Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation

Journal of Nutritional Biochemistry

Volumn 39, Issue , 2017, Pages 145-155

  Tylichová, Zuzana ^a,b   Straková, Nicol ^a,c   Vondráček, Jan ^a,b   Vaculová, Alena Hyršlová ^a   Kozubík, Alois ^a,b   Hofmanová, Jiřina ^a,b  

^a INSTITUTE OF MATHEMATICS   (Czech Republic)

^b MASARYK UNIVERSITY   (Czech Republic)

^c ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

Author keywords

Autophagy; Butyrate; Colon cancer; Differentiation; Docosahexaenoic acid; PPAR

Indexed keywords

ALKALINE PHOSPHATASE; APOPTOSIS REGULATORY PROTEIN; BUTYRIC ACID; CASPASE 3; DOCOSAHEXAENOIC ACID; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BAK; PROTEIN BID; PROTEIN MCL 1; PROTEIN P62; X LINKED INHIBITOR OF APOPTOSIS; ANTINEOPLASTIC AGENT; BUTYRIC ACID DERIVATIVE; CASP3 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL PROTECTION; COLON ADENOCARCINOMA; COLON CARCINOMA; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HCT116 CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; COLON TUMOR; DRUG EFFECTS; GENETICS; HCT 116 CELL LINE; HT-29 CELL LINE; METABOLISM; PATHOLOGY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BUTYRATES; BUTYRIC ACID; CASPASE 3; CELL DIFFERENTIATION; COLONIC NEOPLASMS; DOCOSAHEXAENOIC ACIDS; HCT116 CELLS; HT29 CELLS; HUMANS; MITOCHONDRIA; PPAR GAMMA;

EID: 84995481713     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2016.09.006     Document Type: Article

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