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Volumn 81, Issue 2, 2010, Pages 412-421

Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC

Author keywords

Draize test; Eytex test; Factorial design; Flurbiprofen; Nanostructured lipid carriers (NLC); Ocular administration; Turbiscan; Ultrasounds

Indexed keywords

DRAIZE TEST; FACTORIAL DESIGN; FLURBIPROFEN; NANOSTRUCTURED LIPID CARRIERS; OCULAR ADMINISTRATION; TURBISCAN; ULTRASOUNDS;

EID: 77956650644     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2010.07.029     Document Type: Article
Times cited : (183)

References (60)
  • 1
    • 75849122316 scopus 로고    scopus 로고
    • Diagnosis and management of red eye in primary care
    • Cronau H., Kankanala R.R., Mauger T. Diagnosis and management of red eye in primary care. Am. Fam. Physician 2010, 81:137-144.
    • (2010) Am. Fam. Physician , vol.81 , pp. 137-144
    • Cronau, H.1    Kankanala, R.R.2    Mauger, T.3
  • 2
    • 0037280734 scopus 로고    scopus 로고
    • Topical non-steroidal anti-inflammatory therapy in ophthalmology
    • Schalnus R. Topical non-steroidal anti-inflammatory therapy in ophthalmology. Ophthalmologica 2003, 217:89-98.
    • (2003) Ophthalmologica , vol.217 , pp. 89-98
    • Schalnus, R.1
  • 5
    • 0030781291 scopus 로고    scopus 로고
    • Current approach to postoperative endophthalmitis
    • Sunaric-Megevand G., Pournaras C.J. Current approach to postoperative endophthalmitis. Br. J. Ophthalmol. 1997, 81:1006-1015.
    • (1997) Br. J. Ophthalmol. , vol.81 , pp. 1006-1015
    • Sunaric-Megevand, G.1    Pournaras, C.J.2
  • 6
    • 37449006316 scopus 로고    scopus 로고
    • Effect of prophylactic non-steroidal antiinflammatory drugs on cystoid macular edema assessed using optical coherence tomography quantification of total macular volume after cataract surgery
    • Almeida D.R., Johnson D., Hollands H., Smallman D., Baxter S., Eng K.T., Kratky V., ten Hove M.W., Sharma S., El-Defrawy S. Effect of prophylactic non-steroidal antiinflammatory drugs on cystoid macular edema assessed using optical coherence tomography quantification of total macular volume after cataract surgery. J. Cataract Refr. Surg. 2008, 34:64-69.
    • (2008) J. Cataract Refr. Surg. , vol.34 , pp. 64-69
    • Almeida, D.R.1    Johnson, D.2    Hollands, H.3    Smallman, D.4    Baxter, S.5    Eng, K.T.6    Kratky, V.7    ten Hove, M.W.8    Sharma, S.9    El-Defrawy, S.10
  • 8
    • 34748868594 scopus 로고    scopus 로고
    • Steroidal and non-steroidal antiinflammatory medications can improve photoreceptor survival after laser retinal photocoagulation
    • Brown J., Hacker H., Schuschereba S.T., Zwick H., Lund D.J., Stuck B.E. Steroidal and non-steroidal antiinflammatory medications can improve photoreceptor survival after laser retinal photocoagulation. Ophthalmology 2007, 114:1876-1883.
    • (2007) Ophthalmology , vol.114 , pp. 1876-1883
    • Brown, J.1    Hacker, H.2    Schuschereba, S.T.3    Zwick, H.4    Lund, D.J.5    Stuck, B.E.6
  • 10
    • 33750908033 scopus 로고    scopus 로고
    • Flurbiprofen loaded biodegradable nanoparticles for ophtalmic administration
    • Vega E., Egea M.A., Valls O., Espina M., Garcia M.L. Flurbiprofen loaded biodegradable nanoparticles for ophtalmic administration. J. Pharm. Sci. 2006, 95:2393-2405.
    • (2006) J. Pharm. Sci. , vol.95 , pp. 2393-2405
    • Vega, E.1    Egea, M.A.2    Valls, O.3    Espina, M.4    Garcia, M.L.5
  • 11
    • 75949096248 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs in ophthalmology
    • Kim S.J., Flach A.J., Jampol L.M. Nonsteroidal anti-inflammatory drugs in ophthalmology. Surv. Ophthalmol. 2010, 55:108-133.
    • (2010) Surv. Ophthalmol. , vol.55 , pp. 108-133
    • Kim, S.J.1    Flach, A.J.2    Jampol, L.M.3
  • 13
    • 0029739497 scopus 로고    scopus 로고
    • Corticosteroid therapy of eye disease. Fifty years later
    • Raizman M. Corticosteroid therapy of eye disease. Fifty years later. Arch. Ophthalmol. 1996, 114:1000-1001.
    • (1996) Arch. Ophthalmol. , vol.114 , pp. 1000-1001
    • Raizman, M.1
  • 14
    • 0036264563 scopus 로고    scopus 로고
    • Topical non-steroidal anti-inflammatory drugs for ophthalmic use: a safety review
    • Gaynes B.I., Fiscella R. Topical non-steroidal anti-inflammatory drugs for ophthalmic use: a safety review. Drug Saf. 2002, 25:233-250.
    • (2002) Drug Saf. , vol.25 , pp. 233-250
    • Gaynes, B.I.1    Fiscella, R.2
  • 15
    • 0347989502 scopus 로고    scopus 로고
    • Prednisolone and flurbiprofen drops to maintain mydriasis during phacoemulsification cataract surgery
    • Shaikh M.Y., Mars J.S., Heaven C.J. Prednisolone and flurbiprofen drops to maintain mydriasis during phacoemulsification cataract surgery. J. Cataract Refr. Surg. 2003, 29:2372-2377.
    • (2003) J. Cataract Refr. Surg. , vol.29 , pp. 2372-2377
    • Shaikh, M.Y.1    Mars, J.S.2    Heaven, C.J.3
  • 16
    • 55849151704 scopus 로고    scopus 로고
    • Recent advances and patents on solid lipid nanoparticles
    • Sawant K.K., Dodiya S.S. Recent advances and patents on solid lipid nanoparticles. Recent Path. Drug Deliv. Formul. 2008, 2:120-135.
    • (2008) Recent Path. Drug Deliv. Formul. , vol.2 , pp. 120-135
    • Sawant, K.K.1    Dodiya, S.S.2
  • 17
    • 67649101315 scopus 로고    scopus 로고
    • Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery
    • Shen J., Wang Y., Ping Q., Xiao Y., Huang X. Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery. J. Control. Release 2009, 137:217-223.
    • (2009) J. Control. Release , vol.137 , pp. 217-223
    • Shen, J.1    Wang, Y.2    Ping, Q.3    Xiao, Y.4    Huang, X.5
  • 18
    • 77953283407 scopus 로고    scopus 로고
    • Lipid nanoparticles: effect on bioavailability and pharmacokinetic changes
    • Souto E.B., Muller R.H. Lipid nanoparticles: effect on bioavailability and pharmacokinetic changes. Handb. Exp. Pharmacol. 2010, 115-141.
    • (2010) Handb. Exp. Pharmacol. , pp. 115-141
    • Souto, E.B.1    Muller, R.H.2
  • 19
    • 77956648352 scopus 로고    scopus 로고
    • Arzneistoffträger aus festen Lipidteilchen - Feste Lipid Nanosphären (SLN), European Patent 0605497
    • R.H. Müller, J. Lucks, Arzneistoffträger aus festen Lipidteilchen - Feste Lipid Nanosphären (SLN), European Patent 0605497 (1996).
    • (1996)
    • Müller, R.H.1    Lucks, J.2
  • 20
    • 36048987689 scopus 로고    scopus 로고
    • Ultrasonically controlled particle size distribution of explosives: a safe method
    • Patil M.N., Gore G.M., Pandit A.B. Ultrasonically controlled particle size distribution of explosives: a safe method. Ultrason. Sonochem 2008, 15:177-187.
    • (2008) Ultrason. Sonochem , vol.15 , pp. 177-187
    • Patil, M.N.1    Gore, G.M.2    Pandit, A.B.3
  • 21
    • 34247538000 scopus 로고    scopus 로고
    • Cavitation-a novel technique for making stable nano-suspensions
    • Patil M.N., Pandit A.B. Cavitation-a novel technique for making stable nano-suspensions. Ultrason. Sonochem. 2007, 14:519-530.
    • (2007) Ultrason. Sonochem. , vol.14 , pp. 519-530
    • Patil, M.N.1    Pandit, A.B.2
  • 22
    • 44649174310 scopus 로고    scopus 로고
    • Incorporation of peptides in phospholipid aggregates using ultrasound
    • Silva R., Little C., Ferreira H., Cavaco-Paulo A. Incorporation of peptides in phospholipid aggregates using ultrasound. Ultrason. Sonochem. 2008, 15:1026-1032.
    • (2008) Ultrason. Sonochem. , vol.15 , pp. 1026-1032
    • Silva, R.1    Little, C.2    Ferreira, H.3    Cavaco-Paulo, A.4
  • 23
    • 67349194262 scopus 로고    scopus 로고
    • Effect of polymer viscosity on physico-chemical properties and ocular tolerance of FB-loaded PLGA nanospheres
    • Araujo J., Vega E., Lopes C., Egea M.A., Garcia M.L., Souto E.B. Effect of polymer viscosity on physico-chemical properties and ocular tolerance of FB-loaded PLGA nanospheres. Colloids Surf. B: Biointerfaces 2009, 72:48-56.
    • (2009) Colloids Surf. B: Biointerfaces , vol.72 , pp. 48-56
    • Araujo, J.1    Vega, E.2    Lopes, C.3    Egea, M.A.4    Garcia, M.L.5    Souto, E.B.6
  • 25
    • 53649090334 scopus 로고    scopus 로고
    • A review of analytical methods for the identification and characterization of nano delivery systems in food
    • Luykx D.M., Peters R.J., van Ruth S.M., Bouwmeester H. A review of analytical methods for the identification and characterization of nano delivery systems in food. J. Agric. Food Chem. 2008, 56:8231-8247.
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 8231-8247
    • Luykx, D.M.1    Peters, R.J.2    van Ruth, S.M.3    Bouwmeester, H.4
  • 26
    • 0000182145 scopus 로고    scopus 로고
    • Modified booth equation for the calculation of zeta potential
    • Deshiikan S.R., Papadopoulos K.D. Modified booth equation for the calculation of zeta potential. Colloid Polym. Sci. 1998, 276:117-124.
    • (1998) Colloid Polym. Sci. , vol.276 , pp. 117-124
    • Deshiikan, S.R.1    Papadopoulos, K.D.2
  • 27
    • 77953356716 scopus 로고    scopus 로고
    • Optimization and physico-chemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications
    • Araujo J., Gonzalez-Mira E., Egea M.A., Garcia M.L., Souto E.B. Optimization and physico-chemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. Int. J. Pharm. 2010, 393:167-175.
    • (2010) Int. J. Pharm. , vol.393 , pp. 167-175
    • Araujo, J.1    Gonzalez-Mira, E.2    Egea, M.A.3    Garcia, M.L.4    Souto, E.B.5
  • 28
    • 0030866983 scopus 로고    scopus 로고
    • Physico-chemical characterization of lipid nanoparticles and evaluation of their drug loading capacity and sustained release potential
    • Westesen K., Bunjes H., Koch M.H.J. Physico-chemical characterization of lipid nanoparticles and evaluation of their drug loading capacity and sustained release potential. J. Control. Release 1997, 48:223-236.
    • (1997) J. Control. Release , vol.48 , pp. 223-236
    • Westesen, K.1    Bunjes, H.2    Koch, M.H.J.3
  • 29
    • 67349084376 scopus 로고    scopus 로고
    • Polymeric nanoparticulate system: a potential approach for ocular drug delivery
    • Nagarwal R.C., Kant S., Singh P.N., Maiti P., Pandit J.K. Polymeric nanoparticulate system: a potential approach for ocular drug delivery. J. Control. Release 2009, 136:2-13.
    • (2009) J. Control. Release , vol.136 , pp. 2-13
    • Nagarwal, R.C.1    Kant, S.2    Singh, P.N.3    Maiti, P.4    Pandit, J.K.5
  • 30
    • 0027078050 scopus 로고
    • Utilization of biomacromolecular in vitro assay systems in the prediction of in vivo toxic responses
    • Gordon V.C. Utilization of biomacromolecular in vitro assay systems in the prediction of in vivo toxic responses. Lens Eye Toxic. Res. 1992, 9:211-227.
    • (1992) Lens Eye Toxic. Res. , vol.9 , pp. 211-227
    • Gordon, V.C.1
  • 31
    • 0025076890 scopus 로고
    • An in vitro method for estimating ocular irritation
    • Soto R.J., Gordon V.C. An in vitro method for estimating ocular irritation. Toxicol. Vitro 1990, 4:332-335.
    • (1990) Toxicol. Vitro , vol.4 , pp. 332-335
    • Soto, R.J.1    Gordon, V.C.2
  • 32
    • 0028103001 scopus 로고
    • Acceptance of in vitro studies by regulatory authorities
    • Fielder R.J. Acceptance of in vitro studies by regulatory authorities. Toxicol. Vitro 1994, 8:911-916.
    • (1994) Toxicol. Vitro , vol.8 , pp. 911-916
    • Fielder, R.J.1
  • 33
    • 0017175267 scopus 로고
    • Irritant power of the principle chlorinated aliphatic solvents on the skin and ocular mucosa of the rabbit
    • Duprat P., Delsaut L., Gradiski D. Irritant power of the principle chlorinated aliphatic solvents on the skin and ocular mucosa of the rabbit. Eur. J. Toxicol. Environ. Hyg. 1976, 9:171-177.
    • (1976) Eur. J. Toxicol. Environ. Hyg. , vol.9 , pp. 171-177
    • Duprat, P.1    Delsaut, L.2    Gradiski, D.3
  • 34
    • 0000160117 scopus 로고
    • Interpretation of eye irritation tests
    • Kay J.H., Calandra J.C. Interpretation of eye irritation tests. J. Soc. Cosmet. Chem. 1962, 13:281-289.
    • (1962) J. Soc. Cosmet. Chem. , vol.13 , pp. 281-289
    • Kay, J.H.1    Calandra, J.C.2
  • 35
    • 55349118143 scopus 로고    scopus 로고
    • Application of the 3Rs principles for animals used for experiments at the beginning of the 21st century
    • Passantino A. Application of the 3Rs principles for animals used for experiments at the beginning of the 21st century. Ann. Rev. Biomed. Sci. 2008, 10:27-32.
    • (2008) Ann. Rev. Biomed. Sci. , vol.10 , pp. 27-32
    • Passantino, A.1
  • 37
    • 0343618485 scopus 로고    scopus 로고
    • Characterisation of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids
    • Jenning V., Thunemann A.F., Gohla S.H. Characterisation of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids. Int. J. Pharm. 2000, 199:167-177.
    • (2000) Int. J. Pharm. , vol.199 , pp. 167-177
    • Jenning, V.1    Thunemann, A.F.2    Gohla, S.H.3
  • 38
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: production, characterization and applications
    • Mehnert W., Mader K. Solid lipid nanoparticles: production, characterization and applications. Adv. Drug Deliv. Rev. 2001, 47:165-196.
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 165-196
    • Mehnert, W.1    Mader, K.2
  • 39
    • 77954817946 scopus 로고    scopus 로고
    • Development and statistical optimization of solid lipid nanoparticles of simvastatin by using 2(3) full factorial design
    • Shah M., Pathak K. Development and statistical optimization of solid lipid nanoparticles of simvastatin by using 2(3) full factorial design. AAPS Pharm. Sci. Tech. 2010, 11:489-496.
    • (2010) AAPS Pharm. Sci. Tech. , vol.11 , pp. 489-496
    • Shah, M.1    Pathak, K.2
  • 40
    • 77951710606 scopus 로고    scopus 로고
    • Formulation and evaluation of solid lipid nanoparticles of a water soluble drug: zidovudine
    • Singh S., Dobhal A.K., Jain A., Pandit J.K., Chakraborty S. Formulation and evaluation of solid lipid nanoparticles of a water soluble drug: zidovudine. Chem. Pharm. Bull. (Tokyo) 2010, 58:650-655.
    • (2010) Chem. Pharm. Bull. (Tokyo) , vol.58 , pp. 650-655
    • Singh, S.1    Dobhal, A.K.2    Jain, A.3    Pandit, J.K.4    Chakraborty, S.5
  • 42
    • 0029347475 scopus 로고
    • Microspheres and nanoparticles used in ocular delivery systems
    • Zimmer A., Kreuter J. Microspheres and nanoparticles used in ocular delivery systems. Adv. Drug Deliv. Rev. 1995, 8:61-73.
    • (1995) Adv. Drug Deliv. Rev. , vol.8 , pp. 61-73
    • Zimmer, A.1    Kreuter, J.2
  • 43
    • 26244444984 scopus 로고    scopus 로고
    • Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system
    • Hu F.Q., Jiang S.P., Du Y.Z., Yuan H., Ye Y.Q., Zeng S. Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system. Colloids Surf. B: Biointerfaces 2005, 45:167-173.
    • (2005) Colloids Surf. B: Biointerfaces , vol.45 , pp. 167-173
    • Hu, F.Q.1    Jiang, S.P.2    Du, Y.Z.3    Yuan, H.4    Ye, Y.Q.5    Zeng, S.6
  • 45
    • 34249042347 scopus 로고    scopus 로고
    • Effect of solid lipid nanoparticles formulation compositions on their size, zeta potential and potential for in vitro pHIS-HIV-hugag transfection
    • Asasutjarit R., Lorenzen S.I., Sirivichayakul S., Ruxrungtham K., Ruktanonchai U., Ritthidej G.C. Effect of solid lipid nanoparticles formulation compositions on their size, zeta potential and potential for in vitro pHIS-HIV-hugag transfection. Pharm. Res. 2007, 24:1098-1107.
    • (2007) Pharm. Res. , vol.24 , pp. 1098-1107
    • Asasutjarit, R.1    Lorenzen, S.I.2    Sirivichayakul, S.3    Ruxrungtham, K.4    Ruktanonchai, U.5    Ritthidej, G.C.6
  • 46
    • 67049160961 scopus 로고    scopus 로고
    • The Structural Basis of the Hydrophobic Interaction
    • IOS Press,
    • Finney J.L The Structural Basis of the Hydrophobic Interaction. Hydration Process in Biology 1999, IOS Press, pp. 115-124.
    • (1999) Hydration Process in Biology , pp. 115-124
    • Finney, J.L.1
  • 47
    • 61849084577 scopus 로고    scopus 로고
    • Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies
    • Bhaskar K., Anbu J., Ravichandiran V., Venkateswarlu V., Rao Y.M. Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies. Lipids Health Dis. 2009, 8:6.
    • (2009) Lipids Health Dis. , vol.8 , pp. 6
    • Bhaskar, K.1    Anbu, J.2    Ravichandiran, V.3    Venkateswarlu, V.4    Rao, Y.M.5
  • 48
    • 1542439759 scopus 로고    scopus 로고
    • The correlation between zeta potential and mucoadhesion strength on pig vesical mucosa
    • Bogataj M, Vovk T., Kerec M., Dimnik A., Grabnar I., Mrhar A. The correlation between zeta potential and mucoadhesion strength on pig vesical mucosa. Biol. Pharm. Bull. 2003, 26:743-746.
    • (2003) Biol. Pharm. Bull. , vol.26 , pp. 743-746
    • Bogataj, M.1    Vovk, T.2    Kerec, M.3    Dimnik, A.4    Grabnar, I.5    Mrhar, A.6
  • 49
    • 2942676810 scopus 로고    scopus 로고
    • Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations
    • Souto E.B., Wissing S.A., Barbosa C.M., Muller R.H. Evaluation of the physical stability of SLN and NLC before and after incorporation into hydrogel formulations. Eur. J. Pharm. Biopharm. 2004, 58:83-90.
    • (2004) Eur. J. Pharm. Biopharm. , vol.58 , pp. 83-90
    • Souto, E.B.1    Wissing, S.A.2    Barbosa, C.M.3    Muller, R.H.4
  • 50
    • 51649130848 scopus 로고    scopus 로고
    • A controlled-release ocular delivery system for ibuprofen based on nanostructured lipid carriers
    • Li X., Nie S.F., Kong J., Li N., Ju C.Y., Pan W.S. A controlled-release ocular delivery system for ibuprofen based on nanostructured lipid carriers. Int. J. Pharm. 2008, 363:177-182.
    • (2008) Int. J. Pharm. , vol.363 , pp. 177-182
    • Li, X.1    Nie, S.F.2    Kong, J.3    Li, N.4    Ju, C.Y.5    Pan, W.S.6
  • 51
    • 0029876015 scopus 로고    scopus 로고
    • Crystallization tendency and polymorphic transitions in triglyceride nanoparticles
    • Bunjes H., Westesen K., Koch M.H.J. Crystallization tendency and polymorphic transitions in triglyceride nanoparticles. Int. J. Pharm. 1996, 129:159-173.
    • (1996) Int. J. Pharm. , vol.129 , pp. 159-173
    • Bunjes, H.1    Westesen, K.2    Koch, M.H.J.3
  • 52
    • 24944533304 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC)-structural investigations on two different carrier systems
    • Saupe A., Wissing S.A., Lenk A., Schmidt C., Muller R.H. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC)-structural investigations on two different carrier systems. Biomed. Mater. Eng. 2005, 15:393-402.
    • (2005) Biomed. Mater. Eng. , vol.15 , pp. 393-402
    • Saupe, A.1    Wissing, S.A.2    Lenk, A.3    Schmidt, C.4    Muller, R.H.5
  • 54
    • 0036153211 scopus 로고    scopus 로고
    • Medium scale production of solid lipid nanoparticles (SLN) by high pressure homogenization
    • Jenning V., Lippacher A., Gohla S.H. Medium scale production of solid lipid nanoparticles (SLN) by high pressure homogenization. J. Microencapsul. 2002, 19:1-10.
    • (2002) J. Microencapsul. , vol.19 , pp. 1-10
    • Jenning, V.1    Lippacher, A.2    Gohla, S.H.3
  • 56
    • 33646582966 scopus 로고    scopus 로고
    • Chemical stability of lipid excipients in SLN-production of test formulations, characterisation and short-term stability
    • Radomska-Soukharev A., Muller R.H. Chemical stability of lipid excipients in SLN-production of test formulations, characterisation and short-term stability. Pharmazie 2006, 61:425-430.
    • (2006) Pharmazie , vol.61 , pp. 425-430
    • Radomska-Soukharev, A.1    Muller, R.H.2
  • 57
    • 59649097447 scopus 로고    scopus 로고
    • Lipid nanoparticles for parenteral delivery of actives
    • Joshi M.D, Muller R.H. Lipid nanoparticles for parenteral delivery of actives. Eur. J. Pharm. Biopharm. 2009, 71:161-172.
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , pp. 161-172
    • Joshi, M.D.1    Muller, R.H.2
  • 58
    • 55749086377 scopus 로고    scopus 로고
    • Polyoxyethylated non-ionic surfactants and their applications in topical ocular drug delivery
    • Jiao J. Polyoxyethylated non-ionic surfactants and their applications in topical ocular drug delivery. Adv. Drug Deliv. Rev. 2008, 60:1663-1673.
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 1663-1673
    • Jiao, J.1
  • 59
    • 0019151971 scopus 로고
    • Effect of particle size on ophthalmic bioavailability of dexamethasone suspensions in rabbits
    • Schoenwald R.D., Stewart P. Effect of particle size on ophthalmic bioavailability of dexamethasone suspensions in rabbits. J. Pharm. Sci. 1980, 69:391-394.
    • (1980) J. Pharm. Sci. , vol.69 , pp. 391-394
    • Schoenwald, R.D.1    Stewart, P.2
  • 60
    • 0043170806 scopus 로고    scopus 로고
    • Assessment of diclofenac permeation with different formulations: anti-inflammatory study of a selected formula
    • Escribano E., Calpena A.C., Queralt J., Obach R., Domenech J. Assessment of diclofenac permeation with different formulations: anti-inflammatory study of a selected formula. Eur. J. Pharm. Sci. 2003, 19:203-210.
    • (2003) Eur. J. Pharm. Sci. , vol.19 , pp. 203-210
    • Escribano, E.1    Calpena, A.C.2    Queralt, J.3    Obach, R.4    Domenech, J.5


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