TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1

Journal of Experimental Medicine

Volumn 209, Issue 10, 2012, Pages 1703-1711

  Zhang, Meng ^a   Wang, Lijuan ^a   Zhao, Xueying ^a   Zhao, Kai ^a   Meng, Hong ^b   Zhao, Wei ^a   Gao, Chengjiang ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; PHOSPHOTRANSFERASE; PROTEASOME; REGULATOR PROTEIN; RETINOIC ACID INDUCIBLE PROTEIN I; TANK BINDING KINASE 1; TNF RECEPTOR ASSOCIATED FACTOR INTERACTING PROTEIN; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME DEGRADATION; ENZYME REGULATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; VESICULAR STOMATITIS VIRUS; VIRUS REPLICATION;

ANIMALS; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MACROPHAGES, PERITONEAL; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; RNA INTERFERENCE; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS; UBIQUITINATION;

EID: 84868554937     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20120024     Document Type: Article

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