Glycolysis inhibition by 2-deoxy-d-glucose reverts the metastatic phenotype in vitro and in vivo

Clinical and Experimental Metastasis

Volumn 28, Issue 8, 2011, Pages 865-875

  Sottnik, Joseph L ^a   Lori, Janet C ^a   Rose, Barbara J ^a   Thamm, Douglas H ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Invasion; Metabolism; Mouse; Oxidative phosphorylation

Indexed keywords

CATHEPSIN L; CYTOSKELETON PROTEIN; DEOXYGLUCOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; DOG; DOSE RESPONSE; FEMALE; GLYCOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; MOUSE; NONHUMAN; OSTEOSARCOMA; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PROTEIN EXPRESSION; TISSUE TYPES;

ANIMALS; ANTIMETABOLITES; BLOTTING, WESTERN; BONE NEOPLASMS; CATHEPSIN L; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; DEOXYGLUCOSE; DOGS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOLYSIS; HUMANS; MICE; MICE, INBRED C3H; OSTEOSARCOMA; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PHENOTYPE; SURVIVAL RATE; TUMOR CELLS, CULTURED;

EID: 82355169681     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-011-9417-5     Document Type: Article

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