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Volumn 13, Issue 12, 2016, Pages 1743-1757

Application of lipid nanoparticles to ocular drug delivery

Author keywords

drug delivery; eye; nanostructured lipid carrier; Solid lipid nanoparticles

Indexed keywords

ACICLOVIR; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIVIRUS AGENT; CHLORAMPHENICOL; GATIFLOXACIN; ITRACONAZOLE; KETOCONAZOLE; LEVOFLOXACIN; LIPID; NANOPARTICLE; TOBRAMYCIN; EYE DROPS;

EID: 84994049083     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1080/17425247.2016.1201059     Document Type: Review
Times cited : (121)

References (122)
  • 1
    • 84940907263 scopus 로고    scopus 로고
    • Recent advances in ocular drug delivery, with special emphasis on lipid based nanocarriers
    • Sah AK, Suresh PK., Recent advances in ocular drug delivery, with special emphasis on lipid based nanocarriers. Recent Pat Nanotechnol. 2015;9(2):94–105.
    • (2015) Recent Pat Nanotechnol , vol.9 , Issue.2 , pp. 94-105
    • Sah, A.K.1    Suresh, P.K.2
  • 2
    • 84948670104 scopus 로고    scopus 로고
    • Ophthalmic applications of lipid-based drug nanocarriers: an update of research and patenting activity
    • Pignatello R, Carbone C, Puglia C, et al. Ophthalmic applications of lipid-based drug nanocarriers:an update of research and patenting activity. Ther Deliv. 2015;6(11):1297–1318.
    • (2015) Ther Deliv , vol.6 , Issue.11 , pp. 1297-1318
    • Pignatello, R.1    Carbone, C.2    Puglia, C.3
  • 3
    • 84931281534 scopus 로고    scopus 로고
    • Lipid nanocarriers (LNC) and their applications in ocular drug delivery
    • Puglia C, Offerta A, Carbone C, et al. Lipid nanocarriers (LNC) and their applications in ocular drug delivery. Curr Med Chem. 2015;22(13):1589–1602.
    • (2015) Curr Med Chem , vol.22 , Issue.13 , pp. 1589-1602
    • Puglia, C.1    Offerta, A.2    Carbone, C.3
  • 4
    • 79251528557 scopus 로고    scopus 로고
    • Ocular anatomy and cross-sectional imaging of the eye
    • Malhotra A, Minja FJ, Crum A. Ocular anatomy and cross-sectional imaging of the eye. Semin Ultrasound CT MRI. 2011;32(1):2–13.
    • (2011) Semin Ultrasound CT MRI , vol.32 , Issue.1 , pp. 2-13
    • Malhotra, A.1    Minja, F.J.2    Crum, A.3
  • 5
    • 0034510044 scopus 로고    scopus 로고
    • Physiological functions of the eye
    • Patil BB, Dowd TC. Physiological functions of the eye. Curr Anaesth Crit Care. 2000;11(6):293–298.
    • (2000) Curr Anaesth Crit Care , vol.11 , Issue.6 , pp. 293-298
    • Patil, B.B.1    Dowd, T.C.2
  • 6
    • 34548364171 scopus 로고    scopus 로고
    • Applied ocular physiology and anatomy
    • Presland A. Applied ocular physiology and anatomy. Anaesth Intens Care Med. 2007;8(9):379–382.
    • (2007) Anaesth Intens Care Med , vol.8 , Issue.9 , pp. 379-382
    • Presland, A.1
  • 7
    • 84891888294 scopus 로고    scopus 로고
    • Ocular anatomy and physiology relevant to anaesthesia
    • Presland A, Price J. Ocular anatomy and physiology relevant to anaesthesia. Anaesth Intens Care Med. 2014;15(1):20–25.
    • (2014) Anaesth Intens Care Med , vol.15 , Issue.1 , pp. 20-25
    • Presland, A.1    Price, J.2
  • 8
  • 9
    • 84888132116 scopus 로고    scopus 로고
    • Tear film mucins: front line defenders of the ocular surface; comparison with airway and gastrointestinal tract Mucins
    • Hodges RR, Dartt DA. Tear film mucins:front line defenders of the ocular surface; comparison with airway and gastrointestinal tract Mucins. Exp Eye Res. 2013;117:62–78.
    • (2013) Exp Eye Res , vol.117 , pp. 62-78
    • Hodges, R.R.1    Dartt, D.A.2
  • 10
    • 0842331890 scopus 로고    scopus 로고
    • Functional aspects of the tear film lipid layer
    • Bron AJ, Tiffany JM, Gouveia SM, et al. Functional aspects of the tear film lipid layer. Exp Eye Res. 2004;78:347–360.
    • (2004) Exp Eye Res , vol.78 , pp. 347-360
    • Bron, A.J.1    Tiffany, J.M.2    Gouveia, S.M.3
  • 11
    • 0842331892 scopus 로고    scopus 로고
    • Interaction of EGF family growth factors and neurotransmitters in regulating lacrimal gland secretion
    • Dartt DA. Interaction of EGF family growth factors and neurotransmitters in regulating lacrimal gland secretion. Exp Eye Res. 2004;78:337–345.
    • (2004) Exp Eye Res , vol.78 , pp. 337-345
    • Dartt, D.A.1
  • 12
    • 84874679837 scopus 로고    scopus 로고
    • Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers
    • Gan L, Wang J, Jiang M, et al. Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers. Drug Discov Today. 2013;18:290–297.• Describes marketed lipid based nanoformulations.
    • (2013) Drug Discov Today , vol.18 , pp. 290-297
    • Gan, L.1    Wang, J.2    Jiang, M.3
  • 14
    • 84886198695 scopus 로고    scopus 로고
    • The cornea and Sclera
    • Springer Science+Business Media, LLC
    • Meek KM. The cornea and Sclera. In:Fratzl P, editor. Collagen:structure and mechanics. New York (NY):Springer Science+Business Media, LLC; 2008.
    • (2008) Collagen: structure and mechanics
    • Meek, K.M.1    Fratzl, P.2
  • 15
    • 77957807681 scopus 로고    scopus 로고
    • Ocular anatomy and physiology relevant to anaesthesia
    • Presland A, Myatt J. Ocular anatomy and physiology relevant to anaesthesia. Anaesth Intens Care Med. 2010;11:438–443.
    • (2010) Anaesth Intens Care Med , vol.11 , pp. 438-443
    • Presland, A.1    Myatt, J.2
  • 16
    • 84922793574 scopus 로고    scopus 로고
    • Proteomic analysis of human vitreous humor
    • Murthy KR, Goel R, Subbannayya Y, et al. Proteomic analysis of human vitreous humor. Clin Proteomics. 2014;11(1):29.
    • (2014) Clin Proteomics , vol.11 , Issue.1 , pp. 29
    • Murthy, K.R.1    Goel, R.2    Subbannayya, Y.3
  • 17
    • 77954416176 scopus 로고    scopus 로고
    • Feasibility of lipid nanoparticles for ocular delivery of anti-inflammatory drugs
    • Souto EB, Doktorovova S, Gonzalez-Mira E, et al. Feasibility of lipid nanoparticles for ocular delivery of anti-inflammatory drugs. Curr Eye Res. 2010;35(7):537–552.
    • (2010) Curr Eye Res , vol.35 , Issue.7 , pp. 537-552
    • Souto, E.B.1    Doktorovova, S.2    Gonzalez-Mira, E.3
  • 19
    • 84934443699 scopus 로고    scopus 로고
    • The blood-retina barrier: tight junctions and barrier modulation
    • Campbell M, Humphries P. The blood-retina barrier:tight junctions and barrier modulation. Adv Exp Med Biol. 2012;763:70–84.
    • (2012) Adv Exp Med Biol , vol.763 , pp. 70-84
    • Campbell, M.1    Humphries, P.2
  • 20
    • 77953173751 scopus 로고    scopus 로고
    • New techniques for drug delivery to the posterior eye segment
    • Eljarrat-Binstock E, Pe’er J, Domb AJ. New techniques for drug delivery to the posterior eye segment. Pharm Res. 2010;27:530–543.
    • (2010) Pharm Res , vol.27 , pp. 530-543
    • Eljarrat-Binstock, E.1    Pe’er, J.2    Domb, A.J.3
  • 21
    • 39149121847 scopus 로고    scopus 로고
    • Current and future ophthalmic drug delivery systems. A shift to the posterior segment
    • Del Amo EM, Urtti A. Current and future ophthalmic drug delivery systems. A shift to the posterior segment. Drug Discov Today. 2008;13:135–143.
    • (2008) Drug Discov Today , vol.13 , pp. 135-143
    • Del Amo, E.M.1    Urtti, A.2
  • 23
    • 0037319276 scopus 로고    scopus 로고
    • Drug delivery to the retina: challenges and opportunities
    • Duvvuri S, Majumdar S, Mitra AK. Drug delivery to the retina:challenges and opportunities. Expert Opin Biol Ther. 2003;3:45–56.
    • (2003) Expert Opin Biol Ther , vol.3 , pp. 45-56
    • Duvvuri, S.1    Majumdar, S.2    Mitra, A.K.3
  • 24
    • 34247215173 scopus 로고    scopus 로고
    • Drug delivery methods for posterior segment disease
    • Hsu J. Drug delivery methods for posterior segment disease. Curr Opin Ophthalmol. 2007;18:235–239.
    • (2007) Curr Opin Ophthalmol , vol.18 , pp. 235-239
    • Hsu, J.1
  • 25
    • 70350148188 scopus 로고    scopus 로고
    • Nanocarriers in ocular drug delivery: an update review
    • Wadhwa S, Paliwal R, Paliwal SR, et al. Nanocarriers in ocular drug delivery:an update review. Curr Pharm Des. 2009;15:2724–2750.
    • (2009) Curr Pharm Des , vol.15 , pp. 2724-2750
    • Wadhwa, S.1    Paliwal, R.2    Paliwal, S.R.3
  • 27
    • 84870709485 scopus 로고    scopus 로고
    • Ocular drug delivery: a clue from nanotechnology
    • Bucolo C, Drago F, Salomone S. Ocular drug delivery:a clue from nanotechnology. Front Pharmacol. 2012;3:2002–2004.
    • (2012) Front Pharmacol , vol.3 , pp. 2002-2004
    • Bucolo, C.1    Drago, F.2    Salomone, S.3
  • 28
    • 79952450877 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye
    • Thrimawithana TR, Young S, Bunt CR, et al. Drug delivery to the posterior segment of the eye. Drug Discov Today. 2011;16:271–277.
    • (2011) Drug Discov Today , vol.16 , pp. 271-277
    • Thrimawithana, T.R.1    Young, S.2    Bunt, C.R.3
  • 29
    • 84874258717 scopus 로고    scopus 로고
    • Intracameral acetylcholine effectively contracts pupils after dilatation with intracameral mydriatics
    • Bäckström G, Lundberg B, Behndig A. Intracameral acetylcholine effectively contracts pupils after dilatation with intracameral mydriatics. Acta Ophthalmol. 2013;91(2):123–126.
    • (2013) Acta Ophthalmol , vol.91 , Issue.2 , pp. 123-126
    • Bäckström, G.1    Lundberg, B.2    Behndig, A.3
  • 30
    • 70350148188 scopus 로고    scopus 로고
    • Nanocarriers in ocular drug delivery: an update review
    • Wadhwa S, Paliwal R, Paliwal SR, et al. Nanocarriers in ocular drug delivery:an update review. Curr Pharm Des. 2009;15:2724–2750.
    • (2009) Curr Pharm Des , vol.15 , pp. 2724-2750
    • Wadhwa, S.1    Paliwal, R.2    Paliwal, S.R.3
  • 31
    • 31544455253 scopus 로고    scopus 로고
    • Treatment of cytomegalovirus retinitis in AIDS patients with intravitreal ganciclovir
    • Ausayakhun S, Yuvaves P, Ngamtiphakom S, et al. Treatment of cytomegalovirus retinitis in AIDS patients with intravitreal ganciclovir. J Med Assoc Thai. 2005;88:S15–S20.
    • (2005) J Med Assoc Thai , vol.88 , pp. S15-S20
    • Ausayakhun, S.1    Yuvaves, P.2    Ngamtiphakom, S.3
  • 32
    • 84940187008 scopus 로고    scopus 로고
    • Novel intraocular therapy in non-infectious uveitis of the posterior segment of the eye
    • Mikhail M, Sallam A. Novel intraocular therapy in non-infectious uveitis of the posterior segment of the eye. Med Hypothesis Discov Innov Ophthalmol. 2013;2(4):113–120.
    • (2013) Med Hypothesis Discov Innov Ophthalmol , vol.2 , Issue.4 , pp. 113-120
    • Mikhail, M.1    Sallam, A.2
  • 34
    • 33751272909 scopus 로고    scopus 로고
    • Non-viral ocular gene therapy: potential ocular therapeutic avenues
    • Bloquel C, Bourges JL, Touchard E, et al. Non-viral ocular gene therapy:potential ocular therapeutic avenues. Adv Drug Deliver Rev. 2006;58:1224–1242.
    • (2006) Adv Drug Deliver Rev , vol.58 , pp. 1224-1242
    • Bloquel, C.1    Bourges, J.L.2    Touchard, E.3
  • 35
    • 79953653858 scopus 로고    scopus 로고
    • Carbon monoxide and the eye: implications for glaucoma therapy
    • Bucolo C, Drago F. Carbon monoxide and the eye:implications for glaucoma therapy. Pharmacol Ther. 2011;130(2):191–201.
    • (2011) Pharmacol Ther , vol.130 , Issue.2 , pp. 191-201
    • Bucolo, C.1    Drago, F.2
  • 36
    • 84894575360 scopus 로고    scopus 로고
    • Nanoparticles in the ocular drug delivery
    • Zhou HY, Hao JL, Wang S, et al. Nanoparticles in the ocular drug delivery. Int J Ophthalmol. 2013;6(3):390–396.
    • (2013) Int J Ophthalmol , vol.6 , Issue.3 , pp. 390-396
    • Zhou, H.Y.1    Hao, J.L.2    Wang, S.3
  • 37
    • 84873880828 scopus 로고    scopus 로고
    • Targeting herpetic keratitis by gene therapy
    • Elbadawy HM, Gailledrat M, Desseaux C, et al. Targeting herpetic keratitis by gene therapy. J Ophthalmol. 2012;2012:594869.
    • (2012) J Ophthalmol , vol.2012 , pp. 594869
    • Elbadawy, H.M.1    Gailledrat, M.2    Desseaux, C.3
  • 38
    • 84861157207 scopus 로고    scopus 로고
    • Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone
    • Cho YK, Uehara H, Young JR, et al. Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone. Invest Ophthalmol Vis Sci. 2012;53(4):2328–2336.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , Issue.4 , pp. 2328-2336
    • Cho, Y.K.1    Uehara, H.2    Young, J.R.3
  • 39
    • 84861326911 scopus 로고    scopus 로고
    • Effects of all-trans retinoic acid nanoparticles on corneal epithelial wound healing
    • Hattori M, Shimizu K, Katsumura K, et al. Effects of all-trans retinoic acid nanoparticles on corneal epithelial wound healing. Graefes Arch Clin Exp Ophthalmol. 2012;250(4):557–563.
    • (2012) Graefes Arch Clin Exp Ophthalmol , vol.250 , Issue.4 , pp. 557-563
    • Hattori, M.1    Shimizu, K.2    Katsumura, K.3
  • 40
    • 84896542786 scopus 로고    scopus 로고
    • Nanotechnology and glaucoma: a review of the potential implications of glaucoma nanomedicine
    • Kim NJ, Harris A, Gerber A, et al. Nanotechnology and glaucoma:a review of the potential implications of glaucoma nanomedicine. Br J Ophthalmol. 2014;98:427–431.
    • (2014) Br J Ophthalmol , vol.98 , pp. 427-431
    • Kim, N.J.1    Harris, A.2    Gerber, A.3
  • 41
    • 84947924261 scopus 로고    scopus 로고
    • Controversies in glaucoma: current medical treatment and drug development
    • Bucolo C, Platania CB, Reibaldi M, et al. Controversies in glaucoma:current medical treatment and drug development. Curr Pharm Des. 2015;21(32):4673–4681.
    • (2015) Curr Pharm Des , vol.21 , Issue.32 , pp. 4673-4681
    • Bucolo, C.1    Platania, C.B.2    Reibaldi, M.3
  • 42
    • 84871307452 scopus 로고    scopus 로고
    • Pharmacological management of ocular hypertension: current approaches and future prospective
    • Bucolo C, Salomone S, Drago F, et al. Pharmacological management of ocular hypertension:current approaches and future prospective. Curr Opin Pharmacol. 2013;13(1):50–55.
    • (2013) Curr Opin Pharmacol , vol.13 , Issue.1 , pp. 50-55
    • Bucolo, C.1    Salomone, S.2    Drago, F.3
  • 43
    • 84872330873 scopus 로고    scopus 로고
    • Polymeric nanoparticles augment the ocular hypotensive effect of melatonin in Rabbits
    • Musumeci T, Bucolo C, Carbone C, et al. Polymeric nanoparticles augment the ocular hypotensive effect of melatonin in Rabbits. Int J Pharm. 2013;440(2):135–140.
    • (2013) Int J Pharm , vol.440 , Issue.2 , pp. 135-140
    • Musumeci, T.1    Bucolo, C.2    Carbone, C.3
  • 44
    • 82255180746 scopus 로고    scopus 로고
    • Nanotechnology and nanotoxicology in retinopathy
    • Jo DH, Lee TG, Kim JH. Nanotechnology and nanotoxicology in retinopathy. Int J Mol Sci. 2011;12:8288–8301.
    • (2011) Int J Mol Sci , vol.12 , pp. 8288-8301
    • Jo, D.H.1    Lee, T.G.2    Kim, J.H.3
  • 45
    • 84911493996 scopus 로고    scopus 로고
    • Nanocarriers for ocular delivery for possible benefits in the treatment of anterior uveitis: focus on current paradigms and future directions
    • Preeti K, Suresh M, Abhishek K. Nanocarriers for ocular delivery for possible benefits in the treatment of anterior uveitis:focus on current paradigms and future directions. Expert Opin Drug Deliv. 2014;11(11):1747–1768.
    • (2014) Expert Opin Drug Deliv , vol.11 , Issue.11 , pp. 1747-1768
    • Preeti, K.1    Suresh, M.2    Abhishek, K.3
  • 46
    • 0026772610 scopus 로고
    • Ocular effects of topical and systemic steroids
    • Renfro L, Snow JS. Ocular effects of topical and systemic steroids. Dermatol Clin. 1992;10:505–512.
    • (1992) Dermatol Clin , vol.10 , pp. 505-512
    • Renfro, L.1    Snow, J.S.2
  • 47
    • 0037280734 scopus 로고    scopus 로고
    • Topical nonsteroidal anti-inflammatory therapy in ophthalmology
    • Schalnus R. Topical nonsteroidal anti-inflammatory therapy in ophthalmology. Ophthalmologica. 2003;217:89–98.
    • (2003) Ophthalmologica , vol.217 , pp. 89-98
    • Schalnus, R.1
  • 48
    • 84934275924 scopus 로고    scopus 로고
    • Recent trends: medical management of infectious keratitis
    • Solanki S, Rathi M, Khanduja S, et al. Recent trends:medical management of infectious keratitis. Oman J Ophthalmol. 2015;8(2):83–85.
    • (2015) Oman J Ophthalmol , vol.8 , Issue.2 , pp. 83-85
    • Solanki, S.1    Rathi, M.2    Khanduja, S.3
  • 49
    • 84867996045 scopus 로고    scopus 로고
    • The microbiology of endophthalmitis: global trends and a local perspective
    • Keynan Y, Finkelman Y, Lagacé-Wiens P. The microbiology of endophthalmitis:global trends and a local perspective. Eur J Clin Microbiol Infect Dis. 2012;31:2879–2886.
    • (2012) Eur J Clin Microbiol Infect Dis , vol.31 , pp. 2879-2886
    • Keynan, Y.1    Finkelman, Y.2    Lagacé-Wiens, P.3
  • 50
    • 0023735936 scopus 로고
    • Studies on corneal permeability and an evaluation of prostaglandin F(2α) pro-drugs and sodium hyaluronate
    • Camber O. Studies on corneal permeability and an evaluation of prostaglandin F(2α) pro-drugs and sodium hyaluronate. Acta Pharm Suec. 1988;25(3):181.
    • (1988) Acta Pharm Suec , vol.25 , Issue.3 , pp. 181
    • Camber, O.1
  • 51
    • 79955103902 scopus 로고    scopus 로고
    • Corneal cell culture models: a tool to study corneal drug absorption
    • Surajit D. Corneal cell culture models:a tool to study corneal drug absorption. Expert Opin Drug Metab Toxicol. 2011;7(5):529–532.
    • (2011) Expert Opin Drug Metab Toxicol , vol.7 , Issue.5 , pp. 529-532
    • Surajit, D.1
  • 53
    • 38349175746 scopus 로고    scopus 로고
    • Alternative methods for eye and skin irritation tests: an overview
    • Vinardell MP, Mitjans M. Alternative methods for eye and skin irritation tests:an overview. J Pharm Sci. 2008;97:46–59.
    • (2008) J Pharm Sci , vol.97 , pp. 46-59
    • Vinardell, M.P.1    Mitjans, M.2
  • 54
    • 77952308201 scopus 로고    scopus 로고
    • Retinal and ocular toxicity in ocular application of drugs and chemicals–part I: animal models and toxicity assays
    • Marcondes PF, Rodrigues EB, Maia M. Retinal and ocular toxicity in ocular application of drugs and chemicals–part I:animal models and toxicity assays. Ophthalmic Res. 2010;44:82–104.
    • (2010) Ophthalmic Res , vol.44 , pp. 82-104
    • Marcondes, P.F.1    Rodrigues, E.B.2    Maia, M.3
  • 55
    • 78650222440 scopus 로고    scopus 로고
    • Animal models of choroidal and retinal neovascularization
    • Grossniklaus HE, Kang SJ, Berglin L. Animal models of choroidal and retinal neovascularization. Prog Retin Eye Res. 2010;29:500–519.
    • (2010) Prog Retin Eye Res , vol.29 , pp. 500-519
    • Grossniklaus, H.E.1    Kang, S.J.2    Berglin, L.3
  • 56
    • 18344370953 scopus 로고    scopus 로고
    • Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure
    • Weber BH, Schrewe H, Molday LL, et al. Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure. Proc Natl Acad Sci USA. 2002;99:6222–6227.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6222-6227
    • Weber, B.H.1
  • 57
    • 84922507236 scopus 로고    scopus 로고
    • Biology and therapy of inherited retinal degenerative disease: insights from mouse models
    • Veleri S, Lazar CH, Chang B, et al. Biology and therapy of inherited retinal degenerative disease:insights from mouse models. Dis Model Mech. 2015;8:109–129.
    • (2015) Dis Model Mech , vol.8 , pp. 109-129
    • Veleri, S.1    Lazar, C.H.2    Chang, B.3
  • 58
    • 84877782648 scopus 로고    scopus 로고
    • RPE65 gene therapy slows cone loss in Rpe65-deficient dogs
    • Mowat FM, Breuwer AR, Bartoe JT, et al. RPE65 gene therapy slows cone loss in Rpe65-deficient dogs. Gene Ther. 2013;20(5):545–555.
    • (2013) Gene Ther , vol.20 , Issue.5 , pp. 545-555
    • Mowat, F.M.1    Breuwer, A.R.2    Bartoe, J.T.3
  • 59
    • 77955621380 scopus 로고    scopus 로고
    • Animal models and different therapies for treatment of retinitis pigmentosa
    • Rivas MA, Vecino E. Animal models and different therapies for treatment of retinitis pigmentosa. Histol Histopathol. 2009;24(10):1295–1322.
    • (2009) Histol Histopathol , vol.24 , Issue.10 , pp. 1295-1322
    • Rivas, M.A.1    Vecino, E.2
  • 60
    • 84926394128 scopus 로고    scopus 로고
    • Recent patents on ophthalmic nanoformulations and therapeutic implications
    • Ako-Adounvo AM, Nagarwal RC, Oliveira L, et al. Recent patents on ophthalmic nanoformulations and therapeutic implications. Recent Pat Drug Deliv Formul. 2014;8:193–201.
    • (2014) Recent Pat Drug Deliv Formul , vol.8 , pp. 193-201
    • Ako-Adounvo, A.M.1    Nagarwal, R.C.2    Oliveira, L.3
  • 61
    • 84904559612 scopus 로고    scopus 로고
    • Applications of polymeric and lipid nanoparticles in ophthalmic pharmaceutical formulations: present and future considerations
    • Almeida H, Amaral MH, Lobão P, et al. Applications of polymeric and lipid nanoparticles in ophthalmic pharmaceutical formulations:present and future considerations. J Pharm Pharm Sci. 2014;17(3):278–293.• Compares lipid and polymeric nanoparticles for ocular delivery.
    • (2014) J Pharm Pharm Sci , vol.17 , Issue.3 , pp. 278-293
    • Almeida, H.1    Amaral, M.H.2    Lobão, P.3
  • 62
    • 85019233004 scopus 로고    scopus 로고
    • Microparticles and nanoparticles in ocular drug delivery
    • New York (NY): Informa Healthcare
    • Kothuri MK, Pinnamaneni S, Das NG, et al. Microparticles and nanoparticles in ocular drug delivery. In:Mitra AK, editor. Ophthalmic drug delivery systems. New York (NY):Informa Healthcare; 2003. p. 437–466.
    • (2003) Ophthalmic drug delivery systems , pp. 437-466
    • Kothuri, M.K.1    Pinnamaneni, S.2    Das, N.G.3    Mitra, A.K.4
  • 63
    • 77956161610 scopus 로고    scopus 로고
    • Solid lipid nanoparticles for ocular drug delivery
    • Seyfoddin A, Shaw J, Al-Kassas R. Solid lipid nanoparticles for ocular drug delivery. Drug Deliv. 2010;17:467–489.
    • (2010) Drug Deliv , vol.17 , pp. 467-489
    • Seyfoddin, A.1    Shaw, J.2    Al-Kassas, R.3
  • 64
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: production, characterization and applications
    • Mehnert W, Mäder K. Solid lipid nanoparticles:production, characterization and applications. Adv Drug Deliv Rev. 2001;47:165–196.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 165-196
    • Mehnert, W.1    Mäder, K.2
  • 65
    • 84859950305 scopus 로고    scopus 로고
    • Lipid nanoparticles: state of the art, new preparation methods and challenges in drug delivery
    • Battaglia L, Gallarate M. Lipid nanoparticles:state of the art, new preparation methods and challenges in drug delivery. Expert Opin Drug Deliv. 2012;9(5):497–508.•• Describes new formulative approaches and trends in SLN field.
    • (2012) Expert Opin Drug Deliv , vol.9 , Issue.5 , pp. 497-508
    • Battaglia, L.1    Gallarate, M.2
  • 67
    • 0037093721 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin
    • Cavalli R, Gasco MR, Chetoni P, et al. Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin. Int J Pharm. 2002;238:241–245.
    • (2002) Int J Pharm , vol.238 , pp. 241-245
    • Cavalli, R.1    Gasco, M.R.2    Chetoni, P.3
  • 68
    • 84862833261 scopus 로고    scopus 로고
    • Development and optimization of solid lipid nanoparticle formulation for ophthalmic delivery of chloramphenicol using a box-behnken design
    • JHao J, Fang X, Zhou Y, et al. Development and optimization of solid lipid nanoparticle formulation for ophthalmic delivery of chloramphenicol using a box-behnken design. Int J Nanomedicine. 2011;6:683–692.
    • (2011) Int J Nanomedicine , vol.6 , pp. 683-692
    • JHao, J.1    Fang, X.2    Zhou, Y.3
  • 69
    • 84876297984 scopus 로고    scopus 로고
    • Part I: development and optimization of solid-lipid nanoparticles using box-behnken statistical design for ocular delivery of gatifloxacin
    • Kalam MA, Sultana Y, Ali A, et al. Part I:development and optimization of solid-lipid nanoparticles using box-behnken statistical design for ocular delivery of gatifloxacin. J Biomed Mater Res A. 2013;101A 6:1813–1827.
    • (2013) J Biomed Mater Res A , vol.101A6 , pp. 1813-1827
    • Kalam, M.A.1    Sultana, Y.2    Ali, A.3
  • 70
    • 84876285264 scopus 로고    scopus 로고
    • Part II: enhancement of transcorneal delivery of gatifloxacin by solid lipid nanoparticles in comparison to commercial aqueous eye drops
    • Kalam MA, Sultana Y, Ali A, et al. Part II:enhancement of transcorneal delivery of gatifloxacin by solid lipid nanoparticles in comparison to commercial aqueous eye drops. J Biomed Mater Res A. 2013;101A(6:1828–1836.
    • (2013) J Biomed Mater Res A , vol.101A6 , pp. 1828-1836
    • Kalam, M.A.1    Sultana, Y.2    Ali, A.3
  • 71
    • 77949419485 scopus 로고    scopus 로고
    • Preparation, characterization, and evaluation of gatifloxacin loaded solid lipid nanoparticles as colloidal ocular drug delivery system
    • Kalam MA, Sultana Y, Ali A, et al. Preparation, characterization, and evaluation of gatifloxacin loaded solid lipid nanoparticles as colloidal ocular drug delivery system. J Drug Targ. 2010;18(3):191–204.
    • (2010) J Drug Targ , vol.18 , Issue.3 , pp. 191-204
    • Kalam, M.A.1    Sultana, Y.2    Ali, A.3
  • 72
    • 84953312653 scopus 로고    scopus 로고
    • Application of box–behnken design for preparation of levofloxacin-loaded stearic acid solid lipid nanoparticles for ocular delivery : optimization, in vitro release, ocular tolerance, and antibacterial activity
    • Salman M, Ahad A, Aslam M, et al. Application of box–behnken design for preparation of levofloxacin-loaded stearic acid solid lipid nanoparticles for ocular delivery:optimization, in vitro release, ocular tolerance, and antibacterial activity. Int J Biol Macromolec. 2016;85:258–270.
    • (2016) Int J Biol Macromolec , vol.85 , pp. 258-270
    • Salman, M.1    Ahad, A.2    Aslam, M.3
  • 73
    • 84929406416 scopus 로고    scopus 로고
    • Development and characterization of itraconazole loaded solid lipid nanoparticles for ocular delivery
    • Mohanty B, Majumdar D, Mishra S, et al. Development and characterization of itraconazole loaded solid lipid nanoparticles for ocular delivery. Pharm Dev Technol. 2015;20(4):458–464.
    • (2015) Pharm Dev Technol , vol.20 , Issue.4 , pp. 458-464
    • Mohanty, B.1    Majumdar, D.2    Mishra, S.3
  • 74
    • 84940975899 scopus 로고    scopus 로고
    • Lipid-polyethylene glycol based nano-ocular formulation of ketoconazole
    • Kakkar S, Karuppayil SM, Raut JS, et al. Lipid-polyethylene glycol based nano-ocular formulation of ketoconazole. Int J Pharm. 2015;495(1):276–289.
    • (2015) Int J Pharm , vol.495 , Issue.1 , pp. 276-289
    • Kakkar, S.1    Karuppayil, S.M.2    Raut, J.S.3
  • 75
    • 84874502028 scopus 로고    scopus 로고
    • Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir
    • Seyfoddin A, Al-Kassas R. Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir. Drug Dev Ind Pharm. 2013;39(4):508–519.
    • (2013) Drug Dev Ind Pharm , vol.39 , Issue.4 , pp. 508-519
    • Seyfoddin, A.1    Al-Kassas, R.2
  • 76
    • 41349106751 scopus 로고    scopus 로고
    • Diclofenac sodium delivery to the eye: in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct
    • Attama AA, Reichl S, Muller-Goymann CC. Diclofenac sodium delivery to the eye:in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct. Int J Pharm. 2008;355:307–313.
    • (2008) Int J Pharm , vol.355 , pp. 307-313
    • Attama, A.A.1    Reichl, S.2    Muller-Goymann, C.C.3
  • 77
    • 51649130848 scopus 로고    scopus 로고
    • A controlled-release ocular delivery system for ibuprofen based on nanostructured lipid carriers
    • Xiang L, Nie S-F, Kong J, et al. A controlled-release ocular delivery system for ibuprofen based on nanostructured lipid carriers. Int J Pharm. 2008;363:177–182.
    • (2008) Int J Pharm , vol.363 , pp. 177-182
    • Xiang, L.1    Nie, S.-F.2    Kong, J.3
  • 78
    • 77956650644 scopus 로고    scopus 로고
    • Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC
    • Gonzalez-Mira E, Egea MA, Garcia ML, et al. Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. Colloids Surf B Biointerfaces. 2010;81:412–421.
    • (2010) Colloids Surf B Biointerfaces , vol.81 , pp. 412-421
    • Gonzalez-Mira, E.1    Egea, M.A.2    Garcia, M.L.3
  • 79
    • 78650178421 scopus 로고    scopus 로고
    • Nanostructured lipid carrier (NLC) coated with chitosan oligosaccharides and its potential use in ocular drug delivery system
    • Qiuhua L, Junming Z, Xiangrong Z. Nanostructured lipid carrier (NLC) coated with chitosan oligosaccharides and its potential use in ocular drug delivery system. Int J Pharm. 2011;403:185–191.
    • (2011) Int J Pharm , vol.403 , pp. 185-191
    • Qiuhua, L.1    Junming, Z.2    Xiangrong, Z.3
  • 80
    • 84875034773 scopus 로고    scopus 로고
    • Indomethacin-loaded solid lipid nanoparticles for ocular delivery: development, characterization, and in vitro evaluation
    • Hippalgaonkar K, Adelli GR, Hippalgaonkar K, et al. Indomethacin-loaded solid lipid nanoparticles for ocular delivery:development, characterization, and in vitro evaluation. J Ocul Pharmacol Ther. 2013;29(2):216–228.
    • (2013) J Ocul Pharmacol Ther , vol.29 , Issue.2 , pp. 216-228
    • Hippalgaonkar, K.1    Adelli, G.R.2    Hippalgaonkar, K.3
  • 81
    • 77953356716 scopus 로고    scopus 로고
    • Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications
    • Araújo J, Gonzalez-Mira E, Egea MA, et al. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. Int J Pharm. 2010;393:167–175.
    • (2010) Int J Pharm , vol.393 , pp. 167-175
    • Araújo, J.1    Gonzalez-Mira, E.2    Egea, M.A.3
  • 82
    • 80052103054 scopus 로고    scopus 로고
    • Nanostructured lipid carriers for triamcinolone acetonide delivery to the posterior segment of the eye
    • Araujo J, Nikoli S, Egea MA, et al. Nanostructured lipid carriers for triamcinolone acetonide delivery to the posterior segment of the eye. Colloids Surf B Biointerfaces. 2011;88:150–157.
    • (2011) Colloids Surf B Biointerfaces , vol.88 , pp. 150-157
    • Araujo, J.1    Nikoli, S.2    Egea, M.A.3
  • 83
    • 79953234715 scopus 로고    scopus 로고
    • Preparation and evaluation of solid lipid nanoparticles of baicalin for ocular drug delivery system in vitro and in vivo
    • Liu Z, Zhang X, Haoyun W, et al. Preparation and evaluation of solid lipid nanoparticles of baicalin for ocular drug delivery system in vitro and in vivo. Drug Dev Ind Pharm. 2011;37(4):475–481.
    • (2011) Drug Dev Ind Pharm , vol.37 , Issue.4 , pp. 475-481
    • Liu, Z.1    Zhang, X.2    Haoyun, W.3
  • 84
    • 84948845076 scopus 로고    scopus 로고
    • Quercetin delivery to porcine cornea and sclera by solid lipid nanoparticles and nanoemulsion
    • Liu C-H, Huang Y-C, Jhang J-W, et al. Quercetin delivery to porcine cornea and sclera by solid lipid nanoparticles and nanoemulsion. RSC Adv. 2015;5:100923–100933.
    • (2015) RSC Adv , vol.5 , pp. 100923-100933
    • Liu, C.-H.1    Huang, Y.-C.2    Jhang, J.-W.3
  • 85
    • 84959473069 scopus 로고    scopus 로고
    • Biopharmaceutical evaluation of epigallocatechin gallate-loaded cationic lipid nanoparticles (EGCG-LNs): in vivo, in vitro and EX Vivo studies
    • Fangueiro JF, Calpena AC, Clares B, et al. Biopharmaceutical evaluation of epigallocatechin gallate-loaded cationic lipid nanoparticles (EGCG-LNs):in vivo, in vitro and EX Vivo studies. Int J Pharm. 2016;502(1–2):161–169.
    • (2016) Int J Pharm , vol.502 , Issue.1-2 , pp. 161-169
    • Fangueiro, J.F.1    Calpena, A.C.2    Clares, B.3
  • 86
    • 84938073376 scopus 로고    scopus 로고
    • Solid lipid nanoparticles for delivery of Calendula officinalis extract
    • Arana L, Salado C, Vega S, et al. Solid lipid nanoparticles for delivery of Calendula officinalis extract. Colloids Surf B Biointerfaces. 2015;135:18–26.
    • (2015) Colloids Surf B Biointerfaces , vol.135 , pp. 18-26
    • Arana, L.1    Salado, C.2    Vega, S.3
  • 87
    • 78349311591 scopus 로고    scopus 로고
    • Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: improving in vivo ocular distribution
    • Shen J, Deng Y, Jin X, et al. Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A:improving in vivo ocular distribution. Int J Pharm. 2010;402:248–253.
    • (2010) Int J Pharm , vol.402 , pp. 248-253
    • Shen, J.1    Deng, Y.2    Jin, X.3
  • 88
    • 75449109191 scopus 로고    scopus 로고
    • Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery
    • Başaran E, Demirel M, Sırmagül B, et al. Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery. J Microencapsul. 2010;27(1):37–47.
    • (2010) J Microencapsul , vol.27 , Issue.1 , pp. 37-47
    • Başaran, E.1    Demirel, M.2    Sırmagül, B.3
  • 89
    • 84859632374 scopus 로고    scopus 로고
    • Solid lipid nanoparticles prepared by coacervation method as vehicles for ocular cyclosporine
    • Battaglia L, D’Addino I, Peira E, et al. Solid lipid nanoparticles prepared by coacervation method as vehicles for ocular cyclosporine. J Drug Del Sci Tech. 2012;22(2):125–130.
    • (2012) J Drug Del Sci Tech , vol.22 , Issue.2 , pp. 125-130
    • Battaglia, L.1    D’Addino, I.2    Peira, E.3
  • 90
    • 53949111819 scopus 로고    scopus 로고
    • Cyclosporine A loaded SLNs: evaluation of cellular uptake and corneal cytotoxicity
    • Gokce EH, Sandri G, Bonferoni MC, et al. Cyclosporine A loaded SLNs:evaluation of cellular uptake and corneal cytotoxicity. Int J Pharm. 2008;364:76–86.
    • (2008) Int J Pharm , vol.364 , pp. 76-86
    • Gokce, E.H.1    Sandri, G.2    Bonferoni, M.C.3
  • 91
    • 52649146480 scopus 로고    scopus 로고
    • Preparation of CyA-loaded solid lipid nanoparticles and application on ocular preparations
    • Niu M, Shi K, Sun Y, et al. Preparation of CyA-loaded solid lipid nanoparticles and application on ocular preparations. J Drug Del Sci Tech. 2008;18(4):293–297.
    • (2008) J Drug Del Sci Tech , vol.18 , Issue.4 , pp. 293-297
    • Niu, M.1    Shi, K.2    Sun, Y.3
  • 92
    • 67649101315 scopus 로고    scopus 로고
    • Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery
    • Shen J, Wang Y, Ping Q, et al. Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery. J Control Release. 2009;137:217–223.
    • (2009) J Control Release , vol.137 , pp. 217-223
    • Shen, J.1    Wang, Y.2    Ping, Q.3
  • 93
    • 70350604541 scopus 로고    scopus 로고
    • Sustained release and permeation of timolol from surface-modified solid lipid nanoparticles through bioengineered human cornea
    • Attama AA, Reichl S, Müller-Goymann CC. Sustained release and permeation of timolol from surface-modified solid lipid nanoparticles through bioengineered human cornea. Curr Eye Res. 2009;34:698–705.
    • (2009) Curr Eye Res , vol.34 , pp. 698-705
    • Attama, A.A.1    Reichl, S.2    Müller-Goymann, C.C.3
  • 94
    • 84911463961 scopus 로고    scopus 로고
    • Methazolamide-loaded solid lipid nanoparticles modified with low-molecular weight chitosan for the treatment of glaucoma: vitro and vivo study
    • Wang F, Chen L, Zhang D, et al. Methazolamide-loaded solid lipid nanoparticles modified with low-molecular weight chitosan for the treatment of glaucoma:vitro and vivo study. J Drug Target. 2014;22(9):849–858.
    • (2014) J Drug Target , vol.22 , Issue.9 , pp. 849-858
    • Wang, F.1    Chen, L.2    Zhang, D.3
  • 95
    • 0028897685 scopus 로고
    • Preparation and evaluation in vitro of colloidal lipospheres containing pilocarpine as ion pair
    • Cavalli R, Morel S, Gasco MR, et al. Preparation and evaluation in vitro of colloidal lipospheres containing pilocarpine as ion pair. Int J Pharm. 1995;117:243–246.
    • (1995) Int J Pharm , vol.117 , pp. 243-246
    • Cavalli, R.1    Morel, S.2    Gasco, M.R.3
  • 96
    • 84911874105 scopus 로고    scopus 로고
    • Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in Rabbit
    • Leonardi A, Bucolo C, Drago F, et al. Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in Rabbit. Int J Pharm. 2015;478(1):180–186.
    • (2015) Int J Pharm , vol.478 , Issue.1 , pp. 180-186
    • Leonardi, A.1    Bucolo, C.2    Drago, F.3
  • 97
    • 84949556196 scopus 로고    scopus 로고
    • Effect of sterilization on the physical stability of brimonidine-loaded solid lipid nanoparticles and nanostructured lipid carriers
    • El-Salamouni NS, Farid RM, El-Kamel AH, et al. Effect of sterilization on the physical stability of brimonidine-loaded solid lipid nanoparticles and nanostructured lipid carriers. Int J Pharm. 2015;496(2):976–983.
    • (2015) Int J Pharm , vol.496 , Issue.2 , pp. 976-983
    • El-Salamouni, N.S.1    Farid, R.M.2    El-Kamel, A.H.3
  • 98
    • 84860112894 scopus 로고    scopus 로고
    • Dextran and protamine-based solid lipid nanoparticles as potential vectors for the treatment of X-linked juvenile retinoschisis
    • Delgado D, Del Pozo-Rodríguez A, Solinís MÁ, et al. Dextran and protamine-based solid lipid nanoparticles as potential vectors for the treatment of X-linked juvenile retinoschisis. Hum Gene Ther. 2011;23(4):345–355.
    • (2011) Hum Gene Ther , vol.23 , Issue.4 , pp. 345-355
    • Delgado, D.1    Del Pozo-Rodríguez, A.2    Solinís, M.Á.3
  • 99
    • 84897954495 scopus 로고    scopus 로고
    • A novel gene therapy vector based on hyaluronic acid and solid lipid nanoparticles for ocular diseases
    • Apaolaza PS, Delgado D, Del Pozo-Rodríguez A, et al. A novel gene therapy vector based on hyaluronic acid and solid lipid nanoparticles for ocular diseases. Int J Pharm. 2014;465:413–426.
    • (2014) Int J Pharm , vol.465 , pp. 413-426
    • Apaolaza, P.S.1    Delgado, D.2    Del Pozo-Rodríguez, A.3
  • 100
    • 84942891094 scopus 로고    scopus 로고
    • Solid lipid nanoparticle-based vectors intended for the treatment of X-linked juvenile retinoschisis by gene therapy: in vivo approaches in Rs1h-deficient mouse model
    • Apaolaza PS, Del Pozo-Rodríguez A, Torrecilla J, et al. Solid lipid nanoparticle-based vectors intended for the treatment of X-linked juvenile retinoschisis by gene therapy:in vivo approaches in Rs1h-deficient mouse model. J Control Release. 2015;217:273–283.
    • (2015) J Control Release , vol.217 , pp. 273-283
    • Apaolaza, P.S.1    Del Pozo-Rodríguez, A.2    Torrecilla, J.3
  • 101
    • 84960938004 scopus 로고    scopus 로고
    • Structural recovery of the retina in a retinoschisin-deficient mouse after gene replacement therapy by solid lipid nanoparticles
    • Apaolaza, Del Pozo-Rodríguez A, Solinís MA, et al. Structural recovery of the retina in a retinoschisin-deficient mouse after gene replacement therapy by solid lipid nanoparticles. Biomaterials. 2016;90:40–49.
    • (2016) Biomaterials , vol.90 , pp. 40-49
    • Apaolaza1    Del Pozo-Rodríguez, A.2    Solinís, M.A.3
  • 102
    • 84886867429 scopus 로고    scopus 로고
    • Fabrication of a composite system combining solid lipid nanoparticles and thermosensitive hydrogel for challenging ophthalmic drug delivery
    • Hao J, Wang X, Bi Y, et al. Fabrication of a composite system combining solid lipid nanoparticles and thermosensitive hydrogel for challenging ophthalmic drug delivery. Colloids Surf B Biointerfaces. 2014;114:111–120.
    • (2014) Colloids Surf B Biointerfaces , vol.114 , pp. 111-120
    • Hao, J.1    Wang, X.2    Bi, Y.3
  • 103
    • 84902247636 scopus 로고    scopus 로고
    • Influence of different surfactants on the technological properties and in vivo ocular tolerability of lipid nanoparticles
    • Leonardi A, Bucolo C, Romano GL, et al. Influence of different surfactants on the technological properties and in vivo ocular tolerability of lipid nanoparticles. Intl J Pharm. 2014;470:133–140.
    • (2014) Intl J Pharm , vol.470 , pp. 133-140
    • Leonardi, A.1    Bucolo, C.2    Romano, G.L.3
  • 104
    • 0242351952 scopus 로고    scopus 로고
    • Cyclosporine A delivery to the eye: a pharmaceutical challenge
    • Lallemand F, Felt-Baeyens O, Besseghir K, et al. Cyclosporine A delivery to the eye:a pharmaceutical challenge. Eur J Pharm Biopharm. 2003;56:307–318.
    • (2003) Eur J Pharm Biopharm , vol.56 , pp. 307-318
    • Lallemand, F.1    Felt-Baeyens, O.2    Besseghir, K.3
  • 105
    • 33747075399 scopus 로고    scopus 로고
    • Intravitreal triamcinolone acetonide: a change in a paradigm
    • Jonas JB. Intravitreal triamcinolone acetonide:a change in a paradigm. Ophthalmic Res. 2006;38:218–245.
    • (2006) Ophthalmic Res , vol.38 , pp. 218-245
    • Jonas, J.B.1
  • 106
    • 84875018489 scopus 로고    scopus 로고
    • Lipid nanoparticles as drug/gene delivery systems to the retina
    • Del Pozo-Rodríguez A, Delgado D, Gascón AR, et al. Lipid nanoparticles as drug/gene delivery systems to the retina. J Ocul Pharmacol Ther. 2013;29(2):173–188.•• Describes innovative application of SLN to gene delivery to retina.
    • (2013) J Ocul Pharmacol Ther , vol.29 , Issue.2 , pp. 173-188
    • Del Pozo-Rodríguez, A.1    Delgado, D.2    Gascón, A.R.3
  • 107
    • 84996541042 scopus 로고    scopus 로고
    • Guideline on the quality, non-clinical and clinical aspects of gene therapy medicinal products
    • European Medicines Agency
    • EMA. Guideline on the quality, non-clinical and clinical aspects of gene therapy medicinal products. Draft. EMA/CAT/80183/2014. London:European Medicines Agency; 2015.
    • (2015) Draft. EMA/CAT/80183/2014
  • 108
    • 44249120315 scopus 로고    scopus 로고
    • Effect of gene therapy on visual function in Leber’s congenital amaurosis
    • Bainbridge JW, Smith AJ, Barker SS, et al. Effect of gene therapy on visual function in Leber’s congenital amaurosis. N Engl J Med. 2008;358:2231–2239.
    • (2008) N Engl J Med , vol.358 , pp. 2231-2239
    • Bainbridge, J.W.1    Smith, A.J.2    Barker, S.S.3
  • 109
    • 78650093375 scopus 로고    scopus 로고
    • Molecular anthropology meets genetic medicine to treat blindness in the North African Jewish population: human gene therapy initiated in Israel
    • Banin E, Bandah-Rozenfeld D, Obolensky A, et al. Molecular anthropology meets genetic medicine to treat blindness in the North African Jewish population:human gene therapy initiated in Israel. Hum Gene Ther. 2010;21:1749–1757.
    • (2010) Hum Gene Ther , vol.21 , pp. 1749-1757
    • Banin, E.1    Bandah-Rozenfeld, D.2    Obolensky, A.3
  • 110
    • 54449085219 scopus 로고    scopus 로고
    • Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics
    • Cideciyan AV, Aleman TS, Boye SL, et al. Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics. Proc Natl Acad Sci USA. 2008;105:15112–15117.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15112-15117
    • Cideciyan, A.V.1    Aleman, T.S.2    Boye, S.L.3
  • 111
    • 44249085878 scopus 로고    scopus 로고
    • Safety and efficacy of gene transfer for Leber’s congenital amaurosis
    • Maguire AM, Simonelli F, Pierce EA, et al. Safety and efficacy of gene transfer for Leber’s congenital amaurosis. N Engl J Med. 2008;358:2240–2248.
    • (2008) N Engl J Med , vol.358 , pp. 2240-2248
    • Maguire, A.M.1    Simonelli, F.2    Pierce, E.A.3
  • 112
    • 46749091189 scopus 로고    scopus 로고
    • Barriers for retinal gene therapy: separating fact from fiction
    • Kumar-Singh R. Barriers for retinal gene therapy:separating fact from fiction. Vis Res. 2008;48:1671–1680.
    • (2008) Vis Res , vol.48 , pp. 1671-1680
    • Kumar-Singh, R.1
  • 113
    • 19944430177 scopus 로고    scopus 로고
    • Biodistribution of rAAV vectors following intraocular administration: evidence for the presence and persistence of vector DNA in the optic nerve and in the brain
    • Provost N, Le Meur G, Weber M, et al. Biodistribution of rAAV vectors following intraocular administration:evidence for the presence and persistence of vector DNA in the optic nerve and in the brain. Mol Ther. 2005;11:275–283.
    • (2005) Mol Ther , vol.11 , pp. 275-283
    • Provost, N.1    Le Meur, G.2    Weber, M.3
  • 114
    • 38749097725 scopus 로고    scopus 로고
    • Nanoparticle applications in ocular gene therapy
    • Cai X, Conley S, Naash M. Nanoparticle applications in ocular gene therapy. Vision Res. 2008;48:319–324.
    • (2008) Vision Res , vol.48 , pp. 319-324
    • Cai, X.1    Conley, S.2    Naash, M.3
  • 117
    • 84866737577 scopus 로고    scopus 로고
    • Improvement of drug safety by the use of lipid-based nanocarriers
    • Lim SB, Banerjee A, Önyüksel H. Improvement of drug safety by the use of lipid-based nanocarriers. J Control Release. 2012;163:34–45.
    • (2012) J Control Release , vol.163 , pp. 34-45
    • Lim, S.B.1    Banerjee, A.2    Önyüksel, H.3
  • 118
    • 84952942293 scopus 로고    scopus 로고
    • Nanostructured lipid carriers: promising drug delivery systems for future clinics
    • Beloqui A, Má S, Rodríguez-Gascón A, et al. Nanostructured lipid carriers:promising drug delivery systems for future clinics. Nanomed. 2016;12:143–161.
    • (2016) Nanomed , vol.12 , pp. 143-161
    • Beloqui, A.1    Má, S.2    Rodríguez-Gascón, A.3
  • 119
    • 84857057212 scopus 로고    scopus 로고
    • Liposomes: a new non-pharmacological therapy concept for seasonal-allergic-rhinoconjunctivitis
    • Böhm M, Avgitidou G, El Hassan E, et al. Liposomes:a new non-pharmacological therapy concept for seasonal-allergic-rhinoconjunctivitis. Eur Arch Otorhinolaryngol. 2012;269:495–502.
    • (2012) Eur Arch Otorhinolaryngol , vol.269 , pp. 495-502
    • Böhm, M.1    Avgitidou, G.2    El Hassan, E.3
  • 120
    • 84888054085 scopus 로고    scopus 로고
    • Effekt liposomaler lokaltherapie auf die Sicca-Symptomatik des primären Sjögren-Syndroms
    • Hofauer B, Bas M, Manour N, et al. Effekt liposomaler lokaltherapie auf die Sicca-Symptomatik des primären Sjögren-Syndroms. HNO. 2013;61:921–927.
    • (2013) HNO , vol.61 , pp. 921-927
    • Hofauer, B.1    Bas, M.2    Manour, N.3
  • 121
    • 0026974894 scopus 로고
    • Liposomally entrapped ganciclovir for the treatment of cytomegalovirus retinitis in AIDS patients. Experimental toxicity and pharmacokinetics, and clinical trial
    • Díaz-Llopis M, Martos MJ, España E, et al. Liposomally entrapped ganciclovir for the treatment of cytomegalovirus retinitis in AIDS patients. Experimental toxicity and pharmacokinetics, and clinical trial. Doc Ophthalmol. 1992;82:297–305.
    • (1992) Doc Ophthalmol , vol.82 , pp. 297-305
    • Díaz-Llopis, M.1    Martos, M.J.2    España, E.3
  • 122
    • 84898843847 scopus 로고    scopus 로고
    • In vivo intraocular distribution and safety of periocular nanoparticle carboplatin for treatment of advanced retinoblastoma in humans
    • Kalita D, Shome D, Jain VG, et al. In vivo intraocular distribution and safety of periocular nanoparticle carboplatin for treatment of advanced retinoblastoma in humans. Am J Ophthalmol. 2014;157:1109–1115.
    • (2014) Am J Ophthalmol , vol.157 , pp. 1109-1115
    • Kalita, D.1    Shome, D.2    Jain, V.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.