-
1
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004; 306: 457-461.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
-
2
-
-
84870218967
-
Hepatic mitochondrial dysfunction induced by fatty acids and ethanol
-
Gyamfi D, Everitt HE, Tewfik I, Clemens DL, Patel VB. Hepatic mitochondrial dysfunction induced by fatty acids and ethanol. Free Radic Biol Med 2012; 53: 2131-2145.
-
(2012)
Free Radic Biol Med
, vol.53
, pp. 2131-2145
-
-
Gyamfi, D.1
Everitt, H.E.2
Tewfik, I.3
Clemens, D.L.4
Patel, V.B.5
-
3
-
-
84864198388
-
A liver full of JNK: Signaling in regulation of cell function and disease pathogenesis, and clinical approaches
-
Seki E, Brenner DA, Karin M. A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology 2012; 143: 307-320.
-
(2012)
Gastroenterology
, vol.143
, pp. 307-320
-
-
Seki, E.1
Brenner, D.A.2
Karin, M.3
-
4
-
-
46649084880
-
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury
-
Hanawa N, Shinohara M, Saberi B, Gaarde WA, Han D, Kaplowitz N. Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury. J Biol Chem 2008; 283: 13565-13577.
-
(2008)
J Biol Chem
, vol.283
, pp. 13565-13577
-
-
Hanawa, N.1
Shinohara, M.2
Saberi, B.3
Gaarde, W.A.4
Han, D.5
Kaplowitz, N.6
-
5
-
-
80053425902
-
C-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice
-
Win S, Than TA, Han D, Petrovic LM, Kaplowitz N. c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice. J Biol Chem 2011; 286: 35071-35078.
-
(2011)
J Biol Chem
, vol.286
, pp. 35071-35078
-
-
Win, S.1
Than, T.A.2
Han, D.3
Petrovic, L.M.4
Kaplowitz, N.5
-
6
-
-
84873681976
-
Inhibition of JNK mitochondrial localization and signaling is protective against ischemia/reperfusion injury in rats
-
Chambers JW, Pachori A, Howard S, Iqbal S, LoGrasso PV. Inhibition of JNK mitochondrial localization and signaling is protective against ischemia/reperfusion injury in rats. J Biol Chem 2013; 288: 4000-4011.
-
(2013)
J Biol Chem
, vol.288
, pp. 4000-4011
-
-
Chambers, J.W.1
Pachori, A.2
Howard, S.3
Iqbal, S.4
Lograsso, P.V.5
-
7
-
-
84872356254
-
Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo
-
Chambers JW, Howard S, LoGrasso PV. Blocking c-Jun N-terminal kinase (JNK) translocation to the mitochondria prevents 6-hydroxydopamine-induced toxicity in vitro and in vivo. J Biol Chem 2013; 288: 1079-1087.
-
(2013)
J Biol Chem
, vol.288
, pp. 1079-1087
-
-
Chambers, J.W.1
Howard, S.2
Lograsso, P.V.3
-
8
-
-
33750440743
-
ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1
-
Shiraishi H, Okamoto H, Yoshimura A, Yoshida H. ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1. J Cell Sci 2006; 119: 3958-3966.
-
(2006)
J Cell Sci
, vol.119
, pp. 3958-3966
-
-
Shiraishi, H.1
Okamoto, H.2
Yoshimura, A.3
Yoshida, H.4
-
9
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
Tabas I, Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol 2011; 13: 184-190.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
10
-
-
0036312001
-
Endoplasmic reticulum stressinduced cell death requires mitochondrial membrane permeabilization
-
Boya P, Cohen I, Zamzami N, Vieira HL, Kroemer G. Endoplasmic reticulum stressinduced cell death requires mitochondrial membrane permeabilization. Cell Death Differ 2002; 9: 465-467.
-
(2002)
Cell Death Differ
, vol.9
, pp. 465-467
-
-
Boya, P.1
Cohen, I.2
Zamzami, N.3
Vieira, H.L.4
Kroemer, G.5
-
11
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP et al. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 2000; 287: 664-666.
-
(2000)
Science
, vol.287
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
-
12
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K et al. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 2002; 16: 1345-1355.
-
(2002)
Genes Dev
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
-
13
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R et al. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 2004; 18: 3066-3077.
-
(2004)
Genes Dev
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
-
15
-
-
70349696241
-
Calcium/calmodulindependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways
-
Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J et al. Calcium/calmodulindependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. J Clin Invest 2009; 119: 2925-2941.
-
(2009)
J Clin Invest
, vol.119
, pp. 2925-2941
-
-
Timmins, J.M.1
Ozcan, L.2
Seimon, T.A.3
Li, G.4
Malagelada, C.5
Backs, J.6
-
16
-
-
84855696465
-
MTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway
-
Kato H, Nakajima S, Saito Y, Takahashi S, Katoh R, Kitamura M. mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway. Cell Death Differ 2012; 19: 310-320.
-
(2012)
Cell Death Differ
, vol.19
, pp. 310-320
-
-
Kato, H.1
Nakajima, S.2
Saito, Y.3
Takahashi, S.4
Katoh, R.5
Kitamura, M.6
-
17
-
-
70349905357
-
Role of ERO1-alphamediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis
-
Li G, Mongillo M, Chin KT, Harding H, Ron D, Marks AR et al. Role of ERO1-alphamediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis. J Cell Biol 2009; 186: 783-792.
-
(2009)
J Cell Biol
, vol.186
, pp. 783-792
-
-
Li, G.1
Mongillo, M.2
Chin, K.T.3
Harding, H.4
Ron, D.5
Marks, A.R.6
-
18
-
-
80051704067
-
The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load
-
Chin KT, Kang G, Qu J, Gardner LB, Coetzee WA, Zito E et al. The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load. FASEB J 2011; 25: 2583-2591.
-
(2011)
FASEB J
, vol.25
, pp. 2583-2591
-
-
Chin, K.T.1
Kang, G.2
Qu, J.3
Gardner, L.B.4
Coetzee, W.A.5
Zito, E.6
-
19
-
-
0020643801
-
2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate
-
2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature 1983; 306: 67-69.
-
(1983)
Nature
, vol.306
, pp. 67-69
-
-
Streb, H.1
Irvine, R.F.2
Berridge, M.J.3
Schulz, I.4
-
20
-
-
0030724177
-
Tunicamycin increases intracellular calcium levels in bovine aortic endothelial cells
-
Buckley BJ, Whorton AR. Tunicamycin increases intracellular calcium levels in bovine aortic endothelial cells. Am J Physiol 1997; 273: 1298-1305.
-
(1997)
Am J Physiol
, vol.273
, pp. 1298-1305
-
-
Buckley, B.J.1
Whorton, A.R.2
-
21
-
-
33749022800
-
Structural and functional features and significance of the physical linkage between ER and mitochondria
-
Csordás G, Renken C, Várnai P, Walter L, Weaver D, Buttle KF et al. Structural and functional features and significance of the physical linkage between ER and mitochondria. J Cell Biol 2006; 174: 915-921.
-
(2006)
J Cell Biol
, vol.174
, pp. 915-921
-
-
Csordás, G.1
Renken, C.2
Várnai, P.3
Walter, L.4
Weaver, D.5
Buttle, K.F.6
-
22
-
-
0023008846
-
Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes
-
Misumi Y, Misumi Y, Miki K, Takatsuki A, Tamura G, Ikehara Y. Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. J Biol Chem 1986; 261: 11398-11403.
-
(1986)
J Biol Chem
, vol.261
, pp. 11398-11403
-
-
Misumi, Y.1
Misumi, Y.2
Miki, K.3
Takatsuki, A.4
Tamura, G.5
Ikehara, Y.6
-
23
-
-
80054051101
-
The regulation and physiology of mitochondrial proton leak
-
Divakaruni AS, Brand MD. The regulation and physiology of mitochondrial proton leak. Physiology 2011; 26: 192-205.
-
(2011)
Physiology
, vol.26
, pp. 192-205
-
-
Divakaruni, A.S.1
Brand, M.D.2
-
24
-
-
79955544880
-
Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation
-
Chambers JW, LoGrasso PV. Mitochondrial c-Jun N-terminal kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation. J Biol Chem 2011; 286: 16052-16062.
-
(2011)
J Biol Chem
, vol.286
, pp. 16052-16062
-
-
Chambers, J.W.1
Lograsso, P.V.2
-
25
-
-
80051999961
-
Selective inhibition of mitochondrial JNK signaling achieved using peptide mimicry of the Sab kinase interacting motif-1 (KIM1)
-
Chambers JW, Cherry L, Laughlin JD, Figuera-Losada M, Lograsso PV. Selective inhibition of mitochondrial JNK signaling achieved using peptide mimicry of the Sab kinase interacting motif-1 (KIM1). ACS Chem Biol 2011; 6: 808-818.
-
(2011)
ACS Chem Biol
, vol.6
, pp. 808-818
-
-
Chambers, J.W.1
Cherry, L.2
Laughlin, J.D.3
Figuera-Losada, M.4
Lograsso, P.V.5
-
26
-
-
10644248287
-
Sab (SH3BP5), a novel mitochondria-localized JNK-interacting protein
-
Wiltshire C, Gillespie DA, May GH. Sab (SH3BP5), a novel mitochondria-localized JNK-interacting protein. Biochem Soc Trans 2004; 32: 1075-1077.
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 1075-1077
-
-
Wiltshire, C.1
Gillespie, D.A.2
May, G.H.3
-
27
-
-
77955824765
-
An intimate liaison: Spatial organization of the endoplasmic reticulum-mitochondria relationship
-
de Brito OM, Scorrano L. An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship. EMBO J 2010; 29: 2715-2723.
-
(2010)
EMBO J
, vol.29
, pp. 2715-2723
-
-
De Brito, O.M.1
Scorrano, L.2
-
28
-
-
84859232387
-
Ero1a regulates Ca(2+) fluxes at the endoplasmic reticulum-mitochondria interface (MAM)
-
Anelli T, Bergamelli L, Margittai E, Rimessi A, Fagioli C, Malgaroli A et al. Ero1a regulates Ca(2+) fluxes at the endoplasmic reticulum-mitochondria interface (MAM). Antioxid Redox Signal 2012; 16: 1077-1087.
-
(2012)
Antioxid Redox Signal
, vol.16
, pp. 1077-1087
-
-
Anelli, T.1
Bergamelli, L.2
Margittai, E.3
Rimessi, A.4
Fagioli, C.5
Malgaroli, A.6
-
29
-
-
84881345531
-
Mitochondrial dysfunction indirectly elevates ROS production by the endoplasmic reticulum
-
Murphy MP. Mitochondrial dysfunction indirectly elevates ROS production by the endoplasmic reticulum. Cell Metab 2013; 18: 145-146.
-
(2013)
Cell Metab
, vol.18
, pp. 145-146
-
-
Murphy, M.P.1
-
30
-
-
4544235673
-
Calcium, ATP, and ROS: A mitochondrial love-hate triangle
-
Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS. Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am J Physiol Cell Physiol 2004; 287: 817-833.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
, pp. 817-833
-
-
Brookes, P.S.1
Yoon, Y.2
Robotham, J.L.3
Anders, M.W.4
Sheu, S.S.5
-
31
-
-
35848957485
-
Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword?
-
Malhotra JD, Kaufman RJ. Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid Redox Signal 2007; 9: 2277-2293.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2277-2293
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
32
-
-
47349099011
-
2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content
-
2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content. Cell Calcium 2008; 44: 324-338.
-
(2008)
Cell Calcium
, vol.44
, pp. 324-338
-
-
Hanson, C.J.1
Bootman, M.D.2
Distelhorst, C.W.3
Wojcikiewicz, R.J.4
Roderick, H.L.5
-
33
-
-
44749089373
-
High-and low-calcium-dependent mechanisms of mitochondrial calcium signalling
-
Spät A, Szanda G, Csordás G, Hajnóczky G. High-and low-calcium-dependent mechanisms of mitochondrial calcium signalling. Cell Calcium 2008; 44: 51-63.
-
(2008)
Cell Calcium
, vol.44
, pp. 51-63
-
-
Spät, A.1
Szanda, G.2
Csordás, G.3
Hajnóczky, G.4
-
34
-
-
84876063014
-
Regulation of drug-induced liver injury by signal transduction pathways: Critical role of mitochondria
-
Han D, Dara L, Win S, Than TA, Yuan L, Abbasi SQ et al. Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria. Trends Pharmacol Sci 2013; 34: 243-253.
-
(2013)
Trends Pharmacol Sci
, vol.34
, pp. 243-253
-
-
Han, D.1
Dara, L.2
Win, S.3
Than, T.A.4
Yuan, L.5
Abbasi, S.Q.6
-
36
-
-
4143087106
-
BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
-
Chae HJ, Kim HR, Xu C, Bailly-Maitre B, Krajewska M, Krajewski S et al. BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress. Mol Cell 2004; 15: 355-366.
-
(2004)
Mol Cell
, vol.15
, pp. 355-366
-
-
Chae, H.J.1
Kim, H.R.2
Xu, C.3
Bailly-Maitre, B.4
Krajewska, M.5
Krajewski, S.6
-
37
-
-
11844284861
-
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
-
Oakes SA, Scorrano L, Opferman JT, Bassik MC, Nishino M, Pozzan T et al. Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum. Proc Natl Acad Sci USA 2005; 102: 105-110.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 105-110
-
-
Oakes, S.A.1
Scorrano, L.2
Opferman, J.T.3
Bassik, M.C.4
Nishino, M.5
Pozzan, T.6
-
38
-
-
46449116985
-
Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition
-
Hansson MJ, Månsson R, Morota S, Uchino H, Kallur T, Sumi T et al. Calcium-induced generation of reactive oxygen species in brain mitochondria is mediated by permeability transition. Free Radic Biol Med 2008; 45: 284-294.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 284-294
-
-
Hansson, M.J.1
Månsson, R.2
Morota, S.3
Uchino, H.4
Kallur, T.5
Sumi, T.6
-
40
-
-
34248641140
-
Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2
-
Murakami Y, Aizu-Yokota E, Sonoda Y, Ohta S, Kasahara T. Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2. J Biochem 2007; 141: 401-410.
-
(2007)
J Biochem
, vol.141
, pp. 401-410
-
-
Murakami, Y.1
Aizu-Yokota, E.2
Sonoda, Y.3
Ohta, S.4
Kasahara, T.5
-
41
-
-
84855838914
-
Regulation of brefeldin A-induced ER stress and apoptosis by mitochondrial NADP-dependent isocitrate dehydrogenase
-
Moon JL, Kim SY, Shin SW, Park JW. Regulation of brefeldin A-induced ER stress and apoptosis by mitochondrial NADP-dependent isocitrate dehydrogenase. Biochem Biophys Res Commun 2012; 417: 760-764.
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 760-764
-
-
Moon, J.L.1
Kim, S.Y.2
Shin, S.W.3
Park, J.W.4
-
42
-
-
79959360187
-
Role of cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) in the initiation of mitochondrial biogenesis and stress response in liver cells
-
Than TA, Lou H, Ji C, Win S, Kaplowitz N. Role of cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) in the initiation of mitochondrial biogenesis and stress response in liver cells. J Biol Chem 2011; 286: 22047-22054.
-
(2011)
J Biol Chem
, vol.286
, pp. 22047-22054
-
-
Than, T.A.1
Lou, H.2
Ji, C.3
Win, S.4
Kaplowitz, N.5
|