Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: Updated systematic review and meta-analysis

The Lancet

Volumn 387, Issue 10017, 2016, Pages 435-443

  Xie, Xinfang ^a   Atkins, Emily ^b   Lv, Jicheng ^a,b   Bennett, Alexander ^b   Neal, Bruce ^b   Ninomiya, Toshiharu ^d   Woodward, Mark ^b,c   MacMahon, Stephen ^b,c   Turnbull, Fiona ^b   Hillis, Graham S ^e   Chalmers, John ^b   Mant, Jonathan ^f   Salam, Abdul ^b   Rahimi, Kazem ^c   Perkovic, Vlado ^b   Rodgers, Anthony ^b  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d KYUSHU UNIVERSITY   (Japan)

^e ROYAL PERTH HOSPITAL   (Australia)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT;

ALBUMINURIA; BLOOD PRESSURE REGULATION; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CAUSE OF DEATH; CEREBROVASCULAR ACCIDENT; DATA BASE; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; DISEASE COURSE; END STAGE RENAL DISEASE; FOLLOW UP; HEART FAILURE; HEART INFARCTION; HUMAN; HYPOTENSION; KIDNEY DISEASE; MEAN ARTERIAL PRESSURE; META ANALYSIS; MORTALITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RETINOPATHY; REVIEW; RISK FACTOR; SYSTEMATIC REVIEW; SYSTOLIC BLOOD PRESSURE; AUSTRALIA; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; CHRONIC KIDNEY FAILURE; COMPLICATION; DRUG EFFECTS; HYPERTENSION; HYPERTENSIVE RETINOPATHY; INTENSIVE CARE; PATHOPHYSIOLOGY; PRACTICE GUIDELINE; PROCEDURES; STANDARDS; TREATMENT OUTCOME;

ALBUMINURIA; ANTIHYPERTENSIVE AGENTS; AUSTRALIA; BLOOD PRESSURE; BLOOD PRESSURE DETERMINATION; CRITICAL CARE; HUMANS; HYPERTENSION; HYPERTENSIVE RETINOPATHY; KIDNEY FAILURE, CHRONIC; MYOCARDIAL INFARCTION; PRACTICE GUIDELINES AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; STROKE; TREATMENT OUTCOME;

EID: 84959363424     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(15)00805-3     Document Type: Article

References (40)

1. PA James, S Oparil, BL Carter et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8) JAMA 311 2014 507 520
2. G Mancia, R Fagard, K Narkiewicz et al. 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) Blood Press 22 2013 193 278
3. National Institute for Health and Care Excellence The clinical management of primary hypertension in adults: clinical guideline 127 2011 NICE London
4. A Rodgers, M Ezzati, S Vander Hoorn et al. Distribution of major health risks: findings from the Global Burden of Disease Study PLoS Med 1 2004 e27
5. AJ Kerr, J Broad, S Wells, T Riddell, R Jackson Should the first priority in cardiovascular risk management be those with prior cardiovascular disease? Heart 95 2009 125 129
6. ACCORD Study Group Effects of intensive blood-pressure control in type 2 diabetes mellitus N Engl J Med 362 2010 1575
7. JC Lv, B Neal, P Ehteshami et al. Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis PLoS Med 9 2012 e1001293
8. K Asayama, T Ohkubo, H Metoki et al. Cardiovascular outcomes in the first trial of antihypertensive therapy guided by self-measured home blood pressure Hypertens Res 35 2012 1102 1110
9. OR Benavente, CS Coffey, R Conwit et al. Blood-pressure targets in patients with recent lacunar stroke: the SPS3 randomised trial Lancet 382 2013 507 515
10. Y Wei, Z Jin, G Shen et al. Effects of intensive antihypertensive treatment on Chinese hypertensive patients older than 70 years J Clin Hypertens 15 2013 420 427
11. A Liberati, DG Altman, J Tetzlaff et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration Ann Intern Med 151 2009 W65 W94
12. M Woodward Epidemiology: design and data analysis 2nd edn 2005 Chapman and Hall/CRC Press Boca Raton, FL
13. RD Toto, HC Mitchell, RD Smith et al. "Strict" blood pressure control and progression of renal disease in hypertensive nephrosclerosis Kidney Int 48 1995 851 859
14. L Hansson, A Zanchetti, SG Carruthers et al. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. HOT Study Group Lancet 351 1998 1755 1762
15. UK Prospective Diabetes Study Group Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 BMJ 317 1998 703 713
16. RO Estacio, BW Jeffers, N Gifford, RW Schrier Effect of blood pressure control on diabetic microvascular complications in patients with hypertension and type 2 diabetes Diabetes Care 23 (suppl 2) 2000 B54 B64
17. RW Schrier, RO Estacio, A Esler, P Mehler Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes Kidney Int 61 2002 1086 1097
18. R Schrier, K McFann, A Johnson et al. Cardiac and renal effects of standard versus rigorous blood pressure control in autosomal-dominant polycystic kidney disease: results of a seven-year prospective randomized study J Am Soc Nephrol 13 2002 1733 1739
19. LJ Appel, JT Wright Jr, T Greene et al. Intensive blood-pressure control in hypertensive chronic kidney disease N Engl J Med 363 2010 918 929
20. MJ Sarnak, T Greene, X Wang et al. The effect of a lower target blood pressure on the progression of kidney disease: long-term follow-up of the modification of diet in renal disease study Ann Intern Med 142 2005 342 351
21. P Ruggenenti, A Perna, G Loriga et al. Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial Lancet 365 2005 939 946
22. RO Estacio, JR Coll, ZV Tran, RW Schrier Effect of intensive blood pressure control with valsartan on urinary albumin excretion in normotensive patients with type 2 diabetes Am J Hypertens 19 2006 1241 1248
23. JATOS Study Group Principal results of the Japanese trial to assess optimal systolic blood pressure in elderly hypertensive patients (JATOS) Hypertens Res 31 2008 2115 2127
24. P Verdecchia, JA Staessen, F Angeli et al. Usual versus tight control of systolic blood pressure in non-diabetic patients with hypertension (Cardio-Sis): an open-label randomised trial Lancet 374 2009 525 533
25. E Wuhl, A Trivelli, S Picca et al. Strict blood-pressure control and progression of renal failure in children N Engl J Med 361 2009 1639 1650
26. T Ogihara, T Saruta, H Rakugi et al. Target blood pressure for treatment of isolated systolic hypertension in the elderly: valsartan in elderly isolated systolic hypertension study Hypertension 56 2010 196 202
27. S Lewington, R Clarke, N Qizilbash, R Peto, R Collins Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies Lancet 360 2002 1903 1913
28. MR Law, JK Morris, NJ Wald Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies BMJ 338 2009 b1665
29. AM Thompson, T Hu, CL Eshelbrenner et al. Antihypertensive treatment and secondary prevention of cardiovascular disease events among persons without hypertension: a meta-analysis JAMA 305 2011 913 922
30. JA Arguedas, MI Perez, JM Wright Treatment blood pressure targets for hypertension Cochrane Database Syst Rev 3 2009 CD004349
31. S MacMahon, R Peto, J Cutler et al. Blood pressure, stroke, and coronary heart disease. Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias Lancet 335 1990 765 774
32. CM Lawes, A Rodgers, DA Bennett et al. Blood pressure and cardiovascular disease in the Asia Pacific region J Hypertens 21 2003 707 716
33. J Chalmers Is a blood pressure target of <130/80 mm Hg still appropriate for high-risk patients? Circulation 124 2011 1700 1702
34. D Jacobs, H Blackburn, M Higgins et al. Report of the Conference on Low Blood Cholesterol: mortality associations Circulation 86 1992 1046 1060
35. Cholesterol Treatment Trialists' (CTT) Collaboration Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins Lancet 366 2005 1267 1278
36. J Warwick, E Falaschetti, K Rockwood et al. No evidence that frailty modifies the positive impact of antihypertensive treatment in very elderly people: an investigation of the impact of frailty upon treatment effect in the HYpertension in the Very Elderly Trial (HYVET) study, a double-blind, placebo-controlled study of antihypertensives in people with hypertension aged 80 and over BMC Med 13 2015 78
37. R Peters, N Beckett, L Burch et al. The effect of treatment based on a diuretic (indapamide)±ACE inhibitor (perindopril) on fractures in the Hypertension in the Very Elderly Trial (HYVET) Age Ageing 39 2010 609 616
38. DS Wald, M Law, JK Morris, JP Bestwick, NJ Wald Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials Am J Med 122 2009 290 300
39. MR Law, NJ Wald, JK Morris, RE Jordan Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials BMJ 326 2003 1427
40. RD Feldman, GY Zou, MK Vandervoort et al. A simplified approach to the treatment of uncomplicated hypertension: a cluster randomized, controlled trial Hypertension 53 2009 646 653