Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

Neuron

Volumn 91, Issue 1, 2016, Pages 41-55

  Lee, Sebum ^a   Shang, Yulei ^a   Redmond, Stephanie A ^a,b   Urisman, Anatoly ^a   Tang, Amy A ^a   Li, Kathy H ^b   Burlingame, Alma L ^b   Pak, Ryan A ^a   Jovičić, Ana ^c   Gitler, Aaron D ^c   Wang, Jinhua ^d   Gray, Nathanael S ^d   Seeley, William W ^a   Siddique, Teepu ^e   Bigio, Eileen H ^e   Lee, Virginia M Y ^f   Trojanowski, John Q ^f   Chan, Jonah R ^a,b   Huang, Eric J ^a,b,g  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e NORTHWESTERN UNIVERSITY   (United States)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; BIOLOGICAL MARKER; COPPER ZINC SUPEROXIDE DISMUTASE; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; PROTEIN IRE1; STRESS ACTIVATED PROTEIN KINASE; TAR DNA BINDING PROTEIN; TUNICAMYCIN; CARRIER PROTEIN; DNA BINDING PROTEIN; HIPK2 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; SUPEROXIDE DISMUTASE; TDP-43 PROTEIN, MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG TARGETING; EMBRYO; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GLIA CELL; HUMAN; HUMAN TISSUE; MOUSE; MSOD1 MOUSE; NERVE REGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN MISFOLDING; PROTEIN PHOSPHORYLATION; SPINAL CORD MOTONEURON; SURVIVAL; ANIMAL; DISEASE MODEL; ENDOPLASMIC RETICULUM; GENETICS; GLIA; METABOLISM; MOTONEURON; PATHOLOGY; SPINAL CORD; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BIOMARKERS; CARRIER PROTEINS; CELL DEATH; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; MICE, TRANSGENIC; MOTOR NEURONS; NEUROGLIA; PROTEIN-SERINE-THREONINE KINASES; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 84991222851     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2016.05.021     Document Type: Article

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