-
1
-
-
84884588696
-
Newborn bloodspot screening for Duchenne muscular dystrophy: 21 years experience in Wales (UK)
-
S. J. Moat, D. M. Bradley, R. Salmon, A. Clarke, L. Hartley, Newborn bloodspot screening for Duchenne muscular dystrophy: 21 years experience in Wales (UK). Eur. J. Hum. Genet. 21, 1049-1053 (2013).
-
(2013)
Eur. J. Hum. Genet.
, vol.21
, pp. 1049-1053
-
-
Moat, S.J.1
Bradley, D.M.2
Salmon, R.3
Clarke, A.4
Hartley, L.5
-
2
-
-
84859181514
-
Evidence-based path to newborn screening for Duchenne muscular dystrophy
-
J. R. Mendell, C. Shilling, N. D. Leslie, K. M. Flanigan, R. Al-Dahhak, J. Gastier-Foster, K. Kneile, D. M. Dunn, B. Duval, A. Aoyagi, C. Hamil, M. Mahmoud, K. Roush, L. Bird, C. Rankin, H. Lilly, N. Street, R. Chandrasekar, R. B. Weiss, Evidence-based path to newborn screening for Duchenne muscular dystrophy. Ann. Neurol. 71, 304-313 (2012).
-
(2012)
Ann. Neurol.
, vol.71
, pp. 304-313
-
-
Mendell, J.R.1
Shilling, C.2
Leslie, N.D.3
Flanigan, K.M.4
Al-Dahhak, R.5
Gastier-Foster, J.6
Kneile, K.7
Dunn, D.M.8
Duval, B.9
Aoyagi, A.10
Hamil, C.11
Mahmoud, M.12
Roush, K.13
Bird, L.14
Rankin, C.15
Lilly, H.16
Street, N.17
Chandrasekar, R.18
Weiss, R.B.19
-
3
-
-
84878016335
-
Therapy for Duchenne muscular dystrophy: Renewed optimism from genetic approaches
-
R. J. Fairclough, M. J. Wood, K. E. Davies, Therapy for Duchenne muscular dystrophy: Renewed optimism from genetic approaches. Nat. Rev. Genet. 14, 373-378 (2013).
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 373-378
-
-
Fairclough, R.J.1
Wood, M.J.2
Davies, K.E.3
-
4
-
-
84905483293
-
Muscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of Duchenne muscular dystrophy
-
A. Chalkiadaki, M. Igarashi, A. S. Nasamu, J. Knezevic, L. Guarente, Muscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of Duchenne muscular dystrophy. PLOS Genet. 10, e1004490 (2014).
-
(2014)
PLOS Genet.
, vol.10
, pp. e1004490
-
-
Chalkiadaki, A.1
Igarashi, M.2
Nasamu, A.S.3
Knezevic, J.4
Guarente, L.5
-
5
-
-
34147109662
-
PGC-1a regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy
-
C. Handschin, Y. M. Kobayashi, S. Chin, P. Seale, K. P. Campbell, B. M. Spiegelman, PGC-1a regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy. Genes Dev. 21, 770-783 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 770-783
-
-
Handschin, C.1
Kobayashi, Y.M.2
Chin, S.3
Seale, P.4
Campbell, K.P.5
Spiegelman, B.M.6
-
6
-
-
33750825245
-
PGC-1a protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
-
M. Sandri, J. Lin, C. Handschin, W. Yang, Z. P. Arany, S. H. Lecker, A. L. Goldberg, B. M. Spiegelman, PGC-1a protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc. Natl. Acad. Sci. U. S. A. 103, 16260-16265 (2006).
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 16260-16265
-
-
Sandri, M.1
Lin, J.2
Handschin, C.3
Yang, W.4
Arany, Z.P.5
Lecker, S.H.6
Goldberg, A.L.7
Spiegelman, B.M.8
-
7
-
-
84886899121
-
SIRT1 protein, by blocking the activities of transcription factors FoxO1 and FoxO3, inhibits muscle atrophy and promotes muscle growth
-
D. Lee, A. L. Goldberg, SIRT1 protein, by blocking the activities of transcription factors FoxO1 and FoxO3, inhibits muscle atrophy and promotes muscle growth. J. Biol. Chem. 288, 30515-30526 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 30515-30526
-
-
Lee, D.1
Goldberg, A.L.2
-
8
-
-
84872094183
-
Cellular and molecular mechanisms of muscle atrophy
-
P. Bonaldo, M. Sandri, Cellular and molecular mechanisms of muscle atrophy. Dis. Models & Mech. 6, 25-39 (2013).
-
(2013)
Dis. Models & Mech.
, vol.6
, pp. 25-39
-
-
Bonaldo, P.1
Sandri, M.2
-
9
-
-
84862022077
-
The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
-
C. Cantó, R. H. Houtkooper, E. Pirinen, D. Y. Youn, M. H. Oosterveer, Y. Cen, P. J. Fernandez-Marcos, H. Yamamoto, P. A. Andreux, P. Cettour-Rose, K. Gademann, C. Rinsch, K. Schoonjans, A. A. Sauve, J. Auwerx, The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metab. 15, 838-847 (2012).
-
(2012)
Cell Metab.
, vol.15
, pp. 838-847
-
-
Cantó, C.1
Houtkooper, R.H.2
Pirinen, E.3
Youn, D.Y.4
Oosterveer, M.H.5
Cen, Y.6
Fernandez-Marcos, P.J.7
Yamamoto, H.8
Andreux, P.A.9
Cettour-Rose, P.10
Gademann, K.11
Rinsch, C.12
Schoonjans, K.13
Sauve, A.A.14
Auwerx, J.15
-
10
-
-
84880517634
-
The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling
-
L. Mouchiroud, R. H. Houtkooper, N. Moullan, E. Katsyuba, D. Ryu, C. Cantó, A. Mottis, Y.-S. Jo, M. Viswanathan, K. Schoonjans, L. Guarente, J. Auwerx, The NAD+/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling. Cell 154, 430-441 (2013).
-
(2013)
Cell
, vol.154
, pp. 430-441
-
-
Mouchiroud, L.1
Houtkooper, R.H.2
Moullan, N.3
Katsyuba, E.4
Ryu, D.5
Cantó, C.6
Mottis, A.7
Jo, Y.-S.8
Viswanathan, M.9
Schoonjans, K.10
Guarente, L.11
Auwerx, J.12
-
11
-
-
84902270555
-
Pharmacological Inhibition of poly (ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle
-
E. Pirinen, C. Cantó, Y. S. Jo, L. Morato, H. Zhang, K. J. Menzies, E. G. Williams, L. Mouchiroud, N. Moullan, C. Hagberg, W. Li, S. Timmers, R. Imhof, J. Verbeek, A. Pujol, B. Van Loon, C. Viscomi, M. Zeviani, P. Schrauwen, A. A. Sauve, K. Schoonjans, J. Auwerx, Pharmacological Inhibition of poly (ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle. Cell Metab. 19, 1034-1041 (2014).
-
(2014)
Cell Metab.
, vol.19
, pp. 1034-1041
-
-
Pirinen, E.1
Cantó, C.2
Jo, Y.S.3
Morato, L.4
Zhang, H.5
Menzies, K.J.6
Williams, E.G.7
Mouchiroud, L.8
Moullan, N.9
Hagberg, C.10
Li, W.11
Timmers, S.12
Imhof, R.13
Verbeek, J.14
Pujol, A.15
Van Loon, B.16
Viscomi, C.17
Zeviani, M.18
Schrauwen, P.19
Sauve, A.A.20
Schoonjans, K.21
Auwerx, J.22
more..
-
12
-
-
80053920774
-
Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice
-
J. Yoshino, K. F. Mills, M. J. Yoon, S.-i. Imai, Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 14, 528-536 (2011).
-
(2011)
Cell Metab.
, vol.14
, pp. 528-536
-
-
Yoshino, J.1
Mills, K.F.2
Yoon, M.J.3
Imai, S.-I.4
-
13
-
-
84893442805
-
Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
-
A. P. Gomes, N. L. Price, A. J. Y. Ling, J. J. Moslehi, M. K. Montgomery, L. Rajman, J. P. White, J. S. Teodoro, C. D. Wrann, B. P. Hubbard, E. M. Mercken, C. M. Palmeira, R. De Cabo, A. P. Rolo, N. Turner, E. L. Bell, D. A. Sinclair, Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell 155, 1624-1638 (2013).
-
(2013)
Cell
, vol.155
, pp. 1624-1638
-
-
Gomes, A.P.1
Price, N.L.2
Ling, A.J.Y.3
Moslehi, J.J.4
Montgomery, M.K.5
Rajman, L.6
White, J.P.7
Teodoro, J.S.8
Wrann, C.D.9
Hubbard, B.P.10
Mercken, E.M.11
Palmeira, C.M.12
De Cabo, R.13
Rolo, A.P.14
Turner, N.15
Bell, E.L.16
Sinclair, D.A.17
-
14
-
-
84950327004
-
Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice
-
K. Gariani, K. J. Menzies, D. Ryu, C. J. Wegner, X. Wang, E. R. Ropelle, N. Moullan, H. Zhang, A. Perino, V. Lemos, B. Kim, Y.-K. Park, A. Piersigilli, T. X. Pham, Y. Yang, C. S. Ku, S. I. Koo, A. Fomitchova, C. Cantó, K. Schoonjans, A. A. Sauve, J. Y. Lee, J. Auwerx, Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice. Hepatology 63, 1190-1204 (2016).
-
(2016)
Hepatology
, vol.63
, pp. 1190-1204
-
-
Gariani, K.1
Menzies, K.J.2
Ryu, D.3
Wegner, C.J.4
Wang, X.5
Ropelle, E.R.6
Moullan, N.7
Zhang, H.8
Perino, A.9
Lemos, V.10
Kim, B.11
Park, Y.-K.12
Piersigilli, A.13
Pham, T.X.14
Yang, Y.15
Ku, C.S.16
Koo, S.I.17
Fomitchova, A.18
Cantó, C.19
Schoonjans, K.20
Sauve, A.A.21
Lee, J.Y.22
Auwerx, J.23
more..
-
15
-
-
79953752384
-
PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation
-
P. Bai, C. Cantó, H. Oudart, A. Brunyánszki, Y. Cen, C. Thomas, H. Yamamoto, A. Huber, B. Kiss, R. H. Houtkooper, K. Schoonjans, V. Schreiber, A. A. Sauve, J. Menissier-De Murcia, J. Auwerx, PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation. Cell Metab. 13, 461-468 (2011).
-
(2011)
Cell Metab.
, vol.13
, pp. 461-468
-
-
Bai, P.1
Cantó, C.2
Oudart, H.3
Brunyánszki, A.4
Cen, Y.5
Thomas, C.6
Yamamoto, H.7
Huber, A.8
Kiss, B.9
Houtkooper, R.H.10
Schoonjans, K.11
Schreiber, V.12
Sauve, A.A.13
Menissier-De Murcia, J.14
Auwerx, J.15
-
16
-
-
80053640237
-
Telomere shortening is associated to TRF1 and PARP1 overexpression in Duchenne muscular dystrophy
-
M. H. Aguennouz, G. L. Vita, S. Messina, A. Cama, N. Lanzano, A. Ciranni, C. Rodolico, R. M. Di Giorgio, G. Vita, Telomere shortening is associated to TRF1 and PARP1 overexpression in Duchenne muscular dystrophy. Neurobiol. Aging 32, 2190-2197 (2011).
-
(2011)
Neurobiol. Aging
, vol.32
, pp. 2190-2197
-
-
Aguennouz, M.H.1
Vita, G.L.2
Messina, S.3
Cama, A.4
Lanzano, N.5
Ciranni, A.6
Rodolico, C.7
Di Giorgio, R.M.8
Vita, G.9
-
17
-
-
84965034275
-
NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
-
H. Zhang, D. Ryu, Y. Wu, K. Gariani, X. Wang, P. Luan, D. D'Amico, E. R. Ropelle, M. P. Lutolf, R. Aebersold, K. Schoonjans, K. J. Menzies, J. Auwerx, NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice. Science 352, 1436-1443 (2016).
-
(2016)
Science
, vol.352
, pp. 1436-1443
-
-
Zhang, H.1
Ryu, D.2
Wu, Y.3
Gariani, K.4
Wang, X.5
Luan, P.6
D'Amico, D.7
Ropelle, E.R.8
Lutolf, M.P.9
Aebersold, R.10
Schoonjans, K.11
Menzies, K.J.12
Auwerx, J.13
-
18
-
-
84868108276
-
NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy
-
M. F. Goody, M. W. Kelly, C. J. Reynolds, A. Khalil, B. D. Crawford, C. A. Henry, NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy. PLOS Biol. 10, e1001409 (2012).
-
(2012)
PLOS Biol.
, vol.10
, pp. e1001409
-
-
Goody, M.F.1
Kelly, M.W.2
Reynolds, C.J.3
Khalil, A.4
Crawford, B.D.5
Henry, C.A.6
-
19
-
-
84937522438
-
NAD+ metabolism and the control of energy homeostasis: A balancing act between mitochondria and the nucleus
-
C. Cantó, K. J. Menzies, J. Auwerx, NAD+ metabolism and the control of energy homeostasis: A balancing act between mitochondria and the nucleus. Cell Metab. 22, 31-53 (2015).
-
(2015)
Cell Metab.
, vol.22
, pp. 31-53
-
-
Cantó, C.1
Menzies, K.J.2
Auwerx, J.3
-
20
-
-
84866420982
-
Systems genetics of metabolism: The use of the BXD murine reference panel for multiscalar integration of traits
-
P. A. Andreux, E. G. Williams, H. Koutnikova, R. H. Houtkooper, M.-F. Champy, H. Henry, K. Schoonjans, R. W. Williams, J. Auwerx, Systems genetics of metabolism: The use of the BXD murine reference panel for multiscalar integration of traits. Cell 150, 1287-1299 (2012).
-
(2012)
Cell
, vol.150
, pp. 1287-1299
-
-
Andreux, P.A.1
Williams, E.G.2
Koutnikova, H.3
Houtkooper, R.H.4
Champy, M.-F.5
Henry, H.6
Schoonjans, K.7
Williams, R.W.8
Auwerx, J.9
-
21
-
-
84975156981
-
Systems proteomics of liver mitochondria function
-
E. G. Williams, Y. Wu, P. Jha, S. Dubuis, P. Blattmann, C. A. Argmann, S. M. Houten, T. Amariuta, W. Wolski, N. Zamboni, R. Aebersold, J. Auwerx, Systems proteomics of liver mitochondria function. Science 352, aad0189 (2016).
-
(2016)
Science
, vol.352
, pp. aad0189
-
-
Williams, E.G.1
Wu, Y.2
Jha, P.3
Dubuis, S.4
Blattmann, P.5
Argmann, C.A.6
Houten, S.M.7
Amariuta, T.8
Wolski, W.9
Zamboni, N.10
Aebersold, R.11
Auwerx, J.12
-
22
-
-
84908077262
-
Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population
-
Y. Wu, E. G. Williams, S. Dubuis, A. Mottis, V. Jovaisaite, S. M. Houten, C. A. Argmann, P. Faridi, W. Wolski, Z. Kutalik, N. Zamboni, J. Auwerx, R. Aebersold, Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population. Cell 158, 1415-1430 (2014).
-
(2014)
Cell
, vol.158
, pp. 1415-1430
-
-
Wu, Y.1
Williams, E.G.2
Dubuis, S.3
Mottis, A.4
Jovaisaite, V.5
Houten, S.M.6
Argmann, C.A.7
Faridi, P.8
Wolski, W.9
Kutalik, Z.10
Zamboni, N.11
Auwerx, J.12
Aebersold, R.13
-
23
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
A. Subramanian, P. Tamayo, V. K. Mootha, S. Mukherjee, B. L. Ebert, M. A. Gillette, A. Paulovich, S. L. Pomeroy, T. R. Golub, E. S. Lander, J. P. Mesirov, Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl. Acad. Sci. U. S. A. 102, 15545-15550 (2005).
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
24
-
-
32644441628
-
Nuclear envelope dystrophies show a transcriptional fingerprint suggesting disruption of Rb-MyoD pathways in muscle regeneration
-
M. Bakay, Z. Wang, G. Melcon, L. Schiltz, J. Xuan, P. Zhao, V. Sartorelli, J. Seo, E. Pegoraro, C. Angelini, B. Shneiderman, D. Escolar, Y.-W. Chen, S. T. Winokur, L. M. Pachman, C. Fan, R. Mandler, Y. Nevo, E. Gordon, Y. Zhu, Y. Dong, Y. Wang, E. P. Hoffman, Nuclear envelope dystrophies show a transcriptional fingerprint suggesting disruption of Rb-MyoD pathways in muscle regeneration. Brain 129, 996-1013 (2006).
-
(2006)
Brain
, vol.129
, pp. 996-1013
-
-
Bakay, M.1
Wang, Z.2
Melcon, G.3
Schiltz, L.4
Xuan, J.5
Zhao, P.6
Sartorelli, V.7
Seo, J.8
Pegoraro, E.9
Angelini, C.10
Shneiderman, B.11
Escolar, D.12
Chen, Y.-W.13
Winokur, S.T.14
Pachman, L.M.15
Fan, C.16
Mandler, R.17
Nevo, Y.18
Gordon, E.19
Zhu, Y.20
Dong, Y.21
Wang, Y.22
Hoffman, E.P.23
more..
-
25
-
-
84908367208
-
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy
-
S. Dadgar, Z. Wang, H. Johnston, A. Kesari, K. Nagaraju, Y.-W. Chen, D. A. Hill, T. A. Partridge, M. Giri, R. J. Freishtat, J. Nazarian, J. Xuan, Y. Wang, E. P. Hoffman, Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy. J. Cell Biol. 207, 139-158 (2014).
-
(2014)
J. Cell Biol.
, vol.207
, pp. 139-158
-
-
Dadgar, S.1
Wang, Z.2
Johnston, H.3
Kesari, A.4
Nagaraju, K.5
Chen, Y.-W.6
Hill, D.A.7
Partridge, T.A.8
Giri, M.9
Freishtat, R.J.10
Nazarian, J.11
Xuan, J.12
Wang, Y.13
Hoffman, E.P.14
-
26
-
-
84900410413
-
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
-
D. Kraus, Q. Yang, D. Kong, A. S. Banks, L. Zhang, J. T. Rodgers, E. Pirinen, T. C. Pulinilkunnil, F. Gong, Y.-c. Wang, Y. Cen, A. A. Sauve, J. M. Asara, O. D. Peroni, B. P. Monia, S. Bhanot, L. Alhonen, P. Puigserver, B. B. Kahn, Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature 508, 258-262 (2014).
-
(2014)
Nature
, vol.508
, pp. 258-262
-
-
Kraus, D.1
Yang, Q.2
Kong, D.3
Banks, A.S.4
Zhang, L.5
Rodgers, J.T.6
Pirinen, E.7
Pulinilkunnil, T.C.8
Gong, F.9
Wang, Y.-I.10
Cen, Y.11
Sauve, A.A.12
Asara, J.M.13
Peroni, O.D.14
Monia, B.P.15
Bhanot, S.16
Alhonen, L.17
Puigserver, P.18
Kahn, B.B.19
-
27
-
-
0028225401
-
Human liver nicotinamide N-methyltransferase. CDNA cloning, expression, and biochemical characterization
-
S. Aksoy, C. L. Szumlanski, R. M. Weinshilboum, Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization. J. Biol. Chem. 269, 14835-14840 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 14835-14840
-
-
Aksoy, S.1
Szumlanski, C.L.2
Weinshilboum, R.M.3
-
28
-
-
77953631698
-
The secret life of NAD+: An old metabolite controlling new metabolic signaling pathways
-
R. H. Houtkooper, C. Cantó, R. J. Wanders, J. Auwerx, The secret life of NAD+: An old metabolite controlling new metabolic signaling pathways. Endocr. Rev. 31, 194-223 (2010).
-
(2010)
Endocr. Rev.
, vol.31
, pp. 194-223
-
-
Houtkooper, R.H.1
Cantó, C.2
Wanders, R.J.3
Auwerx, J.4
-
29
-
-
84864773923
-
Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy
-
J. M. Percival, N. P. Whitehead, M. E. Adams, C. M. Adamo, J. A. Beavo, S. C. Froehner, Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy. J. Pathol. 228, 77-87 (2012).
-
(2012)
J. Pathol.
, vol.228
, pp. 77-87
-
-
Percival, J.M.1
Whitehead, N.P.2
Adams, M.E.3
Adamo, C.M.4
Beavo, J.A.5
Froehner, S.C.6
-
30
-
-
34247502715
-
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
-
P. Belenky, F. G. Racette, K. L. Bogan, J. M. McClure, J. S. Smith, C. Brenner, Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. Cell 129, 473-484 (2007).
-
(2007)
Cell
, vol.129
, pp. 473-484
-
-
Belenky, P.1
Racette, F.G.2
Bogan, K.L.3
McClure, J.M.4
Smith, J.S.5
Brenner, C.6
-
31
-
-
0034699346
-
Genetic suppression of phenotypes arising from mutations in dystrophin-related genes in Caenorhabditis elegans
-
K. Gieseler, K. Grisoni, L. Ségalat, Genetic suppression of phenotypes arising from mutations in dystrophin-related genes in Caenorhabditis elegans. Curr. Biol. 10, 1092-1097 (2000).
-
(2000)
Curr. Biol.
, vol.10
, pp. 1092-1097
-
-
Gieseler, K.1
Grisoni, K.2
Ségalat, L.3
-
32
-
-
84886476382
-
Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
-
K. Schmeisser, J. Mansfeld, D. Kuhlow, S. Weimer, S. Priebe, I. Heiland, M. Birringer, M. Groth, A. Segref, Y. Kanfi, N. L. Price, S. Schmeisser, S. Schuster, A. F. H. Pfeiffer, R. Guthke, M. Platzer, T. Hoppe, H. Y. Cohen, K. Zarse, D. A. Sinclair, M. Ristow, Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide. Nat. Chem. Biol. 9, 693-700 (2013).
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 693-700
-
-
Schmeisser, K.1
Mansfeld, J.2
Kuhlow, D.3
Weimer, S.4
Priebe, S.5
Heiland, I.6
Birringer, M.7
Groth, M.8
Segref, A.9
Kanfi, Y.10
Price, N.L.11
Schmeisser, S.12
Schuster, S.13
Pfeiffer, A.F.H.14
Guthke, R.15
Platzer, M.16
Hoppe, T.17
Cohen, H.Y.18
Zarse, K.19
Sinclair, D.A.20
Ristow, M.21
more..
-
33
-
-
4344658776
-
Evolution of the mdx mouse cardiomyopathy: Physiological and morphological findings
-
J. G. Quinlan, H. S. Hahn, B. L. Wong, J. N. Lorenz, A. S. Wenisch, L. S. Levin, Evolution of the mdx mouse cardiomyopathy: Physiological and morphological findings. Neuromuscul. Disord. 14, 491-496 (2004).
-
(2004)
Neuromuscul. Disord.
, vol.14
, pp. 491-496
-
-
Quinlan, J.G.1
Hahn, H.S.2
Wong, B.L.3
Lorenz, J.N.4
Wenisch, A.S.5
Levin, L.S.6
-
34
-
-
3242719545
-
Modulation of NF-kB-dependent transcription and cell survival by the SIRT1 deacetylase
-
F. Yeung, J. E. Hoberg, C. S. Ramsey, M. D. Keller, D. R. Jones, R. A. Frye, M. W. Mayo, Modulation of NF-kB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23, 2369-2380 (2004).
-
(2004)
EMBO J.
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
35
-
-
75949096894
-
Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
-
A. W. B. Joe, L. Yi, A. Natarajan, F. Le Grand, L. So, J. Wang, M. A. Rudnicki, F. M. Rossi, Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis. Nat. Cell Biol. 12, 153-163 (2010).
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 153-163
-
-
Joe, A.W.B.1
Yi, L.2
Natarajan, A.3
Le Grand, F.4
So, L.5
Wang, J.6
Rudnicki, M.A.7
Rossi, F.M.8
-
36
-
-
84876274371
-
Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration
-
J. E. Heredia, L. Mukundan, F. M. Chen, A. A. Mueller, R. C. Deo, R. M. Locksley, T. A. Rando, A. Chawla, Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. Cell 153, 376-388 (2013).
-
(2013)
Cell
, vol.153
, pp. 376-388
-
-
Heredia, J.E.1
Mukundan, L.2
Chen, F.M.3
Mueller, A.A.4
Deo, R.C.5
Locksley, R.M.6
Rando, T.A.7
Chawla, A.8
-
37
-
-
84938096484
-
Fat deposition and accumulation in the damaged and inflamed skeletal muscle: Cellular and molecular players
-
C. Sciorati, E. Clementi, A. A. Manfredi, P. Rovere-Querini, Fat deposition and accumulation in the damaged and inflamed skeletal muscle: Cellular and molecular players. Cell. Mol. Life Sci. 72, 2135-2156 (2015).
-
(2015)
Cell. Mol. Life Sci.
, vol.72
, pp. 2135-2156
-
-
Sciorati, C.1
Clementi, E.2
Manfredi, A.A.3
Rovere-Querini, P.4
-
38
-
-
84896361698
-
Nitric oxide controls fat deposition in dystrophic skeletal muscle by regulating fibro-adipogenic precursor differentiation
-
N. Cordani, V. Pisa, L. Pozzi, C. Sciorati, E. Clementi, Nitric oxide controls fat deposition in dystrophic skeletal muscle by regulating fibro-adipogenic precursor differentiation. Stem Cells 32, 874-885 (2014).
-
(2014)
Stem Cells
, vol.32
, pp. 874-885
-
-
Cordani, N.1
Pisa, V.2
Pozzi, L.3
Sciorati, C.4
Clementi, E.5
-
39
-
-
84899494248
-
Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis
-
P. Mukhopadhyay, M. Rajesh, Z. Cao, B. Horváth, O. Park, H. Wang, K. Erdelyi, E. Holovac, Y. Wang, L. Liaudet, N. Hamdaoui, F. Lafdil, G. Haskó, C. Szabo, A. H. Boulares, B. Gao, P. Pacher, Poly (ADP-ribose) polymerase-1 is a key mediator of liver inflammation and fibrosis. Hepatology 59, 1998-2009 (2014).
-
(2014)
Hepatology
, vol.59
, pp. 1998-2009
-
-
Mukhopadhyay, P.1
Rajesh, M.2
Cao, Z.3
Horváth, B.4
Park, O.5
Wang, H.6
Erdelyi, K.7
Holovac, E.8
Wang, Y.9
Liaudet, L.10
Hamdaoui, N.11
Lafdil, F.12
Haskó, G.13
Szabo, C.14
Boulares, A.H.15
Gao, B.16
Pacher, P.17
-
40
-
-
84962030356
-
Evidence for a direct effect of the NAD+ precursor Acipimox on muscle mitochondrial function in humans
-
T. Van De Weijer, E. Phielix, L. Bilet, E. G. Williams, E. R. Ropelle, A. Bierwagen, R. Livingstone, P. Nowotny, L. M. Sparks, S. Paglialunga, J. Szendroedi, B. Havekes, N. Moullan, E. Pirinen, J.-H. Hwang, V. B. Schrauwen-Hinderling, M. K. C. Hesselink, J. Auwerx, M. Roden, P. Schrauwen, Evidence for a direct effect of the NAD+ precursor Acipimox on muscle mitochondrial function in humans. Diabetes 64, 1193-1201 (2014).
-
(2014)
Diabetes
, vol.64
, pp. 1193-1201
-
-
Van De Weijer, T.1
Phielix, E.2
Bilet, L.3
Williams, E.G.4
Ropelle, E.R.5
Bierwagen, A.6
Livingstone, R.7
Nowotny, P.8
Sparks, L.M.9
Paglialunga, S.10
Szendroedi, J.11
Havekes, B.12
Moullan, N.13
Pirinen, E.14
Hwang, J.-H.15
Schrauwen-Hinderling, V.B.16
Hesselink, M.K.C.17
Auwerx, J.18
Roden, M.19
Schrauwen, P.20
more..
-
41
-
-
59649117804
-
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner
-
F. Van Gool, M. Gallí, C. Gueydan, V. Kruys, P.-P. Prevot, A. Bedalov, R. Mostoslavsky, F. W. Alt, T. De Smedt, O. Leo, Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner. Nat. Med. 15, 206-210 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 206-210
-
-
Van Gool, F.1
Gallí, M.2
Gueydan, C.3
Kruys, V.4
Prevot, P.-P.5
Bedalov, A.6
Mostoslavsky, R.7
Alt, F.W.8
De Smedt, T.9
Leo, O.10
-
42
-
-
78049414814
-
PARP inhibitors: New tools to protect from inflammation
-
V. Giansanti, F. Donà, M. Tillhon, A. I. Scovassi, PARP inhibitors: New tools to protect from inflammation. Biochem. Pharmacol. 80, 1869-1877 (2010).
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1869-1877
-
-
Giansanti, V.1
Donà, F.2
Tillhon, M.3
Scovassi, A.I.4
-
43
-
-
84948807305
-
Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects
-
J. Traba, M. Kwarteng-Siaw, T. C. Okoli, J. Li, R. D. Huffstutler, A. Bray, M. A. Waclawiw, K. Han, M. Pelletier, A. A. Sauve, R. M. Siegel, M. N. Sack, Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects. J. Clin. Invest. 125, 4592-4600 (2015).
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 4592-4600
-
-
Traba, J.1
Kwarteng-Siaw, M.2
Okoli, T.C.3
Li, J.4
Huffstutler, R.D.5
Bray, A.6
Waclawiw, M.A.7
Han, K.8
Pelletier, M.9
Sauve, A.A.10
Siegel, R.M.11
Sack, M.N.12
-
44
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
A. Brunet, L. B. Sweeney, J. F. Sturgill, K. F. Chua, P. L. Greer, Y. Lin, H. Tran, S. E. Ross, R. Mostoslavsky, H. Y. Cohen, L. S. Hu, H.-L. Cheng, M. P. Jedrychowski, S. P. Gygi, D. A. Sinclair, F. W. Alt, M. E. Greenberg, Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011-2015 (2004).
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.-L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
45
-
-
49249127869
-
Genetic background determines metabolic phenotypes in the mouse
-
M.-F. Champy, M. Selloum, V. Zeitler, C. Caradec, B. Jung, S. Rousseau, L. Pouilly, T. Sorg, J. Auwerx, Genetic background determines metabolic phenotypes in the mouse. Mamm. Genome 19, 318-331 (2008).
-
(2008)
Mamm. Genome
, vol.19
, pp. 318-331
-
-
Champy, M.-F.1
Selloum, M.2
Zeitler, V.3
Caradec, C.4
Jung, B.5
Rousseau, S.6
Pouilly, L.7
Sorg, T.8
Auwerx, J.9
-
46
-
-
81055125669
-
NCoR1 Is a conserved physiological modulator of muscle mass and oxidative function
-
H. Yamamoto, E. G. Williams, L. Mouchiroud, C. Cantó, W. Fan, M. Downes, C. Héligon, G. D. Barish, B. Desvergne, R. M. Evans, K. Schoonjans, J. Auwerx, NCoR1 Is a conserved physiological modulator of muscle mass and oxidative function. Cell 147, 827-839 (2011).
-
(2011)
Cell
, vol.147
, pp. 827-839
-
-
Yamamoto, H.1
Williams, E.G.2
Mouchiroud, L.3
Cantó, C.4
Fan, W.5
Downes, M.6
Héligon, C.7
Barish, G.D.8
Desvergne, B.9
Evans, R.M.10
Schoonjans, K.11
Auwerx, J.12
-
47
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1a
-
M. Lagouge, C. Argmann, Z. Gerhart-Hines, H. Meziane, C. Lerin, F. Daussin, N. Messadeq, J. Milne, P. Lambert, P. Elliott, B. Geny, M. Laakso, P. Puigserver, J. Auwerx, Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1a. Cell 127, 1109-1122 (2006).
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
48
-
-
33846946114
-
Angiotensin II type 1 receptor blockade attenuates TGF-b-induced failure of muscle regeneration in multiple myopathic states
-
R. D. Cohn, C. Van Erp, J. P. Habashi, A. A. Soleimani, E. C. Klein, M. T. Lisi, M. Gamradt, C. M. Ap Rhys, T. M. Holm, B. L. Loeys, F. Ramirez, D. P. Judge, C. W. Ward, H. C. Dietz, Angiotensin II type 1 receptor blockade attenuates TGF-b-induced failure of muscle regeneration in multiple myopathic states. Nat. Med. 13, 204-210 (2007).
-
(2007)
Nat. Med.
, vol.13
, pp. 204-210
-
-
Cohn, R.D.1
Van Erp, C.2
Habashi, J.P.3
Soleimani, A.A.4
Klein, E.C.5
Lisi, M.T.6
Gamradt, M.7
Ap Rhys, C.M.8
Holm, T.M.9
Loeys, B.L.10
Ramirez, F.11
Judge, D.P.12
Ward, C.W.13
Dietz, H.C.14
-
49
-
-
84910145057
-
A SIRT7-dependent acetylation switch of GABPb1 controls mitochondrial function
-
D. Ryu, Y. S. Jo, G. Lo Sasso, S. Stein, H. Zhang, A. Perino, J. U. Lee, M. Zeviani, R. Romand, M. O. Hottiger, K. Schoonjans, J. Auwerx, A SIRT7-dependent acetylation switch of GABPb1 controls mitochondrial function. Cell Metab. 20, 856-869 (2014).
-
(2014)
Cell Metab.
, vol.20
, pp. 856-869
-
-
Ryu, D.1
Jo, Y.S.2
Lo Sasso, G.3
Stein, S.4
Zhang, H.5
Perino, A.6
Lee, J.U.7
Zeviani, M.8
Romand, R.9
Hottiger, M.O.10
Schoonjans, K.11
Auwerx, J.12
-
50
-
-
84925152196
-
Tetracyclines disturb mitochondrial function across eukaryotic models: A call for caution in biomedical research
-
N. Moullan, L. Mouchiroud, X. Wang, D. Ryu, E. G. Williams, A. Mottis, V. Jovaisaite, M. V. Frochaux, P. M. Quiros, B. Deplancke, R. H. Houtkooper, J. Auwerx, Tetracyclines disturb mitochondrial function across eukaryotic models: A call for caution in biomedical research. Cell Rep. 10, 1681-1691 (2015).
-
(2015)
Cell Rep.
, vol.10
, pp. 1681-1691
-
-
Moullan, N.1
Mouchiroud, L.2
Wang, X.3
Ryu, D.4
Williams, E.G.5
Mottis, A.6
Jovaisaite, V.7
Frochaux, M.V.8
Quiros, P.M.9
Deplancke, B.10
Houtkooper, R.H.11
Auwerx, J.12
-
51
-
-
84866546747
-
Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle
-
M. P. Siegel, T. Wilbur, M. Mathis, E. G. Shankland, A. Trieu, M.-E. Harper, D. J. Marcinek, Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle. Mech. Ageing Dev. 133, 620-628 (2012).
-
(2012)
Mech. Ageing Dev.
, vol.133
, pp. 620-628
-
-
Siegel, M.P.1
Wilbur, T.2
Mathis, M.3
Shankland, E.G.4
Trieu, A.5
Harper, M.-E.6
Marcinek, D.J.7
-
52
-
-
84937961381
-
A stepwise procedure to test contractility and susceptibility to injury for the rodent quadriceps muscle
-
S. J. P. Pratt, R. M. Lovering, A stepwise procedure to test contractility and susceptibility to injury for the rodent quadriceps muscle. J. Biol. Methods 1, e8 (2014).
-
(2014)
J. Biol. Methods
, vol.1
, pp. e8
-
-
Pratt, S.J.P.1
Lovering, R.M.2
-
53
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
D. J. Klionsky, D. J. Klionsky, F. C. Abdalla, H. Abeliovich, R. T. Abraham, A. Acevedo-Arozena, K. Adeli, L. Agholme, M. Agnello, P. Agostinis, J. A. Aguirre-Ghiso, H. J. Ahn, O. Ait-Mohamed, S. Ait-Si-Ali, T. Akematsu, S., et al. Zuckerbraun, Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8, 445-544 (2012).
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Klionsky, D.J.2
Abdalla, F.C.3
Abeliovich, H.4
Abraham, R.T.5
Acevedo-Arozena, A.6
Adeli, K.7
Agholme, L.8
Agnello, M.9
Agostinis, P.10
Aguirre-Ghiso, J.A.11
Ahn, H.J.12
Ait-Mohamed, O.13
Ait-Si-Ali, S.14
Akematsu, T.15
Akira, S.16
-
54
-
-
0021724834
-
Dominant mutations affecting muscle structure in Caenorhabditis elegans that map near the actin gene cluster
-
R. H. Waterston, D. Hirsh, T. R. Lane, Dominant mutations affecting muscle structure in Caenorhabditis elegans that map near the actin gene cluster. J. Mol. Biol. 180, 473-496 (1984).
-
(1984)
J. Mol. Biol.
, vol.180
, pp. 473-496
-
-
Waterston, R.H.1
Hirsh, D.2
Lane, T.R.3
-
55
-
-
84978136448
-
Urolithin A induces mitophagy and prolongs lifespan in C. Elegans and increases muscle function in rodents
-
D. Ryu, L. Mouchiroud, P. A. Andreux, E. Katsyuba, N. Moullan, A. A. Nicolet-Dit-Felix, E. G. Williams, P. Jha, G. Lo Sasso, D. Huzard, P. Aebischer, C. Sandi, C. Rinsch, J. Auwerx, Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nat. Med. 22, 879-888 (2016).
-
(2016)
Nat. Med.
, vol.22
, pp. 879-888
-
-
Ryu, D.1
Mouchiroud, L.2
Andreux, P.A.3
Katsyuba, E.4
Moullan, N.5
Nicolet-Dit-Felix, A.A.6
Williams, E.G.7
Jha, P.8
Lo Sasso, G.9
Huzard, D.10
Aebischer, P.11
Sandi, C.12
Rinsch, C.13
Auwerx, J.14
-
56
-
-
0022924924
-
31P NMR spectroscopy, chemical analysis, and free Mg2+ of rabbit bladder and uterine smooth muscle
-
31P NMR spectroscopy, chemical analysis, and free Mg2+ of rabbit bladder and uterine smooth muscle. J. Biol. Chem. 261, 14420-14429 (1986).
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 14420-14429
-
-
Kushmerick, M.J.1
Dillon, P.F.2
Meyer, R.A.3
Brown, T.R.4
Krisanda, J.M.5
Sweeney, H.L.6
-
58
-
-
0026747626
-
High-performance liquid chromatographic assays for free and phosphorylated derivatives of the creatine analogues b-guanidopropionic acid and 1-carboxy-methyl-2-iminoimidazolidine (cyclocreatine)
-
R. W. Wiseman, T. S. Moerland, P. B. Chase, R. Stuppard, M. J. Kushmerick, High-performance liquid chromatographic assays for free and phosphorylated derivatives of the creatine analogues b-guanidopropionic acid and 1-carboxy-methyl-2-iminoimidazolidine (cyclocreatine). Anal. Biochem. 204, 383-389 (1992).
-
(1992)
Anal. Biochem.
, vol.204
, pp. 383-389
-
-
Wiseman, R.W.1
Moerland, T.S.2
Chase, P.B.3
Stuppard, R.4
Kushmerick, M.J.5
-
59
-
-
0025237134
-
NMR spectral analysis of kinetic data using natural lineshapes
-
F. W. Heineman, J. Eng, B. A. Berkowitz, R. S. Balaban, NMR spectral analysis of kinetic data using natural lineshapes. Magn. Reson. Med. 13, 490-497 (1990).
-
(1990)
Magn. Reson. Med.
, vol.13
, pp. 490-497
-
-
Heineman, F.W.1
Eng, J.2
Berkowitz, B.A.3
Balaban, R.S.4
|