-
1
-
-
0027414085
-
Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype
-
Wadhwa, R.; Kaul, S.C.; Ikawa, Y.; Sugimoto, Y. Identification of a novel member of mouse hsp70 family. Its association with cellular mortal phenotype. J. Biol. Chem. 1993, 268, 6615-6621.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 6615-6621
-
-
Wadhwa, R.1
Kaul, S.C.2
Ikawa, Y.3
Sugimoto, Y.4
-
2
-
-
0028926541
-
Cloning and subcellular localization of human mitochondrial hsp70
-
Bhattacharyya, T.; Karnezis, A.N.; Murphy, S.P.; Hoang, T.; Freeman, B.C.; Phillips, B.; Morimoto, R.I. Cloning and subcellular localization of human mitochondrial hsp70. J. Biol. Chem. 1995, 270, 1705-1710.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 1705-1710
-
-
Bhattacharyya, T.1
Karnezis, A.N.2
Murphy, S.P.3
Hoang, T.4
Freeman, B.C.5
Phillips, B.6
Morimoto, R.I.7
-
3
-
-
0027263325
-
Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family
-
Domanico, S.Z.; DeNagel, D.C.; Dahlseid, J.N.; Green, J.M.; Pierce, S.K. Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family. Mol. Cell. Biol. 1993, 13, 3598-3610.
-
(1993)
Mol. Cell. Biol
, vol.13
, pp. 3598-3610
-
-
Domanico, S.Z.1
DeNagel, D.C.2
Dahlseid, J.N.3
Green, J.M.4
Pierce, S.K.5
-
4
-
-
0028596603
-
cDNA cloning and efficient mitochondrial import of pre-mtHSP70 from rat liver
-
Webster, T.J.; Naylor, D.J.; Hartman, D.J.; Hoj, P.B.; Hoogenraad, N.J. cDNA cloning and efficient mitochondrial import of pre-mtHSP70 from rat liver. DNA Cell Biol. 1994, 13, 1213-1220.
-
(1994)
DNA Cell Biol
, vol.13
, pp. 1213-1220
-
-
Webster, T.J.1
Naylor, D.J.2
Hartman, D.J.3
Hoj, P.B.4
Hoogenraad, N.J.5
-
5
-
-
33745475570
-
On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60
-
Deocaris, C.C.; Kaul, S.C.; Wadhwa, R. On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60. Cell Stress Chaperones 2006, 11, 116-128.
-
(2006)
Cell Stress Chaperones
, vol.11
, pp. 116-128
-
-
Deocaris, C.C.1
Kaul, S.C.2
Wadhwa, R.3
-
6
-
-
33751170698
-
Mitochondrial chaperones in cancer: From molecular biology to clinical diagnostics
-
Czarnecka, A.M.; Campanella, C.; Zummo, G.; Cappello, F. Mitochondrial chaperones in cancer: From molecular biology to clinical diagnostics. Cancer Biol. Ther. 2006, 5, 714-720.
-
(2006)
Cancer Biol. Ther
, vol.5
, pp. 714-720
-
-
Czarnecka, A.M.1
Campanella, C.2
Zummo, G.3
Cappello, F.4
-
7
-
-
11144349225
-
Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival
-
Dundas, S.R.; Lawrie, L.C.; Rooney, P.H.; Murray, G.I. Mortalin is over-expressed by colorectal adenocarcinomas and correlates with poor survival. J. Pathol. 2005, 205, 74-81.
-
(2005)
J. Pathol
, vol.205
, pp. 74-81
-
-
Dundas, S.R.1
Lawrie, L.C.2
Rooney, P.H.3
Murray, G.I.4
-
8
-
-
0028827813
-
The gene encoding PBP74/CSA/motalin-1, a novel mouse hsp70, maps to mouse chromosome 18
-
Ohashi, M.; Oyanagi, M.; Hatakeyama, K.; Inoue, M.; Kominami, R. The gene encoding PBP74/CSA/motalin-1, a novel mouse hsp70, maps to mouse chromosome 18. Genomics 1995, 30, 406-407.
-
(1995)
Genomics
, vol.30
, pp. 406-407
-
-
Ohashi, M.1
Oyanagi, M.2
Hatakeyama, K.3
Inoue, M.4
Kominami, R.5
-
9
-
-
27444442414
-
Identification and characterization of molecular interactions between mortalin/mthsp70 and hsp60
-
Wadhwa, R.; Takano, S.; Kaur, K.; Aida, S.; Yaguchi, T.; Kaul, Z.; Hirano, T.; Taira, K.; Kaul, S.C. Identification and characterization of molecular interactions between mortalin/mthsp70 and hsp60. Biochem. J. 2005, 391, 185-190.
-
(2005)
Biochem. J
, vol.391
, pp. 185-190
-
-
Wadhwa, R.1
Takano, S.2
Kaur, K.3
Aida, S.4
Yaguchi, T.5
Kaul, Z.6
Hirano, T.7
Taira, K.8
Kaul, S.C.9
-
10
-
-
0034522728
-
Human mortalin (HSPA9): A candidate for the myeloid leukemia tumor suppressor gene on 5q31
-
Xie, H.; Hu, Z.; Chyna, B.; Horrigan, S.K.; Westbrook, C.A. Human mortalin (HSPA9): A candidate for the myeloid leukemia tumor suppressor gene on 5q31. Leukemia 2000, 14, 2128-2134.
-
(2000)
Leukemia
, vol.14
, pp. 2128-2134
-
-
Xie, H.1
Hu, Z.2
Chyna, B.3
Horrigan, S.K.4
Westbrook, C.A.5
-
11
-
-
67649306594
-
The versatile stress protein mortalin as a chaperone therapeutic agent
-
Deocaris, C.C.; Kaul, S.C.; Wadhwa, R. The versatile stress protein mortalin as a chaperone therapeutic agent. Protein Pept. Lett. 2009, 16, 517-529.
-
(2009)
Protein Pept. Lett
, vol.16
, pp. 517-529
-
-
Deocaris, C.C.1
Kaul, S.C.2
Wadhwa, R.3
-
12
-
-
0036666032
-
An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: What, when, and where?
-
Wadhwa, R.; Taira, K.; Kaul, S.C. An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: What, when, and where? Cell Stress Chaperones 2002, 7, 309-316.
-
(2002)
Cell Stress Chaperones
, vol.7
, pp. 309-316
-
-
Wadhwa, R.1
Taira, K.2
Kaul, S.C.3
-
13
-
-
34447528828
-
The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions
-
Daugaard, M.; Rohde, M.; Jaattela, M. The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions. FEBS Lett. 2007, 581, 3702-3710.
-
(2007)
FEBS Lett
, vol.581
, pp. 3702-3710
-
-
Daugaard, M.1
Rohde, M.2
Jaattela, M.3
-
14
-
-
84858955705
-
Reactivation of protein aggregates by mortalin and Tid1-the human mitochondrial Hsp70 chaperone system
-
Iosefson, O.; Sharon, S.; Goloubinoff, P.; Azem, A. Reactivation of protein aggregates by mortalin and Tid1-the human mitochondrial Hsp70 chaperone system. Cell Stress Chaperones 2012, 17, 57-66.
-
(2012)
Cell Stress Chaperones
, vol.17
, pp. 57-66
-
-
Iosefson, O.1
Sharon, S.2
Goloubinoff, P.3
Azem, A.4
-
15
-
-
79959374989
-
Mitochondrial dysfunction induced by knockdown of mortalin is rescued by Parkin
-
Yang, H.; Zhou, X.; Liu, X.; Yang, L.; Chen, Q.; Zhao, D.; Zuo, J.; Liu, W. Mitochondrial dysfunction induced by knockdown of mortalin is rescued by Parkin. Biochem. Biophys. Res. Commun. 2011, 410, 114-120.
-
(2011)
Biochem. Biophys. Res. Commun
, vol.410
, pp. 114-120
-
-
Yang, H.1
Zhou, X.2
Liu, X.3
Yang, L.4
Chen, Q.5
Zhao, D.6
Zuo, J.7
Liu, W.8
-
16
-
-
0037051942
-
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75
-
Yokoyama, K.; Fukumoto, K.; Murakami, T.; Harada, S.; Hosono, R.; Wadhwa, R.; Mitsui, Y.; Ohkuma, S. Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75. FEBS Lett. 2002, 516, 53-57.
-
(2002)
FEBS Lett
, vol.516
, pp. 53-57
-
-
Yokoyama, K.1
Fukumoto, K.2
Murakami, T.3
Harada, S.4
Hosono, R.5
Wadhwa, R.6
Mitsui, Y.7
Ohkuma, S.8
-
17
-
-
0034682972
-
Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75
-
Ran, Q.; Wadhwa, R.; Kawai, R.; Kaul, S.C.; Sifers, R.N.; Bick, R.J.; Smith, J.R.; Pereira-Smith, O.M. Extramitochondrial localization of mortalin/mthsp70/PBP74/GRP75. Biochem. Biophys. Res. Commun. 2000, 275, 174-179.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.275
, pp. 174-179
-
-
Ran, Q.1
Wadhwa, R.2
Kawai, R.3
Kaul, S.C.4
Sifers, R.N.5
Bick, R.J.6
Smith, J.R.7
Pereira-Smith, O.M.8
-
18
-
-
0042091934
-
Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes
-
Wadhwa, R.; Ando, H.; Kawasaki, H.; Taira, K.; Kaul, S.C. Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes. EMBO Rep. 2003, 4, 595-601.
-
(2003)
EMBO Rep
, vol.4
, pp. 595-601
-
-
Wadhwa, R.1
Ando, H.2
Kawasaki, H.3
Taira, K.4
Kaul, S.C.5
-
19
-
-
56049114860
-
From proliferative to neurological role of an hsp70 stress chaperone, mortalin
-
Deocaris, C.C.; Kaul, S.C.; Wadhwa, R. From proliferative to neurological role of an hsp70 stress chaperone, mortalin. Biogerontology 2008, 9, 391-403.
-
(2008)
Biogerontology
, vol.9
, pp. 391-403
-
-
Deocaris, C.C.1
Kaul, S.C.2
Wadhwa, R.3
-
20
-
-
35148859811
-
Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice
-
Osorio, C.; Sullivan, P.M.; He, D.N.; Mace, B.E.; Ervin, J.F.; Strittmatter, W.J.; Alzate, O. Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice. Neurobiol. Aging 2007, 28, 1853-1862.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 1853-1862
-
-
Osorio, C.1
Sullivan, P.M.2
He, D.N.3
Mace, B.E.4
Ervin, J.F.5
Strittmatter, W.J.6
Alzate, O.7
-
21
-
-
79953674524
-
Simultaneous detection of changes in protein expression and oxidative modification as a function of age and APOE genotype
-
DeKroon, R.M.; Osorio, C.; Robinette, J.B.; Mocanu, M.; Winnik, W.M.; Alzate, O. Simultaneous detection of changes in protein expression and oxidative modification as a function of age and APOE genotype. J. Proteome Res. 2011, 10, 1632-1644.
-
(2011)
J. Proteome Res
, vol.10
, pp. 1632-1644
-
-
DeKroon, R.M.1
Osorio, C.2
Robinette, J.B.3
Mocanu, M.4
Winnik, W.M.5
Alzate, O.6
-
22
-
-
79955574923
-
-
Schrödinger, Version 1.2r3pre LLC. Available online, (accessed on 30 October 2011)
-
The PyMOL Molecular Graphics System, Version 1.2r3pre, Schrödinger, LLC. Available online: http://www.pymol.org/(accessed on 30 October 2011).
-
The PyMOL Molecular Graphics System
-
-
-
23
-
-
77950370585
-
Reconstitution of the mitochondrial Hsp70 (mortalin)-p53 interaction using purified proteins-Identification of additional interacting regions
-
Iosefson, O.; Azem, A. Reconstitution of the mitochondrial Hsp70 (mortalin)-p53 interaction using purified proteins-Identification of additional interacting regions. FEBS Lett. 2010, 584, 1080-1084.
-
(2010)
FEBS Lett
, vol.584
, pp. 1080-1084
-
-
Iosefson, O.1
Azem, A.2
-
24
-
-
14244268253
-
Effect of GRP75/mthsp70/PBP74/mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells
-
Liu, Y.; Liu, W.; Song, X.D.; Zuo, J. Effect of GRP75/mthsp70/PBP74/mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells. Mol. Cell. Biochem. 2005, 268, 45-51.
-
(2005)
Mol. Cell. Biochem
, vol.268
, pp. 45-51
-
-
Liu, Y.1
Liu, W.2
Song, X.D.3
Zuo, J.4
-
25
-
-
0030662415
-
Induction of novel Grp75 isoforms by 2-deoxyglucose in human and murine fibroblasts
-
Merrick, B.A.; Walker, V.R.; He, C.; Patterson, R.M.; Selkirk, J.K. Induction of novel Grp75 isoforms by 2-deoxyglucose in human and murine fibroblasts. Cancer Lett. 1997, 119, 185-190.
-
(1997)
Cancer Lett
, vol.119
, pp. 185-190
-
-
Merrick, B.A.1
Walker, V.R.2
He, C.3
Patterson, R.M.4
Selkirk, J.K.5
-
26
-
-
0021945545
-
Calcium ionophore A23187 induces expression of glucose-regulated genes and their heterologous fusion genes
-
Resendez, E., Jr.; Attenello, J.W.; Grafsky, A.; Chang, C.S.; Lee, A.S. Calcium ionophore A23187 induces expression of glucose-regulated genes and their heterologous fusion genes. Mol. Cell. Biol. 1985, 5, 1212-1219.
-
(1985)
Mol. Cell. Biol
, vol.5
, pp. 1212-1219
-
-
Resendez Jr., E.1
Attenello, J.W.2
Grafsky, A.3
Chang, C.S.4
Lee, A.S.5
-
27
-
-
0032444931
-
Thyroid hormone modifies mitochondrial phenotype by increasing protein import without altering degradation
-
Craig, E.E.; Chesley, A.; Hood, D.A. Thyroid hormone modifies mitochondrial phenotype by increasing protein import without altering degradation. Am. J. Physiol. 1998, 275, C1508-C1515.
-
(1998)
Am. J. Physiol
, vol.275
-
-
Craig, E.E.1
Chesley, A.2
Hood, D.A.3
-
28
-
-
0031443856
-
Induction of PBP74/mortalin/Grp75, a member of the hsp70 family, by low doses of ionizing radiation: A possible role in induced radioresistance
-
Sadekova, S.; Lehnert, S.; Chow, T.Y. Induction of PBP74/mortalin/Grp75, a member of the hsp70 family, by low doses of ionizing radiation: A possible role in induced radioresistance. Int. J. Radiat. Biol. 1997, 72, 653-660.
-
(1997)
Int. J. Radiat. Biol
, vol.72
, pp. 653-660
-
-
Sadekova, S.1
Lehnert, S.2
Chow, T.Y.3
-
29
-
-
0034595925
-
Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2
-
Kaul, S.C.; Reddel, R.R.; Sugihara, T.; Mitsui, Y.; Wadhwa, R. Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2. FEBS Lett. 2000, 474, 159-164.
-
(2000)
FEBS Lett
, vol.474
, pp. 159-164
-
-
Kaul, S.C.1
Reddel, R.R.2
Sugihara, T.3
Mitsui, Y.4
Wadhwa, R.5
-
30
-
-
78651071860
-
Mortalin overexpression attenuates betaamyloid-induced neurotoxicity in SH-SY5Y cells
-
Qu, M.; Zhou, Z.; Xu, S.; Chen, C.; Yu, Z.; Wang, D. Mortalin overexpression attenuates betaamyloid-induced neurotoxicity in SH-SY5Y cells. Brain Res. 2011, 1368, 336-345.
-
(2011)
Brain Res
, vol.1368
, pp. 336-345
-
-
Qu, M.1
Zhou, Z.2
Xu, S.3
Chen, C.4
Yu, Z.5
Wang, D.6
-
31
-
-
59149091608
-
Overexpression of mitochondrial Hsp70/Hsp75 in rat brain protects mitochondria, reduces oxidative stress, and protects from focal ischemia
-
Xu, L.; Voloboueva, L.A.; Ouyang, Y.; Emery, J.F.; Giffard, R.G. Overexpression of mitochondrial Hsp70/Hsp75 in rat brain protects mitochondria, reduces oxidative stress, and protects from focal ischemia. J. Cereb. Blood Flow Metab. 2009, 29, 365-374.
-
(2009)
J. Cereb. Blood Flow Metab
, vol.29
, pp. 365-374
-
-
Xu, L.1
Voloboueva, L.A.2
Ouyang, Y.3
Emery, J.F.4
Giffard, R.G.5
-
32
-
-
0037112550
-
Proteome analysis and functional expression identify mortalin as an antiapoptotic gene induced by elevation of [Na+]i/[K+]i ratio in cultured vascular smooth muscle cells
-
Taurin, S.; Seyrantepe, V.; Orlov, S.N.; Tremblay, T.L.; Thibault, P.; Bennett, M.R.; Hamet, P.; Pshezhetsky, A.V. Proteome analysis and functional expression identify mortalin as an antiapoptotic gene induced by elevation of [Na+]i/[K+]i ratio in cultured vascular smooth muscle cells. Circ. Res. 2002, 91, 915-922.
-
(2002)
Circ. Res
, vol.91
, pp. 915-922
-
-
Taurin, S.1
Seyrantepe, V.2
Orlov, S.N.3
Tremblay, T.L.4
Thibault, P.5
Bennett, M.R.6
Hamet, P.7
Pshezhetsky, A.V.8
-
33
-
-
0037447901
-
Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts
-
Kaul, S.C.; Yaguchi, T.; Taira, K.; Reddel, R.R.; Wadhwa, R. Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts. Exp. Cell Res. 2003, 286, 96-101.
-
(2003)
Exp. Cell Res
, vol.286
, pp. 96-101
-
-
Kaul, S.C.1
Yaguchi, T.2
Taira, K.3
Reddel, R.R.4
Wadhwa, R.5
-
34
-
-
33847651284
-
Three faces of mortalin: A housekeeper, guardian and killer
-
Kaul, S.C.; Deocaris, C.C.; Wadhwa, R. Three faces of mortalin: A housekeeper, guardian and killer. Exp. Gerontol. 2007, 42, 263-274.
-
(2007)
Exp. Gerontol
, vol.42
, pp. 263-274
-
-
Kaul, S.C.1
Deocaris, C.C.2
Wadhwa, R.3
-
35
-
-
0033569655
-
Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin
-
Mizukoshi, E.; Suzuki, M.; Loupatov, A.; Uruno, T.; Hayashi, H.; Misono, T.; Kaul, S.C.; Wadhwa, R.; Imamura, T. Fibroblast growth factor-1 interacts with the glucose-regulated protein GRP75/mortalin. Biochem. J. 1999, 343, 461-466.
-
(1999)
Biochem. J
, vol.343
, pp. 461-466
-
-
Mizukoshi, E.1
Suzuki, M.2
Loupatov, A.3
Uruno, T.4
Hayashi, H.5
Misono, T.6
Kaul, S.C.7
Wadhwa, R.8
Imamura, T.9
-
36
-
-
0032942448
-
ATP-sensitive association of mortalin with the IL-1 receptor type I
-
Sacht, G.; Brigelius-Flohe, R.; Kiess, M.; Sztajer, H.; Flohe, L. ATP-sensitive association of mortalin with the IL-1 receptor type I. Biofactors 1999, 9, 49-60.
-
(1999)
Biofactors
, vol.9
, pp. 49-60
-
-
Sacht, G.1
Brigelius-Flohe, R.2
Kiess, M.3
Sztajer, H.4
Flohe, L.5
-
37
-
-
24144457748
-
Mortalin/GRP75 promotes release of membrane vesicles from immune attacked cells and protection from complement-mediated lysis
-
Pilzer, D.; Fishelson, Z. Mortalin/GRP75 promotes release of membrane vesicles from immune attacked cells and protection from complement-mediated lysis. Int. Immunol. 2005, 17, 1239-1248.
-
(2005)
Int. Immunol
, vol.17
, pp. 1239-1248
-
-
Pilzer, D.1
Fishelson, Z.2
-
38
-
-
0036186681
-
Implication of PBP74/mortalin/GRP75 in the radio-adaptive response
-
Carette, J.; Lehnert, S.; Chow, T.Y. Implication of PBP74/mortalin/GRP75 in the radio-adaptive response. Int. J. Radiat. Biol. 2002, 78, 183-190.
-
(2002)
Int. J. Radiat. Biol
, vol.78
, pp. 183-190
-
-
Carette, J.1
Lehnert, S.2
Chow, T.Y.3
-
39
-
-
0029937415
-
Immunostaining of mitochondrial heat shock proteins (mtHSPs) in skeletal muscle fibers of mitochondrial cytopathy
-
Ibi, T.; Sahashi, K.; Ling, J.; Marui, K.; Mitsuma, T. Immunostaining of mitochondrial heat shock proteins (mtHSPs) in skeletal muscle fibers of mitochondrial cytopathy. Rinsho Shinkeigaku 1996, 36, 61-64.
-
(1996)
Rinsho Shinkeigaku
, vol.36
, pp. 61-64
-
-
Ibi, T.1
Sahashi, K.2
Ling, J.3
Marui, K.4
Mitsuma, T.5
-
40
-
-
0037203958
-
Asymmetric segregation of mitochondria and mortalin correlates with the multi-lineage potential of inner ear sensory cell progenitors in vitro
-
Rivolta, M.N.; Holley, M.C. Asymmetric segregation of mitochondria and mortalin correlates with the multi-lineage potential of inner ear sensory cell progenitors in vitro. Brain Res. Dev. Brain Res. 2002, 133, 49-56.
-
(2002)
Brain Res. Dev. Brain Res
, vol.133
, pp. 49-56
-
-
Rivolta, M.N.1
Holley, M.C.2
-
41
-
-
0036815606
-
Mortalin: Present and prospective
-
Kaul, S.C.; Taira, K.; Pereira-Smith, O.M.; Wadhwa, R. Mortalin: Present and prospective. Exp. Gerontol. 2002, 37, 1157-1164.
-
(2002)
Exp. Gerontol
, vol.37
, pp. 1157-1164
-
-
Kaul, S.C.1
Taira, K.2
Pereira-Smith, O.M.3
Wadhwa, R.4
-
42
-
-
0036346345
-
Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein
-
Wadhwa, R.; Yaguchi, T.; Hasan, M.K.; Mitsui, Y.; Reddel, R.R.; Kaul, S.C. Hsp70 family member, mot-2/mthsp70/GRP75, binds to the cytoplasmic sequestration domain of the p53 protein. Exp. Cell Res. 2002, 274, 246-253.
-
(2002)
Exp. Cell Res
, vol.274
, pp. 246-253
-
-
Wadhwa, R.1
Yaguchi, T.2
Hasan, M.K.3
Mitsui, Y.4
Reddel, R.R.5
Kaul, S.C.6
-
43
-
-
11844251260
-
Regulation of gene expression by the amyloid precursor protein: Inhibition of the JNK/c-Jun pathway
-
Kogel, D.; Schomburg, R.; Copanaki, E.; Prehn, J.H. Regulation of gene expression by the amyloid precursor protein: Inhibition of the JNK/c-Jun pathway. Cell Death Differ. 2005, 12, 1-9.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1-9
-
-
Kogel, D.1
Schomburg, R.2
Copanaki, E.3
Prehn, J.H.4
-
44
-
-
28044449126
-
Death-signal-induced relocalization of cyclin-dependent kinase 11 to mitochondria
-
Feng, Y.; Ariza, M.E.; Goulet, A.C.; Shi, J.; Nelson, M.A. Death-signal-induced relocalization of cyclin-dependent kinase 11 to mitochondria. Biochem. J. 2005, 392, 65-73.
-
(2005)
Biochem. J
, vol.392
, pp. 65-73
-
-
Feng, Y.1
Ariza, M.E.2
Goulet, A.C.3
Shi, J.4
Nelson, M.A.5
-
45
-
-
77958479016
-
Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: Functional impact of disease-related variants on mitochondrial homeostasis
-
Burbulla, L.F.; Schelling, C.; Kato, H.; Rapaport, D.; Woitalla, D.; Schiesling, C.; Schulte, C.; Sharma, M.; Illig, T.; Bauer, P.; et al. Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: Functional impact of disease-related variants on mitochondrial homeostasis. Hum. Mol. Genet. 2010, 19, 4437-4452.
-
(2010)
Hum. Mol. Genet
, vol.19
, pp. 4437-4452
-
-
Burbulla, L.F.1
Schelling, C.2
Kato, H.3
Rapaport, D.4
Woitalla, D.5
Schiesling, C.6
Schulte, C.7
Sharma, M.8
Illig, T.9
Bauer, P.10
-
46
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Aviles, R.M.; Wilson, M.A.; Miller, D.W.; Ahmad, R.; McLendon, C.; Bandyopadhyay, S.; Baptista, M.J.; Ringe, D.; Petsko, G.A.; Cookson, M.R. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. USA 2004, 101, 9103-9108.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
47
-
-
33746296891
-
Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: Relevance to Parkinson disease
-
Jin, J.; Hulette, C.; Wang, Y.; Zhang, T.; Pan, C.; Wadhwa, R.; Zhang, J. Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: Relevance to Parkinson disease. Mol. Cell. Proteomics 2006, 5, 1193-1204.
-
(2006)
Mol. Cell. Proteomics
, vol.5
, pp. 1193-1204
-
-
Jin, J.1
Hulette, C.2
Wang, Y.3
Zhang, T.4
Pan, C.5
Wadhwa, R.6
Zhang, J.7
-
48
-
-
0034805507
-
Cell-cycle dependent tyrosine phosphorylation on mortalin regulates its interaction with fibroblast growth factor-1
-
Mizukoshi, E.; Suzuki, M.; Misono, T.; Loupatov, A.; Munekata, E.; Kaul, S.C.; Wadhwa, R.; Imamura, T. Cell-cycle dependent tyrosine phosphorylation on mortalin regulates its interaction with fibroblast growth factor-1. Biochem. Biophys. Res. Commun. 2001, 280, 1203-1209.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.280
, pp. 1203-1209
-
-
Mizukoshi, E.1
Suzuki, M.2
Misono, T.3
Loupatov, A.4
Munekata, E.5
Kaul, S.C.6
Wadhwa, R.7
Imamura, T.8
-
49
-
-
0035879050
-
Identification and characterization of molecular interactions between glucose-regulated proteins (GRPs) mortalin/GRP75/peptide-binding protein 74 (PBP74) and GRP94
-
Takano, S.; Wadhwa, R.; Mitsui, Y.; Kaul, S.C. Identification and characterization of molecular interactions between glucose-regulated proteins (GRPs) mortalin/GRP75/peptide-binding protein 74 (PBP74) and GRP94. Biochem. J. 2001, 357, 393-398.
-
(2001)
Biochem. J
, vol.357
, pp. 393-398
-
-
Takano, S.1
Wadhwa, R.2
Mitsui, Y.3
Kaul, S.C.4
-
50
-
-
28844448157
-
Glucose regulated proteins 78 and 75 bind to the receptor for hyaluronan mediated motility in interphase microtubules
-
Kuwabara, H.; Yoneda, M.; Hayasaki, H.; Nakamura, T.; Mori, H. Glucose regulated proteins 78 and 75 bind to the receptor for hyaluronan mediated motility in interphase microtubules. Biochem. Biophys. Res. Commun. 2006, 339, 971-976.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.339
, pp. 971-976
-
-
Kuwabara, H.1
Yoneda, M.2
Hayasaki, H.3
Nakamura, T.4
Mori, H.5
-
51
-
-
0037459206
-
Mortalin-MPD (mevalonate pyrophosphate decarboxylase) interactions and their role in control of cellular proliferation
-
Wadhwa, R.; Yaguchi, T.; Hasan, M.K.; Taira, K.; Kaul, S.C. Mortalin-MPD (mevalonate pyrophosphate decarboxylase) interactions and their role in control of cellular proliferation. Biochem. Biophys. Res. Commun. 2003, 302, 735-742.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.302
, pp. 735-742
-
-
Wadhwa, R.1
Yaguchi, T.2
Hasan, M.K.3
Taira, K.4
Kaul, S.C.5
-
52
-
-
0032491426
-
Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member
-
Wadhwa, R.; Takano, S.; Robert, M.; Yoshida, A.; Nomura, H.; Reddel, R.R.; Mitsui, Y.; Kaul, S.C. Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member. J. Biol. Chem. 1998, 273, 29586-29591.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 29586-29591
-
-
Wadhwa, R.1
Takano, S.2
Robert, M.3
Yoshida, A.4
Nomura, H.5
Reddel, R.R.6
Mitsui, Y.7
Kaul, S.C.8
-
53
-
-
2942584910
-
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential
-
Orsini, F.; Migliaccio, E.; Moroni, M.; Contursi, C.; Raker, V.A.; Piccini, D.; Martin-Padura, I.; Pelliccia, G.; Trinei, M.; Bono, M.; et al. The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential. J. Biol. Chem. 2004, 279, 25689-25695.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 25689-25695
-
-
Orsini, F.1
Migliaccio, E.2
Moroni, M.3
Contursi, C.4
Raker, V.A.5
Piccini, D.6
Martin-Padura, I.7
Pelliccia, G.8
Trinei, M.9
Bono, M.10
-
54
-
-
17644391695
-
p66SHC: The apoptotic side of Shc proteins
-
Pellegrini, M.; Pacini, S.; Baldari, C.T. p66SHC: The apoptotic side of Shc proteins. Apoptosis 2005, 10, 13-18.
-
(2005)
Apoptosis
, vol.10
, pp. 13-18
-
-
Pellegrini, M.1
Pacini, S.2
Baldari, C.T.3
-
55
-
-
77958535699
-
Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts
-
doi:10.1371/journal.pone.0012962
-
Grunewald, A.; Voges, L.; Rakovic, A.; Kasten, M.; Vandebona, H.; Hemmelmann, C.; Lohmann, K.; Orolicki, S.; Ramirez, A.; Schapira, A.H.; et al. Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts. PLoS One 2010, 5, doi:10.1371/journal.pone.0012962.
-
(2010)
PLoS One
, vol.5
-
-
Grunewald, A.1
Voges, L.2
Rakovic, A.3
Kasten, M.4
Vandebona, H.5
Hemmelmann, C.6
Lohmann, K.7
Orolicki, S.8
Ramirez, A.9
Schapira, A.H.10
-
56
-
-
77953529863
-
Understanding the functional interplay between mammalian mitochondrial Hsp70 chaperone machine components
-
Goswami, A.V.; Chittoor, B.; D'Silva, P. Understanding the functional interplay between mammalian mitochondrial Hsp70 chaperone machine components. J. Biol. Chem. 2010, 285, 19472-19482.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 19472-19482
-
-
Goswami, A.V.1
Chittoor, B.2
D'Silva, P.3
-
57
-
-
42549112997
-
Overexpression of mitochondrial Hsp70/Hsp75 protects astrocytes against ischemic injury in vitro
-
Voloboueva, L.A.; Duan, M.; Ouyang, Y.; Emery, J.F.; Stoy, C.; Giffard, R.G. Overexpression of mitochondrial Hsp70/Hsp75 protects astrocytes against ischemic injury in vitro. J. Cereb. Blood Flow Metab. 2008, 28, 1009-1016.
-
(2008)
J. Cereb. Blood Flow Metab
, vol.28
, pp. 1009-1016
-
-
Voloboueva, L.A.1
Duan, M.2
Ouyang, Y.3
Emery, J.F.4
Stoy, C.5
Giffard, R.G.6
-
58
-
-
0036257364
-
Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74
-
Schwarzer, C.; Barnikol-Watanabe, S.; Thinnes, F.P.; Hilschmann, N. Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74. Int. J. Biochem. Cell Biol. 2002, 34, 1059-1070.
-
(2002)
Int. J. Biochem. Cell Biol
, vol.34
, pp. 1059-1070
-
-
Schwarzer, C.1
Barnikol-Watanabe, S.2
Thinnes, F.P.3
Hilschmann, N.4
-
59
-
-
83155181415
-
Inhibition of mitochondrial permeability transition pore opening is involved in the protective effects of mortalin overexpression against beta-amyloid-induced apoptosis in SH-SY5Y cells
-
Qu, M.; Zhou, Z.; Chen, C.; Li, M.; Pei, L.; Yang, J.; Wang, Y.; Li, L.; Liu, C.; Zhang, G.; et al. Inhibition of mitochondrial permeability transition pore opening is involved in the protective effects of mortalin overexpression against beta-amyloid-induced apoptosis in SH-SY5Y cells. Neurosci. Res. 2012, 72, 94-102.
-
(2012)
Neurosci. Res
, vol.72
, pp. 94-102
-
-
Qu, M.1
Zhou, Z.2
Chen, C.3
Li, M.4
Pei, L.5
Yang, J.6
Wang, Y.7
Li, L.8
Liu, C.9
Zhang, G.10
-
60
-
-
0029157324
-
Expression of stress proteins and mitochondrial chaperonins in chronically stimulated skeletal muscle
-
Ornatsky, O.I.; Connor, M.K.; Hood, D.A. Expression of stress proteins and mitochondrial chaperonins in chronically stimulated skeletal muscle. Biochem. J. 1995, 311, 119-123.
-
(1995)
Biochem. J
, vol.311
, pp. 119-123
-
-
Ornatsky, O.I.1
Connor, M.K.2
Hood, D.A.3
-
61
-
-
0031831491
-
Contractile activity-induced adaptations in the mitochondrial protein import system
-
Takahashi, M.; Chesley, A.; Freyssenet, D.; Hood, D.A. Contractile activity-induced adaptations in the mitochondrial protein import system. Am. J. Physiol. 1998, 274, C1380-C1387.
-
(1998)
Am. J. Physiol
, vol.274
-
-
Takahashi, M.1
Chesley, A.2
Freyssenet, D.3
Hood, D.A.4
-
62
-
-
0029550894
-
Dissection of protein translocation across the mitochondrial outer and inner membranes
-
Brunner, M.; Schneider, H.C.; Lill, R.; Neupert, W. Dissection of protein translocation across the mitochondrial outer and inner membranes. Cold Spring Harb. Symp. Quant. Biol. 1995, 60, 619-627.
-
(1995)
Cold Spring Harb. Symp. Quant. Biol
, vol.60
, pp. 619-627
-
-
Brunner, M.1
Schneider, H.C.2
Lill, R.3
Neupert, W.4
-
63
-
-
0028132179
-
Mitochondrial Hsp70/MIM44 complex facilitates protein import
-
Schneider, H.C.; Berthold, J.; Bauer, M.F.; Dietmeier, K.; Guiard, B.; Brunner, M.; Neupert, W. Mitochondrial Hsp70/MIM44 complex facilitates protein import. Nature 1994, 371, 768-774.
-
(1994)
Nature
, vol.371
, pp. 768-774
-
-
Schneider, H.C.1
Berthold, J.2
Bauer, M.F.3
Dietmeier, K.4
Guiard, B.5
Brunner, M.6
Neupert, W.7
-
64
-
-
71749108967
-
Mitochondrial protein homeostasis: The cooperative roles of chaperones and proteases
-
Voos, W. Mitochondrial protein homeostasis: The cooperative roles of chaperones and proteases. Res. Microbiol. 2009, 160, 718-725.
-
(2009)
Res. Microbiol
, vol.160
, pp. 718-725
-
-
Voos, W.1
-
65
-
-
0032760629
-
Mechanisms of protein translocation into mitochondria
-
Voos, W.; Martin, H.; Krimmer, T.; Pfanner, N. Mechanisms of protein translocation into mitochondria. Biochim. Biophys. Acta 1999, 1422, 235-254.
-
(1999)
Biochim. Biophys. Acta
, vol.1422
, pp. 235-254
-
-
Voos, W.1
Martin, H.2
Krimmer, T.3
Pfanner, N.4
-
66
-
-
80155192450
-
Lateral release of proteins from the TOM complex into the outer membrane of mitochondria
-
Harner, M.; Neupert, W.; Deponte, M. Lateral release of proteins from the TOM complex into the outer membrane of mitochondria. EMBO J. 2011, 30, 3232-3241.
-
(2011)
EMBO J
, vol.30
, pp. 3232-3241
-
-
Harner, M.1
Neupert, W.2
Deponte, M.3
-
67
-
-
0037009130
-
Molecular chaperones as essential mediators of mitochondrial biogenesis
-
Voos, W.; Rottgers, K. Molecular chaperones as essential mediators of mitochondrial biogenesis. Biochim. Biophys. Acta 2002, 1592, 51-62.
-
(2002)
Biochim. Biophys. Acta
, vol.1592
, pp. 51-62
-
-
Voos, W.1
Rottgers, K.2
-
68
-
-
0035282966
-
The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation
-
Lim, J.H.; Martin, F.; Guiard, B.; Pfanner, N.; Voos, W. The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation. EMBO J. 2001, 20, 941-950.
-
(2001)
EMBO J
, vol.20
, pp. 941-950
-
-
Lim, J.H.1
Martin, F.2
Guiard, B.3
Pfanner, N.4
Voos, W.5
-
69
-
-
79851514913
-
Understanding the molecular mechanism of protein translocation across the mitochondrial inner membrane: Still a long way to go
-
Marom, M.; Azem, A.; Mokranjac, D. Understanding the molecular mechanism of protein translocation across the mitochondrial inner membrane: Still a long way to go. Biochim. Biophys. Acta 2011, 1808, 990-1001.
-
(2011)
Biochim. Biophys. Acta
, vol.1808
, pp. 990-1001
-
-
Marom, M.1
Azem, A.2
Mokranjac, D.3
-
71
-
-
0027049693
-
Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane
-
Scherer, P.E.; Manning-Krieg, U.C.; Jeno, P.; Schatz, G.; Horst, M. Identification of a 45-kDa protein at the protein import site of the yeast mitochondrial inner membrane. Proc. Natl. Acad. Sci. USA 1992, 89, 11930-11934.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 11930-11934
-
-
Scherer, P.E.1
Manning-Krieg, U.C.2
Jeno, P.3
Schatz, G.4
Horst, M.5
-
72
-
-
7544224771
-
Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane
-
D'Silva, P.; Liu, Q.; Walter, W.; Craig, E.A. Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane. Nat. Struct. Mol. Biol. 2004, 11, 1084-1091.
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 1084-1091
-
-
D'Silva, P.1
Liu, Q.2
Walter, W.3
Craig, E.A.4
-
73
-
-
67049108831
-
The mitochondrial protein translocation motor: Structural conservation between the human and yeast Tim14/Pam18-Tim16/Pam16 co-chaperones
-
Elsner, S.; Simian, D.; Iosefson, O.; Marom, M.; Azem, A. The mitochondrial protein translocation motor: Structural conservation between the human and yeast Tim14/Pam18-Tim16/Pam16 co-chaperones. Int. J. Mol. Sci. 2009, 10, 2041-2053.
-
(2009)
Int. J. Mol. Sci
, vol.10
, pp. 2041-2053
-
-
Elsner, S.1
Simian, D.2
Iosefson, O.3
Marom, M.4
Azem, A.5
-
74
-
-
0141865519
-
Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria
-
Mokranjac, D.; Sichting, M.; Neupert, W.; Hell, K. Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria. EMBO J. 2003, 22, 4945-4956.
-
(2003)
EMBO J
, vol.22
, pp. 4945-4956
-
-
Mokranjac, D.1
Sichting, M.2
Neupert, W.3
Hell, K.4
-
75
-
-
0033985183
-
Apoptosis and the nervous system
-
Sastry, P.S.; Rao, K.S. Apoptosis and the nervous system. J. Neurochem. 2000, 74, 1-20.
-
(2000)
J. Neurochem
, vol.74
, pp. 1-20
-
-
Sastry, P.S.1
Rao, K.S.2
-
76
-
-
84920065476
-
Redox Proteomics of Oxidatively Modified Brain Proteins in Mild Cognitive Impairment
-
In, Alzate, O., Ed.; CRC Press: Boca Raton, FL, USA
-
Reed, T.T.; Sultana, R.; Butterfield, D.A. Redox Proteomics of Oxidatively Modified Brain Proteins in Mild Cognitive Impairment. In Neuroproteomics; Alzate, O., Ed.; CRC Press: Boca Raton, FL, USA, 2010; volume 38, p. 322.
-
(2010)
Neuroproteomics
, vol.38
, pp. 322
-
-
Reed, T.T.1
Sultana, R.2
Butterfield, D.A.3
-
77
-
-
34247171756
-
Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans
-
Kimura, K.; Tanaka, N.; Nakamura, N.; Takano, S.; Ohkuma, S. Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans. J. Biol. Chem. 2007, 282, 5910-5918.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 5910-5918
-
-
Kimura, K.1
Tanaka, N.2
Nakamura, N.3
Takano, S.4
Ohkuma, S.5
-
78
-
-
41149152733
-
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
-
Chipuk, J.E.; Green, D.R. How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol. 2008, 18, 157-164.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 157-164
-
-
Chipuk, J.E.1
Green, D.R.2
-
79
-
-
0842281645
-
Cell death: Critical control points
-
Danial, N.N.; Korsmeyer, S.J. Cell death: Critical control points. Cell 2004, 116, 205-219.
-
(2004)
Cell
, vol.116
, pp. 205-219
-
-
Danial, N.N.1
Korsmeyer, S.J.2
-
80
-
-
84860389354
-
Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases
-
Strasser, A.; Cory, S.; Adams, J.M. Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases. EMBO J. 2011, 30, 3667-3683.
-
(2011)
EMBO J
, vol.30
, pp. 3667-3683
-
-
Strasser, A.1
Cory, S.2
Adams, J.M.3
-
81
-
-
0343341218
-
Staurosporine-induced neuronal death: Multiple mechanisms and methodological implications
-
Deshmukh, M.; Johnson, E.M., Jr. Staurosporine-induced neuronal death: Multiple mechanisms and methodological implications. Cell Death Differ. 2000, 7, 250-261.
-
(2000)
Cell Death Differ
, vol.7
, pp. 250-261
-
-
Deshmukh, M.1
Johnson Jr., E.M.2
-
82
-
-
81055125652
-
Programmed cell death in animal development and disease
-
Fuchs, Y.; Steller, H. Programmed cell death in animal development and disease. Cell 2011, 147, 742-758.
-
(2011)
Cell
, vol.147
, pp. 742-758
-
-
Fuchs, Y.1
Steller, H.2
-
83
-
-
0034569527
-
Executionary pathway for apoptosis: Lessons from mutant mice
-
Woo, M.; Hakem, R.; Mak, T.W. Executionary pathway for apoptosis: Lessons from mutant mice. Cell Res. 2000, 10, 267-278.
-
(2000)
Cell Res
, vol.10
, pp. 267-278
-
-
Woo, M.1
Hakem, R.2
Mak, T.W.3
-
84
-
-
77956908962
-
Regulation of the Apaf-1-caspase-9 apoptosome
-
Bratton, S.B.; Salvesen, G.S. Regulation of the Apaf-1-caspase-9 apoptosome. J. Cell Sci. 2010, 123, 3209-3214.
-
(2010)
J. Cell Sci
, vol.123
, pp. 3209-3214
-
-
Bratton, S.B.1
Salvesen, G.S.2
-
85
-
-
0033805296
-
Triggering and modulation of apoptosis by oxidative stress
-
Chandra, J.; Samali, A.; Orrenius, S. Triggering and modulation of apoptosis by oxidative stress. Free Radic. Biol. Med. 2000, 29, 323-333.
-
(2000)
Free Radic. Biol. Med
, vol.29
, pp. 323-333
-
-
Chandra, J.1
Samali, A.2
Orrenius, S.3
-
86
-
-
79551620159
-
Apoptosis and oncogenesis: Give and take in the BCL-2 family
-
Llambi, F.; Green, D.R. Apoptosis and oncogenesis: Give and take in the BCL-2 family. Curr. Opin. Genet. Dev. 2011, 21, 12-20.
-
(2011)
Curr. Opin. Genet. Dev
, vol.21
, pp. 12-20
-
-
Llambi, F.1
Green, D.R.2
-
87
-
-
81355146366
-
A unified model of mammalian BCL-2 protein family interactions at the mitochondria
-
Llambi, F.; Moldoveanu, T.; Tait, S.W.; Bouchier-Hayes, L.; Temirov, J.; McCormick, L.L.; Dillon, C.P.; Green, D.R. A unified model of mammalian BCL-2 protein family interactions at the mitochondria. Mol. Cell 2011, 44, 517-531.
-
(2011)
Mol. Cell
, vol.44
, pp. 517-531
-
-
Llambi, F.1
Moldoveanu, T.2
Tait, S.W.3
Bouchier-Hayes, L.4
Temirov, J.5
McCormick, L.L.6
Dillon, C.P.7
Green, D.R.8
-
88
-
-
17244368276
-
Structure of the apoptotic protease-activating factor 1 bound to ADP
-
Riedl, S.J.; Li, W.; Chao, Y.; Schwarzenbacher, R.; Shi, Y. Structure of the apoptotic protease-activating factor 1 bound to ADP. Nature 2005, 434, 926-933.
-
(2005)
Nature
, vol.434
, pp. 926-933
-
-
Riedl, S.J.1
Li, W.2
Chao, Y.3
Schwarzenbacher, R.4
Shi, Y.5
-
89
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou, H.; Henzel, W.J.; Liu, X.; Lutschg, A.; Wang, X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997, 90, 405-413.
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
90
-
-
0034253533
-
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
-
Beere, H.M.; Wolf, B.B.; Cain, K.; Mosser, D.D.; Mahboubi, A.; Kuwana, T.; Tailor, P.; Morimoto, R.I.; Cohen, G.M.; Green, D.R. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat. Cell Biol. 2000, 2, 469-475.
-
(2000)
Nat. Cell Biol
, vol.2
, pp. 469-475
-
-
Beere, H.M.1
Wolf, B.B.2
Cain, K.3
Mosser, D.D.4
Mahboubi, A.5
Kuwana, T.6
Tailor, P.7
Morimoto, R.I.8
Cohen, G.M.9
Green, D.R.10
-
91
-
-
0037022352
-
Cytochrome c release from mitochondria proceeds by a two-step process
-
Ott, M.; Robertson, J.D.; Gogvadze, V.; Zhivotovsky, B.; Orrenius, S. Cytochrome c release from mitochondria proceeds by a two-step process. Proc. Natl. Acad. Sci. USA 2002, 99, 1259-1263.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1259-1263
-
-
Ott, M.1
Robertson, J.D.2
Gogvadze, V.3
Zhivotovsky, B.4
Orrenius, S.5
-
92
-
-
79955827220
-
Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy
-
Lu, W.J.; Lee, N.P.; Kaul, S.C.; Lan, F.; Poon, R.T.; Wadhwa, R.; Luk, J.M. Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy. Cell Death Differ. 2011, 18, 1046-1056.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1046-1056
-
-
Lu, W.J.1
Lee, N.P.2
Kaul, S.C.3
Lan, F.4
Poon, R.T.5
Wadhwa, R.6
Luk, J.M.7
-
93
-
-
35448940572
-
Studies of apoptosis proteins in yeast
-
Zhang, H.; Reed, J.C. Studies of apoptosis proteins in yeast. Methods Cell Biol. 2001, 66, 453-468.
-
(2001)
Methods Cell Biol
, vol.66
, pp. 453-468
-
-
Zhang, H.1
Reed, J.C.2
-
94
-
-
33846297971
-
Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis
-
Liu, S.; Li, J.; Tao, Y.; Xiao, X. Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis. Biochem. Biophys. Res. Commun. 2007, 354, 109-114.
-
(2007)
Biochem. Biophys. Res. Commun
, vol.354
, pp. 109-114
-
-
Liu, S.1
Li, J.2
Tao, Y.3
Xiao, X.4
-
95
-
-
0037428078
-
Parc: A cytoplasmic anchor for p53
-
Nikolaev, A.Y.; Li, M.; Puskas, N.; Qin, J.; Gu, W. Parc: A cytoplasmic anchor for p53. Cell 2003, 112, 29-40.
-
(2003)
Cell
, vol.112
, pp. 29-40
-
-
Nikolaev, A.Y.1
Li, M.2
Puskas, N.3
Qin, J.4
Gu, W.5
-
96
-
-
0345167026
-
Sequestration of p53 in the cytoplasm by adenovirus type 12 E1B 55-kilodalton oncoprotein is required for inhibition of p53-mediated apoptosis
-
Zhao, L.Y.; Liao, D. Sequestration of p53 in the cytoplasm by adenovirus type 12 E1B 55-kilodalton oncoprotein is required for inhibition of p53-mediated apoptosis. J. Virol. 2003, 77, 13171-13181.
-
(2003)
J. Virol
, vol.77
, pp. 13171-13181
-
-
Zhao, L.Y.1
Liao, D.2
-
97
-
-
77953384831
-
Tumor suppressive functions of p53
-
doi:10.1101/cshperspect.a001883
-
Zilfou, J.T.; Lowe, S.W. Tumor suppressive functions of p53. Cold Spring Harb. Perspect. Biol. 2009, 1, doi:10.1101/cshperspect.a001883.
-
(2009)
Cold Spring Harb. Perspect. Biol
, vol.1
-
-
Zilfou, J.T.1
Lowe, S.W.2
-
98
-
-
36549077003
-
Functional significance of minor structural and expression changes in stress chaperone mortalin
-
Deocaris, C.C.; Widodo, N.; Ishii, T.; Kaul, S.C.; Wadhwa, R. Functional significance of minor structural and expression changes in stress chaperone mortalin. Ann. N. Y. Acad. Sci. 2007, 1119, 165-175.
-
(2007)
Ann. N.Y. Acad. Sci
, vol.1119
, pp. 165-175
-
-
Deocaris, C.C.1
Widodo, N.2
Ishii, T.3
Kaul, S.C.4
Wadhwa, R.5
-
99
-
-
28244470279
-
Activation of wild type p53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides
-
Kaul, S.C.; Aida, S.; Yaguchi, T.; Kaur, K.; Wadhwa, R. Activation of wild type p53 function by its mortalin-binding, cytoplasmically localizing carboxyl terminus peptides. J. Biol. Chem. 2005, 280, 39373-39379.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 39373-39379
-
-
Kaul, S.C.1
Aida, S.2
Yaguchi, T.3
Kaur, K.4
Wadhwa, R.5
-
100
-
-
41149105243
-
ROS and p53: A versatile partnership
-
Liu, B.; Chen, Y.; St Clair, D.K. ROS and p53: A versatile partnership. Free Radic. Biol. Med. 2008, 44, 1529-1535.
-
(2008)
Free Radic. Biol. Med
, vol.44
, pp. 1529-1535
-
-
Liu, B.1
Chen, Y.2
St Clair, D.K.3
-
101
-
-
0036883535
-
Chaperones and aging: Role in neurodegeneration and in other civilizational diseases
-
Soti, C.; Csermely, P. Chaperones and aging: Role in neurodegeneration and in other civilizational diseases. Neurochem. Int. 2002, 41, 383-389.
-
(2002)
Neurochem. Int
, vol.41
, pp. 383-389
-
-
Soti, C.1
Csermely, P.2
-
102
-
-
0030841350
-
Protein oxidation in aging, disease, and oxidative stress
-
Berlett, B.S.; Stadtman, E.R. Protein oxidation in aging, disease, and oxidative stress. J. Biol. Chem. 1997, 272, 20313-20316.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 20313-20316
-
-
Berlett, B.S.1
Stadtman, E.R.2
-
103
-
-
1842634504
-
Proteomic identification of specific oxidized proteins in ApoE-knockout mice: Relevance to Alzheimer's disease
-
Choi, J.; Forster, M.J.; McDonald, S.R.; Weintraub, S.T.; Carroll, C.A.; Gracy, R.W. Proteomic identification of specific oxidized proteins in ApoE-knockout mice: Relevance to Alzheimer's disease. Free Radic. Biol. Med. 2004, 36, 1155-1162.
-
(2004)
Free Radic. Biol. Med
, vol.36
, pp. 1155-1162
-
-
Choi, J.1
Forster, M.J.2
McDonald, S.R.3
Weintraub, S.T.4
Carroll, C.A.5
Gracy, R.W.6
-
104
-
-
34249741418
-
Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions
-
Yaguchi, T.; Aida, S.; Kaul, S.C.; Wadhwa, R. Involvement of mortalin in cellular senescence from the perspective of its mitochondrial import, chaperone, and oxidative stress management functions. Ann. N. Y. Acad. Sci. 2007, 1100, 306-311.
-
(2007)
Ann. N.Y. Acad. Sci
, vol.1100
, pp. 306-311
-
-
Yaguchi, T.1
Aida, S.2
Kaul, S.C.3
Wadhwa, R.4
-
105
-
-
33645808672
-
Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease
-
Mahley, R.W.; Weisgraber, K.H.; Huang, Y. Apolipoprotein E4: A causative factor and therapeutic target in neuropathology, including Alzheimer's disease. Proc. Natl. Acad. Sci. USA 2006, 103, 5644-5651.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 5644-5651
-
-
Mahley, R.W.1
Weisgraber, K.H.2
Huang, Y.3
-
106
-
-
0027327267
-
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders, A.M.; Strittmatter, W.J.; Schmechel, D.; George-Hyslop, P.H.; Pericak-Vance, M.A.; Joo, S.H.; Rosi, B.L.; Gusella, J.F.; Crapper-MacLachlan, D.R.; Alberts, M.J.; et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993, 43, 1467-1472.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
Rosi, B.L.7
Gusella, J.F.8
Crapper-McLachlan, D.R.9
Alberts, M.J.10
-
107
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter, W.J.; Saunders, A.M.; Schmechel, D.; Pericak-Vance, M.; Enghild, J.; Salvesen, G.S.; Roses, A.D. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. USA 1993, 90, 1977-1981.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
Roses, A.D.7
-
108
-
-
12044254746
-
Binding of human apolipoprotein E to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
-
Strittmatter, W.J.; Weisgraber, K.H.; Huang, D.Y.; Dong, L.M.; Salvesen, G.S.; Pericak-Vance, M.; Schmechel, D.; Saunders, A.M.; Goldgaber, D.; Roses, A.D. Binding of human apolipoprotein E to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease. Proc. Natl. Acad. Sci. USA 1993, 90, 8098-8102.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8098-8102
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Huang, D.Y.3
Dong, L.M.4
Salvesen, G.S.5
Pericak-Vance, M.6
Schmechel, D.7
Saunders, A.M.8
Goldgaber, D.9
Roses, A.D.10
-
109
-
-
0029125857
-
Aging, energy, and oxidative stress in neurodegenerative diseases
-
Beal, M.F. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann. Neurol. 1995, 38, 357-366.
-
(1995)
Ann. Neurol
, vol.38
, pp. 357-366
-
-
Beal, M.F.1
-
110
-
-
0035430788
-
Failure of the ubiquitin-proteasome system in Parkinson's disease
-
McNaught, K.S.; Olanow, C.W.; Halliwell, B.; Isacson, O.; Jenner, P. Failure of the ubiquitin-proteasome system in Parkinson's disease. Nat. Rev. Neurosci. 2001, 2, 589-594.
-
(2001)
Nat. Rev. Neurosci
, vol.2
, pp. 589-594
-
-
McNaught, K.S.1
Olanow, C.W.2
Halliwell, B.3
Isacson, O.4
Jenner, P.5
-
112
-
-
2542596183
-
Parkinson's disease
-
Samii, A.; Nutt, J.G.; Ransom, B.R. Parkinson's disease. Lancet 2004, 363, 1783-1793.
-
(2004)
Lancet
, vol.363
, pp. 1783-1793
-
-
Samii, A.1
Nutt, J.G.2
Ransom, B.R.3
-
113
-
-
39249083911
-
Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease
-
Van Laar, V.S.; Dukes, A.A.; Cascio, M.; Hastings, T.G. Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: Implications for Parkinson disease. Neurobiol. Dis. 2008, 29, 477-489.
-
(2008)
Neurobiol. Dis
, vol.29
, pp. 477-489
-
-
Van Laar, V.S.1
Dukes, A.A.2
Cascio, M.3
Hastings, T.G.4
-
114
-
-
0042528615
-
Nitric oxide and reactive oxygen species in Parkinson's disease
-
Tieu, K.; Ischiropoulos, H.; Przedborski, S. Nitric oxide and reactive oxygen species in Parkinson's disease. IUBMB Life 2003, 55, 329-335.
-
(2003)
IUBMB Life
, vol.55
, pp. 329-335
-
-
Tieu, K.1
Ischiropoulos, H.2
Przedborski, S.3
-
115
-
-
0034802764
-
Mitochondrial import driving forces: Enhanced trapping by matrix Hsp70 stimulates translocation and reduces the membrane potential dependence of loosely folded preproteins
-
Geissler, A.; Rassow, J.; Pfanner, N.; Voos, W. Mitochondrial import driving forces: Enhanced trapping by matrix Hsp70 stimulates translocation and reduces the membrane potential dependence of loosely folded preproteins. Mol. Cell. Biol. 2001, 21, 7097-7104.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 7097-7104
-
-
Geissler, A.1
Rassow, J.2
Pfanner, N.3
Voos, W.4
-
116
-
-
78649300971
-
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy
-
VDAC1 is dispensable for both
-
Narendra, D.; Kane, L.A.; Hauser, D.N.; Fearnley, I.M.; Youle, R.J. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both. Autophagy 2010, 6, 1090-1106.
-
(2010)
Autophagy
, vol.6
, pp. 1090-1106
-
-
Narendra, D.1
Kane, L.A.2
Hauser, D.N.3
Fearnley, I.M.4
Youle, R.J.5
-
117
-
-
43049119301
-
Structural effects of Parkinson's disease linked DJ-1 mutations
-
Malgieri, G.; Eliezer, D. Structural effects of Parkinson's disease linked DJ-1 mutations. Protein Sci. 2008, 17, 855-868.
-
(2008)
Protein Sci
, vol.17
, pp. 855-868
-
-
Malgieri, G.1
Eliezer, D.2
-
118
-
-
25444514752
-
Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress
-
Li, H.M.; Niki, T.; Taira, T.; Iguchi-Ariga, S.M.; Ariga, H. Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress. Free Radic. Res. 2005, 39, 1091-1099.
-
(2005)
Free Radic. Res
, vol.39
, pp. 1091-1099
-
-
Li, H.M.1
Niki, T.2
Taira, T.3
Iguchi-Ariga, S.M.4
Ariga, H.5
-
119
-
-
0034329742
-
Apoptosis in neurodegenerative disorders
-
Mattson, M.P. Apoptosis in neurodegenerative disorders. Nat. Rev. Mol. Cell. Biol. 2000, 1, 120-129.
-
(2000)
Nat. Rev. Mol. Cell. Biol
, vol.1
, pp. 120-129
-
-
Mattson, M.P.1
-
120
-
-
0026058318
-
Cell death during development of the nervous system
-
Oppenheim, R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 1991, 14, 453-501.
-
(1991)
Annu. Rev. Neurosci
, vol.14
, pp. 453-501
-
-
Oppenheim, R.W.1
-
121
-
-
1842504355
-
Metal-catalyzed disruption of membrane protein and lipid signaling in the pathogenesis of neurodegenerative disorders
-
Mattson, M.P. Metal-catalyzed disruption of membrane protein and lipid signaling in the pathogenesis of neurodegenerative disorders. Ann. N. Y. Acad. Sci. 2004, 1012, 37-50.
-
(2004)
Ann. N.Y. Acad. Sci
, vol.1012
, pp. 37-50
-
-
Mattson, M.P.1
|