Simultaneous detection of changes in protein expression and oxidative modification as a function of age and APOE genotype

Journal of Proteome Research

Volumn 10, Issue 4, 2011, Pages 1632-1644

  Dekroon, Robert M ^a   Osorio, Cristina ^a   Robinette, Jennifer B ^a   Mocanu, Mihaela ^a   Winnik, Witold M ^b   Alzate, Oscar ^a,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c 438A Taylor Hall CB 7090 ^*  (United States)

Author keywords

3; 6; aldehyde labeling; Alzheimers disease; APOE genotype; carbonylation; oxidation; Peroxiredoxin 2; proteomics

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; CARBONYL DERIVATIVE; HYDROXYLAMINE; PEROXIREDOXIN 2; PEROXIREDOXIN 3; PEROXIREDOXIN 6;

AGING; ANIMAL TISSUE; ARTICLE; DIFFERENTIAL IN GEL ELECTROPHORESIS; FLUORESCENCE; GEL ELECTROPHORESIS; GENOTYPE; HIPPOCAMPUS; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AGING; ANIMALS; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; GENOTYPE; HUMANS; MASS SPECTROMETRY; MICE; MICE, TRANSGENIC; OXIDATION-REDUCTION; PRINCIPAL COMPONENT ANALYSIS; TWO-DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

ALEXA; MUS;

EID: 79953674524     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr1009788     Document Type: Article

References (38)

1. Danielson, S. R.; Andersen, J. K. Oxidative and nitrative protein modifications in Parkinsons disease Free Radic. Biol. Med. 2008, 44 (10) 1787-94
2. Telci, A.; Cakatay, U.; Salman, S.; Satman, I.; Sivas, A. Oxidative protein damage in early stage Type 1 diabetic patients Diabetes Res. Clin. Pract. 2000, 50 (3) 213-23
3. Brennan, M. L.; Hazen, S. L. Amino acid and protein oxidation in cardiovascular disease Amino Acids 2003, 25 (3-4) 365-74 (Pubitemid 38041272)
4. Butterfield, D. A.; Drake, J.; Pocernich, C.; Castegna, A. Evidence of oxidative damage in Alzheimers disease brain: central role for amyloid beta-peptide Trends Mol. Med. 2001, 7 (12) 548-54 (Pubitemid 33127140)
5. Markesbery, W. R. Oxidative stress hypothesis in Alzheimers disease Free Radic. Biol. Med. 1997, 23 (1) 134-47 (Pubitemid 27217017)
6. Sultana, R.; Perluigi, M.; Butterfield, D. A. Protein oxidation and lipid peroxidation in brain of subjects with Alzheimers disease: insights into mechanism of neurodegeneration from redox proteomics Antioxid. Redox Signal. 2006, 8 (11-12) 2021-37 (Pubitemid 46499264)
7. Sultana, R.; Perluigi, M.; Butterfield, D. A. Oxidatively modified proteins in Alzheimers disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis Acta Neuropathol. 2009, 118 (1) 131-50
8. Mahley, R. W.; Huang, Y.; Apolipoprotein, E from atherosclerosis to Alzheimers disease and beyond Curr. Opin. Lipidol. 1999, 10 (3) 207-17
9. Saunders, A. M.; Strittmatter, W. J.; Schmechel, D.; George-Hyslop, P. H.; Pericak-Vance, M. A.; Joo, S. H.; Rosi, B. L.; Gusella, J. F.; Crapper-MacLachlan, D. R.; Alberts, M. J. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimers disease Neurology 1993, 43 (8) 1467-72 (Pubitemid 23230526)
10. Strittmatter, W. J.; Saunders, A. M.; Schmechel, D.; Pericak-Vance, M.; Enghild, J.; Salvesen, G. S.; Roses, A. D.; Apolipoprotein, E high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease Proc. Natl. Acad. Sci. U.S.A. 1993, 90 (5) 1977-81 (Pubitemid 23069980)
11. Mahley, R. W.; Weisgraber, K. H.; Huang, Y. Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimers disease Proc. Natl. Acad. Sci. U.S.A. 2006, 103 (15) 5644-51
12. Reed, T. T.; Sultana, R.; Butterfield, D. A. Redox Proteomics of Oxidatively Modified Brain Proteins in Mild Cognitive Impairment. In Neuroproteomics; Alzate, O., Ed.; CRC Press: Boca Raton, FL, 2009; p 322.
13. Stadtman, E. R. Protein oxidation in aging and age-related diseases Ann. N.Y. Acad. Sci. 2001, 928, 22-38 (Pubitemid 32386064)
14. Stadtman, E. R.; Berlett, B. S. Reactive oxygen-mediated protein oxidation in aging and disease Chem. Res. Toxicol. 1997, 10 (5) 485-94 (Pubitemid 27217204)
15. Stadtman, E. R. Protein oxidation and aging Science 1992, 257 (5074) 1220-4
16. Osorio, C.; Sullivan, P. M.; He, D. N.; Mace, B. E.; Ervin, J. F.; Strittmatter, W. J.; Alzate, O. Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice Neurobiol. Aging 2007, 28 (12) 1853-62 (Pubitemid 47539697)
17. Speicher, K. D.; Kolbas, O.; Harper, S.; Speicher, D. W. Systematic analysis of peptide recoveries from in-gel digestions for protein identifications in proteome studies J. Biomol. Tech. 2000, 11 (2) 74-86
18. Berth, M.; Moser, F. M.; Kolbe, M.; Bernhardt, J. The state of the art in the analysis of two-dimensional gel electrophoresis images Appl. Microbiol. Biotechnol. 2007, 76 (6) 1223-43 (Pubitemid 47459790)
19. Friedman, D. B.; Lilley, K. S. Optimizing the difference gel electrophoresis (DIGE) technology Methods Mol. Biol. 2008, 428, 93-124
20. Calabrese, V.; Stella, A. M.; Butterfield, D. A.; Scapagnini, G. Redox regulation in neurodegeneration and longevity: role of the heme oxygenase and HSP70 systems in brain stress tolerance Antioxid. Redox Signal. 2004, 6 (5) 895-913 (Pubitemid 39237943)
21. Castegna, A.; Aksenov, M.; Thongboonkerd, V.; Klein, J. B.; Pierce, W. M.; Booze, R.; Markesbery, W. R.; Butterfield, D. A. Proteomic identification of oxidatively modified proteins in Alzheimers disease brain. Part II: dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71 J. Neurochem. 2002, 82 (6) 1524-32
22. Butterfield, D. A.; Lange, M. L. Multifunctional roles of enolase in Alzheimers disease brain: beyond altered glucose metabolism J. Neurochem. 2009, 111 (4) 915-33
23. Iqbal, K.; Grundke-Iqbal, I.; Zaidi, T.; Merz, P. A.; Wen, G. Y.; Shaikh, S. S.; Wisniewski, H. M.; Alafuzoff, I.; Winblad, B. Defective brain microtubule assembly in Alzheimers disease Lancet 1986, 2 (8504) 421-6 (Pubitemid 16047953)
24. Yang, F.; Sun, X.; Beech, W.; Teter, B.; Wu, S.; Sigel, J.; Vinters, H. V.; Frautschy, S. A.; Cole, G. M. Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimers disease Am. J. Pathol. 1998, 152 (2) 379-89 (Pubitemid 28106384)
25. Nystrom, T. Role of oxidative carbonylation in protein quality control and senescence EMBO J. 2005, 24 (7) 1311-7 (Pubitemid 40593052)
26. Martinez, A.; Portero-Otin, M.; Pamplona, R.; Ferrer, I. Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates Brain Pathol. 2010, 20 (2) 281-97
27. Di Domenico, F.; Sultana, R.; Tiu, G. F.; Scheff, N. N.; Perluigi, M.; Cini, C.; Butterfield, D. A. Protein levels of heat shock proteins 27, 32, 60, 70, 90 and thioredoxin-1 in amnestic mild cognitive impairment: an investigation on the role of cellular stress response in the progression of Alzheimer disease Brain Res. 2010, 1333, 72-81
28. Miyata, M.; Smith, J. D. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides Nat. Genet. 1996, 14 (1) 55-61 (Pubitemid 26301547)
29. Pulido, R.; Jimenez-Escrig, A.; Orensanz, L.; Saura-Calixto, F. Study of plasma antioxidant status in Alzheimers disease Eur. J. Neurol. 2005, 12 (7) 531-5 (Pubitemid 40956810)
30. Tamaoka, A.; Miyatake, F.; Matsuno, S.; Ishii, K.; Nagase, S.; Sahara, N.; Ono, S.; Mori, H.; Wakabayashi, K.; Tsuji, S.; Takahashi, H.; Shoji, S. Apolipoprotein E allele-dependent antioxidant activity in brains with Alzheimers disease Neurology 2000, 54 (12) 2319-21 (Pubitemid 30416286)
31. Ferguson, S.; Mouzon, B.; Kayihan, G.; Wood, M.; Poon, F.; Doore, S.; Mathura, V.; Humphrey, J.; Osteen, B.; Hayes, R.; Roses, A.; Mullan, M.; Crawford, F. Apolipoprotein E genotype and oxidative stress response to traumatic brain injury Neuroscience 2010, 168 (3) 811-9
32. Korolainen, M. A.; Pirttila, T. Cerebrospinal fluid, serum and plasma protein oxidation in Alzheimers disease Acta Neurol. Scand. 2009, 119 (1) 32-8
33. Yao, J.; Taylor, M.; Davey, F.; Ren, Y.; Aiton, J.; Coote, P.; Fang, F.; Chen, J. X.; Yan, S. D.; Gunn-Moore, F. J. Interaction of amyloid binding alcohol dehydrogenase/Abeta mediates up-regulation of peroxiredoxin II in the brains of Alzheimers disease patients and a transgenic Alzheimers disease mouse model Mol. Cell. Neurosci. 2007, 35 (2) 377-82 (Pubitemid 46843572)
34. Kim, S. U.; Jin, M. H.; Kim, Y. S.; Lee, S. H.; Cho, Y. S.; Cho, K. J.; Lee, K. S.; Kim, Y. I.; Kim, G. W.; Kim, J. M.; Lee, T. H.; Lee, Y. H.; Shong, M.; Kim, H. C.; Chang, K. T.; Yu, D. Y.; Lee, D. S. Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage Neurobiol. Aging 2009, 10.1016/j.neurobiolaging.2009.05.17
35. Power, J. H.; Asad, S.; Chataway, T. K.; Chegini, F.; Manavis, J.; Temlett, J. A.; Jensen, P. H.; Blumbergs, P. C.; Gai, W. P. Peroxiredoxin 6 in human brain: molecular forms, cellular distribution and association with Alzheimers disease pathology Acta Neuropathol. 2008, 115 (6) 611-22
36. Hattori, F.; Oikawa, S. Peroxiredoxins in the central nervous system Subcell Biochem. 2007, 44, 357-74
37. Hattori, F.; Murayama, N.; Noshita, T.; Oikawa, S. Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo J. Neurochem. 2003, 86 (4) 860-8 (Pubitemid 36988798)
38. Abbas, K.; Breton, J.; Drapier, J. C. The interplay between nitric oxide and peroxiredoxins Immunobiology 2008, 213 (9-10) 815-22