Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation

Experimental Biology and Medicine

Volumn 239, Issue 3, 2014, Pages 302-310

  Cho, Youngmi ^a   Turner, Nancy D ^a   Davidson, Laurie A ^a   Chapkin, Robert S ^a   Carroll, Raymond J ^a   Lupton, Joanne R ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

apoptosis; butyrate; DNA methylation; docosahexaenoic acid; epigenetics

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BUTYRIC ACID; DEATH RECEPTOR 3; DOCOSAHEXAENOIC ACID; HISTONE H3; HISTONE H4; LINOLEIC ACID; PROTEIN BCL 2;

ACETYLATION; APOPTOSIS; ARTICLE; COLON CANCER; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

APOPTOSIS; BUTYRATE; DNA METHYLATION; DOCOSAHEXAENOIC ACID; EPIGENETICS;

ACETYLATION; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AZACITIDINE; BUTYRATES; CELL LINE, TUMOR; COLONIC NEOPLASMS; DEATH-ASSOCIATED PROTEIN KINASES; DNA METHYLATION; DNA MODIFICATION METHYLASES; DOCOSAHEXAENOIC ACIDS; HCT116 CELLS; HISTONES; HUMANS; LINOLEIC ACID; LYMPHOTOXIN BETA RECEPTOR; MEMBRANE PROTEINS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 25; TRANSCRIPTION, GENETIC;

EID: 84896037211     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370213514927     Document Type: Article

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