Impaired adaptability of in vivo mitochondrial energetics to acute oxidative insult in aged skeletal muscle

Mechanisms of Ageing and Development

Volumn 133, Issue 9-10, 2012, Pages 620-628

  Siegel, Michael P ^a   Wilbur, Tim ^b   Mathis, Mark ^b   Shankland, Eric G ^b   Trieu, Atlas ^b   Harper, Mary Ellen ^c   Marcinek, David J ^a,b  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Mitochondria; Oxidative stress; Skeletal muscle; UCP3; Uncoupling

Indexed keywords

ADENOSINE TRIPHOSPHATE; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 3;

ADAPTATION; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HOMEOSTASIS; IN VIVO STUDY; MITOCHONDRIAL ENERGY TRANSFER; MOUSE; NEAR INFRARED SPECTROSCOPY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN CONCENTRATION; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SKELETAL MUSCLE; SPECTROSCOPY;

ADENOSINE TRIPHOSPHATE; AGING; ANIMALS; FEMALE; ION CHANNELS; MICE; MICE, KNOCKOUT; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN; REACTIVE OXYGEN SPECIES; REGENERATION;

MUS;

EID: 84866546747     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2012.08.002     Document Type: Article

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