Glutamine synthetase is a genetic determinant of cell type-specific glutamine independence in breast epithelia

PLoS Genetics

Volumn 7, Issue 8, 2011, Pages

  Kung, Hsiu Ni ^a,b   Marks, Jeffrey R ^a   Chi, Jen Tsan ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINE; GATA3 PROTEIN, HUMAN; GLUTAMATE AMMONIA LIGASE; GLUTAMINASE; TRANSCRIPTION FACTOR GATA 3;

ARTICLE; BASAL CELL; BINDING KINETICS; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL CULTURE; CANCER CLASSIFICATION; CELL SPECIFICITY; COCULTURE; CONTROLLED STUDY; GATA3 GENE; GENE; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GLUTAMATE AMMONIA LIGASE GENE; GLUTAMINE SYNTHETASE GENE; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOLECULAR PHYLOGENY; ONCOGENE; PHENOTYPE; PROMOTER REGION; BREAST; BREAST TUMOR; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL SURVIVAL; CULTURE MEDIUM; ENZYMOLOGY; EPITHELIUM; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; NUTRITION; PATHOLOGY; TUMOR CELL LINE;

BREAST; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL LINEAGE; CELL PROLIFERATION; CELL SURVIVAL; COCULTURE TECHNIQUES; CULTURE MEDIA; EPITHELIUM; FEMALE; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTAMATE-AMMONIA LIGASE; GLUTAMINASE; GLUTAMINE; HUMANS; MOLECULAR TARGETED THERAPY; NUTRITION PROCESSES; PHENOTYPE; PROMOTER REGIONS, GENETIC;

EID: 80052338863     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002229     Document Type: Article

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