Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth

Cell Metabolism

Volumn 24, Issue 5, 2016, Pages 685-700

  Yang, Lifeng ^a,b   Achreja, Abhinav ^a,b   Yeung, Tsz Lun ^d   Mangala, Lingegowda S ^d   Jiang, Dahai ^d   Han, Cecil ^d   Baddour, Joelle ^a,b   Marini, Juan C ^c   Ni, Joseph ^a,b   Nakahara, Ryuichi ^a,b   Wahlig, Stephen ^a,b   Chiba, Lisa ^a,b   Kim, Sun Hye ^a,b   Morse, Joshua ^a   Pradeep, Sunila ^d   Nagaraja, Archana Sidalaghatta ^d   Haemmerle, Monika ^d   Kyunghee, Noh ^d,e   Derichsweiler, Mathew ^a,b   Plackemeier, Thomas ^a,b   Mercado Uribe, Imelda ^d   Lopez Berestein, Gabriel ^d   Moss, Tyler ^d   Ram, Prahlad T ^d   Liu, Jinsong ^d   Lu, Xiongbin ^d   Mok, Samuel C ^d   Sood, Anil K ^d   Nagrath, Deepak ^a,b   more..

^a RICE UNIVERSITY   (United States)

^b Rice University   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS   (United States)

^e Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; ASPARTIC ACID; GLUTAMATE AMMONIA LIGASE; GLUTAMINE; AMINO ACID; ASPARTATE AMINOTRANSFERASE; CARBON; NITROGEN; NUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CELL METABOLISM; CITRIC ACID CYCLE; CONTROLLED STUDY; FEMALE; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STROMA CELL; TUMOR MICROENVIRONMENT; TUMOR VOLUME; UPREGULATION; ANIMAL; CANCER ASSOCIATED FIBROBLAST; CELL PROLIFERATION; DISEASE MODEL; ENZYMOLOGY; EPITHELIUM CELL; HUMAN; METABOLISM; METABOLOME; NEOPLASM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

AMINO ACIDS; ANIMALS; ASPARTATE AMINOTRANSFERASES; CANCER-ASSOCIATED FIBROBLASTS; CARBON; CELL LINE, TUMOR; CELL PROLIFERATION; CITRIC ACID CYCLE; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; GLUTAMATE-AMMONIA LIGASE; HUMANS; METABOLOME; MICE, NUDE; NEOPLASMS; NITROGEN; NUCLEOTIDES; STROMAL CELLS; TUMOR MICROENVIRONMENT; UP-REGULATION;

EID: 84994680371     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.10.011     Document Type: Article

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