TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3

PLoS Pathogens

Volumn 11, Issue 3, 2015, Pages 1-22

  Wang, Peng ^a   Zhao, Wei ^a   Zhao, Kai ^a   Zhang, Lei ^a   Gao, Chengjiang ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; PEPTIDES AND PROTEINS; PROTEASOME; RIG I LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TRIPARTITE MOTIF PROTEIN 26; UNCLASSIFIED DRUG; IRF3 PROTEIN, MOUSE; TRIM26 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL RESPONSE; ARTICLE; BINDING ASSAY; CONTROLLED STUDY; DNA SEQUENCE; ENZYMATIC DEGRADATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING; LUCIFERASE ASSAY; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PLASMID; PROMOTER REGION; PROTON TRANSPORT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; UBIQUITINATION; VIRUS INFECTION; VIRUS REPLICATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL NUCLEUS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY; METABOLISM; RHABDOVIRUS INFECTION; TRANSGENIC MOUSE; VESICULOVIRUS;

MUS MUSCULUS;

ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHABDOVIRIDAE INFECTIONS; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VESICULOVIRUS;

EID: 84926469650     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004726     Document Type: Article

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