DNA Targeting by a Minimal CRISPR RNA-Guided Cascade

Molecular Cell

Volumn 63, Issue 5, 2016, Pages 840-851

  Hochstrasser, Megan L ^a   Taylor, David W ^a,b   Kornfeld, Jack E ^a   Nogales, Eva ^a,b,c   Doudna, Jennifer A ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BINDING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONFORMATIONAL TRANSITION; CRYOELECTRON MICROSCOPY; DNA BINDING; DNA STRAND; GENE TARGETING; STRUCTURE ACTIVITY RELATION; ALPHA HELIX; BINDING SITE; CHEMISTRY; CONFORMATION; CRISPR CAS SYSTEM; DESULFOVIBRIO VULGARIS; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE EDITING; GENE EXPRESSION; GENETICS; KINETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR MODEL; OPERON; PROTEIN DOMAIN; PROTEIN MOTIF;

BACTERIAL PROTEIN; BACTERIAL RNA; DNA; ENDONUCLEASE; GUIDE RNA; PROTEIN BINDING; RECOMBINANT PROTEIN;

AMINO ACID MOTIFS; BACTERIAL PROTEINS; BINDING SITES; CLONING, MOLECULAR; CRISPR-CAS SYSTEMS; CRYOELECTRON MICROSCOPY; DESULFOVIBRIO VULGARIS; DNA; ENDONUCLEASES; ESCHERICHIA COLI; GENE EDITING; GENE EXPRESSION; KINETICS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OPERON; PROTEIN BINDING; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT PROTEINS; RNA, BACTERIAL; RNA, GUIDE; SUBSTRATE SPECIFICITY;

EID: 84992450228     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.07.027     Document Type: Article

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