-
1
-
-
84876664386
-
Cancer-associated lysosomal changes: Friends or foes?
-
Kallunki, T., Olsen, O. D., and Jäättelä, M. (2013) Cancer-associated lysosomal changes: friends or foes? Oncogene 32, 1995-2004
-
(2013)
Oncogene
, vol.32
, pp. 1995-2004
-
-
Kallunki, T.1
Olsen, O.D.2
Jäättelä, M.3
-
2
-
-
84888798201
-
Tumor glycolysis as a target for cancer therapy: Progress and prospects
-
Ganapathy-Kanniappan, S., and Geschwind, J. F. (2013) Tumor glycolysis as a target for cancer therapy: progress and prospects. Mol. Cancer 12, 152
-
(2013)
Mol. Cancer
, vol.12
, pp. 152
-
-
Ganapathy-Kanniappan, S.1
Geschwind, J.F.2
-
3
-
-
0018656598
-
Lysosomotropic agents 1. Synthesis and cytotoxic action of lysosomotropic detergents
-
Firestone, R. A., Pisano, J. M., and Bonney, R. J. (1979) Lysosomotropic agents. 1. Synthesis and cytotoxic action of lysosomotropic detergents. J. Med. Chem. 22, 1130-1133
-
(1979)
J. Med. Chem.
, vol.22
, pp. 1130-1133
-
-
Firestone, R.A.1
Pisano, J.M.2
Bonney, R.J.3
-
4
-
-
0019949926
-
Lysosomotropic agents 4. Carbobenzoxyglycylphenylalanyl, a new protease-sensitive masking group for introduction into cells
-
Firestone, R. A., Pisano, J. M., Bailey, P. J., Sturm, A., Bonney, R. J., Wightman, P., Devlin, R., Lin, C. S., Keller, D. L., and Tway, P. C. (1982) Lysosomotropic agents. 4. Carbobenzoxyglycylphenylalanyl, a new protease-sensitive masking group for introduction into cells. J. Med. Chem. 25, 539-544
-
(1982)
J. Med. Chem.
, vol.25
, pp. 539-544
-
-
Firestone, R.A.1
Pisano, J.M.2
Bailey, P.J.3
Sturm, A.4
Bonney, R.J.5
Wightman, P.6
Devlin, R.7
Lin, C.S.8
Keller, D.L.9
Tway, P.C.10
-
5
-
-
0021069160
-
Cell killing by lysosomotropic detergents
-
Miller, D. K., Griffiths, E., Lenard, J., and Firestone, R. A. (1983) Cell killing by lysosomotropic detergents. J. Cell Biol. 97, 1841-1851
-
(1983)
J. Cell Biol.
, vol.97
, pp. 1841-1851
-
-
Miller, D.K.1
Griffiths, E.2
Lenard, J.3
Firestone, R.A.4
-
6
-
-
0023224018
-
The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole
-
Wilson, P. D., Firestone, R. A., and Lenard, J. (1987) The role of lysosomal enzymes in killing of mammalian cells by the lysosomotropic detergent N-dodecylimidazole. J. Cell Biol. 104, 1223-1229
-
(1987)
J. Cell Biol.
, vol.104
, pp. 1223-1229
-
-
Wilson, P.D.1
Firestone, R.A.2
Lenard, J.3
-
7
-
-
0024495591
-
Reduced cytotoxicity of the lysosomotropic detergent N-dodecylimidazole after differentiation of HL60 promyelocytes
-
Wilson, P. D., Hreniuk, D., and Lenard, J. (1989) Reduced cytotoxicity of the lysosomotropic detergent N-dodecylimidazole after differentiation of HL60 promyelocytes. Cancer Res. 49, 507-510
-
(1989)
Cancer Res
, vol.49
, pp. 507-510
-
-
Wilson, P.D.1
Hreniuk, D.2
Lenard, J.3
-
8
-
-
33749146320
-
Lysosomal labilization
-
Terman, A., Kurz, T., Gustafsson, B., and Brunk, U. T. (2006) Lysosomal labilization. IUBMB Life 58, 531-539
-
(2006)
IUBMB Life
, vol.58
, pp. 531-539
-
-
Terman, A.1
Kurz, T.2
Gustafsson, B.3
Brunk, U.T.4
-
9
-
-
54949137644
-
Lysosomal membrane permeabilization in cell death
-
Boya, P., and Kroemer, G. (2008) Lysosomal membrane permeabilization in cell death. Oncogene 27, 6434-6451
-
(2008)
Oncogene
, vol.27
, pp. 6434-6451
-
-
Boya, P.1
Kroemer, G.2
-
10
-
-
78149358483
-
Lysosomal-mitochondrial cross-talk during cell death
-
Repnik, U., and Turk, B. (2010) Lysosomal-mitochondrial cross-talk during cell death. Mitochondrion 10, 662-669
-
(2010)
Mitochondrion
, vol.10
, pp. 662-669
-
-
Repnik, U.1
Turk, B.2
-
11
-
-
84878643872
-
Lysosomal cell death at a glance
-
Aits, S., and Jäättelä, M. (2013) Lysosomal cell death at a glance. J. Cell Sci. 126, 1905-1912
-
(2013)
J. Cell Sci.
, vol.126
, pp. 1905-1912
-
-
Aits, S.1
Jäättelä, M.2
-
12
-
-
0027529644
-
PH dependent cytotoxicity of N-dodecylimidazole: A compound that acquires detergent properties under acidic conditions
-
Boyer, M. J., Horn, I., Firestone, R. A., Steele-Norwood, D., and Tannock, I. F. (1993) pH dependent cytotoxicity of N-dodecylimidazole: a compound that acquires detergent properties under acidic conditions. Br. J. Cancer 67, 81-87
-
(1993)
Br. J. Cancer
, vol.67
, pp. 81-87
-
-
Boyer, M.J.1
Horn, I.2
Firestone, R.A.3
Steele-Norwood, D.4
Tannock, I.F.5
-
13
-
-
77951235938
-
Cytotoxicity, radiosensitization, and chemosensitization of tumor cells by 2-deoxy-D-glucose in vitro
-
Dwarakanath, B. S. (2009) Cytotoxicity, radiosensitization, and chemosensitization of tumor cells by 2-deoxy-D-glucose in vitro. J. Cancer Res. Ther. 5, S27-S31
-
(2009)
J. Cancer Res. Ther.
, vol.5
, pp. S27-S31
-
-
Dwarakanath, B.S.1
-
14
-
-
84908220531
-
2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy
-
Zhang, D., Li, J., Wang, F., Hu, J., Wang, S., and Sun, Y. (2014) 2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy. Cancer Lett. 355, 176-183
-
(2014)
Cancer Lett.
, vol.355
, pp. 176-183
-
-
Zhang, D.1
Li, J.2
Wang, F.3
Hu, J.4
Wang, S.5
Sun, Y.6
-
15
-
-
84861696528
-
2-Deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines
-
Zagorodna, O., Martin, S. M., Rutkowski, D. T., Kuwana, T., Spitz, D. R., and Knudson, C. M. (2012) 2-Deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines. Oncogene 31, 2738-2749
-
(2012)
Oncogene
, vol.31
, pp. 2738-2749
-
-
Zagorodna, O.1
Martin, S.M.2
Rutkowski, D.T.3
Kuwana, T.4
Spitz, D.R.5
Knudson, C.M.6
-
16
-
-
84886883442
-
Glucose-starved cells do not engage in prosurvival autophagy
-
Ramírez-Peinado, S., León-Annicchiarico, C. L., Galindo-Moreno, J., Iurlaro, R., Caro-Maldonado, A., Prehn, J. H., Ryan, K. M., and Muñoz-Pinedo, C. (2013) Glucose-starved cells do not engage in prosurvival autophagy. J. Biol. Chem. 288, 30387-30398
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 30387-30398
-
-
Ramírez-Peinado, S.1
León-Annicchiarico, C.L.2
Galindo-Moreno, J.3
Iurlaro, R.4
Caro-Maldonado, A.5
Prehn, J.H.6
Ryan, K.M.7
Muñoz-Pinedo, C.8
-
17
-
-
36749078674
-
Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation
-
Kurtoglu, M., Gao, N., Shang, J., Maher, J. C., Lehrman, M. A., Wangpaichitr, M., Savaraj, N., Lane, A. N., and Lampidis, T. J. (2007) Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation. Mol. Cancer Ther. 6, 3049-3058
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 3049-3058
-
-
Kurtoglu, M.1
Gao, N.2
Shang, J.3
Maher, J.C.4
Lehrman, M.A.5
Wangpaichitr, M.6
Savaraj, N.7
Lane, A.N.8
Lampidis, T.J.9
-
18
-
-
0031796023
-
2-deoxy-Dglucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis
-
Bell, S. E., Quinn, D. M., Kellett, G. L., and Warr, J. R. (1998) 2-deoxy-Dglucose preferentially kills multidrug-resistant human KB carcinoma cell lines by apoptosis. Br. J. Cancer 78, 1464-1470
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1464-1470
-
-
Bell, S.E.1
Quinn, D.M.2
Kellett, G.L.3
Warr, J.R.4
-
19
-
-
1642494855
-
2-deoxy-Dglucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo
-
Maschek, G., Savaraj, N., Priebe, W., Braunschweiger, P., Hamilton, K., Tidmarsh, G. F., De Young, L. R., and Lampidis, T. J. (2004) 2-deoxy-Dglucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. Cancer Res. 64, 31-34
-
(2004)
Cancer Res.
, vol.64
, pp. 31-34
-
-
Maschek, G.1
Savaraj, N.2
Priebe, W.3
Braunschweiger, P.4
Hamilton, K.5
Tidmarsh, G.F.6
De Young, L.R.7
Lampidis, T.J.8
-
20
-
-
84861158967
-
Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death
-
Cheng, G., Zielonka, J., Dranka, B. P., McAllister, D., Mackinnon, A. C., Jr, Joseph, J., and Kalyanaraman, B. (2012) Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death. Cancer Res. 72, 2634-2644
-
(2012)
Cancer Res.
, vol.72
, pp. 2634-2644
-
-
Cheng, G.1
Zielonka, J.2
Dranka, B.P.3
McAllister, D.4
Mackinnon, C.A.5
Joseph, J.6
Kalyanaraman, B.7
-
21
-
-
83355163333
-
Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models
-
Cheong, J. H., Park, E. S., Liang, J., Dennison, J. B., Tsavachidou, D., Nguyen-Charles, C., Wa Cheng, K., Hall, H., Zhang, D., Lu, Y., Ravoori, M., Kundra, V., Ajani, J., Lee, J. S., Ki Hong, W., and Mills, G. B. (2011) Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models. Mol. Cancer Ther. 10, 2350-2362
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 2350-2362
-
-
Cheong, J.H.1
Park, E.S.2
Liang, J.3
Dennison, J.B.4
Tsavachidou, D.5
Nguyen-Charles, C.6
Wa Cheng, K.7
Hall, H.8
Zhang, D.9
Lu, Y.10
Ravoori, M.11
Kundra, V.12
Ajani, J.13
Lee, J.S.14
Ki Hong, W.15
Mills, G.B.16
-
22
-
-
0030009250
-
Improving cancer radiotherapy with 2-deoxy-D-glucose: Phase I/II clinical trials on human cerebral gliomas
-
Mohanti, B. K., Rath, G. K., Anantha, N., Kannan, V., Das, B. S., Chandramouli, B. A., Banerjee, A. K., Das, S., Jena, A., Ravichandran, R., Sahi, U. P., Kumar, R., Kapoor, N., Kalia, V. K., Dwarakanath, B. S., and Jain, V. (1996) Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas. Int. J. Radiat. Oncol. Biol. Phys. 35, 103-111
-
(1996)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.35
, pp. 103-111
-
-
Mohanti, B.K.1
Rath, G.K.2
Anantha, N.3
Kannan, V.4
Das, B.S.5
Chandramouli, B.A.6
Banerjee, A.K.7
Das, S.8
Jena, A.9
Ravichandran, R.10
Sahi, U.P.11
Kumar, R.12
Kapoor, N.13
Kalia, V.K.14
Dwarakanath, B.S.15
Jain, V.16
-
23
-
-
23044507635
-
Optimizing cancer radiotherapy with 2-deoxy-D-glucose dose escalation studies in patients with glioblastoma multiforme
-
Singh, D., Banerji, A. K., Dwarakanath, B. S., Tripathi, R. P., Gupta, J. P., Mathew, T. L., Ravindranath, T., and Jain, V. (2005) Optimizing cancer radiotherapy with 2-deoxy-D-glucose dose escalation studies in patients with glioblastoma multiforme. Strahlenther Onkol. 181, 507-514
-
(2005)
Strahlenther Onkol
, vol.181
, pp. 507-514
-
-
Singh, D.1
Banerji, A.K.2
Dwarakanath, B.S.3
Tripathi, R.P.4
Gupta, J.P.5
Mathew, T.L.6
Ravindranath, T.7
Jain, V.8
-
24
-
-
84962732841
-
Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53-deficiency-driven castrationresistant prostate cancer
-
Wang, L., Wang, J., Xiong, H., Wu, F., Lan, T., Zhang, Y., Guo, X., Wang, H., Saleem, M., Jiang, C., Lu, J., and Deng, Y. (2016) Co-targeting hexokinase 2-mediated Warburg effect and ULK1-dependent autophagy suppresses tumor growth of PTEN- and TP53-deficiency-driven castrationresistant prostate cancer. EBioMedicine 7, 50-61
-
(2016)
EBioMedicine
, vol.7
, pp. 50-61
-
-
Wang, L.1
Wang, J.2
Xiong, H.3
Wu, F.4
Lan, T.5
Zhang, Y.6
Guo, X.7
Wang, H.8
Saleem, M.9
Jiang, C.10
Lu, J.11
Deng, Y.12
-
25
-
-
0036196425
-
Activation and caspase-mediated inhibition of PARP: A molecular switch between fibroblast necrosis and apoptosis in death receptor signaling
-
Los, M., Mozoluk, M., Ferrari, D., Stepczynska, A., Stroh, C., Renz, A., Herceg, Z., Wang, Z. Q., and Schulze-Osthoff, K. (2002) Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling. Mol. Biol. Cell 13, 978-988
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 978-988
-
-
Los, M.1
Mozoluk, M.2
Ferrari, D.3
Stepczynska, A.4
Stroh, C.5
Renz, A.6
Herceg, Z.7
Wang, Z.Q.8
Schulze-Osthoff, K.9
-
26
-
-
84930044531
-
Live to die another way: Modes of programmed cell death and the signals emanating from dying cells
-
Fuchs, Y., and Steller, H. (2015) Live to die another way: modes of programmed cell death and the signals emanating from dying cells. Nat. Rev. Mol. Cell Biol. 16, 329-344
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 329-344
-
-
Fuchs, Y.1
Steller, H.2
-
27
-
-
84958103915
-
Ferroptosis: Death by lipid peroxidation
-
Yang, W. S., and Stockwell, B. R. (2016) Ferroptosis: death by lipid peroxidation. Trends Cell Biol. 26, 165-176
-
(2016)
Trends Cell Biol.
, vol.26
, pp. 165-176
-
-
Yang, W.S.1
Stockwell, B.R.2
-
28
-
-
67650222474
-
In search of an autophagomometer
-
Rubinsztein, D. C., Cuervo, A. M., Ravikumar, B., Sarkar, S., Korolchuk, V., Kaushik, S., and Klionsky, D. J. (2009) In search of an "autophagomometer." Autophagy 5, 585-589
-
(2009)
Autophagy
, vol.5
, pp. 585-589
-
-
Rubinsztein, D.C.1
Cuervo, A.M.2
Ravikumar, B.3
Sarkar, S.4
Korolchuk, V.5
Kaushik, S.6
Klionsky, D.J.7
-
29
-
-
29944438881
-
Necrotic death as a cell fate
-
Zong, W. X., and Thompson, C. B. (2006) Necrotic death as a cell fate. Genes Dev. 20, 1-15
-
(2006)
Genes Dev.
, vol.20
, pp. 1-15
-
-
Zong, W.X.1
Thompson, C.B.2
-
30
-
-
34249868200
-
Vitamin E, antioxidant and nothing more
-
Traber, M. G., and Atkinson, J. (2007) Vitamin E, antioxidant and nothing more. Free Radic. Biol. Med. 43, 4-15
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 4-15
-
-
Traber, M.G.1
Atkinson, J.2
-
31
-
-
0013936320
-
Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria
-
Hackenbrock, C. R. (1966) Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria. J. Cell Biol. 30, 269-297
-
(1966)
J. Cell Biol.
, vol.30
, pp. 269-297
-
-
Hackenbrock, C.R.1
-
32
-
-
85024804258
-
Reversible and irreversible changes in the fine structure of nervous tissue during oxygen and glucose deprivation
-
Def Webster, H., and Ames, A. (1965) Reversible and irreversible changes in the fine structure of nervous tissue during oxygen and glucose deprivation. J. Cell Biol. 26, 885-909
-
(1965)
J. Cell Biol.
, vol.26
, pp. 885-909
-
-
Def Webster, H.1
Ames, A.2
-
33
-
-
79956014819
-
Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells
-
Yoon, Y. H., Cho, K. S., Hwang, J. J., Lee, S. J., Choi, J. A., and Koh, J. Y. (2010) Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells. Invest. Ophthalmol. Vis. Sci. 51, 6030- 6037
-
(2010)
Invest. Ophthalmol. Vis. Sci.
, vol.51
, pp. 6030-6037
-
-
Yoon, Y.H.1
Cho, K.S.2
Hwang, J.J.3
Lee, S.J.4
Choi, J.A.5
Koh, J.Y.6
-
34
-
-
84862189804
-
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration
-
Dehay, B., Ramirez, A., Martinez-Vicente, M., Perier, C., Canron, M. H., Doudnikoff, E., Vital, A., Vila, M., Klein, C., and Bezard, E. (2012) Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. Proc. Natl. Acad. Sci. U.S.A. 109, 9611-9616
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 9611-9616
-
-
Dehay, B.1
Ramirez, A.2
Martinez-Vicente, M.3
Perier, C.4
Canron, M.H.5
Doudnikoff, E.6
Vital, A.7
Vila, M.8
Klein, C.9
Bezard, E.10
-
35
-
-
84875615728
-
The dual PI3K/mTOR inhibitor NVP-BEZ235 and chloroquine synergize to trigger apoptosis via mitochondrial-lysosomal cross-talk
-
Seitz, C., Hugle, M., Cristofanon, S., Tchoghandjian, A., and Fulda, S. (2013) The dual PI3K/mTOR inhibitor NVP-BEZ235 and chloroquine synergize to trigger apoptosis via mitochondrial-lysosomal cross-talk. Int. J. Cancer 132, 2682-2693
-
(2013)
Int. J. Cancer
, vol.132
, pp. 2682-2693
-
-
Seitz, C.1
Hugle, M.2
Cristofanon, S.3
Tchoghandjian, A.4
Fulda, S.5
-
36
-
-
0038677510
-
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
-
Boya, P., Gonzalez-Polo, R. A., Poncet, D., Andreau, K., Vieira, H. L., Roumier, T., Perfettini, J. L., and Kroemer, G. (2003) Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 22, 3927-3936
-
(2003)
Oncogene
, vol.22
, pp. 3927-3936
-
-
Boya, P.1
Gonzalez-Polo, R.A.2
Poncet, D.3
Andreau, K.4
Vieira, H.L.5
Roumier, T.6
Perfettini, J.L.7
Kroemer, G.8
-
37
-
-
0038529617
-
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
-
Boya, P., Andreau, K., Poncet, D., Zamzami, N., Perfettini, J. L., Metivier, D., Ojcius, D. M., Jäättelä, M., and Kroemer, G. (2003) Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J. Exp. Med. 197, 1323-1334
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1323-1334
-
-
Boya, P.1
Andreau, K.2
Poncet, D.3
Zamzami, N.4
Perfettini, J.L.5
Metivier, D.6
Ojcius, D.M.7
Jäättelä, M.8
Kroemer, G.9
-
38
-
-
80053592700
-
Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic
-
Denamur, S., Tyteca, D., Marchand-Brynaert, J., Van Bambeke, F., Tulkens, P. M., Courtoy, P. J., and Mingeot-Leclercq, M. P. (2011) Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic. Free Radic. Biol. Med. 51, 1656-1665
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 1656-1665
-
-
Denamur, S.1
Tyteca, D.2
Marchand-Brynaert, J.3
Van Bambeke, F.4
Tulkens, P.M.5
Courtoy, P.J.6
Mingeot-Leclercq, M.P.7
-
39
-
-
0031760170
-
Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes
-
Mueller, W. M., Gregoire, F. M., Stanhope, K. L., Mobbs, C. V., Mizuno, T. M., Warden, C. H., Stern, J. S., and Havel, P. J. (1998) Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology 139, 551-558
-
(1998)
Endocrinology
, vol.139
, pp. 551-558
-
-
Mueller, W.M.1
Gregoire, F.M.2
Stanhope, K.L.3
Mobbs, C.V.4
Mizuno, T.M.5
Warden, C.H.6
Stern, J.S.7
Havel, P.J.8
-
40
-
-
0033617296
-
Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes
-
Malhotra, R., and Brosius, F. C., 3rd. (1999) Glucose uptake and glycolysis reduce hypoxia-induced apoptosis in cultured neonatal rat cardiac myocytes. J. Biol. Chem. 274, 12567-12575
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12567-12575
-
-
Malhotra, R.1
Brosius, C.F.2
-
41
-
-
84858782079
-
AMPK: A nutrient and energy sensor that maintains energy homeostasis
-
Hardie, D. G., Ross, F. A., and Hawley, S. A. (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13, 251-262
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
42
-
-
0037427440
-
Mitochondrial permeability transition: A common pathway to necrosis and apoptosis
-
Kim, J. S., He, L., and Lemasters, J. J. (2003) Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochem. Biophys. Res. Commun. 304, 463-470
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 463-470
-
-
Kim, J.S.1
He, L.2
Lemasters, J.J.3
-
43
-
-
47949125299
-
Apoptosis supercedes necrosis in mitochondrial DNA-depleted Jurkat cells by cleavage of receptorinteracting protein and inhibition of lysosomal cathepsin
-
Sato, T., Machida, T., Takahashi, S., Murase, K., Kawano, Y., Hayashi, T., Iyama, S., Takada, K., Kuribayashi, K., Sato, Y., Kobune, M., Takimoto, R., Matsunaga, T., Kato, J., and Niitsu, Y. (2008) Apoptosis supercedes necrosis in mitochondrial DNA-depleted Jurkat cells by cleavage of receptorinteracting protein and inhibition of lysosomal cathepsin. J. Immunol. 181, 197-207
-
(2008)
J. Immunol.
, vol.181
, pp. 197-207
-
-
Sato, T.1
Machida, T.2
Takahashi, S.3
Murase, K.4
Kawano, Y.5
Hayashi, T.6
Iyama, S.7
Takada, K.8
Kuribayashi, K.9
Sato, Y.10
Kobune, M.11
Takimoto, R.12
Matsunaga, T.13
Kato, J.14
Niitsu, Y.15
-
44
-
-
0037636369
-
Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis
-
Gottlieb, E., Armour, S. M., Harris, M. H., and Thompson, C. B. (2003) Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis. Cell Death Differ. 10, 709-717
-
(2003)
Cell Death Differ.
, vol.10
, pp. 709-717
-
-
Gottlieb, E.1
Armour, S.M.2
Harris, M.H.3
Thompson, C.B.4
-
45
-
-
79953662111
-
Mycobacterium tuberculosis induces an atypical cell death mode to escape from infected macrophages
-
Lee, J., Repasy, T., Papavinasasundaram, K., Sassetti, C., and Kornfeld, H. (2011) Mycobacterium tuberculosis induces an atypical cell death mode to escape from infected macrophages. PLoS ONE 6, e18367
-
(2011)
PLoS ONE
, vol.6
, pp. e18367
-
-
Lee, J.1
Repasy, T.2
Papavinasasundaram, K.3
Sassetti, C.4
Kornfeld, H.5
-
46
-
-
79951580969
-
Lysosomal membrane permeabilization causes oxidative stress and ferritin induction in macrophages
-
Ghosh, M., Carlsson, F., Laskar, A., Yuan, X. M., and Li, W. (2011) Lysosomal membrane permeabilization causes oxidative stress and ferritin induction in macrophages. FEBS Lett. 585, 623-629
-
(2011)
FEBS Lett.
, vol.585
, pp. 623-629
-
-
Ghosh, M.1
Carlsson, F.2
Laskar, A.3
Yuan, X.M.4
Li, W.5
-
47
-
-
79955629653
-
Mitochondrial consumption of cytosolic ATP: Not so fast
-
Chinopoulos, C. (2011) Mitochondrial consumption of cytosolic ATP: not so fast. FEBS Lett. 585, 1255-1259
-
(2011)
FEBS Lett.
, vol.585
, pp. 1255-1259
-
-
Chinopoulos, C.1
-
48
-
-
0035826677
-
Hypersensitization of tumor cells to glycolytic inhibitors
-
Liu, H., Hu, Y. P., Savaraj, N., Priebe, W., and Lampidis, T. J. (2001) Hypersensitization of tumor cells to glycolytic inhibitors. Biochemistry 40, 5542-5547
-
(2001)
Biochemistry
, vol.40
, pp. 5542-5547
-
-
Liu, H.1
Hu, Y.P.2
Savaraj, N.3
Priebe, W.4
Lampidis, T.J.5
-
49
-
-
33847045900
-
Mitochondrial oxidative stress: Implications for cell death
-
Orrenius, S., Gogvadze, V., and Zhivotovsky, B. (2007) Mitochondrial oxidative stress: implications for cell death. Annu. Rev. Pharmacol. Toxicol. 47, 143-183
-
(2007)
Annu. Rev. Pharmacol. Toxicol
, vol.47
, pp. 143-183
-
-
Orrenius, S.1
Gogvadze, V.2
Zhivotovsky, B.3
-
50
-
-
84892569830
-
An overview of autophagy: Morphology, mechanism, and regulation
-
Parzych, K. R., and Klionsky, D. J. (2014) An overview of autophagy: morphology, mechanism, and regulation. Antioxid. Redox Signal. 20, 460- 473
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 460-473
-
-
Parzych, K.R.1
Klionsky, D.J.2
-
51
-
-
84891346876
-
Autophagy and cell death
-
Yonekawa, T., and Thorburn, A. (2013) Autophagy and cell death. Essays Biochem. 55, 105-117
-
(2013)
Essays Biochem
, vol.55
, pp. 105-117
-
-
Yonekawa, T.1
Thorburn, A.2
-
52
-
-
79952319773
-
Mitochondria removal by autophagy
-
Wang, K., and Klionsky, D. J. (2011) Mitochondria removal by autophagy. Autophagy 7, 297-300
-
(2011)
Autophagy
, vol.7
, pp. 297-300
-
-
Wang, K.1
Klionsky, D.J.2
-
53
-
-
34249279169
-
GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation
-
Colell, A., Ricci, J. E., Tait, S., Milasta, S., Maurer, U., Bouchier-Hayes, L., Fitzgerald, P., Guio-Carrion, A., Waterhouse, N. J., Li, C. W., Mari, B., Barbry, P., Newmeyer, D. D., Beere, H. M., and Green, D. R. (2007) GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation. Cell 129, 983-997
-
(2007)
Cell
, vol.129
, pp. 983-997
-
-
Colell, A.1
Ricci, J.E.2
Tait, S.3
Milasta, S.4
Maurer, U.5
Bouchier-Hayes, L.6
Fitzgerald, P.7
Guio-Carrion, A.8
Waterhouse, N.J.9
Li, C.W.10
Mari, B.11
Barbry, P.12
Newmeyer, D.D.13
Beere, H.M.14
Green, D.R.15
-
54
-
-
77952909686
-
Resistance to caspase-independent cell death requires persistence of intact mitochondria
-
Tait, S. W., Parsons, M. J., Llambi, F., Bouchier-Hayes, L., Connell, S., Muñoz-Pinedo, C., and Green, D. R. (2010) Resistance to caspase-independent cell death requires persistence of intact mitochondria. Dev. Cell 18, 802-813
-
(2010)
Dev. Cell
, vol.18
, pp. 802-813
-
-
Tait, S.W.1
Parsons, M.J.2
Llambi, F.3
Bouchier-Hayes, L.4
Connell, S.5
Muñoz-Pinedo, C.6
Green, D.R.7
-
55
-
-
77955458963
-
The combination of metformin and 2-deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells
-
Ben Sahra, I., Tanti, J. F., and Bost, F. (2010) The combination of metformin and 2-deoxyglucose inhibits autophagy and induces AMPK-dependent apoptosis in prostate cancer cells. Autophagy 6, 670-671
-
(2010)
Autophagy
, vol.6
, pp. 670-671
-
-
Ben Sahra, I.1
Tanti, J.F.2
Bost, F.3
-
56
-
-
34248203863
-
Structure of Atg5. Atg16, a complex essential for autophagy
-
Matsushita, M., Suzuki, N. N., Obara, K., Fujioka, Y., Ohsumi, Y., and Inagaki, F. (2007) Structure of Atg5.Atg16, a complex essential for autophagy. J. Biol. Chem. 282, 6763- 6772
-
(2007)
J. Biol. Chem
, vol.282
, pp. 6763-6772
-
-
Matsushita, M.1
Suzuki, N.N.2
Obara, K.3
Fujioka, Y.4
Ohsumi, Y.5
Inagaki, F.6
-
57
-
-
21044455137
-
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
-
Komatsu, M., Waguri, S., Ueno, T., Iwata, J., Murata, S., Tanida, I., Ezaki, J., Mizushima, N., Ohsumi, Y., Uchiyama, Y., Kominami, E., Tanaka, K., and Chiba, T. (2005) Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J. Cell Biol. 169, 425-434
-
(2005)
J. Cell Biol.
, vol.169
, pp. 425-434
-
-
Komatsu, M.1
Waguri, S.2
Ueno, T.3
Iwata, J.4
Murata, S.5
Tanida, I.6
Ezaki, J.7
Mizushima, N.8
Ohsumi, Y.9
Uchiyama, Y.10
Kominami, E.11
Tanaka, K.12
Chiba, T.13
-
58
-
-
79954450327
-
2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion
-
Xi, H., Kurtoglu, M., Liu, H., Wangpaichitr, M., You, M., Liu, X., Savaraj, N., and Lampidis, T. J. (2011) 2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion. Cancer Chemother Pharmacol. 67, 899-910
-
(2011)
Cancer Chemother Pharmacol
, vol.67
, pp. 899-910
-
-
Xi, H.1
Kurtoglu, M.2
Liu, H.3
Wangpaichitr, M.4
You, M.5
Liu, X.6
Savaraj, N.7
Lampidis, T.J.8
-
59
-
-
56049108345
-
Therapeutic starvation and autophagy in prostate cancer: A new paradigm for targeting metabolism in cancer therapy
-
DiPaola, R. S., Dvorzhinski, D., Thalasila, A., Garikapaty, V., Doram, D., May, M., Bray, K., Mathew, R., Beaudoin, B., Karp, C., Stein, M., Foran, D. J., and White, E. (2008) Therapeutic starvation and autophagy in prostate cancer: a new paradigm for targeting metabolism in cancer therapy. Prostate 68, 1743-1752
-
(2008)
Prostate
, vol.68
, pp. 1743-1752
-
-
DiPaola, R.S.1
Dvorzhinski, D.2
Thalasila, A.3
Garikapaty, V.4
Doram, D.5
May, M.6
Bray, K.7
Mathew, R.8
Beaudoin, B.9
Karp, C.10
Stein, M.11
Foran, D.J.12
White, E.13
-
60
-
-
0023740948
-
Influence of 2-deoxy-D-glucose and arterial ischaemia on glucose oxidation and growth of liver cancer in the rat
-
Mack, P., Ahrén, B., Jeppsson, B., Kan, Z., and Bengmark, S. (1988) Influence of 2-deoxy-D-glucose and arterial ischaemia on glucose oxidation and growth of liver cancer in the rat. Eur. J. Cancer Clin. Oncol. 24, 1433-1437
-
(1988)
Eur. J. Cancer Clin. Oncol.
, vol.24
, pp. 1433-1437
-
-
Mack, P.1
Ahrén, B.2
Jeppsson, B.3
Kan, Z.4
Bengmark, S.5
-
61
-
-
82355169681
-
Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo
-
Sottnik, J. L., Lori, J. C., Rose, B. J., and Thamm, D. H. (2011) Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo. Clin. Exp. Metastasis 28, 865-875
-
(2011)
Clin. Exp. Metastasis
, vol.28
, pp. 865-875
-
-
Sottnik, J.L.1
Lori, J.C.2
Rose, B.J.3
Thamm, D.H.4
-
62
-
-
84885619223
-
Glycolysis inhibition sensitizes non-small cell lung cancer with T790M mutation to irreversible EGFR inhibitors via translational suppression of Mcl-1 by AMPK activation
-
Kim, S. M., Yun, M. R., Hong, Y. K., Solca, F., Kim, J. H., Kim, H. J., and Cho, B. C. (2013) Glycolysis inhibition sensitizes non-small cell lung cancer with T790M mutation to irreversible EGFR inhibitors via translational suppression of Mcl-1 by AMPK activation. Mol. Cancer Ther. 12, 2145-2156
-
(2013)
Mol. Cancer Ther.
, vol.12
, pp. 2145-2156
-
-
Kim, S.M.1
Yun, M.R.2
Hong, Y.K.3
Solca, F.4
Kim, J.H.5
Kim, H.J.6
Cho, B.C.7
-
63
-
-
68149169947
-
Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells
-
Fath, M. A., Diers, A. R., Aykin-Burns, N., Simons, A. L., Hua, L., and Spitz, D. R. (2009) Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells. Cancer Biol. Ther. 8, 1228-1236
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 1228-1236
-
-
Fath, M.A.1
Diers, A.R.2
Aykin-Burns, N.3
Simons, A.L.4
Hua, L.5
Spitz, D.R.6
-
64
-
-
56749161667
-
2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: A potential treatment for breast and prostate cancer
-
Tagg, S. L., Foster, P. A., Leese, M. P., Potter, B. V., Reed, M. J., Purohit, A., and Newman, S. P. (2008) 2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer. Br. J. Cancer 99, 1842-1848
-
(2008)
Br. J. Cancer
, vol.99
, pp. 1842-1848
-
-
Tagg, S.L.1
Foster, P.A.2
Leese, M.P.3
Potter, B.V.4
Reed, M.J.5
Purohit, A.6
Newman, S.P.7
-
65
-
-
35449002129
-
Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging. Int
-
Simons, A. L., Fath, M. A., Mattson, D. M., Smith, B. J., Walsh, S. A., Graham, M. M., Hichwa, R. D., Buatti, J. M., Dornfeld, K., and Spitz, D. R. (2007) Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging. Int. J. Radiat. Oncol. Biol. Phys. 69, 1222-1230
-
(2007)
J. Radiat. Oncol. Biol. Phys.
, vol.69
, pp. 1222-1230
-
-
Simons, A.L.1
Fath, M.A.2
Mattson, D.M.3
Smith, B.J.4
Walsh, S.A.5
Graham, M.M.6
Hichwa, R.D.7
Buatti, J.M.8
Dornfeld, K.9
Spitz, D.R.10
-
66
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. (1956) On the origin of cancer cells. Science 123, 309-314
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
67
-
-
33744828248
-
Glucose withdrawal induces oxidative stress followed by apoptosis in glioblastoma cells but not in normal human astrocytes
-
Jelluma, N., Yang, X., Stokoe, D., Evan, G. I., Dansen, T. B., and Haas-Kogan, D. A. (2006) Glucose withdrawal induces oxidative stress followed by apoptosis in glioblastoma cells but not in normal human astrocytes. Mol. Cancer Res. 4, 319-330
-
(2006)
Mol. Cancer Res.
, vol.4
, pp. 319-330
-
-
Jelluma, N.1
Yang, X.2
Stokoe, D.3
Evan, G.I.4
Dansen, T.B.5
Haas-Kogan, D.A.6
-
68
-
-
0345791482
-
Extracellular acidification alters lysosomal trafficking in human breast cancer cells
-
Glunde, K., Guggino, S. E., Solaiyappan, M., Pathak, A. P., Ichikawa, Y., and Bhujwalla, Z. M. (2003) Extracellular acidification alters lysosomal trafficking in human breast cancer cells. Neoplasia 5, 533-545
-
(2003)
Neoplasia
, vol.5
, pp. 533-545
-
-
Glunde, K.1
Guggino, S.E.2
Solaiyappan, M.3
Pathak, A.P.4
Ichikawa, Y.5
Bhujwalla, Z.M.6
-
69
-
-
0037223288
-
Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor α-induced cell death
-
Ono, K., Kim, S. O., and Han, J. (2003) Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor α-induced cell death. Mol. Cell Biol. 23, 665-676
-
(2003)
Mol. Cell Biol
, vol.23
, pp. 665-676
-
-
Ono, K.1
Kim, S.O.2
Han, J.3
-
70
-
-
37549070672
-
Cysteine cathepsin proteases as pharmacological targets in cancer
-
Palermo, C., and Joyce, J. A. (2008) Cysteine cathepsin proteases as pharmacological targets in cancer. Trends Pharmacol. Sci. 29, 22-28
-
(2008)
Trends Pharmacol. Sci
, vol.29
, pp. 22-28
-
-
Palermo, C.1
Joyce, J.A.2
-
71
-
-
0019313317
-
Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
-
McCarthy, K. D., and de Vellis, J. (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol. 85, 890-902
-
(1980)
J. Cell Biol.
, vol.85
, pp. 890-902
-
-
McCarthy, K.D.1
De Vellis, J.2
-
72
-
-
22244452610
-
Novel platinum(IV) complexes induce rapid tumor cell death in vitro
-
Kaludjerović, G. N., Miljković, D., Momcilović, M., Djinović, V. M., Mostarica Stojković;, M., Sabo, T. J., and Trajković;, V. (2005) Novel platinum(IV) complexes induce rapid tumor cell death in vitro. Int. J. Cancer 116, 479- 486
-
(2005)
Int. J. Cancer
, vol.116
, pp. 479-486
-
-
Kaludjerović, G.N.1
Miljković, D.2
Momcilović, M.3
Djinović, M.4
Mostarica Stojković, M.5
Sabo, T.J.6
Trajković, V.7
-
73
-
-
0017084256
-
Combination chemotherapy in vitro with adriamycin. Observations of additive, antagonistic, and synergistic effects when used in twodrug combinations on cultured human lymphoma cells
-
Drewinko, B., Loo, T. L., Brown, B., Gottlieb, J. A., and Freireich, E. J. (1976) Combination chemotherapy in vitro with adriamycin. Observations of additive, antagonistic, and synergistic effects when used in twodrug combinations on cultured human lymphoma cells. Cancer Biochem. Biophys. 1, 187-195
-
(1976)
Cancer Biochem. Biophys
, vol.1
, pp. 187-195
-
-
Drewinko, B.1
Loo, T.L.2
Brown, B.3
Gottlieb, J.A.4
Freireich, E.J.5
-
74
-
-
84942077592
-
Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine
-
Vucicevic, L., Misirkic-Marjanovic, M., Paunovic, V., Kravic-Stevovic, T., Martinovic, T., Ciric, D., Maric, N., Petricevic, S., Harhaji-Trajkovic, L., Bumbasirevic, V., and Trajkovic, V. (2014) Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine. Autophagy 10, 2362-2378
-
(2014)
Autophagy
, vol.10
, pp. 2362-2378
-
-
Vucicevic, L.1
Misirkic-Marjanovic, M.2
Paunovic, V.3
Kravic-Stevovic, T.4
Martinovic, T.5
Ciric, D.6
Maric, N.7
Petricevic, S.8
Harhaji-Trajkovic, L.9
Bumbasirevic, V.10
Trajkovic, V.11
-
75
-
-
0033045425
-
The efficiency of systematic sampling in stereology: Reconsidered
-
Gundersen, H. J., Jensen, E. B., Kiêu, K., and Nielsen, J. (1999) The efficiency of systematic sampling in stereology: reconsidered. J. Microsc. 193, 199-211
-
(1999)
J. Microsc.
, vol.193
, pp. 199-211
-
-
Gundersen, H.J.1
Jensen, E.B.2
Kiêu, K.3
Nielsen, J.4
-
76
-
-
0036145133
-
Recommendations for the health monitoring of rodent and rabbit colonies in breeding and experimental units
-
Nicklas, W., Baneux, P., Boot, R., Decelle, T., Deeny, A. A., Fumanelli, M., and Illgen-Wilcke, B. (2002) Recommendations for the health monitoring of rodent and rabbit colonies in breeding and experimental units. Lab. Anim. 36, 20-42
-
(2002)
Lab. Anim
, vol.36
, pp. 20-42
-
-
Nicklas, W.1
Baneux, P.2
Boot, R.3
Decelle, T.4
Deeny, A.A.5
Fumanelli, M.6
Illgen-Wilcke, B.7
-
77
-
-
77952812169
-
Guidelines for the welfare and use of animals in cancer research
-
Workman, P., Aboagye, E. O., Balkwill, F., Balmain, A., Bruder, G., Chaplin, D. J., Double, J. A., Everitt, J., Farningham, D. A., Glennie, M. J., Kelland, L. R., Robinson, V., Stratford, I. J., Tozer, G. M., Watson, S., Wedge, S. R., and Eccles, S. A. (2010) Guidelines for the Welfare and Use of Animals in Cancer Research. Br. J. Cancer 102, 1555-1577
-
(2010)
Br. J. Cancer
, vol.102
, pp. 1555-1577
-
-
Workman, P.1
Aboagye, E.O.2
Balkwill, F.3
Balmain, A.4
Bruder, G.5
Chaplin, D.J.6
Double, J.A.7
Everitt, J.8
Farningham, D.A.9
Glennie, M.J.10
Kelland, L.R.11
Robinson, V.12
Stratford, I.J.13
Tozer, G.M.14
Watson, S.15
Wedge, S.R.16
Eccles, S.A.17
|