Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex

Free Radical Biology and Medicine

Volumn 91, Issue , 2016, Pages 247-255

  Goncalves, Renata L S ^a,c   Bunik, Victoria I ^b   Brand, Martin D ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

2 Oxoacid dehydrogenase complexes; 2 Oxoadipic acid dehydrogenase; DHTKD1; Reactive oxygen species; ROS; Skeletal muscle mitochondria

Indexed keywords

2 OXOGLUTARIC ACID; 2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; HYDROGEN PEROXIDE; LYSINE; OXOGLUTARATE DEHYDROGENASE; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SUPEROXIDE; TRYPTOPHAN; ADIPIC ACID DERIVATIVE; ALPHA-KETOADIPIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DECARBOXYLATION; ENZYME MECHANISM; FEMALE; MITOCHONDRION; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SKELETAL MUSCLE; ANIMAL; ENZYMOLOGY; KINETICS; METABOLISM; MUSCLE MITOCHONDRION; OXIDATION REDUCTION REACTION; PHYSIOLOGY; WISTAR RAT;

ADIPATES; ANIMALS; FEMALE; HYDROGEN PEROXIDE; KETOGLUTARATE DEHYDROGENASE COMPLEX; KINETICS; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; OXIDATION-REDUCTION; RATS, WISTAR; SUPEROXIDES;

EID: 84952342515     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.12.020     Document Type: Article

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