Structural recovery of the retina in a retinoschisin-deficient mouse after gene replacement therapy by solid lipid nanoparticles

Biomaterials

Volumn 90, Issue , 2016, Pages 40-49

  Apaolaza, P S ^a   del Pozo Rodriguez A ^a   Solinis M A ^a   Rodriguez J M ^a   Friedrich, U ^b   Torrecilla, J ^a   Weber, B H F ^b   Rodriguez Gascon A ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Dextran; Gene therapy; Hyaluronic acid; MOPS; Retinoschisis; Solid lipid nanoparticles

Indexed keywords

CELL CULTURE; DEXTRAN; DISEASE CONTROL; GENE ENCODING; GENE EXPRESSION; GENES; HYALURONIC ACID; IMAGE CODING; MAMMALS; NANOPARTICLES; OPHTHALMOLOGY; ORGANIC ACIDS; PROTEINS;

INNER NUCLEAR LAYERS; MOPS; NONVIRAL VECTORS; OUTER NUCLEAR LAYERS; RETINAL STRUCTURE; RETINOSCHISIS; SOLID LIPID NANOPARTICLE (SLN); STRUCTURAL IMPROVEMENTS;

GENE THERAPY;

DEXTRAN; HYALURONIC ACID; OPSIN; PROTAMINE; RETINOSCHISIN; SOLID LIPID NANOPARTICLE; CELL ADHESION MOLECULE; EYE PROTEIN; NANOPARTICLE; RS1 PROTEIN, HUMAN; RS1H PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE REPLACEMENT THERAPY; GENETIC TRANSFECTION; IN VITRO STUDY; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PHOTORECEPTOR; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; RETINA BIPOLAR GANGLION CELL; RETINA INNER NUCLEAR LAYER; RETINAL THICKNESS; RETINOSCHISIN DEFICIENCY; SINGLE DRUG DOSE; ANIMAL; C57BL MOUSE; CHEMISTRY; GENE DELETION; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETICS; METABOLISM; PATHOLOGY; RETINA; RETINOSCHISIS; ULTRASTRUCTURE;

ANIMALS; CELL ADHESION MOLECULES; EYE PROTEINS; GENE DELETION; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HYALURONIC ACID; MICE; MICE, INBRED C57BL; NANOPARTICLES; RETINA; RETINOSCHISIS;

EID: 84960938004     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.03.004     Document Type: Article

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