The mitochondrial Hsp70-dependent import system actively unfolds preproteins and shortens the lag phase of translocation

EMBO Journal

Volumn 20, Issue 5, 2001, Pages 941-950

  Lim, Joo Hyun ^a   Martin, Falk ^a,b   Guiard, Bernard ^c   Pfanner, Nikolaus ^a   Voos, Wolfgang ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c CENTRE DE GÉNÉTIQUE MOLÉCULAIRE   (France)

Author keywords

Hsp70; Mitochondria; Protein sorting; Protein unfolding; Saccharomyces cerevisiae

Indexed keywords

HEAT SHOCK PROTEIN 70; PROTEIN PRECURSOR;

AMINO TERMINAL SEQUENCE; ARTICLE; MEMBRANE BINDING; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN TARGETING; SACCHAROMYCES CEREVISIAE; TRANSPORT KINETICS;

ANIMALS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HSP70 HEAT-SHOCK PROTEINS; KINETICS; L-LACTATE DEHYDROGENASE; L-LACTATE DEHYDROGENASE (CYTOCHROME); MICE; MITOCHONDRIA; MUTATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; TETRAHYDROFOLATE DEHYDROGENASE; UREA;

SACCHAROMYCES CEREVISIAE;

EID: 0035282966     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.5.941     Document Type: Article

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