Grail controls Th2 cell development by targeting STAT6 for degradation

Nature Communications

Volumn 5, Issue , 2014, Pages

  Sahoo, Anupama ^a   Alekseev, Andrei ^a   Obertas, Lidiya ^a   Nurieva, Roza ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 4; STAT6 PROTEIN; TRANSCRIPTION FACTOR GATA 3; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE E3 GRAIL; UNCLASSIFIED DRUG; GATA3 PROTEIN, MOUSE; GRAIL PROTEIN; STAT6 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ALLERGY; ASTHMA; BIOLOGICAL ANALYSIS; ENZYME ACTIVITY; GENE EXPRESSION;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEGRADATION KINETICS; DISEASE PREDISPOSITION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PROMOTER REGION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TH2 CELL; TRANSACTIVATION; UBIQUITINATION; ANIMAL; ASTHMA; C57BL MOUSE; CELL DIFFERENTIATION; DRUG EFFECTS; FEEDBACK SYSTEM; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ASTHMA; CELL DIFFERENTIATION; FEEDBACK, PHYSIOLOGICAL; GATA3 TRANSCRIPTION FACTOR; HEK293 CELLS; HUMANS; INTERLEUKIN-4; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; STAT6 TRANSCRIPTION FACTOR; TH2 CELLS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84907333535     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5732     Document Type: Article

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