Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury

Cell Metabolism

Volumn 24, Issue 4, 2016, Pages 582-592

  Brand, Martin D ^a   Goncalves, Renata L S ^a,d   Orr, Adam L ^a,e   Vargas, Leonardo ^b   Gerencser, Akos A ^a   Borch Jensen, Martin ^a   Wang, Yves T ^c   Melov, Simon ^a   Turk, Carolina N ^b   Matzen, Jason T ^b   Dardov, Victoria J ^b   Petrassi, H Michael ^b   Meeusen, Shelly L ^b   Perevoshchikova, Irina V ^a,f   Jasper, Heinrich ^a   Brookes, Paul S ^c   Ainscow, Edward K ^b  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e GLADSTONE INSTITUTES   (United States)

^f BIOMARIN PHARMACEUTICAL INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITATE HYDRATASE; ANTIOXIDANT; CASPASE; HYDROGEN PEROXIDE; PROTECTIVE AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; SUPPRESSORS OF SITE IQ ELECTRON LEAK; UNCLASSIFIED DRUG; CASPASE 3; CASPASE 7; SUPEROXIDE; TUNICAMYCIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE CULTURE; CELL HYPERPLASIA; CELLULAR STRESS SIGNAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ELECTRON TRANSPORT; ENDOPLASMIC RETICULUM STRESS; ENERGY METABOLISM; ENZYME ACTIVATION; FEMALE; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEK293 CELL LINE; HIGH THROUGHPUT SCREENING; IN VIVO STUDY; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN TENSION; PRIORITY JOURNAL; REPERFUSION INJURY; STEM CELL; ANIMAL; ASTROCYTE; CELL CULTURE; CELL PROLIFERATION; CELL PROTECTION; CYTOLOGY; DROSOPHILA; DRUG EFFECTS; HEART; HYPERPLASIA; INTESTINE; METABOLISM; MUSCLE MITOCHONDRION; OXIDATIVE STRESS; PATHOLOGY; PERFUSION; RAT;

ANIMALS; ASTROCYTES; CASPASE 3; CASPASE 7; CELL PROLIFERATION; CELLS, CULTURED; CYTOPROTECTION; DROSOPHILA; ELECTRON TRANSPORT COMPLEX I; HEART; HYDROGEN PEROXIDE; HYPERPLASIA; INTESTINES; MICE; MITOCHONDRIA, MUSCLE; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PERFUSION; RATS; REPERFUSION INJURY; STEM CELLS; SUPEROXIDES; TUNICAMYCIN;

EID: 84992390935     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.08.012     Document Type: Article

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