메뉴 건너뛰기




Volumn 11, Issue 4, 2013, Pages

Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis Via TGF-β-TAK1-Dependent Mechanism

Author keywords

[No Author keywords available]

Indexed keywords

COREPRESSOR PROTEIN; HIPK1 PROTEIN; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; HOMEODOMAIN PROTEIN; PROTEIN KINASE; SMALL INTERFERING RNA; STROMELYSIN 2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TYROSINE; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84876961787     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001527     Document Type: Article
Times cited : (50)

References (47)
  • 1
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P, (2005) Angiogenesis in life, disease and medicine. Nature 438: 932-936.
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 3
    • 30744432619 scopus 로고    scopus 로고
    • Endothelial cells and VEGF in vascular development
    • Coultas L, Chawengsaksophak K, Rossant J, (2005) Endothelial cells and VEGF in vascular development. Nature 438: 937-945.
    • (2005) Nature , vol.438 , pp. 937-945
    • Coultas, L.1    Chawengsaksophak, K.2    Rossant, J.3
  • 4
    • 18344377007 scopus 로고    scopus 로고
    • Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
    • You LR, Lin FJ, Lee CT, DeMayo FJ, Tsai MJ, et al. (2005) Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature 435: 98-104.
    • (2005) Nature , vol.435 , pp. 98-104
    • You, L.R.1    Lin, F.J.2    Lee, C.T.3    DeMayo, F.J.4    Tsai, M.J.5
  • 5
    • 77649252156 scopus 로고    scopus 로고
    • COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis
    • Qin J, Chen X, Xie X, Tsai MJ, Tsai SY, (2010) COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A 107: 3687-3692.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 3687-3692
    • Qin, J.1    Chen, X.2    Xie, X.3    Tsai, M.J.4    Tsai, S.Y.5
  • 6
    • 0034644472 scopus 로고    scopus 로고
    • TGFbeta signaling in growth control, cancer, and heritable disorders
    • Massague J, Blain SW, Lo RS, (2000) TGFbeta signaling in growth control, cancer, and heritable disorders. Cell 103: 295-309.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 7
    • 77956187467 scopus 로고    scopus 로고
    • Signaling by members of the TGF-beta family in vascular morphogenesis and disease
    • Pardali E, Goumans MJ, ten Dijke P, (2010) Signaling by members of the TGF-beta family in vascular morphogenesis and disease. Trends Cell Biol 20: 556-567.
    • (2010) Trends Cell Biol , vol.20 , pp. 556-567
    • Pardali, E.1    Goumans, M.J.2    ten Dijke, P.3
  • 8
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of TGFbeta signal transduction
    • Moustakas A, Heldin CH, (2009) The regulation of TGFbeta signal transduction. Development 136: 3699-3714.
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.H.2
  • 9
    • 35448991324 scopus 로고    scopus 로고
    • Extracellular control of TGFbeta signalling in vascular development and disease
    • ten Dijke P, Arthur HM, (2007) Extracellular control of TGFbeta signalling in vascular development and disease. Nat Rev Mol Cell Biol 8: 857-869.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 857-869
    • ten Dijke, P.1    Arthur, H.M.2
  • 10
    • 0242330126 scopus 로고    scopus 로고
    • Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling
    • Goumans MJ, Valdimarsdottir G, Itoh S, Lebrin F, Larsson J, et al. (2003) Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling. Mol Cell 12: 817-828.
    • (2003) Mol Cell , vol.12 , pp. 817-828
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3    Lebrin, F.4    Larsson, J.5
  • 11
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
    • Goumans MJ, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, et al. (2002) Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J 21: 1743-1753.
    • (2002) EMBO J , vol.21 , pp. 1743-1753
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3    Rosendahl, A.4    Sideras, P.5
  • 12
  • 13
    • 33845889727 scopus 로고    scopus 로고
    • Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons
    • Zhang J, Pho V, Bonasera SJ, Holzmann J, Tang AT, et al. (2007) Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons. Nat Neurosci 10: 77-86.
    • (2007) Nat Neurosci , vol.10 , pp. 77-86
    • Zhang, J.1    Pho, V.2    Bonasera, S.J.3    Holzmann, J.4    Tang, A.T.5
  • 14
    • 80053233160 scopus 로고    scopus 로고
    • Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling
    • Chalazonitis A, Tang AA, Shang Y, Pham TD, Hsieh I, et al. (2011) Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling. J Neurosci 31: 13746-13757.
    • (2011) J Neurosci , vol.31 , pp. 13746-13757
    • Chalazonitis, A.1    Tang, A.A.2    Shang, Y.3    Pham, T.D.4    Hsieh, I.5
  • 15
    • 0141866703 scopus 로고    scopus 로고
    • Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation
    • Harada J, Kokura K, Kanei-Ishii C, Nomura T, Khan MM, et al. (2003) Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation. J Biol Chem 278: 38998-39005.
    • (2003) J Biol Chem , vol.278 , pp. 38998-39005
    • Harada, J.1    Kokura, K.2    Kanei-Ishii, C.3    Nomura, T.4    Khan, M.M.5
  • 16
    • 0345734277 scopus 로고    scopus 로고
    • HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells
    • Hofmann TG, Stollberg N, Schmitz ML, Will H, (2003) HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells. Cancer Res 63: 8271-8277.
    • (2003) Cancer Res , vol.63 , pp. 8271-8277
    • Hofmann, T.G.1    Stollberg, N.2    Schmitz, M.L.3    Will, H.4
  • 17
    • 84859589441 scopus 로고    scopus 로고
    • A systems approach identifies HIPK2 as a key regulator of kidney fibrosis
    • Jin Y, Ratnam K, Chuang PY, Fan Y, Zhong Y, et al. (2012) A systems approach identifies HIPK2 as a key regulator of kidney fibrosis. Nature Medicine 18: 580-588.
    • (2012) Nature Medicine , vol.18 , pp. 580-588
    • Jin, Y.1    Ratnam, K.2    Chuang, P.Y.3    Fan, Y.4    Zhong, Y.5
  • 18
    • 0037627405 scopus 로고    scopus 로고
    • Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1)
    • Kondo S, Lu Y, Debbas M, Lin AW, Sarosi I, et al. (2003) Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). Proc Natl Acad Sci U S A 100: 5431-5436.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5431-5436
    • Kondo, S.1    Lu, Y.2    Debbas, M.3    Lin, A.W.4    Sarosi, I.5
  • 19
    • 33645238760 scopus 로고    scopus 로고
    • Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals
    • Isono K, Nemoto K, Li Y, Takada Y, Suzuki R, et al. (2006) Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol Cell Biol 26: 2758-2771.
    • (2006) Mol Cell Biol , vol.26 , pp. 2758-2771
    • Isono, K.1    Nemoto, K.2    Li, Y.3    Takada, Y.4    Suzuki, R.5
  • 20
    • 33748372107 scopus 로고    scopus 로고
    • Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation
    • Aikawa Y, Nguyen LA, Isono K, Takakura N, Tagata Y, et al. (2006) Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation. EMBO J 25: 3955-3965.
    • (2006) EMBO J , vol.25 , pp. 3955-3965
    • Aikawa, Y.1    Nguyen, L.A.2    Isono, K.3    Takakura, N.4    Tagata, Y.5
  • 21
    • 0035911151 scopus 로고    scopus 로고
    • The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies
    • Bajou K, Masson V, Gerard RD, Schmitt PM, Albert V, et al. (2001) The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. J Cell Biol 152: 777-784.
    • (2001) J Cell Biol , vol.152 , pp. 777-784
    • Bajou, K.1    Masson, V.2    Gerard, R.D.3    Schmitt, P.M.4    Albert, V.5
  • 22
    • 0028582034 scopus 로고
    • Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
    • Guan KL, Jenkins CW, Li Y, Nichols MA, Wu X, et al. (1994) Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev 8: 2939-2952.
    • (1994) Genes Dev , vol.8 , pp. 2939-2952
    • Guan, K.L.1    Jenkins, C.W.2    Li, Y.3    Nichols, M.A.4    Wu, X.5
  • 23
    • 0032569888 scopus 로고    scopus 로고
    • Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins
    • Zariwala M, Liu J, Xiong Y, (1998) Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins. Oncogene 17: 2787-2798.
    • (1998) Oncogene , vol.17 , pp. 2787-2798
    • Zariwala, M.1    Liu, J.2    Xiong, Y.3
  • 24
    • 51949098691 scopus 로고    scopus 로고
    • PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex
    • Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, et al. (2008) PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev 22: 2496-2506.
    • (2008) Genes Dev , vol.22 , pp. 2496-2506
    • Abbas, T.1    Sivaprasad, U.2    Terai, K.3    Amador, V.4    Pagano, M.5
  • 25
    • 33746228132 scopus 로고    scopus 로고
    • Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10
    • Chang S, Young BD, Li S, Qi X, Richardson JA, et al. (2006) Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell 126: 321-334.
    • (2006) Cell , vol.126 , pp. 321-334
    • Chang, S.1    Young, B.D.2    Li, S.3    Qi, X.4    Richardson, J.A.5
  • 26
    • 33646713486 scopus 로고    scopus 로고
    • The TGF beta activated kinase TAK1 regulates vascular development in vivo
    • Jadrich JL, O'Connor MB, Coucouvanis E, (2006) The TGF beta activated kinase TAK1 regulates vascular development in vivo. Development 133: 1529-1541.
    • (2006) Development , vol.133 , pp. 1529-1541
    • Jadrich, J.L.1    O'Connor, M.B.2    Coucouvanis, E.3
  • 27
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, et al. (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380: 435-439.
    • (1996) Nature , vol.380 , pp. 435-439
    • Carmeliet, P.1    Ferreira, V.2    Breier, G.3    Pollefeyt, S.4    Kieckens, L.5
  • 28
    • 0030004485 scopus 로고    scopus 로고
    • Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
    • Ferrara N, Carver-Moore K, Chen H, Dowd M, Lu L, et al. (1996) Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380: 439-442.
    • (1996) Nature , vol.380 , pp. 439-442
    • Ferrara, N.1    Carver-Moore, K.2    Chen, H.3    Dowd, M.4    Lu, L.5
  • 29
    • 0034667792 scopus 로고    scopus 로고
    • Orchestrated response: a symphony of transcription factors for gene control
    • Lemon B, Tjian R, (2000) Orchestrated response: a symphony of transcription factors for gene control. Genes & Development 14: 2551-2569.
    • (2000) Genes & Development , vol.14 , pp. 2551-2569
    • Lemon, B.1    Tjian, R.2
  • 30
    • 11144355861 scopus 로고    scopus 로고
    • Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK
    • Kanei-Ishii C, Ninomiya-Tsuji J, Tanikawa J, Nomura T, Ishitani T, et al. (2004) Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK. Genes Dev 18: 816-829.
    • (2004) Genes Dev , vol.18 , pp. 816-829
    • Kanei-Ishii, C.1    Ninomiya-Tsuji, J.2    Tanikawa, J.3    Nomura, T.4    Ishitani, T.5
  • 31
    • 26244448504 scopus 로고    scopus 로고
    • The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3
    • Kurahashi T, Nomura T, Kanei-Ishii C, Shinkai Y, Ishii S, (2005) The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3. Mol Biol Cell 16: 4705-4713.
    • (2005) Mol Biol Cell , vol.16 , pp. 4705-4713
    • Kurahashi, T.1    Nomura, T.2    Kanei-Ishii, C.3    Shinkai, Y.4    Ishii, S.5
  • 32
    • 53349164136 scopus 로고    scopus 로고
    • The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
    • Sorrentino A, Thakur N, Grimsby S, Marcusson A, von Bulow V, et al. (2008) The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner. Nat Cell Biol 10: 1199-1207.
    • (2008) Nat Cell Biol , vol.10 , pp. 1199-1207
    • Sorrentino, A.1    Thakur, N.2    Grimsby, S.3    Marcusson, A.4    von Bulow, V.5
  • 33
    • 0029551805 scopus 로고
    • Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
    • Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, et al. (1995) Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 270: 2008-2011.
    • (1995) Science , vol.270 , pp. 2008-2011
    • Yamaguchi, K.1    Shirakabe, K.2    Shibuya, H.3    Irie, K.4    Oishi, I.5
  • 34
    • 52049111663 scopus 로고    scopus 로고
    • TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta
    • Yamashita M, Fatyol K, Jin C, Wang X, Liu Z, et al. (2008) TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta. Mol Cell 31: 918-924.
    • (2008) Mol Cell , vol.31 , pp. 918-924
    • Yamashita, M.1    Fatyol, K.2    Jin, C.3    Wang, X.4    Liu, Z.5
  • 35
    • 0038351964 scopus 로고    scopus 로고
    • A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta
    • Ono K, Ohtomo T, Ninomiya-Tsuji J, Tsuchiya M, (2003) A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta. Biochem Biophys Res Commun 307: 332-337.
    • (2003) Biochem Biophys Res Commun , vol.307 , pp. 332-337
    • Ono, K.1    Ohtomo, T.2    Ninomiya-Tsuji, J.3    Tsuchiya, M.4
  • 37
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
    • Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, et al. (2001) Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocrine Reviews 22: 153-183.
    • (2001) Endocrine Reviews , vol.22 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Beers Gibson, T.3    Xu, B.E.4    Karandikar, M.5
  • 38
    • 29944436856 scopus 로고    scopus 로고
    • Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation
    • Braren R, Hu H, Kim YH, Beggs HE, Reichardt LF, et al. (2006) Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation. J Cell Biol 172: 151-162.
    • (2006) J Cell Biol , vol.172 , pp. 151-162
    • Braren, R.1    Hu, H.2    Kim, Y.H.3    Beggs, H.E.4    Reichardt, L.F.5
  • 39
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE, (2003) Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425: 577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 40
    • 0037431130 scopus 로고    scopus 로고
    • Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis
    • Gong X, Tang X, Wiedmann M, Wang X, Peng J, et al. (2003) Cdk5-mediated inhibition of the protective effects of transcription factor MEF2 in neurotoxicity-induced apoptosis. Neuron 38: 33-46.
    • (2003) Neuron , vol.38 , pp. 33-46
    • Gong, X.1    Tang, X.2    Wiedmann, M.3    Wang, X.4    Peng, J.5
  • 41
    • 70450255113 scopus 로고    scopus 로고
    • Phosphorylation of neuronal survival factor MEF2D by glycogen synthase kinase 3beta in neuronal apoptosis
    • Wang X, She H, Mao Z, (2009) Phosphorylation of neuronal survival factor MEF2D by glycogen synthase kinase 3beta in neuronal apoptosis. J Biol Chem 284: 32619-32626.
    • (2009) J Biol Chem , vol.284 , pp. 32619-32626
    • Wang, X.1    She, H.2    Mao, Z.3
  • 42
    • 20144379460 scopus 로고    scopus 로고
    • Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1)
    • Pardali K, Kowanetz M, Heldin CH, Moustakas A, (2005) Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1). Journal of Cellular Physiology 204: 260-272.
    • (2005) Journal of Cellular Physiology , vol.204 , pp. 260-272
    • Pardali, K.1    Kowanetz, M.2    Heldin, C.H.3    Moustakas, A.4
  • 43
    • 7244223245 scopus 로고    scopus 로고
    • Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival
    • Wiggins AK, Wei G, Doxakis E, Wong C, Tang AA, et al. (2004) Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival. J Cell Biol 167: 257-267.
    • (2004) J Cell Biol , vol.167 , pp. 257-267
    • Wiggins, A.K.1    Wei, G.2    Doxakis, E.3    Wong, C.4    Tang, A.A.5
  • 44
    • 27344444684 scopus 로고    scopus 로고
    • Vascular development of the brain requires beta8 integrin expression in the neuroepithelium
    • Proctor JM, Zang K, Wang D, Wang R, Reichardt LF, (2005) Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J Neurosci 25: 9940-9948.
    • (2005) J Neurosci , vol.25 , pp. 9940-9948
    • Proctor, J.M.1    Zang, K.2    Wang, D.3    Wang, R.4    Reichardt, L.F.5
  • 45
    • 0036199441 scopus 로고    scopus 로고
    • Conditional inactivation of the TGF-beta type II receptor using Cre:Lox
    • Chytil A, Magnuson MA, Wright CV, Moses HL, (2002) Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis 32: 73-75.
    • (2002) Genesis , vol.32 , pp. 73-75
    • Chytil, A.1    Magnuson, M.A.2    Wright, C.V.3    Moses, H.L.4
  • 46
    • 50249094553 scopus 로고    scopus 로고
    • Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos
    • Jones EA, Yuan L, Breant C, Watts RJ, Eichmann A, (2008) Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos. Development 135: 2479-2488.
    • (2008) Development , vol.135 , pp. 2479-2488
    • Jones, E.A.1    Yuan, L.2    Breant, C.3    Watts, R.J.4    Eichmann, A.5
  • 47
    • 34548740091 scopus 로고    scopus 로고
    • HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis
    • Wei G, Ku S, Ma GK, Saito S, Tang AA, et al. (2007) HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis. Proc Natl Acad Sci U S A 104: 13040-13045.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13040-13045
    • Wei, G.1    Ku, S.2    Ma, G.K.3    Saito, S.4    Tang, A.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.