Two distinct DNA binding modes guide dual roles of a CRISPR-cas protein complex

Molecular Cell

Volumn 58, Issue 1, 2015, Pages 60-70

  Blosser, Timothy R ^a,c   Loeff, Luuk ^a   Westra, Edze R ^b,d   Vlot, Marnix ^b   Künne, Tim ^b   Sobota, Małgorzata ^b   Dekker, Cees ^a   Brouns, Stan J J ^b   Joo, Chirlmin ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; DNA; TENIDAP; ESCHERICHIA COLI PROTEIN; PROTEIN BINDING; VIRUS DNA;

ARTICLE; BACTERIAL IMMUNITY; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CRISPR CAS SYSTEM; DNA BINDING; DNA CONFORMATION; ENZYME MECHANISM; ESCHERICHIA COLI; GENE MUTATION; IN VIVO STUDY; MOLECULAR RECOGNITION; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN INTERACTION; REGULATORY MECHANISM; CHEMISTRY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COLIPHAGE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; VIROLOGY;

PROKARYOTA;

BASE SEQUENCE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; COLIPHAGES; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA, VIRAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING;

EID: 84926226607     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.01.028     Document Type: Article

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