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Volumn 128, Issue 3, 2014, Pages 423-437

TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord

Author keywords

Amyotrophic lateral sclerosis; Neurodegeneration; Oligodendroglia; Onuf's nucleus; Spinal cord; TDP 43

Indexed keywords

TAR DNA BINDING PROTEIN; ALPHA SYNUCLEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CLAUDIN; CLDN11 PROTEIN, HUMAN; DNA BINDING PROTEIN; NERVE PROTEIN; OLIG2 PROTEIN, HUMAN; PROTEIN TDP-43; TAU PROTEIN;

EID: 84906314307     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-014-1299-6     Document Type: Article
Times cited : (212)

References (63)
  • 1
    • 33749150163 scopus 로고    scopus 로고
    • Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
    • DOI 10.1007/s00401-006-0127-z
    • Braak H, Alafuzoff I, Arzberger T et al (2006) Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol 112:389-404 (Pubitemid 44469160)
    • (2006) Acta Neuropathologica , vol.112 , Issue.4 , pp. 389-404
    • Braak, H.1    Alafuzoff, I.2    Arzberger, T.3    Kretzschmar, H.4    Tredici, K.5
  • 2
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E (1991) Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82:239-259
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 3
    • 84890121734 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis-a model of corticofugal axonal spread
    • Braak H, Brettschneider J, Ludolph AC et al (2013) Amyotrophic lateral sclerosis-a model of corticofugal axonal spread. Nat Rev Neurol 9:708-714
    • (2013) Nat Rev Neurol , vol.9 , pp. 708-714
    • Braak, H.1    Brettschneider, J.2    Ludolph, A.C.3
  • 4
    • 79451471618 scopus 로고    scopus 로고
    • The pathological process underlying Alzheimer's disease in individuals under thirty
    • Braak H, Del Tredici K (2011) The pathological process underlying Alzheimer's disease in individuals under thirty. Acta Neuropathol 121:171-181
    • (2011) Acta Neuropathol , vol.121 , pp. 171-181
    • Braak, H.1    Del Tredici, K.2
  • 5
    • 84870004031 scopus 로고    scopus 로고
    • Where, when, and in what form does sporadic Alzheimer's disease begin?
    • Braak H, Del Tredici K (2012) Where, when, and in what form does sporadic Alzheimer's disease begin? Curr Opin Neurol 25:708-714
    • (2012) Curr Opin Neurol , vol.25 , pp. 708-714
    • Braak, H.1    Del Tredici, K.2
  • 6
    • 0037333666 scopus 로고    scopus 로고
    • Staging of brain pathology related to sporadic Parkinson's disease
    • DOI 10.1016/S0197-4580(02)00065-9, PII S0197458002000659
    • Braak H, Del Tredici K, Rüb U et al (2003) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24:197-211 (Pubitemid 36007810)
    • (2003) Neurobiology of Aging , vol.24 , Issue.2 , pp. 197-211
    • Braak, H.1    Del, T.K.2    Rub, U.3    De Vos, R.A.I.4    Jansen, S.E.N.H.5    Braak, E.6
  • 7
    • 77953870938 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: Dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord
    • Braak H, Ludolph A, Thal DR et al (2010) Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord. Acta Neuropathol 120:67-74
    • (2010) Acta Neuropathol , vol.120 , pp. 67-74
    • Braak, H.1    Ludolph, A.2    Thal, D.R.3
  • 8
    • 84896726031 scopus 로고    scopus 로고
    • Sequential distribution of pTDP-43 pathology in behavioral variant fronto-temporal dementia (bvFTD)
    • Brettschneider J, Del Tredici K, Irwin DJ et al (2014) Sequential distribution of pTDP-43 pathology in behavioral variant fronto-temporal dementia (bvFTD). Acta Neuropathol 127:423-439
    • (2014) Acta Neuropathol , vol.127 , pp. 423-439
    • Brettschneider, J.1    Del Tredici, K.2    Irwin, D.J.3
  • 9
    • 84883292041 scopus 로고    scopus 로고
    • Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
    • Brettschneider J, Del Tredici K, Toledo JB et al (2013) Stages of pTDP-43 pathology in amyotrophic lateral sclerosis. Ann Neurol 74:20-38
    • (2013) Ann Neurol , vol.74 , pp. 20-38
    • Brettschneider, J.1    Del Tredici, K.2    Toledo, J.B.3
  • 10
    • 84857918252 scopus 로고    scopus 로고
    • Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis
    • Brettschneider J, Libon DJ, Toledo JB et al (2012) Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis. Acta Neuropathol 123:395-407
    • (2012) Acta Neuropathol , vol.123 , pp. 395-407
    • Brettschneider, J.1    Libon, D.J.2    Toledo, J.B.3
  • 11
    • 84862245802 scopus 로고    scopus 로고
    • Microglial activation correlates with disease progression and upper motor neuron clinical symptoms in amyotrophic lateral sclerosis
    • Brettschneider J, Toledo JB, Van Deerlin VM et al (2012) Microglial activation correlates with disease progression and upper motor neuron clinical symptoms in amyotrophic lateral sclerosis. PLoS One 7:e39216
    • (2012) PLoS One , vol.7
    • Brettschneider, J.1    Toledo, J.B.2    Van Deerlin, V.M.3
  • 12
    • 84862756869 scopus 로고    scopus 로고
    • Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion
    • Brettschneider J, Van Deerlin VM, Robinson JL et al (2012) Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion. Acta Neuropathol 123:825-839
    • (2012) Acta Neuropathol , vol.123 , pp. 825-839
    • Brettschneider, J.1    Van Deerlin, V.M.2    Robinson, J.L.3
  • 13
  • 14
    • 0015962920 scopus 로고
    • Rubrospinal projections in the rat
    • Brown LT (1974) Rubrospinal projections in the rat. J Comp Neurol 154:169-187
    • (1974) J Comp Neurol , vol.154 , pp. 169-187
    • Brown, L.T.1
  • 16
    • 84857054634 scopus 로고    scopus 로고
    • Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72
    • Cooper-Knock J, Hewitt C, Highley JR et al (2012) Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72. Brain 135:751-764
    • (2012) Brain , vol.135 , pp. 751-764
    • Cooper-Knock, J.1    Hewitt, C.2    Highley, J.R.3
  • 17
    • 78650445324 scopus 로고    scopus 로고
    • Eye movements in amyotrophic lateral sclerosis and its mimics: A review with illustrative cases
    • Donaghy C, Thurtell MJ, Pioro EP et al (2011) Eye movements in amyotrophic lateral sclerosis and its mimics: a review with illustrative cases. J Neurol Neurosurg Psychiatry 82:110-116
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , pp. 110-116
    • Donaghy, C.1    Thurtell, M.J.2    Pioro, E.P.3
  • 18
    • 0036322266 scopus 로고    scopus 로고
    • Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases
    • DOI 10.1002/ana.10279
    • Duda JE, Giasson BI, Mabon ME et al (2002) Novel antibodies to synuclein show abundant striatal pathology in Lewy body diseases. Ann Neurol 52:205-210 (Pubitemid 34810601)
    • (2002) Annals of Neurology , vol.52 , Issue.2 , pp. 205-210
    • Duda, J.E.1    Giasson, B.I.2    Mabon, M.E.3    Lee, V.M.-Y.4    Trojanowski, J.Q.5
  • 19
    • 84865063851 scopus 로고    scopus 로고
    • The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth
    • Fallini C, Bassell GJ, Rossoll W (2012) The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth. Hum Mol Genet 21:3703-3718
    • (2012) Hum Mol Genet , vol.21 , pp. 3703-3718
    • Fallini, C.1    Bassell, G.J.2    Rossoll, W.3
  • 20
    • 84877125251 scopus 로고    scopus 로고
    • Paraffin sections of 70-100 mum: A novel technique and its benefits for studying the nervous system
    • Feldengut S, Del Tredici K, Braak H (2013) Paraffin sections of 70-100 mum: a novel technique and its benefits for studying the nervous system. J Neurosci Methods 215:241-244
    • (2013) J Neurosci Methods , vol.215 , pp. 241-244
    • Feldengut, S.1    Del Tredici, K.2    Braak, H.3
  • 22
    • 60549117972 scopus 로고    scopus 로고
    • Clinical and pathological continuum of multisystem TDP-43 proteinopathies
    • .Geser F, Martinez-Lage M, Robinson J et al (2009) Clinical and pathological continuum of multisystem TDP-43 proteinopathies. Arch Neurol 66:180-189
    • (2009) Arch Neurol , vol.66 , pp. 180-189
    • Geser, F.1    Martinez-Lage, M.2    Robinson, J.3
  • 23
    • 84893642253 scopus 로고    scopus 로고
    • Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases
    • .Guo JL, Lee VM (2014) Cell-to-cell transmission of pathogenic proteins in neurodegenerative diseases. Nat Med 20:130-138
    • (2014) Nat Med , vol.20 , pp. 130-138
    • Guo, J.L.1    Lee, V.M.2
  • 24
    • 0018319649 scopus 로고
    • Amyotrophic lateral sclerosis with ophthalmoplegia. A clinicopathologic study
    • Harvey DG, Torack RM, Rosenbaum HE (1979) Amyotrophic lateral sclerosis with ophthalmoplegia. A clinicopathologic study. Arch Neurol 36:615-617 (Pubitemid 9247534)
    • (1979) Archives of Neurology , vol.36 , Issue.10 , pp. 615-617
    • Harvey, D.G.1    Torack, R.M.2    Rosenbaum, H.E.3
  • 25
    • 0242347594 scopus 로고    scopus 로고
    • Defining the NG2-expressing cell of the adult CNS
    • DOI 10.1023/A:1025739630398
    • Horner PJ, Thallmair M, Gage FH (2002) Defining the NG2- expressing cell of the adult CNS. J Neurocytol 31:469-480 (Pubitemid 37378259)
    • (2002) Journal of Neurocytology , vol.31 , Issue.6-7 , pp. 469-480
    • Borner, P.J.1    Thallmair, M.2    Gage, F.H.3
  • 27
    • 0020549545 scopus 로고
    • Principles of motor organization of the monkey cervical spinal cord
    • Jenny AB, Inukai J (1983) Principles of motor organization of the monkey cervical spinal cord. J Neurosci 3:567-575 (Pubitemid 13132721)
    • (1983) Journal of Neuroscience , vol.3 , Issue.3 , pp. 567-575
    • Jenny, A.B.1    Inukai, J.2
  • 28
    • 84883688262 scopus 로고    scopus 로고
    • Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
    • Jucker M, Walker LC (2013) Self-propagation of pathogenic protein aggregates in neurodegenerative diseases. Nature 501:45-51
    • (2013) Nature , vol.501 , pp. 45-51
    • Jucker, M.1    Walker, L.C.2
  • 29
    • 84876900163 scopus 로고    scopus 로고
    • Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
    • Kang SH, Li Y, Fukaya M et al (2013) Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat Neurosci 16:571-579
    • (2013) Nat Neurosci , vol.16 , pp. 571-579
    • Kang, S.H.1    Li, Y.2    Fukaya, M.3
  • 30
    • 84870994113 scopus 로고    scopus 로고
    • Coaggregation of RNA binding proteins in ALS spinal motor neurons: Evidence of a common pathogenic mechanism
    • Keller BA, Volkening K, Droppelmann CA et al (2012) Coaggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism. Acta Neuropathol 124:733-747
    • (2012) Acta Neuropathol , vol.124 , pp. 733-747
    • Keller, B.A.1    Volkening, K.2    Droppelmann, C.A.3
  • 31
    • 79952486262 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis
    • Kiernan MC, Vucic S, Cheah BC et al (2011) Amyotrophic lateral sclerosis. Lancet 377:942-955
    • (2011) Lancet , vol.377 , pp. 942-955
    • Kiernan, M.C.1    Vucic, S.2    Cheah, B.C.3
  • 32
    • 84906095611 scopus 로고    scopus 로고
    • Bunina bodies in motor and non-motor neurons revisited: A pathological study of an ALS patient after long-term survival on a respirator
    • Kimura T, Jiang H, Konno T et al. (2014) Bunina bodies in motor and non-motor neurons revisited: a pathological study of an ALS patient after long-term survival on a respirator. Neuropathology
    • (2014) Neuropathology
    • Kimura, T.1    Jiang, H.2    Konno, T.3
  • 33
    • 0027984748 scopus 로고
    • Motor neuron disease with dementia and ophthalmoplegia. A clinical and pathological study
    • DOI 10.1007/BF00920622
    • Komachi H, Okeda R, Ishii N et al (1994) Motor neuron disease with dementia and ophthalmoplegia. A clinical and pathological study. J Neurol 241:592-596 (Pubitemid 24309916)
    • (1994) Journal of Neurology , vol.241 , Issue.10 , pp. 592-596
    • Komachi, H.1    Okeda, R.2    Ishii, N.3    Yanagisawa, K.4    Yamada, M.5    Miyatake, T.6
  • 34
    • 84155167265 scopus 로고    scopus 로고
    • Gains or losses: Molecular mechanisms of TDP43-mediated neurodegeneration
    • Lee EB, Lee VM, Trojanowski JQ (2012) Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration. Nat Rev Neurosci 13:38-50
    • (2012) Nat Rev Neurosci , vol.13 , pp. 38-50
    • Lee, E.B.1    Lee, V.M.2    Trojanowski, J.Q.3
  • 35
    • 33645220400 scopus 로고    scopus 로고
    • Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice
    • DOI 10.1074/jbc.M511018200
    • Lee EB, Leng LZ, Zhang B et al (2006) Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. J Biol Chem 281:4292-4299 (Pubitemid 43847859)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.7 , pp. 4292-4299
    • Lee, E.B.1    Leng, L.Z.2    Zhang, B.3    Kwong, L.4    Trojanowski, J.Q.5    Abel, T.6    Lee, V.M.-Y.7
  • 36
    • 84864200035 scopus 로고    scopus 로고
    • Oligodendroglia metabolically support axons and contribute to neurodegeneration
    • Lee Y, Morrison BM, Li Y et al (2012) Oligodendroglia metabolically support axons and contribute to neurodegeneration. Nature 487:443-448
    • (2012) Nature , vol.487 , pp. 443-448
    • Lee, Y.1    Morrison, B.M.2    Li, Y.3
  • 37
    • 84881490873 scopus 로고    scopus 로고
    • Converging mechanisms in ALS and FTD: Disrupted RNA and protein homeostasis
    • Ling SC, Polymenidou M, Cleveland DW (2013) Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis. Neuron 79:416-438
    • (2013) Neuron , vol.79 , pp. 416-438
    • Ling, S.C.1    Polymenidou, M.2    Cleveland, D.W.3
  • 38
    • 77949888316 scopus 로고    scopus 로고
    • Sporadic amyotrophic lateral sclerosis with pallido-nigro-luysian degeneration: A TDP- 43 immunohistochemical study
    • Miki Y, Mori F, Nunomura J et al (2010) Sporadic amyotrophic lateral sclerosis with pallido-nigro-luysian degeneration: a TDP- 43 immunohistochemical study. Neuropathology 30:149-153
    • (2010) Neuropathology , vol.30 , pp. 149-153
    • Miki, Y.1    Mori, F.2    Nunomura, J.3
  • 39
    • 84858000548 scopus 로고    scopus 로고
    • Comparison of phosphorylated TDP-43-positive inclusions in oculomotor neurons in patients with non-ALS and ALS disorders
    • Mizuno Y, Fujita Y, Takatama M et al (2012) Comparison of phosphorylated TDP-43-positive inclusions in oculomotor neurons in patients with non-ALS and ALS disorders. J Neurol Sci 315:20-25
    • (2012) J Neurol Sci , vol.315 , pp. 20-25
    • Mizuno, Y.1    Fujita, Y.2    Takatama, M.3
  • 40
    • 47949099336 scopus 로고    scopus 로고
    • Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia
    • Mori F, Tanji K, Zhang HX et al (2008) Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol 116:193-203
    • (2008) Acta Neuropathol , vol.116 , pp. 193-203
    • Mori, F.1    Tanji, K.2    Zhang, H.X.3
  • 42
    • 57049139889 scopus 로고    scopus 로고
    • Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology
    • Nishihira Y, Tan CF, Hoshi Y et al (2009) Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology. Acta Neuropathol 117:45-53
    • (2009) Acta Neuropathol , vol.117 , pp. 45-53
    • Nishihira, Y.1    Tan, C.F.2    Hoshi, Y.3
  • 43
    • 47949096734 scopus 로고    scopus 로고
    • Sporadic amyotrophic lateral sclerosis: Two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions
    • Nishihira Y, Tan CF, Onodera O et al (2008) Sporadic amyotrophic lateral sclerosis: two pathological patterns shown by analysis of distribution of TDP-43-immunoreactive neuronal and glial cytoplasmic inclusions. Acta Neuropathol 116:169-182
    • (2008) Acta Neuropathol , vol.116 , pp. 169-182
    • Nishihira, Y.1    Tan, C.F.2    Onodera, O.3
  • 44
    • 84885484356 scopus 로고    scopus 로고
    • Prion-like properties of pathological TDP-43 aggregates from diseased brains
    • Nonaka T, Masuda-Suzukake M, Arai T et al (2013) Prion-like properties of pathological TDP-43 aggregates from diseased brains. Cell Rep 4:124-134
    • (2013) Cell Rep , vol.4 , pp. 124-134
    • Nonaka, T.1    Masuda-Suzukake, M.2    Arai, T.3
  • 45
    • 35248823549 scopus 로고    scopus 로고
    • Cognitive impairment in amyotrophic lateral sclerosis
    • DOI 10.1016/S1474-4422(07)70265-X, PII S147444220770265X
    • Phukan J, Pender NP, Hardiman O (2007) Cognitive impairment in amyotrophic lateral sclerosis. Lancet Neurol 6:994-1003 (Pubitemid 47562321)
    • (2007) Lancet Neurology , vol.6 , Issue.11 , pp. 994-1003
    • Phukan, J.1    Pender, N.P.2    Hardiman, O.3
  • 46
    • 34248202138 scopus 로고    scopus 로고
    • Focality of upper and lower motor neuron degeneration at the clinical onset of ALS
    • DOI 10.1212/01.wnl.0000260965.20021.47, PII 0000611420070508000005
    • Ravits J, Paul P, Jorg C (2007) Focality of upper and lower motor neuron degeneration at the clinical onset of ALS. Neurology 68:1571-1575 (Pubitemid 46717980)
    • (2007) Neurology , vol.68 , Issue.19 , pp. 1571-1575
    • Ravits, J.1    Paul, P.2    Jorg, C.3
  • 47
    • 70349581626 scopus 로고    scopus 로고
    • ALS motor phenotype heterogeneity, focality, and spread: Deconstructing motor neuron degeneration
    • Ravits JM, La Spada AR (2009) ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration. Neurology 73:805-811
    • (2009) Neurology , vol.73 , pp. 805-811
    • Ravits, J.M.1    La Spada, A.R.2
  • 48
    • 77049166450 scopus 로고
    • A cytoarchitectonic atlas of the spinal cord in the cat
    • Rexed B (1954) A cytoarchitectonic atlas of the spinal cord in the cat. J Comp Neurol 100:297-379
    • (1954) J Comp Neurol , vol.100 , pp. 297-379
    • Rexed, B.1
  • 49
    • 84893840409 scopus 로고    scopus 로고
    • Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • Riku Y, Watanabe H, Yoshida M et al (2014) Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis. JAMA Neurol 71:172-179
    • (2014) JAMA Neurol , vol.71 , pp. 172-179
    • Riku, Y.1    Watanabe, H.2    Yoshida, M.3
  • 50
    • 0032850739 scopus 로고    scopus 로고
    • A study of motoneuron groups and motor columns of the human spinal cord
    • DOI 10.1017/S002187829900521X
    • Routal RV, Pal GP (1999) A study of motoneuron groups and motor columns of the human spinal cord. J Anat 195(Pt 2):211-224 (Pubitemid 29452880)
    • (1999) Journal of Anatomy , vol.195 , Issue.2 , pp. 211-224
    • Routal, R.V.1    Pal, G.P.2
  • 51
    • 0035107248 scopus 로고    scopus 로고
    • How amyotrophic lateral sclerosis got its name: The clinical-pathologic genius of Jean-Martin Charcot
    • Rowland LP (2001) How amyotrophic lateral sclerosis got its name: the clinical-pathologic genius of Jean-Martin Charcot. Arch Neurol 58:512-515
    • (2001) Arch Neurol , vol.58 , pp. 512-515
    • Rowland, L.P.1
  • 52
    • 0020370761 scopus 로고
    • Dendritic organization of the human spinal cord: The motoneurons
    • Schoenen J (1982) Dendritic organization of the human spinal cord: the motoneurons. J Comp Neurol 211:226-247
    • (1982) J Comp Neurol , vol.211 , pp. 226-247
    • Schoenen, J.1
  • 53
    • 0000832727 scopus 로고
    • The distribution of the permanent paralysis in the lower limb in poliomyelitis: A clinical and pathological study
    • Sharrard WJ (1955) The distribution of the permanent paralysis in the lower limb in poliomyelitis: a clinical and pathological study. J Bone Jt Surg Br 37-B:540-558
    • (1955) J Bone Jt Surg Br , vol.37 B , pp. 540-558
    • Sharrard, W.J.1
  • 54
    • 84857921617 scopus 로고    scopus 로고
    • Clinical and pathological features of amyotrophic lateral sclerosis caused by mutation in the C9ORF72 gene on chromosome 9p
    • Stewart H, Rutherford NJ, Briemberg H et al (2012) Clinical and pathological features of amyotrophic lateral sclerosis caused by mutation in the C9ORF72 gene on chromosome 9p. Acta Neuropathol 123:409-417
    • (2012) Acta Neuropathol , vol.123 , pp. 409-417
    • Stewart, H.1    Rutherford, N.J.2    Briemberg, H.3
  • 55
    • 64049116333 scopus 로고    scopus 로고
    • Nuclear TAR DNA binding protein 43 expression in spinal cord neurons correlates with the clinical course in amyotrophic lateral sclerosis
    • Sumi H, Kato S, Mochimaru Y et al (2009) Nuclear TAR DNA binding protein 43 expression in spinal cord neurons correlates with the clinical course in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 68:37-47
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 37-47
    • Sumi, H.1    Kato, S.2    Mochimaru, Y.3
  • 56
    • 84906318887 scopus 로고    scopus 로고
    • Dendritic retraction, but not atrophy, is consistent in amyotrophic lateral sclerosis- comparison between Onuf's neurons and other sacral motor neurons
    • Takeda T, Uchihara T, Nakayama Y et al (2014) Dendritic retraction, but not atrophy, is consistent in amyotrophic lateral sclerosis- comparison between Onuf's neurons and other sacral motor neurons. Acta Neuropathol Commun 2:11
    • (2014) Acta Neuropathol Commun , vol.2 , pp. 11
    • Takeda, T.1    Uchihara, T.2    Nakayama, Y.3
  • 57
    • 0031867192 scopus 로고    scopus 로고
    • Origin, course, and laterality of spinocerebellar axons in the North American opossum, Didelphis virginiana
    • DOI 10.1002/(SICI)1097-0185(199808)251:4<528::AID
    • Terman JR, Wang XM, Martin GF (1998) Origin, course, and laterality of spinocerebellar axons in the North American opossum, Didelphis virginiana. Anat Rec 251:528-547 (Pubitemid 28366725)
    • (1998) Anatomical Record , vol.251 , Issue.4 , pp. 528-547
    • Terman, J.R.1    Wang, X.M.2    Martin, G.F.3
  • 58
    • 0037172826 scopus 로고    scopus 로고
    • Phases of Abeta-deposition in the human brain and its relevance for the development of AD
    • Thal DR, Rub U, Orantes M et al (2002) Phases of A beta-deposition in the human brain and its relevance for the development of AD. Neurology 58:1791-1800 (Pubitemid 34663580)
    • (2002) Neurology , vol.58 , Issue.12 , pp. 1791-1800
    • Thal, D.R.1    Rub, U.2    Orantes, M.3    Braak, H.4
  • 59
    • 84903744902 scopus 로고    scopus 로고
    • A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank
    • Toledo JB, Van Deerlin VM, Lee EB et al (2013) A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank. Alzheimers Dement
    • (2013) Alzheimers Dement
    • Toledo, J.B.1    Van Deerlin, V.M.2    Lee, E.B.3
  • 60
    • 84865068311 scopus 로고    scopus 로고
    • Hexanucleotide repeat expansions in C9ORF72 in the spectrum of motor neuron diseases
    • Van Rheenen W, Van Blitterswijk M, Huisman MH et al (2012) Hexanucleotide repeat expansions in C9ORF72 in the spectrum of motor neuron diseases. Neurology 79:878-882
    • (2012) Neurology , vol.79 , pp. 878-882
    • Van Rheenen, W.1    Van Blitterswijk, M.2    Huisman, M.H.3
  • 61
    • 0014594221 scopus 로고
    • Descending nerve tracts in the spinal cord of the rat. I. Fibers from the midbrain
    • Waldron HA, Gwyn DG (1969) Descending nerve tracts in the spinal cord of the rat. I. Fibers from the midbrain. J Comp Neurol 137:143-153
    • (1969) J Comp Neurol , vol.137 , pp. 143-153
    • Waldron, H.A.1    Gwyn, D.G.2
  • 62
    • 79960824615 scopus 로고    scopus 로고
    • Building an integrated neurodegenerative disease database at an academic health center
    • Xie SX, Baek Y, Grossman M et al (2011) Building an integrated neurodegenerative disease database at an academic health center. Alzheimers Dement 7:e84-e93
    • (2011) Alzheimers Dement , vol.7
    • Xie, S.X.1    Baek, Y.2    Grossman, M.3
  • 63
    • 36949008994 scopus 로고    scopus 로고
    • TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia
    • DOI 10.1007/s00401-007-0285-7
    • Zhang H, Tan CF, Mori F et al (2008) TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol 115:115-122 (Pubitemid 350238670)
    • (2008) Acta Neuropathologica , vol.115 , Issue.1 , pp. 115-122
    • Zhang, H.1    Tan, C.-F.2    Mori, F.3    Tanji, K.4    Kakita, A.5    Takahashi, H.6    Wakabayashi, K.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.