Mitochondrial defect drives non-autonomous tumour progression through Hippo signalling in Drosophila

Nature

Volumn 490, Issue 7421, 2012, Pages 547-551

  Ohsawa, Shizue ^a   Sato, Yoshitaka ^a   Enomoto, Masato ^a   Nakamura, Mai ^a   Betsumiya, Aya ^a   Igaki, Tatsushi ^a,b  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HIPPO PROTEIN; PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; WNT1 PROTEIN;

CANCER; MITOCHONDRIAL DNA; SIGNAL; TUMOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DROSOPHILA; ENZYME ACTIVATION; EPITHELIUM; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR GROWTH; UPREGULATION;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CLONE CELLS; COMPOUND EYE, ARTHROPOD; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; IMAGINAL DISCS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOCHONDRIA; NEOPLASMS; ONCOGENE PROTEIN P21(RAS); OXIDATIVE STRESS; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UP-REGULATION; WNT1 PROTEIN;

EID: 84867853849     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11452     Document Type: Article

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