwegian stroke in the young study. J. Hypertens. 2015, 33, e41. [CrossRef] [PubMed]
    • (2015) J. Hypertens , vol.33
    • Saeed, S.1    Wajea-Andreassen, U.2    Fromm, A.3    Øygarden, H.4    Naess, H.5    Gerdts, E.6
  • 114
    • 84941197322 scopus 로고    scopus 로고
    • Nitroglycerin-mediated, but not flow-mediated vasodilation, is associated with blunted nocturnal blood pressure fall in patients with resistant hypertension
    • [CrossRef] [PubMed]
    • Fontes-Guerra, P.C.A., Cardoso, C.R.L., Muxfeldt, E.S., Salles, G.F. Nitroglycerin-mediated, but not flow-mediated vasodilation, is associated with blunted nocturnal blood pressure fall in patients with resistant hypertension. J. Hypertens. 2015, 33, 1666-1675. [CrossRef] [PubMed]
    • (2015) J. Hypertens , vol.33 , pp. 1666-1675
    • Fontes-Guerra, P.C.A.1    Cardoso, C.R.L.2    Muxfeldt, E.S.3    Salles, G.F.4
  • 115
    • 34047201525 scopus 로고    scopus 로고
    • Ambulatory blood pressure and cardiovascular outcome in relation to perceived sleep deprivation
    • [CrossRef] [PubMed]
    • Verdecchia, P., Angeli, F., Borgioni, C., Gattobigio, R., Reboldi, G. Ambulatory blood pressure and cardiovascular outcome in relation to perceived sleep deprivation. Hypertension 2007, 49, 777-783. [CrossRef] [PubMed]
    • (2007) Hypertension , vol.49 , pp. 777-783
    • Verdecchia, P.1    Angeli, F.2    Borgioni, C.3    Gattobigio, R.4    Reboldi, G.5
  • 116
    • 84946558752 scopus 로고    scopus 로고
    • Reproducibility of ambulatory blood pressure values and circadian blood pressure patterns in untreated subjects in a 1-11 month interval
    • [CrossRef] [PubMed]
    • Monte, M., Cambão, M., Mesquita Bastos, J., Polónia, J. Reproducibility of ambulatory blood pressure values and circadian blood pressure patterns in untreated subjects in a 1-11 month interval. Rev. Port. Cardiol. 2015, 34, 643-650. [CrossRef] [PubMed]
    • (2015) Rev. Port. Cardiol. , vol.34 , pp. 643-650
    • Monte, M.1    Cambão, M.2    Mesquita Bastos, J.3    Polónia, J.4
  • 117
    • 84945447900 scopus 로고    scopus 로고
    • Limited reproducibility of 24-h ambulatory blood pressure monitoring
    • [PubMed]
    • Keren, S., Leibowitz, A., Grossman, E., Sharabi, Y. Limited reproducibility of 24-h ambulatory blood pressure monitoring. Clin. Exp. Hypertens. 2015, 37, 599-603. [PubMed]
    • (2015) Clin. Exp. Hypertens , vol.37 , pp. 599-603
    • Keren, S.1    Leibowitz, A.2    Grossman, E.3    Sharabi, Y.4
  • 118
    • 37349007842 scopus 로고    scopus 로고
    • Chronotherapy improves blood pressure control and reverts the nondipper pattern in patients with resistant hypertension
    • [CrossRef] [PubMed]
    • Hermida, R.C., Ayala, D.E., Fernández, J.R., Calvo, C. Chronotherapy improves blood pressure control and reverts the nondipper pattern in patients with resistant hypertension. Hypertension 2008, 51, 69-76. [CrossRef] [PubMed]
    • (2008) Hypertension , vol.51 , pp. 69-76
    • Hermida, R.C.1    Ayala, D.E.2    Fernández, J.R.3    Calvo, C.4
  • 122
    • 15744396114 scopus 로고    scopus 로고
    • Impact of obesity on 24-hour ambulatory blood pressure and hypertension
    • [CrossRef] [PubMed]
    • Kotsis, V., Stabouli, S., Bouldin, M., Low, A., Toumanidis, S., Zakopoulos, N. Impact of obesity on 24-hour ambulatory blood pressure and hypertension. Hypertension 2005, 45, 602-607. [CrossRef] [PubMed]
    • (2005) Hypertension , vol.45 , pp. 602-607
    • Kotsis, V.1    Stabouli, S.2    Bouldin, M.3    Low, A.4    Toumanidis, S.5    Zakopoulos, N.6
  • 123
    • 57149145464 scopus 로고    scopus 로고
    • Body mass index, nocturnal fall in blood pressure and organ damage in untreated essential hypertensive patients
    • [CrossRef] [PubMed]
    • Cuspidi, C., Meani, S., Valerio, C., Negri, F., Sala, C., Maisaidi, M., Giudici, V., Zanchetti, A., Mancia, G. Body mass index, nocturnal fall in blood pressure and organ damage in untreated essential hypertensive patients. Blood Press. Monit. 2008, 13, 318-324. [CrossRef] [PubMed]
    • (2008) Blood Press. Monit , vol.13 , pp. 318-324
    • Cuspidi, C.1    Meani, S.2    Valerio, C.3    Negri, F.4    Sala, C.5    Maisaidi, M.6    Giudici, V.7    Zanchetti, A.8    Mancia, G.9
  • 124
    • 84871727418 scopus 로고    scopus 로고
    • Relationship between vitamin D deficiency and nondipper hypertension
    • [CrossRef] [PubMed]
    • Demir, M., Günay, T., Özmen, G., Melek, M. Relationship between vitamin D deficiency and nondipper hypertension. Clin. Exp. Hypertens. 2013, 35, 45-49. [CrossRef] [PubMed]
    • (2013) Clin. Exp. Hypertens , vol.35 , pp. 45-49
    • Demir, M.1    Günay, T.2    Özmen, G.3    Melek, M.4
  • 125
  • 126
    • 34748924246 scopus 로고    scopus 로고
    • Relation between serum calcium, phosphate, parathyroid hormone and “nondipper” circadian blood pressure variability profile in patients with normal renal function
    • [CrossRef] [PubMed]
    • Kanbay, M., Isik, B., Akcay, A., Ozkara, A., Karakurt, F., Turgut, F., Alkan, R., Uz, E., Bavbek, N., Yigitoglu, R., et al. Relation between serum calcium, phosphate, parathyroid hormone and “nondipper” circadian blood pressure variability profile in patients with normal renal function. Am. J. Nephrol. 2007, 27, 516-521. [CrossRef] [PubMed]
    • (2007) Am. J. Nephrol , vol.27 , pp. 516-521
    • Kanbay, M.1    Isik, B.2    Akcay, A.3    Ozkara, A.4    Karakurt, F.5    Turgut, F.6    Alkan, R.7    Uz, E.8    Bavbek, N.9    Yigitoglu, R.10
  • 127
    • 0032887195 scopus 로고    scopus 로고
    • Effect of dietary patterns on ambulatory blood pressure: Results from the dietary approaches to stop hypertension (DASH) trial. DASH collaborative research group
    • [CrossRef] [PubMed]
    • Moore, T.J., Vollmer, W.M., Appel, L.J., Sacks, F.M., Svetkey, L.P., Vogt, T.M., Conlin, P.R., Simons-Morton, D.G., Carter-Edwards, L., Harsha, D.W. Effect of dietary patterns on ambulatory blood pressure: Results from the dietary approaches to stop hypertension (DASH) trial. DASH collaborative research group. Hypertension 1999, 34, 472-477. [CrossRef] [PubMed]
    • (1999) Hypertension , vol.34 , pp. 472-477
    • Moore, T.J.1    Vollmer, W.M.2    Appel, L.J.3    Sacks, F.M.4    Svetkey, L.P.5    Vogt, T.M.6    Conlin, P.R.7    Simons-Morton, D.G.8    Carter-Edwards, L.9    Harsha, D.W.10
  • 129
    • 84945478755 scopus 로고    scopus 로고
    • Effects of the DASH diet and walking on blood pressure in patients with type 2 diabetes and uncontrolled hypertension: A randomized controlled trial
    • [CrossRef] [PubMed]
    • Paula, T.P., Viana, L.V., Neto, A.T.Z., Leitão, C.B., Gross, J.L., Azevedo, M.J. Effects of the DASH diet and walking on blood pressure in patients with type 2 diabetes and uncontrolled hypertension: A randomized controlled trial. J. Clin. Hypertens. 2015, 17, 895-901. [CrossRef] [PubMed]
    • (2015) J. Clin. Hypertens , vol.17 , pp. 895-901
    • Paula, T.P.1    Viana, L.V.2    Neto, A.T.Z.3    Leitão, C.B.4    Gross, J.L.5    Azevedo, M.J.6
  • 131
    • 84903518377 scopus 로고    scopus 로고
    • Hypotensive effects of solitary addition of conventional nonfat dairy products to the routine diet: A randomized controlled trial
    • [CrossRef] [PubMed]
    • Machin, D.R., Park, W., Alkatan, M., Mouton, M., Tanaka, H. Hypotensive effects of solitary addition of conventional nonfat dairy products to the routine diet: A randomized controlled trial. Am. J. Clin. Nutr. 2014, 100, 80-87. [CrossRef] [PubMed]
    • (2014) Am. J. Clin. Nutr , vol.100 , pp. 80-87
    • Machin, D.R.1    Park, W.2    Alkatan, M.3    Mouton, M.4    Tanaka, H.5
  • 132
    • 84883272189 scopus 로고    scopus 로고
    • Lovegrove, J.A. Acute ingestion of beetroot bread increases endothelium-independent vasodilation and lowers diastolic blood pressure in healthy men: A randomized controlled trial
    • [CrossRef] [PubMed]
    • Hobbs, D.A., Goulding, M.G., Nguyen, A., Malaver, T., Walker, C.F., George, T.W., Methven, L., Lovegrove, J.A. Acute ingestion of beetroot bread increases endothelium-independent vasodilation and lowers diastolic blood pressure in healthy men: A randomized controlled trial. J. Nutr. 2013, 143, 1399-1405. [CrossRef] [PubMed]
    • (2013) J. Nutr , vol.143 , pp. 1399-1405
    • Hobbs, D.A.1    Goulding, M.G.2    Nguyen, A.3    Malaver, T.4    Walker, C.F.5    George, T.W.6    Methven, L.7
  • 133
    • 84927697763 scopus 로고    scopus 로고
    • Beetroot supplementation lowers daily systolic blood pressure in older, overweight subjects
    • [CrossRef] [PubMed]
    • Jajja, A., Sutyarjoko, A., Lara, J., Rennie, K., Brandt, K., Qadir, O., Siervo, M. Beetroot supplementation lowers daily systolic blood pressure in older, overweight subjects. Nutr. Res. 2014, 34, 868-875. [CrossRef] [PubMed]
    • (2014) Nutr. Res , vol.34 , pp. 868-875
    • Jajja, A.1    Sutyarjoko, A.2    Lara, J.3    Rennie, K.4    Brandt, K.5    Qadir, O.6    Siervo, M.7
  • 134
    • 84921543574 scopus 로고    scopus 로고
    • Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study
    • [CrossRef] [PubMed]
    • Kapil, V., Khambata, R.S., Robertson, A., Caulfield, M.J., Ahluwalia, A. Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study. Hypertension 2015, 65, 320-327. [CrossRef] [PubMed]
    • (2015) Hypertension , vol.65 , pp. 320-327
    • Kapil, V.1    Khambata, R.S.2    Robertson, A.3    Caulfield, M.J.4    Ahluwalia, A.5
  • 135
    • 84870717622 scopus 로고    scopus 로고
    • Effect of beetroot juice on lowering blood pressure in free-living, disease-free adults: A randomized, placebo-controlled trial
    • [CrossRef] [PubMed]
    • Coles, L.T., Clifton, P.M. Effect of beetroot juice on lowering blood pressure in free-living, disease-free adults: A randomized, placebo-controlled trial. Nutr. J. 2012, 11, 1-6. [CrossRef] [PubMed]
    • (2012) Nutr. J. , vol.11 , pp. 1-6
    • Coles, L.T.1    Clifton, P.M.2
  • 136
    • 84867741242 scopus 로고    scopus 로고
    • Effect of cholecalciferol supplementation during winter months in patients with hypertension: A randomized, placebo-controlled trial
    • [CrossRef] [PubMed]
    • Larsen, T., Mose, F.H., Bech, J.N., Hansen, A.B., Pedersen, E.B. Effect of cholecalciferol supplementation during winter months in patients with hypertension: A randomized, placebo-controlled trial. Am. J. Hypertens. 2012, 25, 1215-1222. [CrossRef] [PubMed]
    • (2012) Am. J. Hypertens , vol.25 , pp. 1215-1222
    • Larsen, T.1    Mose, F.H.2    Bech, J.N.3    Hansen, A.B.4    Pedersen, E.B.5
  • 138
    • 84944171066 scopus 로고    scopus 로고
    • Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (Pre-)hypertension: A randomised double-blinded placebo-controlled cross-over trial
    • [CrossRef] [PubMed]
    • Brüll, V., Burak, C., Stoffel-Wagner, B., Wolffram, S., Nickenig, G., Müller, C., Langguth, P., Alteheld, B., Fimmers, R., Naaf, S., et al. Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: A randomised double-blinded placebo-controlled cross-over trial. Br. J. Nutr. 2015, 14, 1263-1277. [CrossRef] [PubMed]
    • (2015) Br. J. Nutr , vol.14 , pp. 1263-1277
    • Brüll, V.1    Burak, C.2    Stoffel-Wagner, B.3    Wolffram, S.4    Nickenig, G.5    Müller, C.6    Langguth, P.7    Alteheld, B.8    Fimmers, R.9    Naaf, S.10
  • 139
    • 84937806010 scopus 로고    scopus 로고
    • Pistachio nut consumption modifies systemic hemodynamics, increases heart rate variability, and reduces ambulatory blood pressure in well-controlled type 2 diabetes: A randomized trial
    • [CrossRef] [PubMed]
    • Sauder, K.A., McCrea, C.E., Ulbrecht, J.S., Kris-Etherton, P.M., West, S.G. Pistachio nut consumption modifies systemic hemodynamics, increases heart rate variability, and reduces ambulatory blood pressure in well-controlled type 2 diabetes: A randomized trial. J. Am. Heart Assoc. 2014, 3, 1-9. [CrossRef] [PubMed]
    • (2014) J. Am. Heart Assoc , vol.3 , pp. 1-9
    • Sauder, K.A.1    McCrea, C.E.2    Ulbrecht, J.S.3    Kris-Etherton, P.M.4    West, S.G.5
  • 141
    • 84939897308 scopus 로고    scopus 로고
    • Folate administration decreases oxidative status and blood pressure in postmenopausal women
    • [CrossRef] [PubMed]
    • Cagnacci, A., Cannoletta, M., Xholli, A., Piacenti, I., Palma, F., Palmieri, B. Folate administration decreases oxidative status and blood pressure in postmenopausal women. Eur. J. Nutr. 2015, 54, 429-435. [CrossRef] [PubMed]
    • (2015) Eur. J. Nutr , vol.54 , pp. 429-435
    • Cagnacci, A.1    Cannoletta, M.2    Xholli, A.3    Piacenti, I.4    Palma, F.5    Palmieri, B.6
  • 142
    • 70350029201 scopus 로고    scopus 로고
    • High-dose short-term folate administration modifies ambulatory blood pressure in postmenopausal women. A placebo-controlled study
    • [CrossRef] [PubMed]
    • Cagnacci, A., Cannoletta, M., Volpe, A. High-dose short-term folate administration modifies ambulatory blood pressure in postmenopausal women. A placebo-controlled study. Eur. J. Clin. Nutr. 2009, 63, 1266-1268. [CrossRef] [PubMed]
    • (2009) Eur. J. Clin. Nutr , vol.63 , pp. 1266-1268
    • Cagnacci, A.1    Cannoletta, M.2    Volpe, A.3
  • 143
    • 23444452249 scopus 로고    scopus 로고
    • Folic acid supplementation for 3 weeks reduces pulse pressure and large artery stiffness independent of MTHFR genotype
    • [PubMed]
    • Williams, C., Kingwell, B.A., Burke, K., McPherson, J., Dart, A.M. Folic acid supplementation for 3 weeks reduces pulse pressure and large artery stiffness independent of MTHFR genotype. Am. J. Clin. Nutr. 2005, 82, 26-31. [PubMed]
    • (2005) Am. J. Clin. Nutr. , vol.82 , pp. 26-31
    • Williams, C.1    Kingwell, B.A.2    Burke, K.3    McPherson, J.4    Dart, A.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.