-
1
-
-
0033600301
-
Molecular basis of the neurodegenerative disorders
-
[1] Martin, J.B., Molecular basis of the neurodegenerative disorders. N. Engl. J. Med. 340 (1999), 1970–1980.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1970-1980
-
-
Martin, J.B.1
-
2
-
-
3142514201
-
Protein aggregation and neurodegenerative disease
-
[2] Ross, C.A., Poirier, M.A., Protein aggregation and neurodegenerative disease. Nat. Med. 10:Suppl (2004), S10–S17.
-
(2004)
Nat. Med.
, vol.10
, pp. S10-S17
-
-
Ross, C.A.1
Poirier, M.A.2
-
3
-
-
0035827318
-
Protein misfolding and disease; protein refolding and therapy
-
[3] Soto, C., Protein misfolding and disease; protein refolding and therapy. FEBS Lett. 498 (2001), 204–207.
-
(2001)
FEBS Lett.
, vol.498
, pp. 204-207
-
-
Soto, C.1
-
4
-
-
0023583026
-
Prions and neurodegenerative diseases
-
[4] Prusiner, S.B., Prions and neurodegenerative diseases. N. Engl. J. Med. 317 (1987), 1571–1581.
-
(1987)
N. Engl. J. Med.
, vol.317
, pp. 1571-1581
-
-
Prusiner, S.B.1
-
5
-
-
0034916581
-
Prion diseases of humans and animals: their causes and molecular basis
-
[5] Collinge, J., Prion diseases of humans and animals: their causes and molecular basis. Annu. Rev. Neurosci. 24 (2001), 519–550.
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 519-550
-
-
Collinge, J.1
-
6
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
[6] Prusiner, S.B., Novel proteinaceous infectious particles cause scrapie. Science 216 (1982), 136–144.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
9
-
-
0030054010
-
Normal host prion protein necessary for scrapie-induced neurotoxicity
-
[9] Brandner, S., Isenmann, S., Raeber, A., Fischer, M., Sailer, A., Kobayashi, Y., Marino, S., Weissmann, C., Aguzzi, A., Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature 379 (1996), 339–343.
-
(1996)
Nature
, vol.379
, pp. 339-343
-
-
Brandner, S.1
Isenmann, S.2
Raeber, A.3
Fischer, M.4
Sailer, A.5
Kobayashi, Y.6
Marino, S.7
Weissmann, C.8
Aguzzi, A.9
-
10
-
-
0020490156
-
Identification of a protein that purifies with the scrapie prion
-
[10] Bolton, D.C., McKinley, M.P., Prusiner, S.B., Identification of a protein that purifies with the scrapie prion. Science 218 (1982), 1309–1311.
-
(1982)
Science
, vol.218
, pp. 1309-1311
-
-
Bolton, D.C.1
McKinley, M.P.2
Prusiner, S.B.3
-
11
-
-
0023663071
-
Scrapie prion protein contains a phosphatidylinositol glycolipid
-
[11] Stahl, N., Borchelt, D.R., Hsiao, K., Prusiner, S.B., Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell 51 (1987), 229–240.
-
(1987)
Cell
, vol.51
, pp. 229-240
-
-
Stahl, N.1
Borchelt, D.R.2
Hsiao, K.3
Prusiner, S.B.4
-
12
-
-
0011888936
-
Assignment of the human and mouse prion protein genes to homologous chromosomes
-
[12] Sparkes, R.S., Simon, M., Cohn, V.H., Fournier, R.E.K., Lem, J., Klisak, I., Heinzmann, C., Blatt, C., Lucero, M., Mohandas, T., Dearmond, S.J., Westaway, D., Prusiner, S.B., Weiner, L.P., Assignment of the human and mouse prion protein genes to homologous chromosomes. Proc. Natl. Acad. Sci. U. S. A. 83 (1986), 7358–7362.
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 7358-7362
-
-
Sparkes, R.S.1
Simon, M.2
Cohn, V.H.3
Fournier, R.E.K.4
Lem, J.5
Klisak, I.6
Heinzmann, C.7
Blatt, C.8
Lucero, M.9
Mohandas, T.10
Dearmond, S.J.11
Westaway, D.12
Prusiner, S.B.13
Weiner, L.P.14
-
13
-
-
0030790431
-
Prion protein NMR structure and species barrier for prion diseases
-
[13] Billeter, M., Riek, R., Wider, G., Hornemann, S., Glockshuber, R., Wuthrich, K., Prion protein NMR structure and species barrier for prion diseases. Proc. Natl. Acad. Sci. U. S. A. 94 (1997), 7281–7285.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 7281-7285
-
-
Billeter, M.1
Riek, R.2
Wider, G.3
Hornemann, S.4
Glockshuber, R.5
Wuthrich, K.6
-
14
-
-
0028962532
-
Prion protein gene variation among primates
-
[14] Schatzl, H.M., Da Costa, M., Taylor, L., Cohen, F.E., Prusiner, S.B., Prion protein gene variation among primates. J. Mol. Biol. 245 (1995), 362–374.
-
(1995)
J. Mol. Biol.
, vol.245
, pp. 362-374
-
-
Schatzl, H.M.1
Da Costa, M.2
Taylor, L.3
Cohen, F.E.4
Prusiner, S.B.5
-
15
-
-
0025910229
-
Molecular-biology of prion diseases
-
[15] Prusiner, S.B., Molecular-biology of prion diseases. Science 252 (1991), 1515–1522.
-
(1991)
Science
, vol.252
, pp. 1515-1522
-
-
Prusiner, S.B.1
-
16
-
-
0032488777
-
A transmembrane form of the prion protein in neurodegenerative disease
-
[16] Hegde, R.S., Mastrianni, J.A., Scott, M.R., DeFea, K.A., Tremblay, P., Torchia, M., DeArmond, S.J., Prusiner, S.B., Lingappa, V.R., A transmembrane form of the prion protein in neurodegenerative disease. Science 279 (1998), 827–834.
-
(1998)
Science
, vol.279
, pp. 827-834
-
-
Hegde, R.S.1
Mastrianni, J.A.2
Scott, M.R.3
DeFea, K.A.4
Tremblay, P.5
Torchia, M.6
DeArmond, S.J.7
Prusiner, S.B.8
Lingappa, V.R.9
-
17
-
-
0142184347
-
Endothelial cells express normal cellular prion protein
-
[17] Starke, R., Harrison, P., Gale, R., Mackie, I., Drummond, O., MacGregor, I., Machin, S., Endothelial cells express normal cellular prion protein. Br. J. Haematol. 123 (2003), 372–373.
-
(2003)
Br. J. Haematol.
, vol.123
, pp. 372-373
-
-
Starke, R.1
Harrison, P.2
Gale, R.3
Mackie, I.4
Drummond, O.5
MacGregor, I.6
Machin, S.7
-
18
-
-
0034665847
-
Signal transduction through prion protein
-
[18] Mouillet-Richard, S., Ermonval, M., Chebassier, C., Laplanche, J.L., Lehmann, S., Launay, J.M., Kellermann, O., Signal transduction through prion protein. Science 289 (2000), 1925–1928.
-
(2000)
Science
, vol.289
, pp. 1925-1928
-
-
Mouillet-Richard, S.1
Ermonval, M.2
Chebassier, C.3
Laplanche, J.L.4
Lehmann, S.5
Launay, J.M.6
Kellermann, O.7
-
19
-
-
0041302374
-
Cellular prion protein function in copper homeostasis and redox signalling at the synapse
-
[19] Vassallo, N., Herms, J., Cellular prion protein function in copper homeostasis and redox signalling at the synapse. J. Neurochem. 86 (2003), 538–544.
-
(2003)
J. Neurochem.
, vol.86
, pp. 538-544
-
-
Vassallo, N.1
Herms, J.2
-
20
-
-
61349201380
-
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
-
[20] Lauren, J., Gimbel, D.A., Nygaard, H.B., Gilbert, J.W., Strittmatter, S.M., Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature 457 (2009), 1128–1132.
-
(2009)
Nature
, vol.457
, pp. 1128-1132
-
-
Lauren, J.1
Gimbel, D.A.2
Nygaard, H.B.3
Gilbert, J.W.4
Strittmatter, S.M.5
-
21
-
-
0027332116
-
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins
-
[21] Pan, K.M., Baldwin, M., Nguyen, J., Gasset, M., Serban, A., Groth, D., Mehlhorn, I., Huang, Z., Fletterick, R.J., Cohen, F.E., et al. Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc. Natl. Acad. Sci. U. S. A. 90 (1993), 10962–10966.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 10962-10966
-
-
Pan, K.M.1
Baldwin, M.2
Nguyen, J.3
Gasset, M.4
Serban, A.5
Groth, D.6
Mehlhorn, I.7
Huang, Z.8
Fletterick, R.J.9
Cohen, F.E.10
-
22
-
-
0029937271
-
NMR structure of the mouse prion protein domain PrP(121–231)
-
[22] Riek, R., Hornemann, S., Wider, G., Billeter, M., Glockshuber, R., Wuthrich, K., NMR structure of the mouse prion protein domain PrP(121–231). Nature 382 (1996), 180–182.
-
(1996)
Nature
, vol.382
, pp. 180-182
-
-
Riek, R.1
Hornemann, S.2
Wider, G.3
Billeter, M.4
Glockshuber, R.5
Wuthrich, K.6
-
23
-
-
0028608963
-
Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein
-
[23] Hsiao, K.K., Groth, D., Scott, M., Yang, S.L., Serban, H., Rapp, D., Foster, D., Torchia, M., Dearmond, S.J., Prusiner, S.B., Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein. Proc. Natl. Acad. Sci. U. S. A. 91 (1994), 9126–9130.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 9126-9130
-
-
Hsiao, K.K.1
Groth, D.2
Scott, M.3
Yang, S.L.4
Serban, H.5
Rapp, D.6
Foster, D.7
Torchia, M.8
Dearmond, S.J.9
Prusiner, S.B.10
-
24
-
-
12644272790
-
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity
-
[24] Telling, G.C., Parchi, P., DeArmond, S.J., Cortelli, P., Montagna, P., Gabizon, R., Mastrianni, J., Lugaresi, E., Gambetti, P., Prusiner, S.B., Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science 274 (1996), 2079–2082.
-
(1996)
Science
, vol.274
, pp. 2079-2082
-
-
Telling, G.C.1
Parchi, P.2
DeArmond, S.J.3
Cortelli, P.4
Montagna, P.5
Gabizon, R.6
Mastrianni, J.7
Lugaresi, E.8
Gambetti, P.9
Prusiner, S.B.10
-
25
-
-
0028882424
-
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
-
[25] Telling, G.C., Scott, M., Mastrianni, J., Gabizon, R., Torchia, M., Cohen, F.E., DeArmond, S.J., Prusiner, S.B., Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein. Cell 83 (1995), 79–90.
-
(1995)
Cell
, vol.83
, pp. 79-90
-
-
Telling, G.C.1
Scott, M.2
Mastrianni, J.3
Gabizon, R.4
Torchia, M.5
Cohen, F.E.6
DeArmond, S.J.7
Prusiner, S.B.8
-
26
-
-
0014190760
-
Self-replication and scrapie
-
1043-&
-
[26] Griffith, J.S., Self-replication and scrapie. Nature, 215, 1967 1043-&.
-
(1967)
Nature
, vol.215
-
-
Griffith, J.S.1
-
27
-
-
0029052468
-
Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi(+)]
-
[27] Chernoff, Y.O., Lindquist, S.L., Ono, B., Ingevechtomov, S.G., Liebman, S.W., Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi(+)]. Science 268 (1995), 880–884.
-
(1995)
Science
, vol.268
, pp. 880-884
-
-
Chernoff, Y.O.1
Lindquist, S.L.2
Ono, B.3
Ingevechtomov, S.G.4
Liebman, S.W.5
-
28
-
-
0025720634
-
Novel properties and biology of scrapie prions
-
[28] Prusiner, S.B., Novel properties and biology of scrapie prions. Curr. Top. Microbiol. Immunol. 172 (1991), 233–257.
-
(1991)
Curr. Top. Microbiol. Immunol.
, vol.172
, pp. 233-257
-
-
Prusiner, S.B.1
-
29
-
-
0027195933
-
Seeding one-dimensional crystallization of amyloid - a pathogenic mechanism in Alzheimers-disease and scrapie
-
[29] Jarrett, J.T., Lansbury, P.T., Seeding one-dimensional crystallization of amyloid - a pathogenic mechanism in Alzheimers-disease and scrapie. Cell 73 (1993), 1055–1058.
-
(1993)
Cell
, vol.73
, pp. 1055-1058
-
-
Jarrett, J.T.1
Lansbury, P.T.2
-
30
-
-
0027270578
-
A kinetic model for amyloid formation in the prion diseases: importance of seeding
-
[30] Come, J.H., Fraser, P.E., Lansbury, P.T. Jr., A kinetic model for amyloid formation in the prion diseases: importance of seeding. Proc. Natl. Acad. Sci. U. S. A. 90 (1993), 5959–5963.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 5959-5963
-
-
Come, J.H.1
Fraser, P.E.2
Lansbury, P.T.3
-
31
-
-
0030155687
-
Prion replication and secondary nucleation
-
[31] Orgel, L.E., Prion replication and secondary nucleation. Chem. Biol. 3 (1996), 413–414.
-
(1996)
Chem. Biol.
, vol.3
, pp. 413-414
-
-
Orgel, L.E.1
-
32
-
-
0020804037
-
Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes
-
[32] Harding, C., Heuser, J., Stahl, P., Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes. J. Cell Biol. 97 (1983), 329–339.
-
(1983)
J. Cell Biol.
, vol.97
, pp. 329-339
-
-
Harding, C.1
Heuser, J.2
Stahl, P.3
-
33
-
-
79958048581
-
Body fluid derived exosomes as a novel template for clinical diagnostics
-
[33] Keller, S., Ridinger, J., Rupp, A.K., Janssen, J.W., Altevogt, P., Body fluid derived exosomes as a novel template for clinical diagnostics. J. Transl. Med., 9, 2011, 86.
-
(2011)
J. Transl. Med.
, vol.9
, pp. 86
-
-
Keller, S.1
Ridinger, J.2
Rupp, A.K.3
Janssen, J.W.4
Altevogt, P.5
-
34
-
-
43249109372
-
Isolation and characterization of exosomes from cell culture supernatants and biological fluids
-
Unit 3 22
-
[34] Thery, C., Amigorena, S., Raposo, G., Clayton, A., Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr. Protoc. Cell Biol., Chapter 3, 2006 Unit 3 22.
-
(2006)
Curr. Protoc. Cell Biol.
, vol.Chapter 3
-
-
Thery, C.1
Amigorena, S.2
Raposo, G.3
Clayton, A.4
-
35
-
-
0036676445
-
Exosomes: composition, biogenesis and function
-
[35] Thery, C., Zitvogel, L., Amigorena, S., Exosomes: composition, biogenesis and function. Nat. Rev. Immunol. 2 (2002), 569–579.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 569-579
-
-
Thery, C.1
Zitvogel, L.2
Amigorena, S.3
-
36
-
-
39749162770
-
The role of exosomes in the processing of proteins associated with neurodegenerative diseases
-
[36] Vella, L.J., Sharples, R.A., Nisbet, R.M., Cappai, R., Hill, A.F., The role of exosomes in the processing of proteins associated with neurodegenerative diseases. Eur. Biophys. J. 37 (2008), 323–332.
-
(2008)
Eur. Biophys. J.
, vol.37
, pp. 323-332
-
-
Vella, L.J.1
Sharples, R.A.2
Nisbet, R.M.3
Cappai, R.4
Hill, A.F.5
-
37
-
-
79953858598
-
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
-
[37] Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., Wood, M.J., Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat. Biotechnol. 29 (2011), 341–345.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 341-345
-
-
Alvarez-Erviti, L.1
Seow, Y.2
Yin, H.3
Betts, C.4
Lakhal, S.5
Wood, M.J.6
-
38
-
-
84875234646
-
Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders
-
[38] Schneider, A., Simons, M., Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders. Cell Tissue Res. 352 (2013), 33–47.
-
(2013)
Cell Tissue Res.
, vol.352
, pp. 33-47
-
-
Schneider, A.1
Simons, M.2
-
39
-
-
79955070767
-
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
-
[39] Mittelbrunn, M., Gutierrez-Vazquez, C., Villarroya-Beltri, C., Gonzalez, S., Sanchez-Cabo, F., Gonzalez, M.A., Bernad, A., Sanchez-Madrid, F., Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Nat. Commun., 2, 2011, 282.
-
(2011)
Nat. Commun.
, vol.2
, pp. 282
-
-
Mittelbrunn, M.1
Gutierrez-Vazquez, C.2
Villarroya-Beltri, C.3
Gonzalez, S.4
Sanchez-Cabo, F.5
Gonzalez, M.A.6
Bernad, A.7
Sanchez-Madrid, F.8
-
40
-
-
57049103401
-
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
-
1470–U1209
-
[40] Skog, J., Wurdinger, T., van Rijn, S., Meijer, D.H., Gainche, L., Sena-Esteves, M., Curry, W.T., Carter, B.S., Krichevsky, A.M., Breakefield, X.O., Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat. Cell Biol., 10, 2008 1470–U1209.
-
(2008)
Nat. Cell Biol.
, vol.10
-
-
Skog, J.1
Wurdinger, T.2
van Rijn, S.3
Meijer, D.H.4
Gainche, L.5
Sena-Esteves, M.6
Curry, W.T.7
Carter, B.S.8
Krichevsky, A.M.9
Breakefield, X.O.10
-
41
-
-
0030870321
-
Aggregation reroutes molecules from a recycling to a vesicle-mediated secretion pathway during reticulocyte maturation
-
[41] Vidal, M., Mangeat, P., Hoekstra, D., Aggregation reroutes molecules from a recycling to a vesicle-mediated secretion pathway during reticulocyte maturation. J. Cell Sci. 110:Pt 16 (1997), 1867–1877.
-
(1997)
J. Cell Sci.
, vol.110
, pp. 1867-1877
-
-
Vidal, M.1
Mangeat, P.2
Hoekstra, D.3
-
42
-
-
0023645106
-
Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)
-
[42] Johnstone, R.M., Adam, M., Hammond, J.R., Orr, L., Turbide, C., Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J. Biol. Chem. 262 (1987), 9412–9420.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 9412-9420
-
-
Johnstone, R.M.1
Adam, M.2
Hammond, J.R.3
Orr, L.4
Turbide, C.5
-
43
-
-
0029752791
-
Endocytosis and molecular sorting
-
[43] Mellman, I., Endocytosis and molecular sorting. Annu. Rev. Cell Dev. Biol. 12 (1996), 575–625.
-
(1996)
Annu. Rev. Cell Dev. Biol.
, vol.12
, pp. 575-625
-
-
Mellman, I.1
-
44
-
-
0025755923
-
Late endosomes derive from early endosomes by maturation
-
[44] Stoorvogel, W., Strous, G.J., Geuze, H.J., Oorschot, V., Schwartz, A.L., Late endosomes derive from early endosomes by maturation. Cell 65 (1991), 417–427.
-
(1991)
Cell
, vol.65
, pp. 417-427
-
-
Stoorvogel, W.1
Strous, G.J.2
Geuze, H.J.3
Oorschot, V.4
Schwartz, A.L.5
-
45
-
-
40049112564
-
Ceramide triggers budding of exosome vesicles into multivesicular endosomes
-
[45] Trajkovic, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brugger, B., Simons, M., Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science 319 (2008), 1244–1247.
-
(2008)
Science
, vol.319
, pp. 1244-1247
-
-
Trajkovic, K.1
Hsu, C.2
Chiantia, S.3
Rajendran, L.4
Wenzel, D.5
Wieland, F.6
Schwille, P.7
Brugger, B.8
Simons, M.9
-
46
-
-
0033767690
-
Exosome: from internal vesicle of the multivesicular body to intercellular signaling device
-
[46] Denzer, K., Kleijmeer, M.J., Heijnen, H.F., Stoorvogel, W., Geuze, H.J., Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. J. Cell Sci. 113:Pt 19 (2000), 3365–3374.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 3365-3374
-
-
Denzer, K.1
Kleijmeer, M.J.2
Heijnen, H.F.3
Stoorvogel, W.4
Geuze, H.J.5
-
47
-
-
67249110996
-
Multivesicular endosome biogenesis in the absence of ESCRTs
-
[47] Stuffers, S., Sem Wegner, C., Stenmark, H., Brech, A., Multivesicular endosome biogenesis in the absence of ESCRTs. Traffic 10 (2009), 925–937.
-
(2009)
Traffic
, vol.10
, pp. 925-937
-
-
Stuffers, S.1
Sem Wegner, C.2
Stenmark, H.3
Brech, A.4
-
48
-
-
0035958546
-
Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I
-
[48] Katzmann, D.J., Babst, M., Emr, S.D., Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106 (2001), 145–155.
-
(2001)
Cell
, vol.106
, pp. 145-155
-
-
Katzmann, D.J.1
Babst, M.2
Emr, S.D.3
-
49
-
-
84858230240
-
Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein
-
[49] Nabhan, J.F., Hu, R., Oh, R.S., Cohen, S.N., Lu, Q., Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 4146–4151.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 4146-4151
-
-
Nabhan, J.F.1
Hu, R.2
Oh, R.S.3
Cohen, S.N.4
Lu, Q.5
-
50
-
-
84863206297
-
Syndecan-syntenin-ALIX regulates the biogenesis of exosomes
-
[50] Baietti, M.F., Zhang, Z., Mortier, E., Melchior, A., Degeest, G., Geeraerts, A., Ivarsson, Y., Depoortere, F., Coomans, C., Vermeiren, E., Zimmermann, P., David, G., Syndecan-syntenin-ALIX regulates the biogenesis of exosomes. Nat. Cell Biol. 14 (2012), 677–685.
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 677-685
-
-
Baietti, M.F.1
Zhang, Z.2
Mortier, E.3
Melchior, A.4
Degeest, G.5
Geeraerts, A.6
Ivarsson, Y.7
Depoortere, F.8
Coomans, C.9
Vermeiren, E.10
Zimmermann, P.11
David, G.12
-
51
-
-
0032498539
-
Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent
-
[51] Mullock, B.M., Bright, N.A., Fearon, C.W., Gray, S.R., Luzio, J.P., Fusion of lysosomes with late endosomes produces a hybrid organelle of intermediate density and is NSF dependent. J. Cell Biol. 140 (1998), 591–601.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 591-601
-
-
Mullock, B.M.1
Bright, N.A.2
Fearon, C.W.3
Gray, S.R.4
Luzio, J.P.5
-
52
-
-
0029979181
-
Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes
-
[52] Futter, C.E., Pearse, A., Hewlett, L.J., Hopkins, C.R., Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes. J. Cell Biol. 132 (1996), 1011–1023.
-
(1996)
J. Cell Biol.
, vol.132
, pp. 1011-1023
-
-
Futter, C.E.1
Pearse, A.2
Hewlett, L.J.3
Hopkins, C.R.4
-
53
-
-
84903745685
-
The complex ultrastructure of the endolysosomal system
-
[53] Klumperman, J., Raposo, G., The complex ultrastructure of the endolysosomal system. Cold Spring Harb. Perspect. Biol., 6, 2014, a016857.
-
(2014)
Cold Spring Harb. Perspect. Biol.
, vol.6
, pp. a016857
-
-
Klumperman, J.1
Raposo, G.2
-
54
-
-
84904704297
-
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles
-
[54] Colombo, M., Raposo, G., Thery, C., Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu. Rev. Cell Dev. Biol. 30 (2014), 255–289.
-
(2014)
Annu. Rev. Cell Dev. Biol.
, vol.30
, pp. 255-289
-
-
Colombo, M.1
Raposo, G.2
Thery, C.3
-
55
-
-
0020956787
-
Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor
-
[55] Pan, B.T., Johnstone, R.M., Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor. Cell 33 (1983), 967–978.
-
(1983)
Cell
, vol.33
, pp. 967-978
-
-
Pan, B.T.1
Johnstone, R.M.2
-
56
-
-
0020511115
-
Transferrin recycling in reticulocytes: pH and iron are important determinants of ligand binding and processing
-
[56] Harding, C., Stahl, P., Transferrin recycling in reticulocytes: pH and iron are important determinants of ligand binding and processing. Biochem. Biophys. Res. Commun. 113 (1983), 650–658.
-
(1983)
Biochem. Biophys. Res. Commun.
, vol.113
, pp. 650-658
-
-
Harding, C.1
Stahl, P.2
-
57
-
-
0037006804
-
Transfer of scrapie prion infectivity by cell contact in culture
-
[57] Kanu, N., Imokawa, Y., Drechsel, D.N., Williamson, R.A., Birkett, C.R., Bostock, C.J., Brockes, J.P., Transfer of scrapie prion infectivity by cell contact in culture. Curr. Biol. CB 12 (2002), 523–530.
-
(2002)
Curr. Biol. CB
, vol.12
, pp. 523-530
-
-
Kanu, N.1
Imokawa, Y.2
Drechsel, D.N.3
Williamson, R.A.4
Birkett, C.R.5
Bostock, C.J.6
Brockes, J.P.7
-
58
-
-
61849178720
-
Prions hijack tunnelling nanotubes for intercellular spread
-
[58] Gousset, K., Schiff, E., Langevin, C., Marijanovic, Z., Caputo, A., Browman, D.T., Chenouard, N., de Chaumont, F., Martino, A., Enninga, J., Olivo-Marin, J.C., Mannel, D., Zurzolo, C., Prions hijack tunnelling nanotubes for intercellular spread. Nat. Cell Biol. 11 (2009), 328–336.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 328-336
-
-
Gousset, K.1
Schiff, E.2
Langevin, C.3
Marijanovic, Z.4
Caputo, A.5
Browman, D.T.6
Chenouard, N.7
de Chaumont, F.8
Martino, A.9
Enninga, J.10
Olivo-Marin, J.C.11
Mannel, D.12
Zurzolo, C.13
-
59
-
-
0029989258
-
B lymphocytes secrete antigen-presenting vesicles
-
[59] Raposo, G., Nijman, H.W., Stoorvogel, W., Liejendekker, R., Harding, C.V., Melief, C.J., Geuze, H.J., B lymphocytes secrete antigen-presenting vesicles. J. Exp. Med. 183 (1996), 1161–1172.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1161-1172
-
-
Raposo, G.1
Nijman, H.W.2
Stoorvogel, W.3
Liejendekker, R.4
Harding, C.V.5
Melief, C.J.6
Geuze, H.J.7
-
60
-
-
0031863853
-
Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes
-
[60] Zitvogel, L., Regnault, A., Lozier, A., Wolfers, J., Flament, C., Tenza, D., Ricciardi-Castagnoli, P., Raposo, G., Amigorena, S., Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nat. Med. 4 (1998), 594–600.
-
(1998)
Nat. Med.
, vol.4
, pp. 594-600
-
-
Zitvogel, L.1
Regnault, A.2
Lozier, A.3
Wolfers, J.4
Flament, C.5
Tenza, D.6
Ricciardi-Castagnoli, P.7
Raposo, G.8
Amigorena, S.9
-
61
-
-
20244373139
-
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming
-
[61] Wolfers, J., Lozier, A., Raposo, G., Regnault, A., Thery, C., Masurier, C., Flament, C., Pouzieux, S., Faure, F., Tursz, T., Angevin, E., Amigorena, S., Zitvogel, L., Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat. Med. 7 (2001), 297–303.
-
(2001)
Nat. Med.
, vol.7
, pp. 297-303
-
-
Wolfers, J.1
Lozier, A.2
Raposo, G.3
Regnault, A.4
Thery, C.5
Masurier, C.6
Flament, C.7
Pouzieux, S.8
Faure, F.9
Tursz, T.10
Angevin, E.11
Amigorena, S.12
Zitvogel, L.13
-
62
-
-
0036906477
-
Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes
-
[62] Thery, C., Duban, L., Segura, E., Veron, P., Lantz, O., Amigorena, S., Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes. Nat. Immunol. 3 (2002), 1156–1162.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1156-1162
-
-
Thery, C.1
Duban, L.2
Segura, E.3
Veron, P.4
Lantz, O.5
Amigorena, S.6
-
63
-
-
8544232810
-
TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway
-
[63] Amzallag, N., Passer, B.J., Allanic, D., Segura, E., Thery, C., Goud, B., Amson, R., Telerman, A., TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway. J. Biol. Chem. 279 (2004), 46104–46112.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 46104-46112
-
-
Amzallag, N.1
Passer, B.J.2
Allanic, D.3
Segura, E.4
Thery, C.5
Goud, B.6
Amson, R.7
Telerman, A.8
-
64
-
-
34347391544
-
A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner
-
[64] Chen, S.H., Wu, P.S., Chou, C.H., Yan, Y.T., Liu, H., Weng, S.Y., Yang-Yen, H.F., A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner. Mol. Biol. Cell 18 (2007), 2525–2532.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 2525-2532
-
-
Chen, S.H.1
Wu, P.S.2
Chou, C.H.3
Yan, Y.T.4
Liu, H.5
Weng, S.Y.6
Yang-Yen, H.F.7
-
65
-
-
7444246058
-
Translationally controlled tumor protein is a target of tumor reversion
-
[65] Tuynder, M., Fiucci, G., Prieur, S., Lespagnol, A., Geant, A., Beaucourt, S., Duflaut, D., Besse, S., Susini, L., Cavarelli, J., Moras, D., Amson, R., Telerman, A., Translationally controlled tumor protein is a target of tumor reversion. Proc. Natl. Acad. Sci. U. S. A. 101 (2004), 15364–15369.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 15364-15369
-
-
Tuynder, M.1
Fiucci, G.2
Prieur, S.3
Lespagnol, A.4
Geant, A.5
Beaucourt, S.6
Duflaut, D.7
Besse, S.8
Susini, L.9
Cavarelli, J.10
Moras, D.11
Amson, R.12
Telerman, A.13
-
66
-
-
84883301160
-
Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells
-
[66] Nanbo, A., Kawanishi, E., Yoshida, R., Yoshiyama, H., Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveola-dependent endocytosis and promote phenotypic modulation in target cells. J. Virol. 87 (2013), 10334–10347.
-
(2013)
J. Virol.
, vol.87
, pp. 10334-10347
-
-
Nanbo, A.1
Kawanishi, E.2
Yoshida, R.3
Yoshiyama, H.4
-
67
-
-
79251581240
-
Exosomes containing glycoprotein 350 released by EBV-transformed B cells selectively target B cells through CD21 and block EBV infection in vitro
-
[67] Vallhov, H., Gutzeit, C., Johansson, S.M., Nagy, N., Paul, M., Li, Q., Friend, S., George, T.C., Klein, E., Scheynius, A., Gabrielsson, S., Exosomes containing glycoprotein 350 released by EBV-transformed B cells selectively target B cells through CD21 and block EBV infection in vitro. J. Immunol. 186 (2011), 73–82.
-
(2011)
J. Immunol.
, vol.186
, pp. 73-82
-
-
Vallhov, H.1
Gutzeit, C.2
Johansson, S.M.3
Nagy, N.4
Paul, M.5
Li, Q.6
Friend, S.7
George, T.C.8
Klein, E.9
Scheynius, A.10
Gabrielsson, S.11
-
68
-
-
0141856621
-
The Trojan exosome hypothesis
-
[68] Gould, S.J., Booth, A.M., Hildreth, J.E., The Trojan exosome hypothesis. Proc. Natl. Acad. Sci. U. S. A. 100 (2003), 10592–10597.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 10592-10597
-
-
Gould, S.J.1
Booth, A.M.2
Hildreth, J.E.3
-
69
-
-
31444453892
-
Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection
-
[69] Wiley, R.D., Gummuluru, S., Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 738–743.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 738-743
-
-
Wiley, R.D.1
Gummuluru, S.2
-
70
-
-
0347993084
-
Evidence that HIV budding in primary macrophages occurs through the exosome release pathway
-
[70] Nguyen, D.G., Booth, A., Gould, S.J., Hildreth, J.E., Evidence that HIV budding in primary macrophages occurs through the exosome release pathway. J. Biol. Chem. 278 (2003), 52347–52354.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52347-52354
-
-
Nguyen, D.G.1
Booth, A.2
Gould, S.J.3
Hildreth, J.E.4
-
71
-
-
33644927263
-
Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane
-
[71] Booth, A.M., Fang, Y., Fallon, J.K., Yang, J.M., Hildreth, J.E., Gould, S.J., Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane. J. Cell Biol. 172 (2006), 923–935.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 923-935
-
-
Booth, A.M.1
Fang, Y.2
Fallon, J.K.3
Yang, J.M.4
Hildreth, J.E.5
Gould, S.J.6
-
72
-
-
0036788110
-
Human macrophages accumulate HIV-1 particles in MHC II compartments
-
[72] Raposo, G., Moore, M., Innes, D., Leijendekker, R., Leigh-Brown, A., Benaroch, P., Geuze, H., Human macrophages accumulate HIV-1 particles in MHC II compartments. Traffic 3 (2002), 718–729.
-
(2002)
Traffic
, vol.3
, pp. 718-729
-
-
Raposo, G.1
Moore, M.2
Innes, D.3
Leijendekker, R.4
Leigh-Brown, A.5
Benaroch, P.6
Geuze, H.7
-
73
-
-
77950430319
-
HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?
-
[73] Izquierdo-Useros, N., Naranjo-Gomez, M., Erkizia, I., Puertas, M.C., Borras, F.E., Blanco, J., Martinez-Picado, J., HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?. PLoS Pathog., 6, 2010, e1000740.
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1000740
-
-
Izquierdo-Useros, N.1
Naranjo-Gomez, M.2
Erkizia, I.3
Puertas, M.C.4
Borras, F.E.5
Blanco, J.6
Martinez-Picado, J.7
-
74
-
-
33646562516
-
Cellular prion protein is released on exosomes from activated platelets
-
[74] Robertson, C., Booth, S.A., Beniac, D.R., Coulthart, M.B., Booth, T.F., McNicol, A., Cellular prion protein is released on exosomes from activated platelets. Blood 107 (2006), 3907–3911.
-
(2006)
Blood
, vol.107
, pp. 3907-3911
-
-
Robertson, C.1
Booth, S.A.2
Beniac, D.R.3
Coulthart, M.B.4
Booth, T.F.5
McNicol, A.6
-
75
-
-
47049113636
-
Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid
-
[75] Vella, L.J., Greenwood, D.L., Cappai, R., Scheerlinck, J.P., Hill, A.F., Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid. Vet. Immunol. Immunopathol. 124 (2008), 385–393.
-
(2008)
Vet. Immunol. Immunopathol.
, vol.124
, pp. 385-393
-
-
Vella, L.J.1
Greenwood, D.L.2
Cappai, R.3
Scheerlinck, J.P.4
Hill, A.F.5
-
76
-
-
33645357271
-
Exosomes are released by cultured cortical neurones
-
[76] Faure, J., Lachenal, G., Court, M., Hirrlinger, J., Chatellard-Causse, C., Blot, B., Grange, J., Schoehn, G., Goldberg, Y., Boyer, V., Kirchhoff, F., Raposo, G., Garin, J., Sadoul, R., Exosomes are released by cultured cortical neurones. Mol. Cell. Neurosci. 31 (2006), 642–648.
-
(2006)
Mol. Cell. Neurosci.
, vol.31
, pp. 642-648
-
-
Faure, J.1
Lachenal, G.2
Court, M.3
Hirrlinger, J.4
Chatellard-Causse, C.5
Blot, B.6
Grange, J.7
Schoehn, G.8
Goldberg, Y.9
Boyer, V.10
Kirchhoff, F.11
Raposo, G.12
Garin, J.13
Sadoul, R.14
-
77
-
-
53349177064
-
Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles
-
[77] Alais, S., Simoes, S., Baas, D., Lehmann, S., Raposo, G., Darlix, J.L., Leblanc, P., Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles. Biol. Cell 100 (2008), 603–615.
-
(2008)
Biol. Cell
, vol.100
, pp. 603-615
-
-
Alais, S.1
Simoes, S.2
Baas, D.3
Lehmann, S.4
Raposo, G.5
Darlix, J.L.6
Leblanc, P.7
-
78
-
-
3042788972
-
Cells release prions in association with exosomes
-
[78] Fevrier, B., Vilette, D., Archer, F., Loew, D., Faigle, W., Vidal, M., Laude, H., Raposo, G., Cells release prions in association with exosomes. Proc. Natl. Acad. Sci. U. S. A. 101 (2004), 9683–9688.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 9683-9688
-
-
Fevrier, B.1
Vilette, D.2
Archer, F.3
Loew, D.4
Faigle, W.5
Vidal, M.6
Laude, H.7
Raposo, G.8
-
79
-
-
19444374721
-
Uptake and neuritic transport of scrapie prion protein coincident with infection of neuronal cells
-
[79] Magalhaes, A.C., Baron, G.S., Lee, K.S., Steele-Mortimer, O., Dorward, D., Prado, M.A., Caughey, B., Uptake and neuritic transport of scrapie prion protein coincident with infection of neuronal cells. J. Neurosci. Off. J. Soc. Neurosci. 25 (2005), 5207–5216.
-
(2005)
J. Neurosci. Off. J. Soc. Neurosci.
, vol.25
, pp. 5207-5216
-
-
Magalhaes, A.C.1
Baron, G.S.2
Lee, K.S.3
Steele-Mortimer, O.4
Dorward, D.5
Prado, M.A.6
Caughey, B.7
-
80
-
-
33947709328
-
Packaging of prions into exosomes is associated with a novel pathway of PrP processing
-
[80] Vella, L.J., Sharples, R.A., Lawson, V.A., Masters, C.L., Cappai, R., Hill, A.F., Packaging of prions into exosomes is associated with a novel pathway of PrP processing. J. Pathol. 211 (2007), 582–590.
-
(2007)
J. Pathol.
, vol.211
, pp. 582-590
-
-
Vella, L.J.1
Sharples, R.A.2
Lawson, V.A.3
Masters, C.L.4
Cappai, R.5
Hill, A.F.6
-
81
-
-
33645290776
-
The prion protein and lipid rafts
-
[81] Taylor, D.R., Hooper, N.M., The prion protein and lipid rafts. Mol. Membr. Biol. 23 (2006), 89–99.
-
(2006)
Mol. Membr. Biol.
, vol.23
, pp. 89-99
-
-
Taylor, D.R.1
Hooper, N.M.2
-
82
-
-
77957269172
-
Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy
-
[82] Tian, T., Wang, Y., Wang, H., Zhu, Z., Xiao, Z., Visualizing of the cellular uptake and intracellular trafficking of exosomes by live-cell microscopy. J. Cell. Biochem. 111 (2010), 488–496.
-
(2010)
J. Cell. Biochem.
, vol.111
, pp. 488-496
-
-
Tian, T.1
Wang, Y.2
Wang, H.3
Zhu, Z.4
Xiao, Z.5
-
83
-
-
0036500554
-
Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes
-
[83] Baron, G.S., Wehrly, K., Dorward, D.W., Chesebro, B., Caughey, B., Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes. EMBO J. 21 (2002), 1031–1040.
-
(2002)
EMBO J.
, vol.21
, pp. 1031-1040
-
-
Baron, G.S.1
Wehrly, K.2
Dorward, D.W.3
Chesebro, B.4
Caughey, B.5
-
84
-
-
24644486400
-
Prions and exosomes: from PrPc trafficking to PrPsc propagation
-
[84] Porto-Carreiro, I., Fevrier, B., Paquet, S., Vilette, D., Raposo, G., Prions and exosomes: from PrPc trafficking to PrPsc propagation. Blood Cells Mol. Dis. 35 (2005), 143–148.
-
(2005)
Blood Cells Mol. Dis.
, vol.35
, pp. 143-148
-
-
Porto-Carreiro, I.1
Fevrier, B.2
Paquet, S.3
Vilette, D.4
Raposo, G.5
-
85
-
-
27644524811
-
Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells
-
[85] Safaei, R., Larson, B.J., Cheng, T.C., Gibson, M.A., Otani, S., Naerdemann, W., Howell, S.B., Abnormal lysosomal trafficking and enhanced exosomal export of cisplatin in drug-resistant human ovarian carcinoma cells. Mol. Cancer Ther. 4 (2005), 1595–1604.
-
(2005)
Mol. Cancer Ther.
, vol.4
, pp. 1595-1604
-
-
Safaei, R.1
Larson, B.J.2
Cheng, T.C.3
Gibson, M.A.4
Otani, S.5
Naerdemann, W.6
Howell, S.B.7
-
86
-
-
33746593662
-
Alzheimer's disease beta-amyloid peptides are released in association with exosomes
-
[86] Rajendran, L., Honsho, M., Zahn, T.R., Keller, P., Geiger, K.D., Verkade, P., Simons, K., Alzheimer's disease beta-amyloid peptides are released in association with exosomes. Proc. Natl. Acad. Sci. U. S. A. 103 (2006), 11172–11177.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 11172-11177
-
-
Rajendran, L.1
Honsho, M.2
Zahn, T.R.3
Keller, P.4
Geiger, K.D.5
Verkade, P.6
Simons, K.7
-
87
-
-
43249087541
-
Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes
-
[87] Sharples, R.A., Vella, L.J., Nisbet, R.M., Naylor, R., Perez, K., Barnham, K.J., Masters, C.L., Hill, A.F., Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes. FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol. 22 (2008), 1469–1478.
-
(2008)
FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol.
, vol.22
, pp. 1469-1478
-
-
Sharples, R.A.1
Vella, L.J.2
Nisbet, R.M.3
Naylor, R.4
Perez, K.5
Barnham, K.J.6
Masters, C.L.7
Hill, A.F.8
-
88
-
-
34547093203
-
Alkalizing drugs induce accumulation of amyloid precursor protein byproducts in lumenal vesicles of multivesicular bodies
-
[88] Vingtdeux, V., Hamdane, M., Loyens, A., Gele, P., Drobeck, H., Begard, S., Galas, M.C., Delacourte, A., Beauvillain, J.C., Buee, L., Sergeant, N., Alkalizing drugs induce accumulation of amyloid precursor protein byproducts in lumenal vesicles of multivesicular bodies. J. Biol. Chem. 282 (2007), 18197–18205.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 18197-18205
-
-
Vingtdeux, V.1
Hamdane, M.2
Loyens, A.3
Gele, P.4
Drobeck, H.5
Begard, S.6
Galas, M.C.7
Delacourte, A.8
Beauvillain, J.C.9
Buee, L.10
Sergeant, N.11
-
89
-
-
0031891929
-
Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity
-
[89] Hock, C., Golombowski, S., Muller-Spahn, F., Naser, W., Beyreuther, K., Monning, U., Schenk, D., Vigo-Pelfrey, C., Bush, A.M., Moir, R., Tanzi, R.E., Growdon, J.H., Nitsch, R.M., Cerebrospinal fluid levels of amyloid precursor protein and amyloid beta-peptide in Alzheimer's disease and major depression - inverse correlation with dementia severity. Eur. Neurol. 39 (1998), 111–118.
-
(1998)
Eur. Neurol.
, vol.39
, pp. 111-118
-
-
Hock, C.1
Golombowski, S.2
Muller-Spahn, F.3
Naser, W.4
Beyreuther, K.5
Monning, U.6
Schenk, D.7
Vigo-Pelfrey, C.8
Bush, A.M.9
Moir, R.10
Tanzi, R.E.11
Growdon, J.H.12
Nitsch, R.M.13
-
90
-
-
0026572465
-
Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients
-
[90] Van Nostrand, W.E., Wagner, S.L., Shankle, W.R., Farrow, J.S., Dick, M., Rozemuller, J.M., Kuiper, M.A., Wolters, E.C., Zimmerman, J., Cotman, C.W., et al. Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients. Proc. Natl. Acad. Sci. U. S. A. 89 (1992), 2551–2555.
-
(1992)
Proc. Natl. Acad. Sci. U. S. A.
, vol.89
, pp. 2551-2555
-
-
Van Nostrand, W.E.1
Wagner, S.L.2
Shankle, W.R.3
Farrow, J.S.4
Dick, M.5
Rozemuller, J.M.6
Kuiper, M.A.7
Wolters, E.C.8
Zimmerman, J.9
Cotman, C.W.10
-
91
-
-
0037454478
-
Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice
-
[91] Liu, L., Tapiola, T., Herukka, S.K., Heikkila, M., Tanila, H., Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice. Neuroreport 14 (2003), 163–166.
-
(2003)
Neuroreport
, vol.14
, pp. 163-166
-
-
Liu, L.1
Tapiola, T.2
Herukka, S.K.3
Heikkila, M.4
Tanila, H.5
-
92
-
-
0025326190
-
Detection of soluble forms of the beta-amyloid precursor protein in human plasma
-
[92] Podlisny, M.B., Mammen, A.L., Schlossmacher, M.G., Palmert, M.R., Younkin, S.G., Selkoe, D.J., Detection of soluble forms of the beta-amyloid precursor protein in human plasma. Biochem. Biophys. Res. Commun. 167 (1990), 1094–1101.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.167
, pp. 1094-1101
-
-
Podlisny, M.B.1
Mammen, A.L.2
Schlossmacher, M.G.3
Palmert, M.R.4
Younkin, S.G.5
Selkoe, D.J.6
-
93
-
-
0033975837
-
Plasma and cerebrospinal fluid levels of amyloid beta proteins 1–40 and 1–42 in Alzheimer disease
-
[93] Mehta, P.D., Pirttila, T., Mehta, S.P., Sersen, E.A., Aisen, P.S., Wisniewski, H.M., Plasma and cerebrospinal fluid levels of amyloid beta proteins 1–40 and 1–42 in Alzheimer disease. Arch. Neurol. 57 (2000), 100–105.
-
(2000)
Arch. Neurol.
, vol.57
, pp. 100-105
-
-
Mehta, P.D.1
Pirttila, T.2
Mehta, S.P.3
Sersen, E.A.4
Aisen, P.S.5
Wisniewski, H.M.6
-
94
-
-
11844250511
-
Part of membrane-bound Abeta exists in rafts within senile plaques in Tg2576 mouse brain
-
[94] Kokubo, H., Saido, T.C., Iwata, N., Helms, J.B., Shinohara, R., Yamaguchi, H., Part of membrane-bound Abeta exists in rafts within senile plaques in Tg2576 mouse brain. Neurobiol. Aging 26 (2005), 409–418.
-
(2005)
Neurobiol. Aging
, vol.26
, pp. 409-418
-
-
Kokubo, H.1
Saido, T.C.2
Iwata, N.3
Helms, J.B.4
Shinohara, R.5
Yamaguchi, H.6
-
95
-
-
84959300206
-
Exosomal PrP drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity
-
[95] Falker, C., Hartmann, A., Guett, I., Dohler, F., Altmeppen, H., Betzel, C., Schubert, R., Thurm, D., Wegwitz, F., Joshi, P., Verderio, C., Krasemann, S., Glatzel, M., Exosomal PrP drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity. J. Neurochem. 137 (2015), 88–100.
-
(2015)
J. Neurochem.
, vol.137
, pp. 88-100
-
-
Falker, C.1
Hartmann, A.2
Guett, I.3
Dohler, F.4
Altmeppen, H.5
Betzel, C.6
Schubert, R.7
Thurm, D.8
Wegwitz, F.9
Joshi, P.10
Verderio, C.11
Krasemann, S.12
Glatzel, M.13
-
96
-
-
84859499570
-
Sphingolipid-modulated exosome secretion promotes clearance of amyloid-beta by microglia
-
[96] Yuyama, K., Sun, H., Mitsutake, S., Igarashi, Y., Sphingolipid-modulated exosome secretion promotes clearance of amyloid-beta by microglia. J. Biol. Chem. 287 (2012), 10977–10989.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 10977-10989
-
-
Yuyama, K.1
Sun, H.2
Mitsutake, S.3
Igarashi, Y.4
-
97
-
-
84906871864
-
Decreased Amyloid-beta pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice
-
[97] Yuyama, K., Sun, H., Sakai, S., Mitsutake, S., Okada, M., Tahara, H., Furukawa, J., Fujitani, N., Shinohara, Y., Igarashi, Y., Decreased Amyloid-beta pathologies by intracerebral loading of glycosphingolipid-enriched exosomes in Alzheimer model mice. J. Biol. Chem. 289 (2014), 24488–24498.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 24488-24498
-
-
Yuyama, K.1
Sun, H.2
Sakai, S.3
Mitsutake, S.4
Okada, M.5
Tahara, H.6
Furukawa, J.7
Fujitani, N.8
Shinohara, Y.9
Igarashi, Y.10
-
98
-
-
84856707794
-
Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease
-
[98] Saman, S., Kim, W., Raya, M., Visnick, Y., Miro, S., Jackson, B., McKee, A.C., Alvarez, V.E., Lee, N.C., Hall, G.F., Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J. Biol. Chem. 287 (2012), 3842–3849.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 3842-3849
-
-
Saman, S.1
Kim, W.2
Raya, M.3
Visnick, Y.4
Miro, S.5
Jackson, B.6
McKee, A.C.7
Alvarez, V.E.8
Lee, N.C.9
Hall, G.F.10
-
99
-
-
35448956015
-
Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis
-
[99] Gomes, C., Keller, S., Altevogt, P., Costa, J., Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis. Neurosci. Lett. 428 (2007), 43–46.
-
(2007)
Neurosci. Lett.
, vol.428
, pp. 43-46
-
-
Gomes, C.1
Keller, S.2
Altevogt, P.3
Costa, J.4
-
100
-
-
79952743365
-
Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells
-
[100] Munch, C., O'Brien, J., Bertolotti, A., Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 3548–3553.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 3548-3553
-
-
Munch, C.1
O'Brien, J.2
Bertolotti, A.3
-
101
-
-
84895796816
-
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms
-
[101] Grad, L.I., Yerbury, J.J., Turner, B.J., Guest, W.C., Pokrishevsky, E., O'Neill, M.A., Yanai, A., Silverman, J.M., Zeineddine, R., Corcoran, L., Kumita, J.R., Luheshi, L.M., Yousefi, M., Coleman, B.M., Hill, A.F., Plotkin, S.S., Mackenzie, I.R., Cashman, N.R., Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), 3620–3625.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 3620-3625
-
-
Grad, L.I.1
Yerbury, J.J.2
Turner, B.J.3
Guest, W.C.4
Pokrishevsky, E.5
O'Neill, M.A.6
Yanai, A.7
Silverman, J.M.8
Zeineddine, R.9
Corcoran, L.10
Kumita, J.R.11
Luheshi, L.M.12
Yousefi, M.13
Coleman, B.M.14
Hill, A.F.15
Plotkin, S.S.16
Mackenzie, I.R.17
Cashman, N.R.18
-
102
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
[102] Neumann, M., Sampathu, D.M., Kwong, L.K., Truax, A.C., Micsenyi, M.C., Chou, T.T., Bruce, J., Schuck, T., Grossman, M., Clark, C.M., McCluskey, L.F., Miller, B.L., Masliah, E., Mackenzie, I.R., Feldman, H., Feiden, W., Kretzschmar, H.A., Trojanowski, J.Q., Lee, V.M., Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314 (2006), 130–133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.19
-
103
-
-
84885484356
-
Prion-like properties of pathological TDP-43 aggregates from diseased brains
-
[103] Nonaka, T., Masuda-Suzukake, M., Arai, T., Hasegawa, Y., Akatsu, H., Obi, T., Yoshida, M., Murayama, S., Mann, D.M., Akiyama, H., Hasegawa, M., Prion-like properties of pathological TDP-43 aggregates from diseased brains. Cell Rep. 4 (2013), 124–134.
-
(2013)
Cell Rep.
, vol.4
, pp. 124-134
-
-
Nonaka, T.1
Masuda-Suzukake, M.2
Arai, T.3
Hasegawa, Y.4
Akatsu, H.5
Obi, T.6
Yoshida, M.7
Murayama, S.8
Mann, D.M.9
Akiyama, H.10
Hasegawa, M.11
-
104
-
-
84906330760
-
Limited role of free TDP-43 as a diagnostic tool in neurodegenerative diseases
-
[104] Feneberg, E., Steinacker, P., Lehnert, S., Schneider, A., Walther, P., Thal, D.R., Linsenmeier, M., Ludolph, A.C., Otto, M., Limited role of free TDP-43 as a diagnostic tool in neurodegenerative diseases. Amyotroph. Lateral Scler. Front. Degener. 15 (2014), 351–356.
-
(2014)
Amyotroph. Lateral Scler. Front. Degener.
, vol.15
, pp. 351-356
-
-
Feneberg, E.1
Steinacker, P.2
Lehnert, S.3
Schneider, A.4
Walther, P.5
Thal, D.R.6
Linsenmeier, M.7
Ludolph, A.C.8
Otto, M.9
-
105
-
-
0028376473
-
Induction of beta (A4)-amyloid in primates by injection of Alzheimer's disease brain homogenate. Comparison with transmission of spongiform encephalopathy
-
[105] Baker, H.F., Ridley, R.M., Duchen, L.W., Crow, T.J., Bruton, C.J., Induction of beta (A4)-amyloid in primates by injection of Alzheimer's disease brain homogenate. Comparison with transmission of spongiform encephalopathy. Mol. Neurobiol. 8 (1994), 25–39.
-
(1994)
Mol. Neurobiol.
, vol.8
, pp. 25-39
-
-
Baker, H.F.1
Ridley, R.M.2
Duchen, L.W.3
Crow, T.J.4
Bruton, C.J.5
-
106
-
-
67650077008
-
Transmission and spreading of tauopathy in transgenic mouse brain
-
[106] Clavaguera, F., Bolmont, T., Crowther, R.A., Abramowski, D., Frank, S., Probst, A., Fraser, G., Stalder, A.K., Beibel, M., Staufenbiel, M., Jucker, M., Goedert, M., Tolnay, M., Transmission and spreading of tauopathy in transgenic mouse brain. Nat. Cell Biol. 11 (2009), 909–913.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 909-913
-
-
Clavaguera, F.1
Bolmont, T.2
Crowther, R.A.3
Abramowski, D.4
Frank, S.5
Probst, A.6
Fraser, G.7
Stalder, A.K.8
Beibel, M.9
Staufenbiel, M.10
Jucker, M.11
Goedert, M.12
Tolnay, M.13
-
107
-
-
43249114934
-
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
-
[107] Kordower, J.H., Chu, Y., Hauser, R.A., Freeman, T.B., Olanow, C.W., Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat. Med. 14 (2008), 504–506.
-
(2008)
Nat. Med.
, vol.14
, pp. 504-506
-
-
Kordower, J.H.1
Chu, Y.2
Hauser, R.A.3
Freeman, T.B.4
Olanow, C.W.5
-
108
-
-
43249110200
-
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
-
[108] Li, J.Y., Englund, E., Holton, J.L., Soulet, D., Hagell, P., Lees, A.J., Lashley, T., Quinn, N.P., Rehncrona, S., Bjorklund, A., Widner, H., Revesz, T., Lindvall, O., Brundin, P., Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation. Nat. Med. 14 (2008), 501–503.
-
(2008)
Nat. Med.
, vol.14
, pp. 501-503
-
-
Li, J.Y.1
Englund, E.2
Holton, J.L.3
Soulet, D.4
Hagell, P.5
Lees, A.J.6
Lashley, T.7
Quinn, N.P.8
Rehncrona, S.9
Bjorklund, A.10
Widner, H.11
Revesz, T.12
Lindvall, O.13
Brundin, P.14
-
109
-
-
79551519276
-
alpha-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
-
[109] Hansen, C., Angot, E., Bergstrom, A.L., Steiner, J.A., Pieri, L., Paul, G., Outeiro, T.F., Melki, R., Kallunki, P., Fog, K., Li, J.Y., Brundin, P., alpha-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J. Clin. Investig. 121 (2011), 715–725.
-
(2011)
J. Clin. Investig.
, vol.121
, pp. 715-725
-
-
Hansen, C.1
Angot, E.2
Bergstrom, A.L.3
Steiner, J.A.4
Pieri, L.5
Paul, G.6
Outeiro, T.F.7
Melki, R.8
Kallunki, P.9
Fog, K.10
Li, J.Y.11
Brundin, P.12
-
110
-
-
0030687649
-
Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulation
-
[110] Raposo, G., Tenza, D., Mecheri, S., Peronet, R., Bonnerot, C., Desaymard, C., Accumulation of major histocompatibility complex class II molecules in mast cell secretory granules and their release upon degranulation. Mol. Biol. Cell 8 (1997), 2631–2645.
-
(1997)
Mol. Biol. Cell
, vol.8
, pp. 2631-2645
-
-
Raposo, G.1
Tenza, D.2
Mecheri, S.3
Peronet, R.4
Bonnerot, C.5
Desaymard, C.6
-
111
-
-
0034909926
-
Intestinal epithelial cells secrete exosome-like vesicles
-
[111] van Niel, G., Raposo, G., Candalh, C., Boussac, M., Hershberg, R., Cerf-Bensussan, N., Heyman, M., Intestinal epithelial cells secrete exosome-like vesicles. Gastroenterology 121 (2001), 337–349.
-
(2001)
Gastroenterology
, vol.121
, pp. 337-349
-
-
van Niel, G.1
Raposo, G.2
Candalh, C.3
Boussac, M.4
Hershberg, R.5
Cerf-Bensussan, N.6
Heyman, M.7
-
112
-
-
0035877018
-
Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles
-
[112] Thery, C., Boussac, M., Veron, P., Ricciardi-Castagnoli, P., Raposo, G., Garin, J., Amigorena, S., Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. J. Immunol. 166 (2001), 7309–7318.
-
(2001)
J. Immunol.
, vol.166
, pp. 7309-7318
-
-
Thery, C.1
Boussac, M.2
Veron, P.3
Ricciardi-Castagnoli, P.4
Raposo, G.5
Garin, J.6
Amigorena, S.7
-
113
-
-
84858444838
-
ExoCarta 2012: database of exosomal proteins, RNA and lipids
-
[113] Mathivanan, S., Fahner, C.J., Reid, G.E., Simpson, R.J., ExoCarta 2012: database of exosomal proteins, RNA and lipids. Nucleic Acids Res. 40 (2012), D1241–D1244.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. D1241-D1244
-
-
Mathivanan, S.1
Fahner, C.J.2
Reid, G.E.3
Simpson, R.J.4
-
114
-
-
79960096964
-
Exosomes: secreted vesicles and intercellular communications
-
[114] Thery, C., Exosomes: secreted vesicles and intercellular communications. F1000 Biol. Rep., 3, 2011, 15.
-
(2011)
F1000 Biol. Rep.
, vol.3
, pp. 15
-
-
Thery, C.1
-
115
-
-
61349173156
-
Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes
-
[115] Conde-Vancells, J., Rodriguez-Suarez, E., Embade, N., Gil, D., Matthiesen, R., Valle, M., Elortza, F., Lu, S.C., Mato, J.M., Falcon-Perez, J.M., Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes. J. Proteome Res. 7 (2008), 5157–5166.
-
(2008)
J. Proteome Res.
, vol.7
, pp. 5157-5166
-
-
Conde-Vancells, J.1
Rodriguez-Suarez, E.2
Embade, N.3
Gil, D.4
Matthiesen, R.5
Valle, M.6
Elortza, F.7
Lu, S.C.8
Mato, J.M.9
Falcon-Perez, J.M.10
-
116
-
-
77956867597
-
Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins
-
[116] Subra, C., Grand, D., Laulagnier, K., Stella, A., Lambeau, G., Paillasse, M., De Medina, P., Monsarrat, B., Perret, B., Silvente-Poirot, S., Poirot, M., Record, M., Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins. J. Lipid Res. 51 (2010), 2105–2120.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 2105-2120
-
-
Subra, C.1
Grand, D.2
Laulagnier, K.3
Stella, A.4
Lambeau, G.5
Paillasse, M.6
De Medina, P.7
Monsarrat, B.8
Perret, B.9
Silvente-Poirot, S.10
Poirot, M.11
Record, M.12
-
117
-
-
33846502114
-
Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies
-
[117] Subra, C., Laulagnier, K., Perret, B., Record, M., Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies. Biochimie 89 (2007), 205–212.
-
(2007)
Biochimie
, vol.89
, pp. 205-212
-
-
Subra, C.1
Laulagnier, K.2
Perret, B.3
Record, M.4
-
118
-
-
0013495952
-
Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation
-
[118] Wubbolts, R., Leckie, R.S., Veenhuizen, P.T., Schwarzmann, G., Mobius, W., Hoernschemeyer, J., Slot, J.W., Geuze, H.J., Stoorvogel, W., Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation. J. Biol. Chem. 278 (2003), 10963–10972.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10963-10972
-
-
Wubbolts, R.1
Leckie, R.S.2
Veenhuizen, P.T.3
Schwarzmann, G.4
Mobius, W.5
Hoernschemeyer, J.6
Slot, J.W.7
Geuze, H.J.8
Stoorvogel, W.9
-
119
-
-
33646146422
-
Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery
-
[119] Ratajczak, J., Miekus, K., Kucia, M., Zhang, J., Reca, R., Dvorak, P., Ratajczak, M.Z., Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia 20 (2006), 847–856.
-
(2006)
Leukemia
, vol.20
, pp. 847-856
-
-
Ratajczak, J.1
Miekus, K.2
Kucia, M.3
Zhang, J.4
Reca, R.5
Dvorak, P.6
Ratajczak, M.Z.7
-
120
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
[120] Valadi, H., Ekstrom, K., Bossios, A., Sjostrand, M., Lee, J.J., Lotvall, J.O., Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat. Cell Biol. 9 (2007), 654–659.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekstrom, K.2
Bossios, A.3
Sjostrand, M.4
Lee, J.J.5
Lotvall, J.O.6
-
121
-
-
77950889558
-
Functional delivery of viral miRNAs via exosomes
-
[121] Pegtel, D.M., Cosmopoulos, K., Thorley-Lawson, D.A., van Eijndhoven, M.A., Hopmans, E.S., Lindenberg, J.L., de Gruijl, T.D., Wurdinger, T., Middeldorp, J.M., Functional delivery of viral miRNAs via exosomes. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 6328–6333.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 6328-6333
-
-
Pegtel, D.M.1
Cosmopoulos, K.2
Thorley-Lawson, D.A.3
van Eijndhoven, M.A.4
Hopmans, E.S.5
Lindenberg, J.L.6
de Gruijl, T.D.7
Wurdinger, T.8
Middeldorp, J.M.9
-
122
-
-
84862908547
-
Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
-
[122] Montecalvo, A., Larregina, A.T., Shufesky, W.J., Stolz, D.B., Sullivan, M.L., Karlsson, J.M., Baty, C.J., Gibson, G.A., Erdos, G., Wang, Z., Milosevic, J., Tkacheva, O.A., Divito, S.J., Jordan, R., Lyons-Weiler, J., Watkins, S.C., Morelli, A.E., Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood 119 (2012), 756–766.
-
(2012)
Blood
, vol.119
, pp. 756-766
-
-
Montecalvo, A.1
Larregina, A.T.2
Shufesky, W.J.3
Stolz, D.B.4
Sullivan, M.L.5
Karlsson, J.M.6
Baty, C.J.7
Gibson, G.A.8
Erdos, G.9
Wang, Z.10
Milosevic, J.11
Tkacheva, O.A.12
Divito, S.J.13
Jordan, R.14
Lyons-Weiler, J.15
Watkins, S.C.16
Morelli, A.E.17
-
123
-
-
85016304525
-
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood
-
[123] Cheng, L., Sharples, R.A., Scicluna, B.J., Hill, A.F., Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood. J. Extracell. Vesicles, 3, 2014.
-
(2014)
J. Extracell. Vesicles
, vol.3
-
-
Cheng, L.1
Sharples, R.A.2
Scicluna, B.J.3
Hill, A.F.4
-
124
-
-
84905485531
-
Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine
-
[124] Cheng, L., Sun, X., Scicluna, B.J., Coleman, B.M., Hill, A.F., Characterization and deep sequencing analysis of exosomal and non-exosomal miRNA in human urine. Kidney Int. 86 (2014), 433–444.
-
(2014)
Kidney Int.
, vol.86
, pp. 433-444
-
-
Cheng, L.1
Sun, X.2
Scicluna, B.J.3
Coleman, B.M.4
Hill, A.F.5
-
125
-
-
84870599244
-
Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
-
[125] Bellingham, S.A., Coleman, B.M., Hill, A.F., Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells. Nucleic Acids Res. 40 (2012), 10937–10949.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 10937-10949
-
-
Bellingham, S.A.1
Coleman, B.M.2
Hill, A.F.3
-
126
-
-
84872704002
-
Exosome can prevent RNase from degrading microRNA in feces
-
[126] Koga, Y., Yasunaga, M., Moriya, Y., Akasu, T., Fujita, S., Yamamoto, S., Matsumura, Y., Exosome can prevent RNase from degrading microRNA in feces. J. Gastrointest. Oncol. 2 (2011), 215–222.
-
(2011)
J. Gastrointest. Oncol.
, vol.2
, pp. 215-222
-
-
Koga, Y.1
Yasunaga, M.2
Moriya, Y.3
Akasu, T.4
Fujita, S.5
Yamamoto, S.6
Matsumura, Y.7
-
127
-
-
84873438103
-
Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells
-
[127] Haqqani, A.S., Delaney, C.E., Tremblay, T.L., Sodja, C., Sandhu, J.K., Stanimirovic, D.B., Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells. Fluids Barriers CNS, 10, 2013, 4.
-
(2013)
Fluids Barriers CNS
, vol.10
, pp. 4
-
-
Haqqani, A.S.1
Delaney, C.E.2
Tremblay, T.L.3
Sodja, C.4
Sandhu, J.K.5
Stanimirovic, D.B.6
-
128
-
-
84866426167
-
Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?
-
[128] Bellingham, S.A., Guo, B.B., Coleman, B.M., Hill, A.F., Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?. Front. Physiol., 3, 2012, 124.
-
(2012)
Front. Physiol.
, vol.3
, pp. 124
-
-
Bellingham, S.A.1
Guo, B.B.2
Coleman, B.M.3
Hill, A.F.4
-
129
-
-
80053309537
-
Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth
-
[129] Kogure, T., Lin, W.L., Yan, I.K., Braconi, C., Patel, T., Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth. Hepatology 54 (2011), 1237–1248.
-
(2011)
Hepatology
, vol.54
, pp. 1237-1248
-
-
Kogure, T.1
Lin, W.L.2
Yan, I.K.3
Braconi, C.4
Patel, T.5
-
130
-
-
23944514849
-
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation
-
[130] Bagga, S., Bracht, J., Hunter, S., Massirer, K., Holtz, J., Eachus, R., Pasquinelli, A.E., Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 122 (2005), 553–563.
-
(2005)
Cell
, vol.122
, pp. 553-563
-
-
Bagga, S.1
Bracht, J.2
Hunter, S.3
Massirer, K.4
Holtz, J.5
Eachus, R.6
Pasquinelli, A.E.7
-
131
-
-
0036544755
-
Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation
-
[131] Lai, E.C., Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. Nat. Genet. 30 (2002), 363–364.
-
(2002)
Nat. Genet.
, vol.30
, pp. 363-364
-
-
Lai, E.C.1
-
132
-
-
40449124713
-
MicroRNA expression in the adult mouse central nervous system
-
[132] Bak, M., Silahtaroglu, A., Moller, M., Christensen, M., Rath, M.F., Skryabin, B., Tommerup, N., Kauppinen, S., MicroRNA expression in the adult mouse central nervous system. RNA 14 (2008), 432–444.
-
(2008)
RNA
, vol.14
, pp. 432-444
-
-
Bak, M.1
Silahtaroglu, A.2
Moller, M.3
Christensen, M.4
Rath, M.F.5
Skryabin, B.6
Tommerup, N.7
Kauppinen, S.8
-
133
-
-
1942494040
-
Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
-
[133] Sempere, L.F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., Ambros, V., Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol., 5, 2004, R13.
-
(2004)
Genome Biol.
, vol.5
, pp. R13
-
-
Sempere, L.F.1
Freemantle, S.2
Pitha-Rowe, I.3
Moss, E.4
Dmitrovsky, E.5
Ambros, V.6
-
134
-
-
43949124669
-
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
-
[134] Stark, K.L., Xu, B., Bagchi, A., Lai, W.S., Liu, H., Hsu, R., Wan, X., Pavlidis, P., Mills, A.A., Karayiorgou, M., Gogos, J.A., Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat. Genet. 40 (2008), 751–760.
-
(2008)
Nat. Genet.
, vol.40
, pp. 751-760
-
-
Stark, K.L.1
Xu, B.2
Bagchi, A.3
Lai, W.S.4
Liu, H.5
Hsu, R.6
Wan, X.7
Pavlidis, P.8
Mills, A.A.9
Karayiorgou, M.10
Gogos, J.A.11
-
135
-
-
70349233931
-
Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease
-
[135] Montag, J., Hitt, R., Opitz, L., Schulz-Schaeffer, W.J., Hunsmann, G., Motzkus, D., Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease. Mol. Neurodegener., 4, 2009, 36.
-
(2009)
Mol. Neurodegener.
, vol.4
, pp. 36
-
-
Montag, J.1
Hitt, R.2
Opitz, L.3
Schulz-Schaeffer, W.J.4
Hunsmann, G.5
Motzkus, D.6
-
136
-
-
56649112767
-
A miRNA signature of prion induced neurodegeneration
-
[136] Saba, R., Goodman, C.D., Huzarewich, R.L.C.H., Robertson, C., Booth, S.A., A miRNA signature of prion induced neurodegeneration. PLoS One, 3, 2008, e3652.
-
(2008)
PLoS One
, vol.3
, pp. e3652
-
-
Saba, R.1
Goodman, C.D.2
Huzarewich, R.L.C.H.3
Robertson, C.4
Booth, S.A.5
-
137
-
-
84857154347
-
MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state
-
[137] Saba, R., Gushue, S., Huzarewich, R.L., Manguiat, K., Medina, S., Robertson, C., Booth, S.A., MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state. PloS One, 7, 2012, e30832.
-
(2012)
PloS One
, vol.7
, pp. e30832
-
-
Saba, R.1
Gushue, S.2
Huzarewich, R.L.3
Manguiat, K.4
Medina, S.5
Robertson, C.6
Booth, S.A.7
-
138
-
-
84870847550
-
Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice
-
[138] Majer, A., Medina, S.J., Niu, Y., Abrenica, B., Manguiat, K.J., Frost, K.L., Philipson, C.S., Sorensen, D.L., Booth, S.A., Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected mice. PLoS Pathog., 8, 2012, e1003002.
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1003002
-
-
Majer, A.1
Medina, S.J.2
Niu, Y.3
Abrenica, B.4
Manguiat, K.J.5
Frost, K.L.6
Philipson, C.S.7
Sorensen, D.L.8
Booth, S.A.9
-
139
-
-
29244449320
-
Correlative studies support lipid peroxidation is linked to PrP(res) propagation as an early primary pathogenic event in prion disease
-
[139] Brazier, M.W., Lewis, V., Ciccotosto, G.D., Klug, G.M., Lawson, V.A., Cappai, R., Ironside, J.W., Masters, C.L., Hill, A.F., White, A.R., Collins, S., Correlative studies support lipid peroxidation is linked to PrP(res) propagation as an early primary pathogenic event in prion disease. Brain Res. Bull. 68 (2006), 346–354.
-
(2006)
Brain Res. Bull.
, vol.68
, pp. 346-354
-
-
Brazier, M.W.1
Lewis, V.2
Ciccotosto, G.D.3
Klug, G.M.4
Lawson, V.A.5
Cappai, R.6
Ironside, J.W.7
Masters, C.L.8
Hill, A.F.9
White, A.R.10
Collins, S.11
-
140
-
-
77955599311
-
miRNA malfunction causes spinal motor neuron disease
-
[140] Haramati, S., Chapnik, E., Sztainberg, Y., Eilam, R., Zwang, R., Gershoni, N., McGlinn, E., Heiser, P.W., Wills, A.M., Wirguin, I., Rubin, L.L., Misawa, H., Tabin, C.J., Brown, R. Jr., Chen, A., Hornstein, E., miRNA malfunction causes spinal motor neuron disease. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 13111–13116.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 13111-13116
-
-
Haramati, S.1
Chapnik, E.2
Sztainberg, Y.3
Eilam, R.4
Zwang, R.5
Gershoni, N.6
McGlinn, E.7
Heiser, P.W.8
Wills, A.M.9
Wirguin, I.10
Rubin, L.L.11
Misawa, H.12
Tabin, C.J.13
Brown, R.14
Chen, A.15
Hornstein, E.16
-
141
-
-
77952675535
-
MicroRNAs and deregulated gene expression networks in neurodegeneration
-
[141] Sonntag, K.C., MicroRNAs and deregulated gene expression networks in neurodegeneration. Brain Res. 1338 (2010), 48–57.
-
(2010)
Brain Res.
, vol.1338
, pp. 48-57
-
-
Sonntag, K.C.1
-
142
-
-
42149186322
-
Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes
-
[142] Sorensen, G., Medina, S., Parchaliuk, D., Phillipson, C., Robertson, C., Booth, S.A., Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes. BMC Genom., 9, 2008, 114.
-
(2008)
BMC Genom.
, vol.9
, pp. 114
-
-
Sorensen, G.1
Medina, S.2
Parchaliuk, D.3
Phillipson, C.4
Robertson, C.5
Booth, S.A.6
-
143
-
-
84864282232
-
Exosomes in neurological disease
-
[143] Hill, A.F., Exosomes in neurological disease. Curr. Med. Lit. Neurol. 25 (2009), 27–32.
-
(2009)
Curr. Med. Lit. Neurol.
, vol.25
, pp. 27-32
-
-
Hill, A.F.1
-
144
-
-
78651372944
-
Prion disease induced alterations in gene expression in spleen and brain prior to clinical symptoms
-
[144] Kim, H.O., Snyder, G.P., Blazey, T.M., Race, R.E., Chesebro, B., Skinner, P.J., Prion disease induced alterations in gene expression in spleen and brain prior to clinical symptoms. Adv. Appl. Bioinform. Chem. AABC 1 (2008), 29–50.
-
(2008)
Adv. Appl. Bioinform. Chem. AABC
, vol.1
, pp. 29-50
-
-
Kim, H.O.1
Snyder, G.P.2
Blazey, T.M.3
Race, R.E.4
Chesebro, B.5
Skinner, P.J.6
-
145
-
-
8844252438
-
Molecular classification of scrapie strains in mice using gene expression profiling
-
[145] Booth, S., Bowman, C., Baumgartner, R., Dolenko, B., Sorensen, G., Robertson, C., Coulthart, M., Phillipson, C., Somorjai, R., Molecular classification of scrapie strains in mice using gene expression profiling. Biochem. Biophys. Res. Commun. 325 (2004), 1339–1345.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.325
, pp. 1339-1345
-
-
Booth, S.1
Bowman, C.2
Baumgartner, R.3
Dolenko, B.4
Sorensen, G.5
Robertson, C.6
Coulthart, M.7
Phillipson, C.8
Somorjai, R.9
-
146
-
-
33745092824
-
Gene expression alterations in brains of mice infected with three strains of scrapie
-
[146] Skinner, P.J., Abbassi, H., Chesebro, B., Race, R.E., Reilly, C., Haase, A.T., Gene expression alterations in brains of mice infected with three strains of scrapie. BMC Genom., 7, 2006, 114.
-
(2006)
BMC Genom.
, vol.7
, pp. 114
-
-
Skinner, P.J.1
Abbassi, H.2
Chesebro, B.3
Race, R.E.4
Reilly, C.5
Haase, A.T.6
-
147
-
-
0037868952
-
Single-cell microarray analysis in hippocampus CA1: demonstration and validation of cellular heterogeneity
-
[147] Kamme, F., Salunga, R., Yu, J., Tran, D.T., Zhu, J., Luo, L., Bittner, A., Guo, H.Q., Miller, N., Wan, J., Erlander, M., Single-cell microarray analysis in hippocampus CA1: demonstration and validation of cellular heterogeneity. J. Neurosci. Off. J. Soc. Neurosci. 23 (2003), 3607–3615.
-
(2003)
J. Neurosci. Off. J. Soc. Neurosci.
, vol.23
, pp. 3607-3615
-
-
Kamme, F.1
Salunga, R.2
Yu, J.3
Tran, D.T.4
Zhu, J.5
Luo, L.6
Bittner, A.7
Guo, H.Q.8
Miller, N.9
Wan, J.10
Erlander, M.11
-
148
-
-
79960963456
-
Neuronal type-specific gene expression profiling and laser-capture microdissection
-
[148] Pietersen, C.Y., Lim, M.P., Macey, L., Woo, T.U., Sonntag, K.C., Neuronal type-specific gene expression profiling and laser-capture microdissection. Methods Mol. Biol. 755 (2011), 327–343.
-
(2011)
Methods Mol. Biol.
, vol.755
, pp. 327-343
-
-
Pietersen, C.Y.1
Lim, M.P.2
Macey, L.3
Woo, T.U.4
Sonntag, K.C.5
-
149
-
-
84904215335
-
Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked
-
[149] Sandberg, M.K., Al-Doujaily, H., Sharps, B., De Oliveira, M.W., Schmidt, C., Richard-Londt, A., Lyall, S., Linehan, J.M., Brandner, S., Wadsworth, J.D., Clarke, A.R., Collinge, J., Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked. Nat. Commun., 5, 2014, 4347.
-
(2014)
Nat. Commun.
, vol.5
, pp. 4347
-
-
Sandberg, M.K.1
Al-Doujaily, H.2
Sharps, B.3
De Oliveira, M.W.4
Schmidt, C.5
Richard-Londt, A.6
Lyall, S.7
Linehan, J.M.8
Brandner, S.9
Wadsworth, J.D.10
Clarke, A.R.11
Collinge, J.12
|