Mitochondrial c-Jun N-terminal Kinase (JNK) signaling initiates physiological changes resulting in amplification of reactive oxygen species generation

Journal of Biological Chemistry

Volumn 286, Issue 18, 2011, Pages 16052-16062

  Chambers, Jeremy W ^a   LoGrasso, Philip V ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOMYCIN; C-JUN N-TERMINAL KINASE; CELL SURVIVAL; CELLULAR RESPONSE; CELLULAR STRESS; HELA CELL; INDUCED STRESS; MITOCHONDRIAL SUPEROXIDE; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; SEQUENCE OF EVENTS; SIGNALING CASCADES; SIGNIFICANT IMPACTS;

CELL CULTURE; DERIVATIVES; GENE EXPRESSION; OXYGEN; PHYSIOLOGY; SIGNAL TRANSDUCTION; SIGNALING;

MITOCHONDRIA;

ANISOMYCIN; PROTEIN SAB; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL FUNCTION; CELL ISOLATION; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; ENZYME INHIBITION; ENZYME SYNTHESIS; GENE AMPLIFICATION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALS; ANISOMYCIN; ELECTRON TRANSPORT COMPLEX I; FIBROBLASTS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; NADPH OXIDASE; PROTEIN SYNTHESIS INHIBITORS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 79955544880     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.223602     Document Type: Article

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