SIRT1 protein, by blocking the activities of transcription factors FoxO1 and FoxO3, inhibits muscle atrophy and promotes muscle growth

Journal of Biological Chemistry

Volumn 288, Issue 42, 2013, Pages 30515-30526

  Lee, Donghoon ^a   Goldberg, Alfred L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DENERVATION; MUSCLE ATROPHY; MUSCLE GROWTH; MUSCLE SIZE; OVER-EXPRESSION; SKELETAL MUSCLE;

TRANSCRIPTION FACTORS;

MUSCLE;

ACYLTRANSFERASE; ATROGIN 1; DEACETYLASE; MUSCLE RING FINGER 1 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SIRTUIN 1; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATG GENE; CONTROLLED STUDY; DIET RESTRICTION; ELECTROPORATION; ENZYME ACTIVITY; FOOD DEPRIVATION; GENE; HEART MUSCLE; LIVER; MALE; MOUSE; MUSCLE ATROPHY; MUSCLE DENERVATION; MUSCLE GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SOLEUS MUSCLE; TIBIALIS ANTERIOR MUSCLE;

DEACETYLASE; FOXO; FOXO3; HYPERTROPHY; MUSCLE ATROPHY; SIRT1; SKELETAL MUSCLE; TRANSCRIPTION FACTORS;

ANIMALS; CACHEXIA; FASTING; FORKHEAD TRANSCRIPTION FACTORS; MALE; MICE; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SIRTUIN 1; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN-PROTEIN LIGASES;

EID: 84886899121     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.489716     Document Type: Article

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