E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1

Nature Immunology

Volumn 17, Issue 12, 2016, Pages 1342-1351

  Song, Guanhua ^a,b   Liu, Bingyu ^a   Li, Zhihui ^b   Wu, Haifeng ^a   Wang, Peng ^a   Zhao, Kai ^a   Jiang, Guosheng ^b   Zhang, Lei ^a   Gao, Chengjiang ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; PROTEIN KINASE; PROTEIN RNF128; TANK BINDING KINASE 1; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; IRF3 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; RNF128 PROTEIN, HUMAN; RNF128 PROTEIN, MOUSE; SMALL INTERFERING RNA; TBK1 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; FEMALE; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFECTION SENSITIVITY; INNATE IMMUNITY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; UBIQUITINATION; VESICULOVIRUS; VIRUS INFECTION; ANIMAL; C57BL MOUSE; GENETICS; HEK293 CELL LINE; HERPES SIMPLEX; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; SIGNAL TRANSDUCTION; VESICULAR STOMATITIS; VIROLOGY;

ANIMALS; FEMALE; HEK293 CELLS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VESICULAR STOMATITIS; VESICULOVIRUS;

EID: 84992420722     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3588     Document Type: Article

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