Induction of lysosomal dilatation, arrested autophagy, and cell death by chloroquine in cultured ARPE-19 cells

Investigative Ophthalmology and Visual Science

Volumn 51, Issue 11, 2010, Pages 6030-6037

  Yoon, Young Hee ^a   Cho, Kyung Sook ^a   Hwang, Jung Jin ^a   Lee, Sook Jeong ^a   Choi, Jeong A ^a   Koh, Jae Young ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; BIOLOGICAL MARKER; CHLOROQUINE; LACTATE DEHYDROGENASE; LC3 PROTEIN; PROTEIN P62; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEATH; CELL VACUOLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOLYSIS; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; LYSOSOME; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; UBIQUITINATION;

ANTIMALARIALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CASPASE 3; CELL DEATH; CELLS, CULTURED; CHLOROQUINE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOBLOTTING; L-LACTATE DEHYDROGENASE; LYSOSOMES; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; REACTIVE OXYGEN SPECIES; RETINAL PIGMENT EPITHELIUM; RNA-BINDING PROTEINS; TRANSFECTION; VACUOLES;

EID: 79956014819     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-5278     Document Type: Article

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