Overexpression of mitochondrial Hsp70/Hsp75 in rat brain protects mitochondria, reduces oxidative stress, and protects from focal ischemia

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 2, 2009, Pages 365-374

  Xu, Lijun ^a   Voloboueva, Ludmila A ^a   Ouyang, YiBing ^a   Emery, John F ^a   Giffard, Rona G ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Grp75; Mitochondria; Mortalin; Oxidative stress; Stroke; TRAP1

Indexed keywords

4 HYDROXYNONENAL; ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; FREE RADICAL; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 75; HYDROETHIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN MITOCHONDRION; BRAIN NERVE CELL; BRAIN PROTECTION; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVITY; GENE OVEREXPRESSION; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; LIPID PEROXIDATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; BRAIN ISCHEMIA; ELECTRON TRANSPORT; GENE EXPRESSION REGULATION; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; LIPID METABOLISM; MALE; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 59149091608     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2008.125     Document Type: Article

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