Cell-based in vitro models for predicting drug permeability

Expert Opinion on Drug Metabolism and Toxicology

Volumn 8, Issue 5, 2012, Pages 607-621

  Sarmento, Bruno ^b,c   Andrade, Fernanda ^a   Da Silva, Sara Baptista ^a   Rodrigues, Francisca ^a   Das Neves, José ^a,b   Ferreira, Domingos ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY INSTITUTE OF HEALTH SCIENCES IUCS   (Portugal)

^c INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

Author keywords

cell models; in vitro models; in vitroin vivo correlation; intestinal mucosa; permeability

Indexed keywords

CARCINOMA CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL TYPE; CELLS; CONJUNCTIVA; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG SCREENING; DRUG TRANSPORT; EPITHELIUM CELL; HUMAN; IN VITRO STUDY; INTESTINE CELL; LUNG ALVEOLUS CELL; MOLECULAR WEIGHT; NASAL CELL; NONHUMAN; OCULAR CELL; RECTAL CELL; REVIEW; SKIN CELL; VAGINAL CELL;

ANIMALS; CACO-2 CELLS; CELL LINE; CELL MEMBRANE PERMEABILITY; EYE; HUMANS; INTESTINAL ABSORPTION; INTESTINES; LUNG; MODELS, BIOLOGICAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; SKIN;

EID: 84859967380     PISSN: 17425255     EISSN: 17447607     Source Type: Journal    
DOI: 10.1517/17425255.2012.673586     Document Type: Review

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