Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning

Science

Volumn 348, Issue 6234, 2015, Pages 581-585

  Taylor, David W ^a,b   Zhu, Yifan ^c   Staals, Raymond H J ^c,g   Kornfeld, Jack E ^a   Shinkai, Akeo ^d,e   Van Der Oost, John ^c   Nogales, Eva ^a,b,f   Doudna, Jennifer A ^a,b,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d RIKEN SPring 8 Center   (Japan)

^e RIKEN   (Japan)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^g UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT RNA; DOUBLE STRANDED DNA; GUIDE RNA; RNA; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; MULTIPROTEIN COMPLEX;

ADAPTATION; BACTERIUM; COMMON ANCESTRY; DIVERGENCE; IMMUNE SYSTEM; IMMUNITY; PROTEIN; RNA;

ARTICLE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONFORMATIONAL TRANSITION; CRISPR CAS SYSTEM; CRISPR RAMP MODULE COMPLEX; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; DNA HELIX; DNA STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PYROCOCCUS FURIOSUS; RNA DEGRADATION; THERMUS THERMOPHILUS; TYPE III SECRETION SYSTEM; CHEMISTRY; IMMUNOLOGY; RNA CLEAVAGE; ULTRASTRUCTURE;

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRYOELECTRON MICROSCOPY; MULTIPROTEIN COMPLEXES; RNA; RNA CLEAVAGE; THERMUS THERMOPHILUS;

EID: 84929493523     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa4535     Document Type: Article

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