DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks

Molecular Cell

Volumn 63, Issue 4, 2016, Pages 633-646

  van Overbeek, Megan ^a   Capurso, Daniel ^a   Carter, Matthew M ^a   Thompson, Matthew S ^a   Frias, Elizabeth ^b   Russ, Carsten ^b   Reece Hoyes, John S ^b   Nye, Christopher ^a   Gradia, Scott ^a   Vidal, Bastien ^a   Zheng, Jiashun ^a   Hoffman, Gregory R ^b   Fuller, Christopher K ^a   May, Andrew P ^a  

^a Caribou Biosciences Inc   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR ASSOCIATED PROTEIN 9; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; ENDONUCLEASE; GUIDE RNA;

ARTICLE; CELL LINE; CONTROLLED STUDY; DNA REPAIR; DNA SEQUENCE; HUMAN GENOME; INDEL MUTATION; PRIMARY CELL; CRISPR CAS SYSTEM; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; GENE EDITING; GENE EXPRESSION PROFILING; GENETIC TRANSFECTION; GENETICS; HCT 116 CELL LINE; HEK293 CELL LINE; HUMAN; K-562 CELL LINE; METABOLISM; PROCEDURES; RNA INTERFERENCE; TIME FACTOR;

BACTERIAL PROTEINS; CRISPR-CAS SYSTEMS; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; ENDONUCLEASES; GENE EDITING; GENE EXPRESSION PROFILING; HCT116 CELLS; HEK293 CELLS; HUMANS; K562 CELLS; RNA INTERFERENCE; RNA, GUIDE; TIME FACTORS; TRANSFECTION;

EID: 84992755580     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.06.037     Document Type: Article

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