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Volumn 28, Issue 5, 2008, Pages 1009-1016

Overexpression of mitochondrial Hsp70/Hsp75 protects astrocytes against ischemic injury in vitro

Author keywords

Astrocyte; Heat shock protein; Ischemia; Mitochondria; Mortalin; Oxidative stress

Indexed keywords

ADENOSINE TRIPHOSPHATE; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 75; REACTIVE OXYGEN METABOLITE;

EID: 42549112997     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600600     Document Type: Article
Times cited : (106)

References (45)
  • 1
    • 0035909948 scopus 로고    scopus 로고
    • Different responses of astrocytes and neurons to nitric oxide: The role of glycolytically generated ATP in astrocyte protection
    • Almeida A, Almeida J, Bolanos JP, Moncada S (2001) Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection. Proc Natl Acad Sci USA 98:15294-9
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 15294-15299
    • Almeida, A.1    Almeida, J.2    Bolanos, J.P.3    Moncada, S.4
  • 2
    • 1542317747 scopus 로고    scopus 로고
    • Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection
    • Bambrick L, Kristian T, Fiskum G (2004) Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection. Neurochem Res 29:601-8
    • (2004) Neurochem Res , vol.29 , pp. 601-608
    • Bambrick, L.1    Kristian, T.2    Fiskum, G.3
  • 5
    • 0036186681 scopus 로고    scopus 로고
    • Implication of PBP74/mortalin/GRP75 in the radio-adaptive response
    • Carette J, Lehnert S, Chow TY (2002) Implication of PBP74/mortalin/GRP75 in the radio-adaptive response. Int J Radiat Biol 78:183-90
    • (2002) Int J Radiat Biol , vol.78 , pp. 183-190
    • Carette, J.1    Lehnert, S.2    Chow, T.Y.3
  • 7
    • 20344364186 scopus 로고    scopus 로고
    • Astrocytic contributions to bioenergetics of cerebral ischemia
    • Dienel GA, Hertz L (2005) Astrocytic contributions to bioenergetics of cerebral ischemia. Glia 50:362-88
    • (2005) Glia , vol.50 , pp. 362-388
    • Dienel, G.A.1    Hertz, L.2
  • 8
    • 0033118649 scopus 로고    scopus 로고
    • Contributions of mitochondria to animal physiology: From homeostatic sensor to calcium signalling and cell death
    • Duchen MR (1999) Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death. J Physiol 516(Part 1):1-17
    • (1999) J Physiol , vol.516 , Issue.PART 1 , pp. 1-17
    • Duchen, M.R.1
  • 9
    • 0029055091 scopus 로고
    • Glia modulate the response of murine cortical neurons to excitotoxicity: Glia exacerbate AMPA neurotoxicity
    • Dugan LL, Bruno VM, Amagasu SM, Giffard RG (1995) Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity. J Neurosci 15:4545-55
    • (1995) J Neurosci , vol.15 , pp. 4545-4555
    • Dugan, L.L.1    Bruno, V.M.2    Amagasu, S.M.3    Giffard, R.G.4
  • 10
    • 0033782296 scopus 로고    scopus 로고
    • Mitochondrial participation in ischemic and traumatic neural cell death
    • Fiskum G (2000) Mitochondrial participation in ischemic and traumatic neural cell death. J Neurotrauma 17:843-55
    • (2000) J Neurotrauma , vol.17 , pp. 843-855
    • Fiskum, G.1
  • 12
    • 4544229923 scopus 로고    scopus 로고
    • Molecular chaperone GRP75 reprove cells from injury caused by glucose deprivation
    • Gao CX, Zhang SQ, Yin Z, Liu W (2003) Molecular chaperone GRP75 reprove cells from injury caused by glucose deprivation. Shi Yan Sheng Wu Xue Bao 36:381-7
    • (2003) Shi Yan Sheng Wu Xue Bao , vol.36 , pp. 381-387
    • Gao, C.X.1    Zhang, S.Q.2    Yin, Z.3    Liu, W.4
  • 13
    • 0348223798 scopus 로고    scopus 로고
    • Many mechanisms for hsp70 protection from cerebral ischemia
    • Giffard RG, Yenari MA (2004) Many mechanisms for hsp70 protection from cerebral ischemia. J Neurosurg Anesthesiol 16:53-61
    • (2004) J Neurosurg Anesthesiol , vol.16 , pp. 53-61
    • Giffard, R.G.1    Yenari, M.A.2
  • 14
    • 0031026233 scopus 로고    scopus 로고
    • p75, a member of the heat shock protein family, undergoes tyrosine phosphorylation in response to oxidative stress
    • Hadari YR, Haring HU, Zick Y (1997) p75, a member of the heat shock protein family, undergoes tyrosine phosphorylation in response to oxidative stress. J Biol Chem 272:657-62
    • (1997) J Biol Chem , vol.272 , pp. 657-662
    • Hadari, Y.R.1    Haring, H.U.2    Zick, Y.3
  • 15
    • 33846423878 scopus 로고    scopus 로고
    • Energy metabolism in astrocytes: High rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis
    • Hertz L, Peng L, Dienel GA (2007) Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis. J Cereb Blood Flow Metab 27:219-49
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 219-249
    • Hertz, L.1    Peng, L.2    Dienel, G.A.3
  • 16
    • 34547138950 scopus 로고    scopus 로고
    • Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis
    • Hua G, Zhang Q, Fan Z (2007) Heat shock protein 75 (TRAP1) antagonizes reactive oxygen species generation and protects cells from granzyme M-mediated apoptosis. J Biol Chem 282:20553-60
    • (2007) J Biol Chem , vol.282 , pp. 20553-20560
    • Hua, G.1    Zhang, Q.2    Fan, Z.3
  • 17
    • 33846426804 scopus 로고    scopus 로고
    • Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species
    • Im CN, Lee JS, Zheng Y, Seo JS (2007) Iron chelation study in a normal human hepatocyte cell line suggests that tumor necrosis factor receptor-associated protein 1 (TRAP1) regulates production of reactive oxygen species. J Cell Biochem 100:474-86
    • (2007) J Cell Biochem , vol.100 , pp. 474-486
    • Im, C.N.1    Lee, J.S.2    Zheng, Y.3    Seo, J.S.4
  • 18
    • 33847651284 scopus 로고    scopus 로고
    • Three faces of mortalin: A housekeeper, guardian and killer
    • Kaul SC, Deocaris CC, Wadhwa R (2007) Three faces of mortalin: a housekeeper, guardian and killer. Exp Gerontol 42:263-74
    • (2007) Exp Gerontol , vol.42 , pp. 263-274
    • Kaul, S.C.1    Deocaris, C.C.2    Wadhwa, R.3
  • 20
    • 0031793127 scopus 로고    scopus 로고
    • Heat shock protein 70 kDa: Molecular biology, biochemistry, and physiology
    • Kiang JG, Tsokos GC (1998) Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology. Pharmacol Ther 80:183-201
    • (1998) Pharmacol Ther , vol.80 , pp. 183-201
    • Kiang, J.G.1    Tsokos, G.C.2
  • 21
    • 0033864758 scopus 로고    scopus 로고
    • Mitochondrial protein import motor: The ATPase domain of matrix Hsp70 is crucial for binding to Tim44, while the peptide binding domain and the carboxyterminal segment play a stimulatory role
    • Krimmer T, Rassow J, Kunau WH, Voos W, Pfanner N (2000) Mitochondrial protein import motor: the ATPase domain of matrix Hsp70 is crucial for binding to Tim44, while the peptide binding domain and the carboxyterminal segment play a stimulatory role. Mol Cell Biol 20:5879-87
    • (2000) Mol Cell Biol , vol.20 , pp. 5879-5887
    • Krimmer, T.1    Rassow, J.2    Kunau, W.H.3    Voos, W.4    Pfanner, N.5
  • 22
    • 4644301795 scopus 로고    scopus 로고
    • A proteome analysis of the arsenite response in cultured lung cells: Evidence for in vitro oxidative stress-induced apoptosis
    • Lau AT, He QY, Chiu JF (2004) A proteome analysis of the arsenite response in cultured lung cells: evidence for in vitro oxidative stress-induced apoptosis. Biochem J 382:641-50
    • (2004) Biochem J , vol.382 , pp. 641-650
    • Lau, A.T.1    He, Q.Y.2    Chiu, J.F.3
  • 23
    • 0035423875 scopus 로고    scopus 로고
    • The glucose-regulated proteins: Stress induction and clinical applications
    • Lee AS (2001) The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci 26:504-10
    • (2001) Trends Biochem Sci , vol.26 , pp. 504-510
    • Lee, A.S.1
  • 24
    • 14244268253 scopus 로고    scopus 로고
    • Effect of GRP75/mthsp70/PBP74/ mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells
    • Liu Y, Liu W, Song XD, Zuo J (2005) Effect of GRP75/mthsp70/PBP74/ mortalin overexpression on intracellular ATP level, mitochondrial membrane potential and ROS accumulation following glucose deprivation in PC12 cells. Mol Cell Biochem 268:45-51
    • (2005) Mol Cell Biochem , vol.268 , pp. 45-51
    • Liu, Y.1    Liu, W.2    Song, X.D.3    Zuo, J.4
  • 25
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo EH, Dalkara T, Moskowitz MA (2003) Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci 4:399-415
    • (2003) Nat Rev Neurosci , vol.4 , pp. 399-415
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 26
    • 0020582124 scopus 로고
    • Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus
    • Mann R, Mulligan RC, Baltimore D (1983) Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell 33:153-9
    • (1983) Cell , vol.33 , pp. 153-159
    • Mann, R.1    Mulligan, R.C.2    Baltimore, D.3
  • 27
    • 0028902781 scopus 로고
    • Cloning of rat grp75, an hsp70-family member, and its expression in normal and ischemic brain
    • Massa SM, Longo FM, Zuo J, Wang S, Chen J, Sharp FR (1995) Cloning of rat grp75, an hsp70-family member, and its expression in normal and ischemic brain. J Neurosci Res 40:807-19
    • (1995) J Neurosci Res , vol.40 , pp. 807-819
    • Massa, S.M.1    Longo, F.M.2    Zuo, J.3    Wang, S.4    Chen, J.5    Sharp, F.R.6
  • 28
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • 2, 984-986
    • Miller AD, Rosman GJ (1989) Improved retroviral vectors for gene transfer and expression. Biotechniques 7:980-2, 984-986, 989-990
    • (1989) Biotechniques , vol.7
    • Miller, A.D.1    Rosman, G.J.2
  • 29
    • 0036510606 scopus 로고    scopus 로고
    • Mitochondrial protein import: Molecular basis of the ATP-dependent interaction of MtHsp70 with Tim44
    • Moro F, Okamoto K, Donzeau M, Neupert W, Brunner M (2002) Mitochondrial protein import: molecular basis of the ATP-dependent interaction of MtHsp70 with Tim44. J Biol Chem 277:6874-80
    • (2002) J Biol Chem , vol.277 , pp. 6874-6880
    • Moro, F.1    Okamoto, K.2    Donzeau, M.3    Neupert, W.4    Brunner, M.5
  • 30
    • 0037101887 scopus 로고    scopus 로고
    • Effect of Bcl-x(L) overexpression on reactive oxygen species, intracellular calcium, and mitochondrial membrane potential following injury in astrocytes
    • Ouyang YB, Carriedo SG, Giffard RG (2002) Effect of Bcl-x(L) overexpression on reactive oxygen species, intracellular calcium, and mitochondrial membrane potential following injury in astrocytes. Free Radic Biol Med 33:544-51
    • (2002) Free Radic Biol Med , vol.33 , pp. 544-551
    • Ouyang, Y.B.1    Carriedo, S.G.2    Giffard, R.G.3
  • 31
    • 34247345825 scopus 로고    scopus 로고
    • Selective dysfunction of hippocampal CA1 astrocytes contributes to delayed neuronal damage after transient forebrain ischemia
    • Ouyang YB, Voloboueva LA, Xu LJ, Giffard RG (2007) Selective dysfunction of hippocampal CA1 astrocytes contributes to delayed neuronal damage after transient forebrain ischemia. J Neurosci 27:4253-60
    • (2007) J Neurosci , vol.27 , pp. 4253-4260
    • Ouyang, Y.B.1    Voloboueva, L.A.2    Xu, L.J.3    Giffard, R.G.4
  • 32
    • 33745432541 scopus 로고    scopus 로고
    • Overexpression of inducible heat shock protein 70 and its mutants in astrocytes is associated with maintenance of mitochondrial physiology during glucose deprivation stress
    • Ouyang YB, Xu LJ, Sun YJ, Giffard RG (2006) Overexpression of inducible heat shock protein 70 and its mutants in astrocytes is associated with maintenance of mitochondrial physiology during glucose deprivation stress. Cell Stress Chaperones 11:180-6
    • (2006) Cell Stress Chaperones , vol.11 , pp. 180-186
    • Ouyang, Y.B.1    Xu, L.J.2    Sun, Y.J.3    Giffard, R.G.4
  • 33
    • 0031050684 scopus 로고    scopus 로고
    • Vulnerability to glucose deprivation injury correlates with glutathione levels in astrocytes
    • Papadopoulos MC, Koumenis IL, Dugan LL, Giffard RG (1997) Vulnerability to glucose deprivation injury correlates with glutathione levels in astrocytes. Brain Res 748:151-6
    • (1997) Brain Res , vol.748 , pp. 151-156
    • Papadopoulos, M.C.1    Koumenis, I.L.2    Dugan, L.L.3    Giffard, R.G.4
  • 34
    • 0342618475 scopus 로고    scopus 로고
    • Increasing vulnerability of astrocytes to oxidative injury with age despite constant antioxidant defenses
    • Papadopoulos MC, Koumenis IL, Yuan TY, Giffard RG (1998) Increasing vulnerability of astrocytes to oxidative injury with age despite constant antioxidant defenses. Neuroscience 82:915-25
    • (1998) Neuroscience , vol.82 , pp. 915-925
    • Papadopoulos, M.C.1    Koumenis, I.L.2    Yuan, T.Y.3    Giffard, R.G.4
  • 35
    • 34547127902 scopus 로고    scopus 로고
    • PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
    • Pridgeon JW, Olzmann JA, Chin LS, Li L (2007) PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biol 5:e172
    • (2007) PLoS Biol , vol.5
    • Pridgeon, J.W.1    Olzmann, J.A.2    Chin, L.S.3    Li, L.4
  • 36
    • 0036257364 scopus 로고    scopus 로고
    • Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74
    • Schwarzer C, Barnikol-Watanabe S, Thinnes FP, Hilschmann N (2002) Voltage-dependent anion-selective channel (VDAC) interacts with the dynein light chain Tctex1 and the heat-shock protein PBP74. Int J Biochem Cell Biol 34:1059-70
    • (2002) Int J Biochem Cell Biol , vol.34 , pp. 1059-1070
    • Schwarzer, C.1    Barnikol-Watanabe, S.2    Thinnes, F.P.3    Hilschmann, N.4
  • 37
    • 0025785711 scopus 로고
    • Heat shock protein hsp72 induction in cortical and striatal astrocytes and neurons following infarction
    • Sharp FR, Lowenstein D, Simon R, Hisanaga K (1991) Heat shock protein hsp72 induction in cortical and striatal astrocytes and neurons following infarction. J Cereb Blood Flow Metab 11:621-7
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 621-627
    • Sharp, F.R.1    Lowenstein, D.2    Simon, R.3    Hisanaga, K.4
  • 38
    • 0034038708 scopus 로고    scopus 로고
    • Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism?
    • Spitz DR, Sim JE, Ridnour LA, Galoforo SS, Lee YJ (2000) Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism? Ann N Y Acad Sci 899:349-62
    • (2000) Ann N Y Acad Sci , vol.899 , pp. 349-362
    • Spitz, D.R.1    Sim, J.E.2    Ridnour, L.A.3    Galoforo, S.S.4    Lee, Y.J.5
  • 40
    • 0037112550 scopus 로고    scopus 로고
    • Proteome analysis and functional expression identify mortalin as an antiapoptotic gene induced by elevation of [Na+]i/[K+]i ratio in cultured vascular smooth muscle cells
    • Taurin S, Seyrantepe V, Orlov SN, Tremblay TL, Thibault P, Bennett MR, Hamet P, Pshezhetsky AV (2002) Proteome analysis and functional expression identify mortalin as an antiapoptotic gene induced by elevation of [Na+]i/[K+]i ratio in cultured vascular smooth muscle cells. Circ Res 91:915-22
    • (2002) Circ Res , vol.91 , pp. 915-922
    • Taurin, S.1    Seyrantepe, V.2    Orlov, S.N.3    Tremblay, T.L.4    Thibault, P.5    Bennett, M.R.6    Hamet, P.7    Pshezhetsky, A.V.8
  • 41
    • 0038796543 scopus 로고    scopus 로고
    • Overexpression of rat heat shock protein 70 is associated with reduction of early mitochondrial cytochrome C release and subsequent DNA fragmentation after permanent focal ischemia
    • Tsuchiya D, Hong S, Matsumori Y, Shiina H, Kayama T, Swanson RA, Dillman WH, Liu J, Panter SS, Weinstein PR (2003) Overexpression of rat heat shock protein 70 is associated with reduction of early mitochondrial cytochrome C release and subsequent DNA fragmentation after permanent focal ischemia. J Cereb Blood Flow Metab 23:718-27
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 718-727
    • Tsuchiya, D.1    Hong, S.2    Matsumori, Y.3    Shiina, H.4    Kayama, T.5    Swanson, R.A.6    Dillman, W.H.7    Liu, J.8    Panter, S.S.9    Weinstein, P.R.10
  • 42
    • 0033612301 scopus 로고    scopus 로고
    • The protein import motor of mitochondria: Unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70
    • Voisine C, Craig EA, Zufall N, von Ahsen O, Pfanner N, Voos W (1999) The protein import motor of mitochondria: unfolding and trapping of preproteins are distinct and separable functions of matrix Hsp70. Cell 97:565-574
    • (1999) Cell , vol.97 , pp. 565-574
    • Voisine, C.1    Craig, E.A.2    Zufall, N.3    von Ahsen, O.4    Pfanner, N.5    Voos, W.6
  • 43
    • 34547492269 scopus 로고    scopus 로고
    • Inhibition of mitochondrial function in astrocytes: Implications for neuroprotection
    • Voloboueva LA, Suh SW, Swanson RA, Giffard RG (2007) Inhibition of mitochondrial function in astrocytes: implications for neuroprotection. J Neurochem 102:1383-94
    • (2007) J Neurochem , vol.102 , pp. 1383-1394
    • Voloboueva, L.A.1    Suh, S.W.2    Swanson, R.A.3    Giffard, R.G.4
  • 44
    • 4644334657 scopus 로고    scopus 로고
    • Susceptibility to apoptosis varies with time in culture for murine neurons and astrocytes: Changes in gene expression and activity
    • Xu L, Chock VY, Yang EY, Giffard RG (2004) Susceptibility to apoptosis varies with time in culture for murine neurons and astrocytes: changes in gene expression and activity. Neurol Res 26:632-43
    • (2004) Neurol Res , vol.26 , pp. 632-643
    • Xu, L.1    Chock, V.Y.2    Yang, E.Y.3    Giffard, R.G.4
  • 45


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