Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrPSc) into contiguous membranes

EMBO Journal

Volumn 21, Issue 5, 2002, Pages 1031-1040

  Baron, Gerald S ^a   Wehrly, Kathy ^a   Dorward, David W ^a   Chesebro, Bruce ^a   Caughey, Byron ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Microsomes; PEG; PI PLC; PrP; Raft

Indexed keywords

ACID; DETERGENT; GLYCOSYLPHOSPHATIDYLINOSITOL; ISOPROTEIN; MACROGOL; MEMBRANE PROTEIN; PHOSPHOLIPASE C; PRION PROTEIN; PROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MICROSOME; CELL FREE SYSTEM; CONTROLLED STUDY; ENDOSOME; LIPID MEMBRANE; LYSOSOME; MEMBRANE BINDING; MEMBRANE FUSION; MOUSE; NONHUMAN; PH; PRION DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; PROTEIN STABILITY; SCRAPIE AGENT; TARGET CELL;

ANIMALS; CELL MEMBRANE; CELL-FREE SYSTEM; DRUG RESISTANCE; ENDOPEPTIDASES; GLYCOSYLPHOSPHATIDYLINOSITOLS; HYDROGEN-ION CONCENTRATION; MEMBRANE FUSION; MEMBRANE MICRODOMAINS; MICE; MICROSOMES; NEUROBLASTOMA; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE; PHOSPHOLIPASE C; POLYETHYLENE GLYCOLS; PROTEIN ISOFORMS; PRPSC PROTEINS; RECOMBINANT FUSION PROTEINS; SCRAPIE; TUMOR CELLS, CULTURED;

ANIMALIA; INSERTION SEQUENCES; SCRAPIE PRION;

EID: 0036500554     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/21.5.1031     Document Type: Article

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